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Thirty-five patients aged between 7 and 17\u00a0years underwent a comprehensive oral examination. Severity of MIH was graded using the MIH Treatment Need Index (MIH-TNI), OHRQoL using the Child Oral Health Impact Profile (COHIP-19). Clinical quality of restorations was assessed according to modified FDI-criteria, tooth sensitivity using the Schiff Cold Air Sensitivity Scale (SCASS). The mean age was 11.3\u2009\u00b1\u20093.0\u00a0years, 34% were female. On average, 6.9\u2009\u00b1\u20092.8 teeth were affected, 62,9% had hypersensitive teeth (SCASS\u2009\u2265\u20091). Eighty-nine percent of patients had received restorative care, with a mean of 3.3\u2009\u00b1\u20092.1 teeth restored, most often with composite, followed by fissure sealing. Nine percent of restorations failed by the FDI-criteria. Mean estimated survival times for success were 4.9\u00a0years (95% CI 3.5; 6.2) and 5.6\u00a0years (95% CI 5.0; 6.3) for fissure sealants and composite restorations, respectively. The mean COHIP-19 score was 64.3\u2009\u00b1\u20098.2 (max. possible score\u2009=\u200976). A higher severity of MIH-TNI correlated significantly with impaired OHRQoL (r<jats:sub>s<\/jats:sub>\u2009=\u2009\u2212 0.38, p\u2009=\u20090.013). However, this was not mirrored in multiple regression analysis. Despite the high rate of restorative treatment with an acceptable failure rate, OHRQoL is reduced in children with MIH. Many teeth affected by MIH remain sensitive. Further studies are needed to assess the benefits of different restorative options.<\/jats:p>","DOI":"10.1038\/s41598-024-51223-3","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T11:03:32Z","timestamp":1704711812000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Oral health-related quality of life and survival analysis after preventive and restorative treatment of molar-incisor hypomineralisation"],"prefix":"10.1038","volume":"14","author":[{"given":"Caroline","family":"Sekundo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Muscholl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Frese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"key":"51223_CR1","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1159\/000047479","volume":"35","author":"KL Weerheijm","year":"2001","unstructured":"Weerheijm, K. 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