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There hasn\u2019t been any research done on using metallic nanoparticles of different shapes with water as the base fluid. A radially symmetric but axially non-symmetric stenosis is used to depict the blood flow. Another significant aspect of our research is the study of symmetrical distribution of wall shearing stresses in connection with resistive impedance, as well as the rise of these quantities with the progression of stenosis. Shaping nanoparticles in accordance with the understanding of blood flow in arteries offers numerous possibilities for improving drug delivery, targeted therapies, and diagnostic imaging in the context of cardiovascular and other vascular-related diseases. Exact solutions for different flow quantities namely velocity, temperature, resistance impedance, boundary shear stress, and shearing stress at the stenosis throat, have been assessed. 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