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In this context, zinc\u2013magnesium (Zn\u2013Mg) alloy with successive contents of calcium silicate (CaSiO<jats:sub>3<\/jats:sub>) and silicon nitride (Si<jats:sub>3<\/jats:sub>N<jats:sub>4<\/jats:sub>) was prepared using powder metallurgy technique. After sintering, their phase composition and microstructure were investigated using the X-ray diffraction technique and scanning electron microscopy (SEM), respectively. Furthermore, their degradation behavior and ability to form hydroxyapatite (HA) layer on the sample surface after immersion in simulated body fluid (SBF) were monitored using weight loss measurements, inductively coupled plasma-atomic emission spectroscopy, and SEM. Moreover, their tribo-mechanical properties were measured. The results obtained showed that the successive contents of CaSiO<jats:sub>3<\/jats:sub> were responsible for improving the bioactivity behavior as indicated by a good formation of the HA layer on the samples\u2019 surface. Additionally, ceramic materials were responsible for a continuous decrease in the released ions in the SBF solution as indicated by the ICP results. The tribology properties were significantly improved even after exposure to different loads. Based on the above results, the prepared nanocomposites are promising for use in orthopedic applications.<\/jats:p>","DOI":"10.1038\/s41598-024-52648-6","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T17:03:35Z","timestamp":1706547815000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Tuning biodegradability, bone-bonding capacity, and wear resistance of zinc-30% magnesium intermetallic alloy for use in load-bearing bone applications"],"prefix":"10.1038","volume":"14","author":[{"given":"Rasha A.","family":"Youness","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed A.","family":"Taha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,29]]},"reference":[{"key":"52648_CR1","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1007\/s11517-020-02157-1","volume":"58","author":"A Bagherifard","year":"2020","unstructured":"Bagherifard, A. et al. 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