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As revealed by XRD pattern, the nanohybrids exhibits a rutile TiO<jats:sub>2<\/jats:sub> crystallites around 45\u00a0nm in size. The emergence of the Ti\u2013O\u2013Ti bond is identified by observing a peak between 400 and 800\u00a0cm<jats:sup>\u22121<\/jats:sup>. A wide bandgap (4.8\u00a0eV) has been observed in CTiO<jats:sub>2<\/jats:sub>@NPs, due to the quantum confinement effects and the oxygen vacancies reveal the intriguing potential of developed nanohybrids for various applications. Surface flaws were identified by observing an emission band at 382, 437, 482, 517, and 556\u00a0nm. They also exhibit better antibacterial performances using well diffusion method against <jats:italic>Staphylococcus aureus<\/jats:italic>, <jats:italic>Bacillus substilis<\/jats:italic>, <jats:italic>Klebsiella pneumonia<\/jats:italic>, and<jats:italic> Escherichia coli<\/jats:italic>. CTiO<jats:sub>2<\/jats:sub>@NPs were discovered to have free radical scavenging activity on DPPH analysis and exhibit IC<jats:sub>50<\/jats:sub> value as 95.80\u00a0\u03bcg\/mL and standard (Vitamin C) IC<jats:sub>50<\/jats:sub> is 87.62\u00a0\u03bcg\/mL. CTiO<jats:sub>2<\/jats:sub>@NPs exhibited better anticancer properties against the osteosarcoma (MG-63) cell line. All these findings suggest that there is a forum for further useful therapeutic applications. 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