{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T04:34:35Z","timestamp":1771994075192,"version":"3.50.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:00:00Z","timestamp":1708300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:00:00Z","timestamp":1708300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005713","name":"Technische Universit\u00e4t M\u00fcnchen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005713","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Several conventional cross-sectional studies have investigated the impact of the coronavirus disease (COVID-19) pandemic on patients with axial spondyloarthritis (axSpA) and reached contrary results regarding health and well-being. As analysis of web search data already provided insights into public interest and unmet needs, this study aimed to examine axSpA-related web searches before and during COVID-19 pandemic to gain a different perspective on the impact of COVID-19 on this disease. The Google Ads Keyword Planner was used to generate axSpA-related keywords and their monthly number of searches between June 2018 and November 2021 in Germany. These keywords were qualitatively classified into seven categories. A total of 538 axSpA-related keywords were used for the analysis. The number of axSpA-related searches increased during COVID-19 pandemic (before: n\u2009=\u20091,525,010 vs. during: n\u2009=\u20091,848,300), particularly searches for symptoms, disease outcomes, and causes, while interest in disease management and diagnosis decreased. This study demonstrated a shift in public interest in axSpA during COVID-19 in Germany and highlights an urgent expansion of telemedicine to be prepared for exceptional situations such as a pandemic.<\/jats:p>","DOI":"10.1038\/s41598-024-54047-3","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T05:02:14Z","timestamp":1708318934000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Change of perspective: impact of COVID-19 pandemic on axial spondyloarthritis-related web searches in Germany"],"prefix":"10.1038","volume":"14","author":[{"given":"Hannah","family":"Wecker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Ziehfreund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hindelang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Welcker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Zink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"54047_CR1","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/S0140-6736(16)31591-4","volume":"390","author":"J Sieper","year":"2017","unstructured":"Sieper, J. & Poddubnyy, D. Axial spondyloarthritis. Lancet 390, 73\u201384. https:\/\/doi.org\/10.1016\/S0140-6736(16)31591-4 (2017).","journal-title":"Lancet"},{"key":"54047_CR2","doi-asserted-by":"publisher","first-page":"157","DOI":"10.23750\/abm.v91i1.9397","volume":"91","author":"D Cucinotta","year":"2020","unstructured":"Cucinotta, D. & Vanelli, M. WHO Declares COVID-19 a pandemic. Acta Biomed. 91, 157\u2013160. https:\/\/doi.org\/10.23750\/abm.v91i1.9397 (2020).","journal-title":"Acta Biomed."},{"key":"54047_CR3","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/s12875-021-01471-3","volume":"22","author":"I Sch\u00e4fer","year":"2021","unstructured":"Sch\u00e4fer, I. et al. The effect of COVID-19 pandemic and lockdown on consultation numbers, consultation reasons and performed services in primary care: Results of a longitudinal observational study. BMC Fam. Pract. 22, 125. https:\/\/doi.org\/10.1186\/s12875-021-01471-3 (2021).","journal-title":"BMC Fam. Pract."},{"key":"54047_CR4","doi-asserted-by":"publisher","first-page":"113462","DOI":"10.1016\/j.psychres.2020.113462","volume":"293","author":"C Benke","year":"2020","unstructured":"Benke, C. et al. Lockdown, quarantine measures, and social distancing: Associations with depression, anxiety and distress at the beginning of the COVID-19 pandemic among adults from Germany. Psychiatry Res. 293, 113462. https:\/\/doi.org\/10.1016\/j.psychres.2020.113462 (2020).","journal-title":"Psychiatry Res."},{"key":"54047_CR5","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1136\/annrheumdis-2020-218705","volume":"80","author":"A Ciurea","year":"2021","unstructured":"Ciurea, A. et al. Impact of the COVID-19 pandemic on the disease course of patients with inflammatory rheumatic diseases: Results from the Swiss Clinical Quality Management cohort. Ann. Rheum. Dis. 80, 238\u2013241. https:\/\/doi.org\/10.1136\/annrheumdis-2020-218705 (2021).","journal-title":"Ann. Rheum. Dis."},{"key":"54047_CR6","doi-asserted-by":"publisher","first-page":"1759720X2110666","DOI":"10.1177\/1759720X211066685","volume":"14","author":"D Benavent","year":"2022","unstructured":"Benavent, D. et al. Poor health and functioning in patients with axial spondyloarthritis during the COVID-19 pandemic and lockdown: REUMAVID study (phase 1). Ther. Adv. Musculoskelet. Dis. 14, 1759720X211066685. https:\/\/doi.org\/10.1177\/1759720X211066685 (2022).","journal-title":"Ther. Adv. Musculoskelet. Dis."},{"key":"54047_CR7","doi-asserted-by":"publisher","first-page":"e11","DOI":"10.1016\/S2665-9913(20)30413-6","volume":"3","author":"H Marzo-Ortega","year":"2021","unstructured":"Marzo-Ortega, H. et al. COVID-19 in axial spondyloarthritis care provision: Helping to straighten the long and winding road. Lancet Rheumatol. 3, e11\u2013e13. https:\/\/doi.org\/10.1016\/S2665-9913(20)30413-6 (2021).","journal-title":"Lancet Rheumatol."},{"key":"54047_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-023-05273-x","author":"K Berr","year":"2023","unstructured":"Berr, K. et al. Analyzing web searches for axial spondyloarthritis in Germany: A novel approach to exploring interests and unmet needs. Rheumatol. Int. https:\/\/doi.org\/10.1007\/s00296-023-05273-x (2023).","journal-title":"Rheumatol. Int."},{"key":"54047_CR9","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1136\/postgradmedj-2019-137407","volume":"97","author":"Y-J Mei","year":"2021","unstructured":"Mei, Y.-J. et al. Using internet search data to explore the global public concerns in ankylosing spondylitis. Postgrad. Med. J. 97, 93\u201396. https:\/\/doi.org\/10.1136\/postgradmedj-2019-137407 (2021).","journal-title":"Postgrad. Med. J."},{"key":"54047_CR10","doi-asserted-by":"publisher","first-page":"e9","DOI":"10.1055\/a-1398-5417","volume":"83","author":"B Schuster","year":"2021","unstructured":"Schuster, B. et al. Retracing the COVID-19 Pandemic in Germany from a Public Perspective using Google Search Queries Related to \u201ccoronavirus\u201d (Retracing the COVID-19 Pandemic in Germany from a Public Perspective using Google Search Queries Related to \u201ccoronavirus\u201d). Gesundheitswesen 83, e9\u2013e14. https:\/\/doi.org\/10.1055\/a-1398-5417 (2021).","journal-title":"Gesundheitswesen"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-54047-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-54047-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-54047-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T09:05:24Z","timestamp":1708592724000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-54047-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,19]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["54047"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-54047-3","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,19]]},"assertion":[{"value":"16 May 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Parts of this study were financially supported by an unrestricted research grant from Novartis Pharma GmbH. HW, SZ, MH, and AZ declare that they have no conflict of interest. MW reports consulting, lectures, presentations, speakers\u2019 honoraria, manuscript writing, educational events or support for attending meetings and\/or travel from Novartis, Abbvie, and UCB.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"4044"}}