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We conducted a cross-sectional study to identify factors associated with diabetic nephropathy by questionnaires, using student\u2019s t-test, chi-square test, and multivariable logistic regression. Among 898 participants, 16.7% had diabetic nephropathy. Compared with non-diabetic nephropathy patients, the patients with diabetic nephropathy had significantly higher percentage with onset age of type 1 diabetes between puberty and under 30\u00a0years old (female\u2009\u2265\u200912 or male\u2009\u2265\u200913\u00a0years old to 29\u00a0years old), longer diabetes duration, having family history of diabetes and diabetic nephropathy, accompanied with hypertension, hyperlipidemia, or coronary artery disease (CAD). Compared with patients with onset age before puberty, the odds of diabetic nephropathy occurrence increased to 1.61 times in patients with onset age between puberty and under 30\u00a0years old (p\u2009=\u20090.012) after adjusting diabetes duration. Age of diabetes onset between puberty and under 30\u00a0years old, diabetes duration, HbA1c, hospital admission within 3\u00a0years, diabetic retinopathy, hypertension, systolic blood pressure (SBP), triglyceride levels, and use of angiotensin converting enzyme inhibitor (ACEI) and\/or angiotensin receptor blockers (ARB) were independent factors associated with diabetic nephropathy\u00a0Screening for proteinuria is important in daily clinical practice and should be part of diabetes self-management education for patients with type 1 diabetes.<\/jats:p>","DOI":"10.1038\/s41598-024-54137-2","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T05:02:36Z","timestamp":1707800556000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Age at onset of type 1 diabetes between puberty and 30\u00a0years old is associated with increased diabetic nephropathy 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