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However, subclinical changes to the heart in diabetes are likely to occur prior to the clinical presentation. This cross-sectional study aimed to compare left atrial function by echocardiography between 43 individuals with type 1 diabetes and 43 healthy controls, aged 10\u201330\u00a0years. All participants underwent echocardiography and 2D speckle tracking measurements for left atrial phase function parameters. Physical capacity was assessed by exercise test on a bicycle. Results showed that participants with type 1 diabetes had significantly lower left atrial function parameters than healthy controls (p\u2009&lt;\u20090.05). There was a significant negative correlation between HbA1c means and reservoir and conduit strain (p\u2009&lt;\u20090.05) and individuals with BMI\u2009&lt;\u200930 showed a lower left atrial stiffness (p\u2009&lt;\u20090.05). Individuals with type 1 diabetes and a higher physical capacity did not differ from their healthy peers. Results indicate that lower HbA1c levels, BMI\u2009&lt;\u200930 and a higher physical capacity are favourable in terms of left atrial function in children and young adults with type 1 diabetes mellitus. Left atrial strain by echocardiography might become a new important tool in assessing heart function in T1DM.<\/jats:p>","DOI":"10.1038\/s41598-024-54597-6","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T11:02:04Z","timestamp":1708167724000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Lower left atrial function in young individuals with type 1 diabetes mellitus compared to healthy controls: an echocardiographic study"],"prefix":"10.1038","volume":"14","author":[{"given":"Cecilia","family":"Fridolfsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Thegerstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"\u00c5kesson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Engvall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Blomstrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,17]]},"reference":[{"key":"54597_CR1","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1016\/S2213-8587(15)00292-2","volume":"3","author":"A Rosengren","year":"2015","unstructured":"Rosengren, A. et al. 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