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The developed mathematical model is validated against real cholera data. A sensitivity analysis of some of the model parameters is also conducted. The intervention rates are found to be very important parameters in reducing the values of the basic reproduction number. The existence and stability of equilibrium solutions to the mathematical model are also carried out using analytical methods. The effect of some model parameters on the stability of equilibrium solutions, number of infected individuals, number of susceptible individuals and bacteria density is rigorously analyzed. One very important finding of this research work is that keeping the vaccination rate fixed and varying the treatment and sanitation rates provide a rapid decline of infection. The fourth order Runge\u2013Kutta numerical scheme is implemented in MATLAB to generate the numerical solutions.<\/jats:p>","DOI":"10.1038\/s41598-024-55240-0","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T09:03:02Z","timestamp":1708938182000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Mathematical modeling of cholera dynamics with intrinsic growth considering constant interventions"],"prefix":"10.1038","volume":"14","author":[{"given":"Kewani Welay","family":"Brhane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulaziz Garba","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hina","family":"Hina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Homan","family":"Emadifar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"55240_CR1","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.mbs.2011.04.001","volume":"232","author":"JP Tian","year":"2011","unstructured":"Tian, J. 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