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Furthermore, the hospital\u2019s data from 1 April 2023 to 1 January 2024 was utilized for internal validation. In the modelling dataset, a total of 339 pairs of mothers and their newborns were included in the study and divided into two groups: patients (n\u2009=\u200984, 24.78%) and controls (n\u2009=\u2009255, 75.22%). Logistic regression analysis was performed to examine the relationship between various factors and outcome. The results showed that maternal age\u2009&lt;\u200926\u00a0years (odds ratio [OR]\u2009=\u20092.16, 95% confidence interval [CI] 1.06\u20134.42, p\u2009=\u20090.034), maternal gestational diabetes (OR\u2009=\u20092.17, 95% CI 1.11\u20134.27, p\u2009=\u20090.024), forceps assisted delivery (OR\u2009=\u20093.76, 95% CI 1.72\u20135.21, p\u2009=\u20090.032), umbilical cord winding (OR\u2009=\u20091.75, 95% CI 1.32\u20132.67, p\u2009=\u20090.041) and male neonatal sex (OR\u2009=\u20091.59, 95% CI 1.00\u20132.62, p\u2009=\u20090.050) were identified as independent factors influencing the outcome of neonatal clinical sepsis. A main effects model was developed incorporating these five significant factors, resulting in an area under the curve (AUC) value of 0.713 (95% CI 0.635\u20130.773) for predicting the occurrence of neonatal clinical sepsis. In the internal validation cohort, the AUC value of the model was 0.711, with a 95% CI of 0.592\u20130.808. A main effects model incorporating the five significant factors was constructed to help healthcare professionals make informed decisions and improve clinical outcomes.<\/jats:p>","DOI":"10.1038\/s41598-024-55783-2","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T14:04:13Z","timestamp":1709820253000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Development of risk prediction nomogram for neonatal sepsis in Group B Streptococcus-colonized mothers: a retrospective study"],"prefix":"10.1038","volume":"14","author":[{"given":"Mengqi","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanbing","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinye","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baomei","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangqiang","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,7]]},"reference":[{"issue":"12","key":"55783_CR1","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1007\/s12098-022-04360-4","volume":"89","author":"B Adhisivam","year":"2022","unstructured":"Adhisivam, B. 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