{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T11:30:09Z","timestamp":1745839809132},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T00:00:00Z","timestamp":1709424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T00:00:00Z","timestamp":1709424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This multicentre (22 centres in Turkey) retrospective cohort study aimed to assess the clinical outcomes of patients with neutropenic fever and SARS-CoV-2 positivity. Study period was 15 March 2020\u201315 August 2021. A total of 170 cases (58 female, aged 59\u2009\u00b1\u200915.5\u00a0years) that fulfilled the inclusion criteria were included in the study. One-month mortality rate (OMM) was 44.8%. The logistic regression analysis showed the following significant variables for the mentioned dependent variables: (i) achieving PCR negativity: receiving a maximum of 5\u00a0days of favipiravir (<jats:italic>p<\/jats:italic>\u2009=\u20090.005, OR 5.166, 95% CI 1.639\u201316.280); (ii) need for ICU: receiving glycopeptide therapy at any time during the COVID-19\/FEN episode (<jats:italic>p<\/jats:italic>\u2009=\u20090.001, OR 6.566, 95% CI 2.137\u201320.172), the need for mechanical ventilation (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, OR 62.042, 95% CI 9.528\u2013404.011); (iii) need for mechanical ventilation: failure to recover from neutropenia (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, OR 17.869, 95% CI 3.592\u201388.907), receiving tocilizumab therapy (<jats:italic>p<\/jats:italic>\u2009=\u20090.028, OR 32.227, 95% CI 1.469\u2013707.053), septic shock (<jats:italic>p<\/jats:italic>\u2009=\u20090.001, OR 15.4 96% CI 3.164\u201375.897), and the need for ICU (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, OR 91.818, 95% CI 15.360\u2013548.873), (iv) OMM: [mechanical ventilation (<jats:italic>p<\/jats:italic>\u2009=\u20090.001, OR 19.041, 95% CI 3.229\u2013112.286) and septic shock (<jats:italic>p<\/jats:italic>\u2009=\u20090.010, OR 5.589,95% CI 1.509\u201320.700)]. Although it includes a relatively limited number of patients, our findings suggest that COVID-19 and FEN are associated with significant mortality and morbidity.<\/jats:p>","DOI":"10.1038\/s41598-024-55886-w","type":"journal-article","created":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T18:01:22Z","timestamp":1709488882000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The clinical features, treatment and prognosis of neutropenic fever and Coronavirus disease 2019 results of the multicentre teos study"],"prefix":"10.1038","volume":"14","author":[{"given":"Dil\u015fah","family":"Ba\u015fkol Elik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eafak","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevil","family":"Alkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuna","family":"Demirdal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alper","family":"Sener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sel\u00e7uk","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"G\u00fczel Tun\u00e7can","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bircan","family":"Kayaaslan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahmet","family":"G\u00fcner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"Eser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasip","family":"Kahraman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serhat","family":"Birengel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elif Mukime","family":"Sar\u0131cao\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esma","family":"Ero\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"\u00c7\u00f6lkesen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erman","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hande","family":"Berk Cam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c7i\u011fdem","family":"Mermutluo\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eafak","family":"\u00d6zer Balin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fclden","family":"Sincan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilg\u00fcn","family":"Alt\u0131n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uluhan","family":"Sili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bedia Mutay","family":"Suntur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu\u011fba","family":"Arslan G\u00fclen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burak","family":"Deveci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabin","family":"Saba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eaban","family":"\u0130ncecik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fclden","family":"Eser Karl\u0131da\u011f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elif","family":"Hakko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damla","family":"Akda\u011f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fcseyin Ayta\u00e7","family":"Erdem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilal","family":"Sipahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Candan","family":"\u00c7icek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Sezai","family":"Ta\u015fbakan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meltem","family":"Ta\u015fbakan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fcsn\u00fc","family":"Pulluk\u00e7u","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tansu","family":"Yamazhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilgin","family":"Arda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sercan","family":"Ulusoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oguz Resat","family":"Sipahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,3]]},"reference":[{"issue":"4","key":"55886_CR1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.3345\/cep.2020.00493","volume":"63","author":"SE Park","year":"2020","unstructured":"Park, S. E. Epidemiology, virology, and clinical features of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19). Clin. Exp. Pediatr. 63(4), 119\u2013124 (2020).","journal-title":"Clin. Exp. Pediatr."},{"key":"55886_CR2","unstructured":"World health organization (WHO). Coronavirus disease (COVID-19) Dashboard. https:\/\/covid19.who.int\/ (2023)."},{"issue":"5","key":"55886_CR3","doi-asserted-by":"publisher","first-page":"105951","DOI":"10.1016\/j.ijantimicag.2020.105951","volume":"55","author":"H Li","year":"2020","unstructured":"Li, H., Liu, S. M., Yu, X. H., Tang, S. L. & Tang, C. K. Coronavirus disease 2019 (COVID-19): Current status and future perspective. Int. J. Antimicrob. Agents 55(5), 105951 (2020).","journal-title":"Int. J. Antimicrob. Agents"},{"issue":"1(suppl 5)","key":"55886_CR4","doi-asserted-by":"publisher","first-page":"v111","DOI":"10.1093\/annonc\/mdw325","volume":"27","author":"J Klastersky","year":"2016","unstructured":"Klastersky, J. et al. ESMO Guidelines Committee. Management of febrile neutropenia: ESMO clinical practice guidelines. Ann. Oncol. 27(1(suppl 5)), v111\u2013v118. https:\/\/doi.org\/10.1093\/annonc\/mdw325 (2016).","journal-title":"Ann. Oncol."},{"issue":"6","key":"55886_CR5","doi-asserted-by":"publisher","first-page":"e936","DOI":"10.1634\/theoncologist.2020-0213","volume":"25","author":"HO Al-Shamsi","year":"2020","unstructured":"Al-Shamsi, H. O. et al. A practical approach to the management of cancer patients during the novel Coronavirus Disease 2019 (COVID-19) pandemic: An international collaborative group. Oncologist 25(6), e936\u2013e945 (2020).","journal-title":"Oncologist"},{"issue":"12","key":"55886_CR6","doi-asserted-by":"publisher","first-page":"6656","DOI":"10.1172\/JCI141777","volume":"130","author":"GL Shah","year":"2020","unstructured":"Shah, G. L. et al. Favorable outcomes of COVID-19 in recipients of hematopoietic cell transplantation. J. Clin. Invest. 130(12), 6656\u20136667 (2020).","journal-title":"J. Clin. Invest."},{"issue":"2","key":"55886_CR7","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/s15010-018-1256-8","volume":"47","author":"OR Sipahi","year":"2019","unstructured":"Sipahi, O. R. et al. Daptomycin versus glycopeptides in the treatment of febrile neutropenia: Results of the Izmir matched cohort study. Infection 47(2), 259\u2013266 (2019).","journal-title":"Infection"},{"issue":"4","key":"55886_CR8","doi-asserted-by":"publisher","first-page":"e56","DOI":"10.1093\/cid\/cir073","volume":"52","author":"AG Freifeld","year":"2011","unstructured":"Freifeld, A. G. et al. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America. Clin. Infect. Dis. 52(4), e56\u2013e93 (2011).","journal-title":"Clin. Infect. Dis."},{"key":"55886_CR9","unstructured":"CDC Investigative Criteria for Suspected Cases of SARS-CoV-2 Reinfection (ICR). https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/index.html (2023)."},{"issue":"2","key":"55886_CR10","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1111\/ijcp.12279","volume":"68","author":"OR Sipahi","year":"2014","unstructured":"Sipahi, O. R. et al. Piperacillin\/tazobactam versus cefoperazone\/sulbactam in adult low-risk febrile neutropenia cases. Int. J. Clin. Pract. 68(2), 230\u2013235 (2014).","journal-title":"Int. J. Clin. Pract."},{"issue":"10285","key":"55886_CR11","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1016\/S0140-6736(21)00676-0","volume":"397","author":"RECOVERY Collaborative Group","year":"2021","unstructured":"RECOVERY Collaborative Group. Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): A randomised, controlled, open-label, platform trial. Lancet 397(10285), 1637\u20131645. https:\/\/doi.org\/10.1016\/S0140-6736(21)00676-0 (2021).","journal-title":"Lancet"},{"key":"55886_CR12","unstructured":"Uptodate. Laboratory features associated with severe COVID-19. https:\/\/www.uptodate.com\/contents\/image\/print?imageKey=ID%2F127820&topicKey=ID%2F127429&search=coronavirus-disease-2019-covid-19-multisystem-in&source=see_link (2023)."},{"issue":"3","key":"55886_CR13","doi-asserted-by":"publisher","first-page":"e234881","DOI":"10.1001\/jamanetworkopen.2023.4881","volume":"6","author":"CJ Baus","year":"2023","unstructured":"Baus, C. J. et al. Neutropenic fever\u2013associated admissions among patients with solid tumors receiving chemotherapy during the COVID-19 pandemic. JAMA Netw. Open 6(3), e234881. https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.4881 (2023).","journal-title":"JAMA Netw. Open"},{"key":"55886_CR14","doi-asserted-by":"publisher","first-page":"102305","DOI":"10.1016\/j.tmaid.2022.102305","volume":"47","author":"T Kaya","year":"2020","unstructured":"Kaya, T., Dilek, A., Ozaras, R., Sahin Balcik, O. & Leblebicioglu, H. COVID 19 and febrile neutropenia: Case report and systematic review. Travel Med. Infect. Dis. 47, 102305 (2020).","journal-title":"Travel Med. Infect. Dis."},{"issue":"3","key":"55886_CR15","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/S1470-2045(20)30096-6","volume":"21","author":"W Liang","year":"2020","unstructured":"Liang, W. et al. Cancer patients in SARS-CoV-2 infection: A nationwide analysis in China. Lancet Oncol. 21(3), 335\u2013337 (2020).","journal-title":"Lancet Oncol."},{"issue":"6","key":"55886_CR16","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/j.annonc.2021.02.024","volume":"32","author":"P Grivas","year":"2021","unstructured":"Grivas, P. et al. Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: A report from the COVID-19 and cancer consortium. Ann. Oncol. 32(6), 787\u2013800 (2021).","journal-title":"Ann. Oncol."},{"issue":"25","key":"55886_CR17","doi-asserted-by":"publisher","first-page":"2881","DOI":"10.1182\/blood.2020008824","volume":"136","author":"A Vijenthira","year":"2020","unstructured":"Vijenthira, A. et al. Outcomes of patients with hematologic malignancies and COVID-19: A systematic review and meta-analysis of 3377 patients. Blood 136(25), 2881\u20132892 (2020).","journal-title":"Blood"},{"key":"55886_CR18","doi-asserted-by":"crossref","unstructured":"Fatuyi, M., et al. Outcomes of patients hospitalized with neutropenic fever and COVID-19 infection: A nationwide analysis. Preprint at https:\/\/www.researchsquare.com\/article\/rs-2876881\/v1Bu (2023).","DOI":"10.21203\/rs.3.rs-2876881\/v1"},{"issue":"8","key":"55886_CR19","doi-asserted-by":"publisher","first-page":"886","DOI":"10.3855\/jidc.12520","volume":"14","author":"S Ceken","year":"2020","unstructured":"Ceken, S. et al. Evaluation of risk factors for mortality in febrile neutropenia. J. Infect. Dev. Ctr. 14(8), 886\u2013892 (2020).","journal-title":"J. Infect. Dev. Ctr."},{"issue":"16","key":"55886_CR20","doi-asserted-by":"publisher","first-page":"4205","DOI":"10.3390\/cancers13164205","volume":"13","author":"M Sereno","year":"2021","unstructured":"Sereno, M. et al. A multicenter analysis of the outcome of cancer patients with neutropenia and COVID-19 optionally treated with granulocyte-colony stimulating factor (G-CSF): A comparative analysis. Cancers 13(16), 4205 (2021).","journal-title":"Cancers"},{"issue":"1","key":"55886_CR21","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1186\/s13054-020-02950-2","volume":"24","author":"M Bauer","year":"2020","unstructured":"Bauer, M. et al. Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019- results from a systematic review and meta-analysis. Crit. Care 24(1), 239 (2020).","journal-title":"Crit. Care"},{"issue":"9","key":"55886_CR22","doi-asserted-by":"publisher","first-page":"e0204608","DOI":"10.1371\/journal.pone.0204608","volume":"13","author":"Y Cag","year":"2018","unstructured":"Cag, Y. et al. Development and validation of a modified quick SOFA scale for risk assessment in sepsis syndrome. PLoS One 13(9), e0204608 (2018).","journal-title":"PLoS One"},{"issue":"2","key":"55886_CR23","doi-asserted-by":"publisher","first-page":"e0246318","DOI":"10.1371\/journal.pone.0246318","volume":"16","author":"R Chang","year":"2021","unstructured":"Chang, R., Elhusseiny, K. M., Yeh, Y. C. & Sun, W. Z. COVID-19 ICU and mechanical ventilation patient characteristics and outcomes-A systematic review and meta-analysis. PLoS One 16(2), e0246318. https:\/\/doi.org\/10.1371\/journal.pone.0246318 (2021).","journal-title":"PLoS One"},{"issue":"12","key":"55886_CR24","doi-asserted-by":"publisher","first-page":"3349","DOI":"10.1002\/ccr3.3369","volume":"8","author":"P L\u00f3pez-Pereira","year":"2020","unstructured":"L\u00f3pez-Pereira, P. et al. Can COVID-19 cause severe neutropenia?. Clin. Case Rep. 8(12), 3349\u20133351. https:\/\/doi.org\/10.1002\/ccr3.3369 (2020).","journal-title":"Clin. Case Rep."},{"issue":"10","key":"55886_CR25","doi-asserted-by":"publisher","first-page":"e29105","DOI":"10.1002\/pbc.29105","volume":"68","author":"A Schatzman","year":"2021","unstructured":"Schatzman, A., Vandenheuvel, J., Villalobos, T. & Rooney, K. Transient leukopenia, thrombocytopenia, and severe neutropenia associated with acute SARS-CoV-2 infection. Pediatr. Blood Cancer 68(10), e29105 (2021).","journal-title":"Pediatr. Blood Cancer"},{"key":"55886_CR26","doi-asserted-by":"publisher","first-page":"105114","DOI":"10.1016\/j.phrs.2020.105114","volume":"161","author":"N Farina","year":"2020","unstructured":"Farina, N. et al. COVID-19: Pharmacology and kinetics of viral clearance. Pharmacol. Res. 161, 105114 (2020).","journal-title":"Pharmacol. Res."},{"issue":"1","key":"55886_CR27","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1186\/s12879-021-06164-x","volume":"21","author":"T Manabe","year":"2021","unstructured":"Manabe, T., Kambayashi, D., Akatsu, H. & Kudo, K. Favipiravir for the treatment of patients with COVID-19: A systematic review and meta-analysis. BMC Infect. Dis. 21(1), 489 (2021).","journal-title":"BMC Infect. Dis."},{"issue":"2","key":"55886_CR28","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.cmi.2021.11.007","volume":"28","author":"M Bartoletti","year":"2022","unstructured":"Bartoletti, M. et al. ESCMID COVID-19 living guidelines: Drug treatment and clinical management. Clin. Microbiol. Infect. 28(2), 222\u2013238 (2022).","journal-title":"Clin. Microbiol. Infect."},{"issue":"12","key":"55886_CR29","doi-asserted-by":"publisher","first-page":"3558","DOI":"10.7150\/jca.54205","volume":"12","author":"C Liu","year":"2021","unstructured":"Liu, C. et al. Severity of COVID-19 in Cancer patients versus patients without Cancer: A propensity score matching analysis. J. Cancer 12(12), 3558\u20133565 (2021).","journal-title":"J. Cancer"},{"issue":"9","key":"55886_CR30","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1001\/jamainternmed.2021.2209","volume":"181","author":"X Mariette","year":"2021","unstructured":"Mariette, X. et al. Effectiveness of tocilizumab in patients hospitalized with COVID-19: A follow-up of the CORIMUNO-TOCI-1 randomized clinical trial. JAMA Intern. Med. 181(9), 1241\u20131243 (2021).","journal-title":"JAMA Intern. Med."},{"key":"55886_CR31","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.jpeds.2020.04.051","volume":"222","author":"E Venturini","year":"2020","unstructured":"Venturini, E. et al. Severe neutropenia in infants with severe acute respiratory syndrome caused by the novel coronavirus 2019 infection. J. Pediatr. 222, 259\u2013261 (2020).","journal-title":"J. Pediatr."},{"issue":"1","key":"55886_CR32","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1186\/s12889-021-10759-z","volume":"21","author":"DK Kipourou","year":"2021","unstructured":"Kipourou, D. K. et al. Probabilities of ICU admission and hospital discharge according to patient characteristics in the designated COVID-19 hospital of Kuwait. BMC Public Health. 21(1), 799 (2021).","journal-title":"BMC Public Health."},{"issue":"1","key":"55886_CR33","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1159\/000519530","volume":"146","author":"M Brogan","year":"2022","unstructured":"Brogan, M. & Ross, M. J. The impact of chronic kidney disease on outcomes of patients with COVID-19 admitted to the intensive care unit. Nephron 146(1), 67\u201371 (2022).","journal-title":"Nephron"},{"key":"55886_CR34","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.jhin.2021.04.012","volume":"113","author":"WH Chong","year":"2021","unstructured":"Chong, W. H. & Neu, K. P. Incidence, diagnosis and outcomes of COVID-19-associated pulmonary aspergillosis (CAPA): A systematic review. J. Hosp. Infect. 113, 115\u2013129 (2021).","journal-title":"J. Hosp. Infect."},{"issue":"1","key":"55886_CR35","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s15010-021-01701-x","volume":"50","author":"WH Chong","year":"2022","unstructured":"Chong, W. H., Saha, B. K. & Neu, K. P. Comparing the clinical characteristics and outcomes of COVID-19-associate pulmonary aspergillosis (CAPA): A systematic review and meta-analysis. Infection 50(1), 43\u201356 (2022).","journal-title":"Infection"},{"issue":"4","key":"55886_CR36","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s11046-020-00462-9","volume":"185","author":"G Song","year":"2020","unstructured":"Song, G., Liang, G. & Liu, W. Fungal co-infections associated with global COVID-19 pandemic: A clinical and diagnostic perspective from China. Mycopathologia 185(4), 599\u2013606 (2020).","journal-title":"Mycopathologia"},{"issue":"1","key":"55886_CR37","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1080\/0284186X.2020.1854481","volume":"60","author":"G Larfors","year":"2021","unstructured":"Larfors, G., Pahnke, S., State, M., Fredriksson, K. & Pettersson, D. Covid-19 intensive care admissions and mortality among Swedish patients with cancer. Acta Oncol. 60(1), 32\u201334 (2021).","journal-title":"Acta Oncol."},{"issue":"6","key":"55886_CR38","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.3390\/cancers13061436","volume":"13","author":"A Bernard","year":"2021","unstructured":"Bernard, A. et al. Comparison of cancer patients to non-cancer patients among COVID-19 inpatients at a national level. Cancers 13(6), 1436 (2021).","journal-title":"Cancers"},{"issue":"6","key":"55886_CR39","doi-asserted-by":"publisher","first-page":"e2012270","DOI":"10.1001\/jamanetworkopen.2020.12270","volume":"3","author":"G Suleyman","year":"2020","unstructured":"Suleyman, G. et al. Clinical characteristics and morbidity associated with coronavirus disease 2019 in a series of patients in Metropolitan Detroit. JAMA Netw. Open 3(6), e2012270. https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.12270 (2020).","journal-title":"JAMA Netw. Open"},{"issue":"10","key":"55886_CR40","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1111\/j.1553-2712.2011.01185.x","volume":"18","author":"JC Stoltzfus","year":"2011","unstructured":"Stoltzfus, J. C. Logistic regression: A brief primer. Acad. Emerg. Med. 18(10), 1099\u20131104 (2011).","journal-title":"Acad. Emerg. Med."},{"issue":"2","key":"55886_CR41","doi-asserted-by":"publisher","first-page":"e434","DOI":"10.1093\/cid\/ciaa1179","volume":"73","author":"OR Sipahi","year":"2021","unstructured":"Sipahi, O. R. What should be the ideal definite Coronavirus Disease 2019 (COVID-19) case definition?. Clin. Infect. Dis. 73(2), e434\u2013e436 (2021).","journal-title":"Clin. Infect. Dis."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-55886-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-55886-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-55886-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T18:01:26Z","timestamp":1709488886000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-55886-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,3]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["55886"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-55886-w","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,3]]},"assertion":[{"value":"20 May 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"5218"}}