{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:49:55Z","timestamp":1792784995405,"version":"4.5.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"NIH CORE","award":["P30 EY08098"],"award-info":[{"award-number":["P30 EY08098"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Purpose was to study 3-dimensional choroidal contour at choroidal inner boundary (CIB) and choroidal outer boundary (COB) in healthy eyes. Healthy eyes imaged on wide field swept-source optical coherence tomography were included. Delineation of CIB and COB was done based on our previously reported methods. Quantitative analysis of the surfaces of CIB and COB was based on analyzing best fit spherical radius (R) (overall and sectoral). One hundred and seven eyes of 74 subjects with a mean age of 46.4\u2009\u00b1\u200919.3\u00a0years were evaluated. Overall, R COB (mean\u2009\u00b1\u2009SD: 22.5\u2009\u00b1\u20094.8\u00a0mm)\u2009&lt;\u2009R CIB (32.4\u2009\u00b1\u20099.4\u00a0mm). Central sector had the least R at COB (7.2\u2009\u00b1\u20095.9\u00a0mm) as well as CIB (25.1\u2009\u00b1\u200914.3\u00a0mm) across all age groups. Regression analysis between R (CIB) and age (r\u2009=\u2009\u22120.31, r\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090.09) showed negative correlation (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001) and that between R (COB) and age was positive (r\u2009=\u20090.26, r\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090.07) (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.01). To conclude, central sector is the steepest sector in comparison to all the other sectors. This is indicative of a prolate shape of choroidal contour at CIB and COB. Outer boundary of choroid is steeper than inner boundary across all age groups. However, with ageing, outer boundary becomes flatter and inner boundary becomes steeper.\n                  <\/jats:p>","DOI":"10.1038\/s41598-024-56376-9","type":"journal-article","created":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T10:03:48Z","timestamp":1710410628000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Three-dimensional choroidal contour mapping in healthy population"],"prefix":"10.1038","volume":"14","author":[{"given":"Supriya","family":"Arora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit Randhir","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Rosario","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Nasar","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amrish","family":"Selvam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arman","family":"Zarnegar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjana","family":"Harihar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinisha","family":"Sant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Alain","family":"Sahel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran Kumar","family":"Vupparaboina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Chhablani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,14]]},"reference":[{"key":"56376_CR1","doi-asserted-by":"publisher","first-page":"783","DOI":"10.3389\/fmed.2021.783519","volume":"8","author":"R Xie","year":"2021","unstructured":"Xie, R., Qiu, B., Chhablani, J. & Zhang, X. 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Dr Jose Alain Sahel: Pixium Vision, GenSight Biologics, Sparing Vision, Prophesee, and Chronolife. Dr Jay Chhablani is a consultant for Salutaris Medical Devices, Allergan, and OD-OS.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"6210"}}