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This study aimed to investigate HRV changes after TGA. A retrospective analysis of HRV included patients diagnosed with TGA between January 2015 and May 2020. The time and frequency domains of HRV were compared among three groups: early (&lt;\u20091\u00a0week after TGA, n\u2009=\u200919), late (1\u20134\u00a0weeks after TGA, n\u2009=\u200938), and healthy control (HC, n\u2009=\u200919). The Pearson\u2019s correlation between time and time-domain HRV was also examined. The standard deviation of NN intervals (SD\n                    <jats:sub>NN<\/jats:sub>\n                    ) (early, 47.2; late, 35.5; HC, 41.5;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.033) and root mean square of successive RR interval differences (RMSSD) (early, 38.5; late, 21.3; HC, 31.0;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.006) differed significantly among the three groups. Post-hoc analysis showed statistically significant differences only in the early and late groups in both SDNN (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.032) and RMSSD (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.006) values. However, the frequency domain with total power, low-frequency and high-frequency powers, and low-frequency\/high-frequency ratio did not differ. SD\n                    <jats:sub>NN<\/jats:sub>\n                    (Pearson correlation coefficient\u2009=\u2212\u20090.396,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.002) and RMSSD (Pearson correlation coefficient\u2009=\u2212\u20090.406,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.002) were negatively correlated with time after TGA. Changes in HRV occurred over time after the onset of TGA, with the pattern showing an increase in the first week and then a decrease within 4\u00a0weeks.\n                  <\/jats:p>","DOI":"10.1038\/s41598-024-57546-5","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T04:01:42Z","timestamp":1711166502000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Changes in heart rate variability over time from symptom onset of transient global amnesia"],"prefix":"10.1038","volume":"14","author":[{"given":"Soomi","family":"Cho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue Hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Jeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Kyung","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won-Joo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoung","family":"Heo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,23]]},"reference":[{"key":"57546_CR1","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1136\/jnnp.53.10.834","volume":"53","author":"J Hodges","year":"1990","unstructured":"Hodges, J. & Warlow, C. 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