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Although most active during labor, the non-pregnant uterus can exhibit activity of comparable magnitude to the early stages of labor. In this study, two types of flexible electrodes were utilized to measure the electrical activity of uterine smooth muscle in vivo in anesthetized, non-pregnant rats. Flexible printed circuit electrodes were placed on the serosal surface of the uterine horn of six anesthetized rats. Electrical activity was recorded for a duration of 20\u201330\u00a0min. Activity contained two components: high frequency activity (bursts) and an underlying low frequency \u2018slow wave\u2019 which occurred concurrently. These components had dominant frequencies of 6.82\u2009\u00b1\u20090.63\u00a0Hz for the burst frequency and 0.032\u2009\u00b1\u20090.0055\u00a0Hz for the slow wave frequency. There was a mean burst occurrence rate of 0.76\u2009\u00b1\u20090.23 bursts per minute and mean burst duration of 20.1\u2009\u00b1\u20096.5\u00a0s. The use of multiple high-resolution electrodes enabled 2D mapping of the initiation and propagation of activity along the uterine horn. 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