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We designed this retrospective cohort study to determine this relationship by analyzing the association between the lowest body temperature (T-lowest) on the first day of ICU admission and in-hospital mortality. In this study, 550 participants with non-traumatic SAH were chosen from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Multivariate Cox regression analysis showed that T-lowest was nonlinearity correlated with in-hospital mortality (HR\u2009=\u20090.72, 95% CI: 0.59\u20130.86, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). We divided the T-lowest into quartile groups. In comparison to reference group Q1 (31.30\u201336.06\u00a0\u2103), group Q3 (36.56\u201336.72\u00a0\u2103) had a 50% lower risk of death in the hospital (HR: 0.5, 95% CI: 0.28\u20130.87, <jats:italic>p<\/jats:italic>\u2009=\u20090.014). We further confirmed the curve-like relationship between T-lowest and in-hospital mortality using restricted cubic splines. The mortality is lowest when the T-lowest is close to 36.5\u00a0\u00b0C, and the risk of death is increased when the temperature is lower or higher than that. Our study demonstrates that in-hospital mortality is associated with T-lowest. Patients with non-traumatic SAH are at increased risk of death if their body temperature on the first day of ICU admission is too low.<\/jats:p>","DOI":"10.1038\/s41598-024-60657-8","type":"journal-article","created":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T03:19:29Z","timestamp":1714274369000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hypothermia on the first day of ICU admission leads to increased in-hospital mortality in patients with subarachnoid hemorrhage"],"prefix":"10.1038","volume":"14","author":[{"given":"Wenyuan","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingmian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfang","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahua","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,28]]},"reference":[{"key":"60657_CR1","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/s1474-4422(09)70126-7","volume":"8","author":"DJ Nieuwkamp","year":"2009","unstructured":"Nieuwkamp, D. 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