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We evaluated the parameters: root mean square error, Peak-to-Valley, and amplitude of the predominant frequency (Fourier Transform analysis) of a section of the High-Pass filter map in keratoconic and healthy cohorts. Furthermore, we have analyzed keratoconic eyes that presented dark\u2013light bands in this map to assess their period and orientation with the Fourier Transform. There are significant statistical differences (<jats:italic>p<\/jats:italic> value\u2009&lt;\u20090.001) between healthy and keratoconic eyes in the three parameters, demonstrating a tendency to increase with the severity of the disease. Otherwise, the quantification of the bands reveals that the width is independent of eye laterality and keratoconic stage as orientation, which tends to be oblique. In conclusion, the quantitative results obtained with t\u00b7eyede could help to diagnose and monitor the progression of keratoconus.<\/jats:p>","DOI":"10.1038\/s41598-024-60842-9","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T14:49:55Z","timestamp":1714574995000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparing the clinical applicability of wavefront phase imaging in keratoconus versus normal eyes"],"prefix":"10.1038","volume":"14","author":[{"given":"Carolina","family":"Belda-Para","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gonzalo","family":"Velarde-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Velasco-Oca\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan M.","family":"Trujillo-Sevilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00e1n","family":"Rodr\u00edguez-M\u00e9ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Rodr\u00edguez-Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Alejandre-Alba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Rodr\u00edguez-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M.","family":"Rodr\u00edguez-Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,1]]},"reference":[{"key":"60842_CR1","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1097\/ICO.0000000000002150","volume":"39","author":"H Hashemi","year":"2020","unstructured":"Hashemi, H. et al. 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