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In this study, we examined the prevalence of <jats:italic>Anaplasma<\/jats:italic> and <jats:italic>Ehrlichia<\/jats:italic> species in ticks and domesticated animals in Suizhou County, Hubei Province in the central China. We used PCR amplification and DNA sequencing of the 16S rRNA, <jats:italic>gro<\/jats:italic>EL, and <jats:italic>glt<\/jats:italic>A genes to analyze. We collected 1900 ticks, including 1981 <jats:italic>Haemaphysalis longicornis<\/jats:italic> and 9 <jats:italic>Rhipicephalus microplus<\/jats:italic>, 159 blood samples of goats (n\u2009=\u2009152), cattle (n\u2009=\u20094), and dogs (n\u2009=\u20093) from May to August of 2023. PCR products demonstrated that <jats:italic>Anaplasma bovis<\/jats:italic>, <jats:italic>Anaplasma capra<\/jats:italic>, and an <jats:italic>Ehrlichia<\/jats:italic> species were detected in the <jats:italic>H. longicornis<\/jats:italic> with the minimum infection rates (MIR) of 1.11%, 1.32%, and 0.05%, respectively; <jats:italic>A. bovis<\/jats:italic>, <jats:italic>A. capra<\/jats:italic>, and\u00a0unnamed <jats:italic>Anaplasma<\/jats:italic> sp. were detected in goats with an infection rate of 26.31%, 1.31% and 1.97%, respectively. <jats:italic>Anaplasma<\/jats:italic> and <jats:italic>Ehrlichia<\/jats:italic> species were not detected from cattle, dogs and <jats:italic>R. microplus<\/jats:italic> ticks. The genetic differences in the <jats:italic>gro<\/jats:italic>EL gene sequences of the <jats:italic>Anaplasma<\/jats:italic> in the current study were large, whereas the 16S rRNA and <jats:italic>glt<\/jats:italic>A gene sequences were less disparate. This study shows that ticks and goats in Suizhou County, Hubei Province carry multiple <jats:italic>Anaplasma<\/jats:italic> species and an <jats:italic>Ehrlichia<\/jats:italic> species, with relatively higher infection rate of <jats:italic>A. bovis<\/jats:italic> in goats. Our study indicates that multiple <jats:italic>Anaplasma<\/jats:italic> and <jats:italic>Ehrlichia<\/jats:italic> species exist in ticks and goats in the central China with potential to cause human infection.<\/jats:p>","DOI":"10.1038\/s41598-024-63267-6","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T12:01:42Z","timestamp":1717243302000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and genetic diversity of Anaplasma and Ehrlichia in ticks and domesticated animals in Suizhou County, Hubei Province, China"],"prefix":"10.1038","volume":"14","author":[{"given":"Ju","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-hui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang-zhi","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu-ju","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Fan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-ya","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-mei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-zheng","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-zhou","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-jie","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,1]]},"reference":[{"key":"63267_CR1","doi-asserted-by":"publisher","first-page":"101992","DOI":"10.1016\/j.ttbdis.2022.101992","volume":"13","author":"Y Yan","year":"2022","unstructured":"Yan, Y. et al. 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