{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T01:02:10Z","timestamp":1789952530767,"version":"4.0.1"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T00:00:00Z","timestamp":1717113600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T00:00:00Z","timestamp":1717113600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002332","name":"Semmelweis University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002332","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Affective temperaments have been shown to robustly affect infertility treatment success. However, identification of possible mediating factors through which they exert their influence is still lacking. A growing number of results suggest that adherence to recommended treatments may be such a mediator, on the one hand, because affective temperaments are known to influence adherence and, on the other hand, because non-adherence negatively influences the treatment outcome. Recommended treatment of infertility involves, beyond medications, dietary and lifestyle changes. The aim of this retrospective cohort study was to evaluate whether adherence to physician-prescribed diet and physical activity recommendations mediates the effect of affective temperaments on infertility treatment outcomes. Among 308 women who underwent infertility treatment in an Assisted Reproduction Center, affective temperaments, adherence to diet, adherence to physical exercise, and infertility treatment success (clinical pregnancy) were assessed besides detailed medical history and demographic parameters. Associations between affective temperaments, adherence to diet and recommended physical activity, and assisted reproduction outcomes were analyzed using generalized linear models and causal mediation analysis. Adherence to physical activity didn\u2019t have an effect, but diet adherence increased the odds of infertility treatment success by 130% suggesting its role as a potential mediator. Based on causal mediation analysis, higher depressive and anxious temperament scores were directly associated with 63% and 45% lower odds of achieving clinical pregnancy, respectively, with effects not mediated by diet adherence. Higher irritable temperament scores indirectly decreased the odds of achieving clinical pregnancy by 14%, mediated by diet adherence; while higher cyclothymic temperament scores decreased the odds of achieving clinical pregnancy both directly by 51% and indirectly, mediated by diet adherence by 11%. Our results suggest that diet adherence mediates the mechanism by which irritable and cyclothymic affective temperaments influence IVF treatment success. Since adherence is a modifiable risk factor of infertility treatment success, screening for affective temperaments may help to identify potentially high-risk non-adherent patient groups and offer patient-tailored treatment, which may help increase the chances of a successful pregnancy and live birth in women undergoing IVF treatment.<\/jats:p>","DOI":"10.1038\/s41598-024-63343-x","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T13:03:05Z","timestamp":1717160585000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Adherence to dietary recommendations mediates the effect of affective temperaments on infertility treatment outcomes"],"prefix":"10.1038","volume":"14","author":[{"given":"Georgina","family":"Szabo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judit","family":"Szigeti F.","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miklos","family":"Sipos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szabolcs","family":"Varbiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xenia","family":"Gonda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,31]]},"reference":[{"key":"63343_CR1","doi-asserted-by":"crossref","unstructured":"World Health Organization. WHO fact sheet on infertility. Global Reproductive Health 6(1), p e52, (Spring, 2021).","DOI":"10.1097\/GRH.0000000000000052"},{"key":"63343_CR2","doi-asserted-by":"publisher","first-page":"10952","DOI":"10.18632\/aging.102497","volume":"11","author":"H Sun","year":"2019","unstructured":"Sun, H. et al. Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990\u20132017: results from a global burden of disease study, 2017. Aging 11, 10952 (2019).","journal-title":"Aging"},{"key":"63343_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12958-016-0225-2","volume":"15","author":"VA Kushnir","year":"2017","unstructured":"Kushnir, V. A., Barad, D. H., Albertini, D. F., Darmon, S. K. & Gleicher, N. Systematic review of worldwide trends in assisted reproductive technology 2004\u20132013. Reprod. Biol. Endocrinol. 15, 1\u20139 (2017).","journal-title":"Reprod. Biol. Endocrinol."},{"key":"63343_CR4","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/1477-7827-11-66","volume":"11","author":"R Sharma","year":"2013","unstructured":"Sharma, R., Biedenharn, K. R., Fedor, J. M. & Agarwal, A. Lifestyle factors and reproductive health: Taking control of your fertility. Reprod. Biol. Endocrinol. 11, 66. https:\/\/doi.org\/10.1186\/1477-7827-11-66 (2013).","journal-title":"Reprod. Biol. Endocrinol."},{"key":"63343_CR5","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520932403","author":"F Szkodziak","year":"2020","unstructured":"Szkodziak, F., Krzy\u017canowski, J. & Szkodziak, P. Psychological aspects of infertility. A systematic review. J. Int. Med. Res. https:\/\/doi.org\/10.1177\/0300060520932403 (2020).","journal-title":"J. Int. Med. Res."},{"key":"63343_CR6","first-page":"399","volume":"4","author":"EMMI","year":"2021","unstructured":"EMMI. Az Emberi Er\u0151forr\u00e1sok Miniszt\u00e9riuma eg\u00e9szs\u00e9g\u00fcgyi szakmai ir\u00e1nyelve az infertilitas \u00e9s subfertilitas kivizsg\u00e1l\u00e1s\u00e1r\u00f3l \u00e9s az assziszt\u00e1lt reprodukci\u00f3s kezel\u00e9sekr\u0151l. Eg\u00e9szs\u00e9g\u00fcgyi K\u00f6zl\u00f6ny 4, 399\u2013441 (2021).","journal-title":"Eg\u00e9szs\u00e9g\u00fcgyi K\u00f6zl\u00f6ny"},{"key":"63343_CR7","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1097\/GCO.0000000000000069","volume":"26","author":"KL Rooney","year":"2014","unstructured":"Rooney, K. L. & Domar, A. D. The impact of lifestyle behaviors on infertility treatment outcome. Curr. Opin. Obstetr. Gynecol. 26, 181\u2013185 (2014).","journal-title":"Curr. Opin. Obstetr. Gynecol."},{"key":"63343_CR8","doi-asserted-by":"publisher","first-page":"141","DOI":"10.15296\/ijwhr.2019.24","volume":"7","author":"DE Mahoney","year":"2019","unstructured":"Mahoney, D. E., Russell, C. L. & Cheng, A. L. Medication adherence among women undergoing infertility treatment: A systematic review. Int. J. Women\u2019s Health Reprod. Sci. 7, 141\u2013149 (2019).","journal-title":"Int. J. Women\u2019s Health Reprod. Sci."},{"key":"63343_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/09637486.2020.1787958","volume":"72","author":"J Huang","year":"2020","unstructured":"Huang, J. et al. Adherence to healthy dietary patterns and outcomes of assisted reproduction: A systematic review and meta-analysis. Int. J. Food Sci. Nutr. 72, 1\u201312. https:\/\/doi.org\/10.1080\/09637486.2020.1787958 (2020).","journal-title":"Int. J. Food Sci. Nutr."},{"key":"63343_CR10","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1093\/humrep\/des408","volume":"28","author":"EC Haagen","year":"2013","unstructured":"Haagen, E. C. et al. Guideline adherence is worth the effort: a cost-effectiveness analysis in intrauterine insemination care. Hum. Reprod. 28, 357\u2013366. https:\/\/doi.org\/10.1093\/humrep\/des408 (2013).","journal-title":"Hum. Reprod."},{"key":"63343_CR11","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1093\/humupd\/dms031","volume":"18","author":"S Gameiro","year":"2012","unstructured":"Gameiro, S., Boivin, J., Peronace, L. & Verhaak, C. M. Why do patients discontinue fertility treatment? A systematic review of reasons and predictors of discontinuation in fertility treatment. Hum. Reprod. Update 18, 652\u2013669. https:\/\/doi.org\/10.1093\/humupd\/dms031 (2012).","journal-title":"Hum. Reprod. Update"},{"key":"63343_CR12","unstructured":"Gameiro, S. & Boivin, J. An evidence-based approach to counseling for fertility treatment compliance. Fertility counseling: Clinical guide and case studies, 265\u2013280 (2015)."},{"key":"63343_CR13","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1093\/humrep\/der178","volume":"26","author":"C Gnoth","year":"2011","unstructured":"Gnoth, C. et al. Final ART success rates: A 10 years survey. Hum. Reprod. 26, 2239\u20132246 (2011).","journal-title":"Hum. Reprod."},{"key":"63343_CR14","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.bpobgyn.2006.12.003","volume":"21","author":"TM Cousineau","year":"2007","unstructured":"Cousineau, T. M. & Domar, A. D. Psychological impact of infertility. Best Pract. Res. Clin. Obstetr. Gynaecol. 21, 293\u2013308 (2007).","journal-title":"Best Pract. Res. Clin. Obstetr. Gynaecol."},{"key":"63343_CR15","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.fertnstert.2015.05.035","volume":"104","author":"J Boivin","year":"2015","unstructured":"Boivin, J. & Gameiro, S. Evolution of psychology and counseling in infertility. Fertil. Steril. 104, 251\u2013259. https:\/\/doi.org\/10.1016\/j.fertnstert.2015.05.035 (2015).","journal-title":"Fertil. Steril."},{"key":"63343_CR16","unstructured":"Organization, W. H. Adherence to long-term therapies: evidence for action. (2003)."},{"key":"63343_CR17","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1590\/1516-4446-2020-0935","volume":"43","author":"M Solmi","year":"2021","unstructured":"Solmi, M. et al. How can we improve antidepressant adherence in the management of depression? A targeted review and 10 clinical recommendations. Braz. J. Psychiatry 43, 189\u2013202. https:\/\/doi.org\/10.1590\/1516-4446-2020-0935 (2021).","journal-title":"Braz. J. Psychiatry"},{"key":"63343_CR18","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.2147\/PPA.S155971","volume":"12","author":"LR Martin","year":"2018","unstructured":"Martin, L. R., Feig, C., Maksoudian, C. R., Wysong, K. & Faasse, K. A perspective on nonadherence to drug therapy: Psychological barriers and strategies to overcome nonadherence. Patient Prefer. Adher. 12, 1527\u20131535 (2018).","journal-title":"Patient Prefer. Adher."},{"key":"63343_CR19","doi-asserted-by":"publisher","first-page":"e57058","DOI":"10.1371\/journal.pone.0057058","volume":"8","author":"FE Van Dooren","year":"2013","unstructured":"Van Dooren, F. E. et al. Depression and risk of mortality in people with diabetes mellitus: A systematic review and meta-analysis. PloS one 8, e57058 (2013).","journal-title":"PloS one"},{"key":"63343_CR20","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1097\/YCO.0b013e32833299d4","volume":"23","author":"Z Rihmer","year":"2010","unstructured":"Rihmer, Z., Akiskal, K. K., Rihmer, A. & Akiskal, H. S. Current research on affective temperaments. Curr. Opin. Psychiatr. 23, 12\u201318. https:\/\/doi.org\/10.1097\/YCO.0b013e32833299d4 (2010).","journal-title":"Curr. Opin. Psychiatr."},{"key":"63343_CR21","doi-asserted-by":"publisher","DOI":"10.1192\/j.eurpsy.2021.2252","author":"A Miola","year":"2021","unstructured":"Miola, A., Baldessarini, R. J., Pinna, M. & Tondo, L. Relationships of affective temperament ratings to diagnosis and morbidity measures in major affective disorders. Eur. Psychiatry https:\/\/doi.org\/10.1192\/j.eurpsy.2021.2252 (2021).","journal-title":"Eur. Psychiatry"},{"key":"63343_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2021.110423","author":"M Vecsey-Nagy","year":"2021","unstructured":"Vecsey-Nagy, M. et al. The association between accelerated vascular aging and cyclothymic affective temperament in women. J. Psychosom Res. https:\/\/doi.org\/10.1016\/j.jpsychores.2021.110423 (2021).","journal-title":"J. Psychosom Res."},{"key":"63343_CR23","doi-asserted-by":"publisher","first-page":"9248247","DOI":"10.1155\/2019\/9248247","volume":"2019","author":"B Korosi","year":"2019","unstructured":"Korosi, B. et al. Association between cyclothymic affective temperament and age of onset of hypertension. Int. J. Hypertens 2019, 9248247. https:\/\/doi.org\/10.1155\/2019\/9248247 (2019).","journal-title":"Int. J. Hypertens"},{"key":"63343_CR24","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1038\/s41440-020-0513-2","volume":"44","author":"B Korsi","year":"2021","unstructured":"Korsi, B. et al. Evaluation of affective temperaments and arterial stiffness in different hypertension phenotypes. Hypertens Res. 44, 47\u201354. https:\/\/doi.org\/10.1038\/s41440-020-0513-2 (2021).","journal-title":"Hypertens Res."},{"key":"63343_CR25","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeaa356.239","author":"M Vecsey-Nagy","year":"2021","unstructured":"Vecsey-Nagy, M. et al. The association between early vascular aging and cyclothymic affective temperament. Eur. Heart J.-Cardiovasc. Imaging https:\/\/doi.org\/10.1093\/ehjci\/jeaa356.239 (2021).","journal-title":"Eur. Heart J.-Cardiovasc. Imaging"},{"key":"63343_CR26","doi-asserted-by":"publisher","DOI":"10.2991\/artres.k.191123.002","author":"B K\u0151r\u00f6si","year":"2019","unstructured":"K\u0151r\u00f6si, B. et al. Association between irritable affective temperament and nighttime peripheral and central systolic blood pressure in hypertension. Artery Res. https:\/\/doi.org\/10.2991\/artres.k.191123.002 (2019).","journal-title":"Artery Res."},{"key":"63343_CR27","doi-asserted-by":"publisher","first-page":"S849","DOI":"10.1016\/S0924-977X(17)31527-4","volume":"27","author":"B Korosi","year":"2017","unstructured":"Korosi, B. et al. The impact of currently recommended antihypertensive therapy on depression and other psychometric parameters: A prospective pilot study. Eur. Neuropsychopharm. 27, S849\u2013S850. https:\/\/doi.org\/10.1016\/S0924-977X(17)31527-4 (2017).","journal-title":"Eur. Neuropsychopharm."},{"key":"63343_CR28","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1159\/000357364","volume":"83","author":"A Eory","year":"2014","unstructured":"Eory, A. et al. Affective temperaments contribute to cardiac complications in hypertension independently of depression. Psychother. Psychosomatics 83, 187\u2013189 (2014).","journal-title":"Psychother. Psychosomatics"},{"key":"63343_CR29","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1556\/oh.2011.29245","volume":"152","author":"A E\u0151ry","year":"2011","unstructured":"E\u0151ry, A., Gonda, X., Torzsa, P., Kalabay, L. & Rihmer, Z. Affective temperaments: From neurobiological roots to clinical application. Orvosi. Hetilap. 152, 1879\u20131886. https:\/\/doi.org\/10.1556\/oh.2011.29245 (2011).","journal-title":"Orvosi. Hetilap."},{"key":"63343_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12991-015-0072-0","volume":"14","author":"A L\u00e1szl\u00f3","year":"2015","unstructured":"L\u00e1szl\u00f3, A. et al. Identification of hypertensive patients with dominant affective temperaments might improve the psychopathological and cardiovascular risk stratification: A pilot, case\u2013control study. Ann. General Psychiatry 14, 1\u20138 (2015).","journal-title":"Ann. General Psychiatry"},{"key":"63343_CR31","doi-asserted-by":"publisher","first-page":"247","DOI":"10.3109\/13814788.2013.868431","volume":"20","author":"A Eory","year":"2014","unstructured":"Eory, A. et al. Personality and cardiovascular risk: Association between hypertension and affective temperaments-a cross-sectional observational study in primary care settings. Eur. J. Gen. Pract. 20, 247\u2013252. https:\/\/doi.org\/10.3109\/13814788.2013.868431 (2014).","journal-title":"Eur. J. Gen. Pract."},{"key":"63343_CR32","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1556\/650.2021.32169","volume":"162","author":"C Hargittay","year":"2021","unstructured":"Hargittay, C. et al. The relationship between anxiety and diabetes. Orv. Hetil. 162, 1226\u20131232. https:\/\/doi.org\/10.1556\/650.2021.32169 (2021).","journal-title":"Orv. Hetil."},{"key":"63343_CR33","doi-asserted-by":"publisher","first-page":"4981","DOI":"10.2147\/DMSO.S342185","volume":"14","author":"N Lesiewska","year":"2021","unstructured":"Lesiewska, N. et al. Affective temperament and glycemic control-the psychological aspect of obesity and diabetes mellitus. Diabetes Metab. Syndrome Obesity Targets Ther. 14, 4981 (2021).","journal-title":"Diabetes Metab. Syndrome Obesity Targets Ther."},{"key":"63343_CR34","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.jpsychores.2021.110423","volume":"145","author":"M Vecsey-Nagy","year":"2021","unstructured":"Vecsey-Nagy, M. et al. The association between accelerated vascular aging and cyclothymic affective temperament in women. J. Psychosomat. Res. 145, 6. https:\/\/doi.org\/10.1016\/j.jpsychores.2021.110423 (2021).","journal-title":"J. Psychosomat. Res."},{"key":"63343_CR35","doi-asserted-by":"publisher","first-page":"21956","DOI":"10.1038\/s41598-023-47969-x","volume":"13","author":"G Szabo","year":"2023","unstructured":"Szabo, G., Szigeti, F. J., Sipos, M., Varbiro, S. & Gonda, X. Affective temperaments show stronger association with infertility treatment success compared to somatic factors, highlighting the role of personality focused interventions. Sci. Rep. 13, 21956 (2023).","journal-title":"Sci. Rep."},{"key":"63343_CR36","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1038\/s41398-022-02129-z","volume":"12","author":"G Szabo","year":"2022","unstructured":"Szabo, G., Fornaro, M., Dome, P., Varbiro, S. & Gonda, X. A bitter pill to swallow? Impact of affective temperaments on treatment adherence: a systematic review and meta-analysis. Transl. Psychiatry 12, 360 (2022).","journal-title":"Transl. Psychiatry"},{"key":"63343_CR37","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.jad.2007.03.016","volume":"106","author":"S R\u00f3zsa","year":"2008","unstructured":"R\u00f3zsa, S. et al. A study of affective temperaments in Hungary: Internal consistency and concurrent validity of the TEMPS-A against the TCI and NEO-PI-R. J. Affect. Disord. 106, 45\u201353. https:\/\/doi.org\/10.1016\/j.jad.2007.03.016 (2008).","journal-title":"J. Affect. Disord."},{"key":"63343_CR38","first-page":"147","volume":"21","author":"S R\u00f3zsa","year":"2006","unstructured":"R\u00f3zsa, S. et al. Affective temperaments: psychometric properties of the Hungarian TEMPS-A. Psychiatr. Hung 21, 147\u2013160 (2006).","journal-title":"Psychiatr. Hung"},{"key":"63343_CR39","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.jad.2004.12.001","volume":"85","author":"HS Akiskal","year":"2005","unstructured":"Akiskal, H. S., Akiskal, K. K., Haykal, R. F., Manning, J. S. & Connor, P. D. TEMPS-A: Progress towards validation of a self-rated clinical version of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire. J. Affect Disord 85, 3\u201316. https:\/\/doi.org\/10.1016\/j.jad.2004.12.001 (2005).","journal-title":"J. Affect Disord"},{"key":"63343_CR40","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoaa009","author":"TEGGOO Stimulation","year":"2020","unstructured":"Stimulation, T. E. G. G. O. O. et al. ESHRE guideline: ovarian stimulation for IVF\/ICSI\u2020. Hum. Reprod. Open https:\/\/doi.org\/10.1093\/hropen\/hoaa009 (2020).","journal-title":"Hum. Reprod. Open"},{"key":"63343_CR41","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1093\/humupd\/dmq015","volume":"16","author":"LL van Loendersloot","year":"2010","unstructured":"van Loendersloot, L. L. et al. Predictive factors in in vitro fertilization (IVF): A systematic review and meta-analysis. Hum. Reproduction Update 16, 577\u2013589. https:\/\/doi.org\/10.1093\/humupd\/dmq015 (2010).","journal-title":"Hum. Reproduction Update"},{"key":"63343_CR42","doi-asserted-by":"publisher","first-page":"943","DOI":"10.2337\/diacare.23.7.943","volume":"23","author":"DJ Toobert","year":"2000","unstructured":"Toobert, D. J., Hampson, S. E. & Glasgow, R. E. The summary of diabetes self-care activities measure: results from 7 studies and a revised scale. Diabetes Care 23, 943\u2013950. https:\/\/doi.org\/10.2337\/diacare.23.7.943 (2000).","journal-title":"Diabetes Care"},{"key":"63343_CR43","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/j.1467-9280.2007.01882.x","volume":"18","author":"MS Fritz","year":"2007","unstructured":"Fritz, M. S. & MacKinnon, D. P. Required sample size to detect the mediated effect. Psychol. Sci. 18, 233\u2013239 (2007).","journal-title":"Psychol. Sci."},{"issue":"3","key":"63343_CR44","doi-asserted-by":"publisher","first-page":"hoac022","DOI":"10.1093\/hropen\/hoac022","volume":"2022","author":"C Wyns","year":"2022","unstructured":"Wyns, C. et al. ART in Europe, 2018: results generated from European registries by ESHRE. Hum. Reprod. Open 2022(3), hoac022 (2022).","journal-title":"Hum. Reprod. Open"},{"key":"63343_CR45","doi-asserted-by":"publisher","DOI":"10.17433\/978-3-17-031899-1","volume-title":"Der Traum vom eigenen Kind: psychologische Hilfen bei unerf\u00fclltem Kinderwunsch","author":"T Wischmann","year":"2016","unstructured":"Wischmann, T. & Stammer, H. Der Traum vom eigenen Kind: psychologische Hilfen bei unerf\u00fclltem Kinderwunsch (Kohlhammer Verlag, 2016)."},{"key":"63343_CR46","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1093\/humupd\/dmq015","volume":"16","author":"L Van Loendersloot","year":"2010","unstructured":"Van Loendersloot, L. et al. Predictive factors in in vitro fertilization (IVF): A systematic review and meta-analysis. Hum. Reprod. Update 16, 577\u2013589 (2010).","journal-title":"Hum. Reprod. Update"},{"key":"63343_CR47","first-page":"76","volume":"16","author":"RD Rezaeiye","year":"2022","unstructured":"Rezaeiye, R. D., Mehrara, A., Pour, A. M. A., Fallahi, J. & Forouhari, S. Impact of various parameters as predictors of the success rate of in vitro fertilization. Int. J. Fertil. Steril. 16, 76 (2022).","journal-title":"Int. J. Fertil. Steril."},{"key":"63343_CR48","doi-asserted-by":"publisher","DOI":"10.33668\/hn.24.016","author":"J Nemcsik","year":"2020","unstructured":"Nemcsik, J., Batta, D., K\u0151r\u00f6si, B. & Rihmer, Z. A cyclothym affekt\u00edv temperamentum \u00e9s a hypertonia kapcsolata. Hypertonia \u00e9s Nephrologia https:\/\/doi.org\/10.33668\/hn.24.016 (2020).","journal-title":"Hypertonia \u00e9s Nephrologia"},{"key":"63343_CR49","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1016\/j.jad.2021.08.105","volume":"295","author":"E Scumaci","year":"2021","unstructured":"Scumaci, E. et al. Affective temperaments and obesity: Is there an association with binge eating episodes and multiple weight cycling?. J. Affect. Disord. 295, 967\u2013973. https:\/\/doi.org\/10.1016\/j.jad.2021.08.105 (2021).","journal-title":"J. Affect. Disord."},{"key":"63343_CR50","doi-asserted-by":"publisher","first-page":"S67","DOI":"10.1016\/s0165-0327(12)70010-1","volume":"142","author":"C Gois","year":"2012","unstructured":"Gois, C., Akiskal, H., Akiskal, K. & Figueira, M. L. The relationship between temperament, diabetes and depression. J. Affect. Disord. 142, S67\u2013S71. https:\/\/doi.org\/10.1016\/s0165-0327(12)70010-1 (2012).","journal-title":"J. Affect. Disord."},{"key":"63343_CR51","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3109\/08039488.2015.1067330","volume":"70","author":"SV Buturak","year":"2016","unstructured":"Buturak, S. V., Emel, E. B. & Ko\u00e7ak, O. M. The effect of temperament on the treatment adherence of bipolar disorder type I. Nord. J. Psychiatry 70, 176\u2013182. https:\/\/doi.org\/10.3109\/08039488.2015.1067330 (2016).","journal-title":"Nord. J. Psychiatry"},{"key":"63343_CR52","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.jad.2013.07.004","volume":"151","author":"M Fornaro","year":"2013","unstructured":"Fornaro, M. et al. Treatment adherence towards prescribed medications in bipolar-II acute depressed patients: Relationship with cyclothymic temperament and \u201ctherapeutic sensation seeking\u201d in response towards subjective intolerance to pain. J. Affect. Disord. 151, 596\u2013604. https:\/\/doi.org\/10.1016\/j.jad.2013.07.004 (2013).","journal-title":"J. Affect. Disord."},{"key":"63343_CR53","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.jad.2014.08.042","volume":"170","author":"M Innamorati","year":"2015","unstructured":"Innamorati, M. et al. Cyclothymic temperament rather than polarity is associated with hopelessness and suicidality in hospitalized patients with mood disorders. J. Affect Disord. 170, 161\u2013165 (2015).","journal-title":"J. Affect Disord."},{"key":"63343_CR54","doi-asserted-by":"publisher","first-page":"643395","DOI":"10.3389\/fpsyg.2021.643395","volume":"12","author":"R Zhou","year":"2021","unstructured":"Zhou, R., Cao, Y.-M., Liu, D. & Xiao, J.-S. Pregnancy or psychological outcomes of psychotherapy interventions for infertility: A meta-analysis. Front. Psychol. 12, 643395 (2021).","journal-title":"Front. Psychol."},{"key":"63343_CR55","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.ejogrb.2021.02.012","volume":"259","author":"N Katyal","year":"2021","unstructured":"Katyal, N., Poulsen, C. M., Knudsen, U. B. & Frederiksen, Y. The association between psychosocial interventions and fertility treatment outcome: A systematic review and meta-analysis. Eur. J. Obstetr. Gynecol. Reprod. Biol. 259, 125\u2013132 (2021).","journal-title":"Eur. J. Obstetr. Gynecol. Reprod. Biol."},{"key":"63343_CR56","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1093\/humupd\/dmp002","volume":"15","author":"K H\u00e4mmerli","year":"2009","unstructured":"H\u00e4mmerli, K., Znoj, H. & Barth, J. The efficacy of psychological interventions for infertile patients: A meta-analysis examining mental health and pregnancy rate. Hum. Reprod. Update 15, 279\u2013295 (2009).","journal-title":"Hum. Reprod. Update"},{"key":"63343_CR57","doi-asserted-by":"publisher","first-page":"2142777","DOI":"10.1080\/0167482X.2022.2142777","volume":"44","author":"J-Y Ha","year":"2023","unstructured":"Ha, J.-Y., Park, H.-J. & Ban, S.-H. Efficacy of psychosocial interventions for pregnancy rates of infertile women undergoing in vitro fertilization: A systematic review and meta-analysis. J. Psychos. Obstetr. Gynecol. 44, 2142777 (2023).","journal-title":"J. Psychos. Obstetr. Gynecol."},{"key":"63343_CR58","doi-asserted-by":"publisher","first-page":"e006592","DOI":"10.1136\/bmjopen-2014-006592","volume":"5","author":"Y Frederiksen","year":"2015","unstructured":"Frederiksen, Y., Farver-Vestergaard, I., Skovg\u00e5rd, N. G., Ingerslev, H. J. & Zachariae, R. Efficacy of psychosocial interventions for psychological and pregnancy outcomes in infertile women and men: A systematic review and meta-analysis. BMJ Open 5, e006592 (2015).","journal-title":"BMJ Open"},{"key":"63343_CR59","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1093\/humupd\/dmac034","volume":"29","author":"L Dube","year":"2023","unstructured":"Dube, L., Bright, K., Hayden, K. A. & Gordon, J. L. Efficacy of psychological interventions for mental health and pregnancy rates among individuals with infertility: A systematic review and meta-analysis. Hum. Reprod. Update 29, 71\u201394 (2023).","journal-title":"Hum. Reprod. Update"},{"key":"63343_CR60","doi-asserted-by":"publisher","DOI":"10.1080\/02648725.2023.2213080","author":"C Bian","year":"2023","unstructured":"Bian, C., Cao, J., Chen, K., Xia, X. & Yu, X. Effectiveness of psychological interventions on pregnancy rates in infertile women undergoing assisted reproductive technologies: A meta-analysis of randomised controlled trials. Biotechnol. Genetic Eng. Rev. https:\/\/doi.org\/10.1080\/02648725.2023.2213080 (2023).","journal-title":"Biotechnol. Genetic Eng. Rev."},{"key":"63343_CR61","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1080\/09513590.2021.1871892","volume":"37","author":"L Del Pup","year":"2021","unstructured":"Del Pup, L. & Cagnacci, A. IMPROVE lifestyle in polycystic ovary syndrome: A systematic strategy. Gynecol. Endocrinol. 37, 875\u2013878. https:\/\/doi.org\/10.1080\/09513590.2021.1871892 (2021).","journal-title":"Gynecol. Endocrinol."},{"key":"63343_CR62","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1093\/bja\/aev541","volume":"116","author":"U Del Gurunathan","year":"2016","unstructured":"Gurunathan, U. & Myles, P. S. Limitations of body mass index as an obesity measure of perioperative risk. BJA: British J. Anaesthesia 116, 319\u2013321 (2016).","journal-title":"BJA: British J. Anaesthesia"},{"key":"63343_CR63","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/s2213-8587(13)70062-7","volume":"1","author":"N Stefan","year":"2013","unstructured":"Stefan, N., H\u00e4ring, H. U., Hu, F. B. & Schulze, M. B. Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications. Lancet Diabetes Endocrinol. 1, 152\u2013162. https:\/\/doi.org\/10.1016\/s2213-8587(13)70062-7 (2013).","journal-title":"Lancet Diabetes Endocrinol."},{"key":"63343_CR64","doi-asserted-by":"publisher","first-page":"126","DOI":"10.31083\/j.ceog5006126","volume":"50","author":"K Riess","year":"2023","unstructured":"Riess, K., Zippl, A. L., Reh, L., Feil, K. & Toth, B. Prevalence of LOW and high BMI in patients with infertility. Clin. Exp. Obst. Gynecol. 50, 126 (2023).","journal-title":"Clin. Exp. Obst. Gynecol."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-63343-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-63343-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-63343-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T13:15:41Z","timestamp":1717161341000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-63343-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,31]]},"references-count":64,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["63343"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-63343-x","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,31]]},"assertion":[{"value":"21 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"12544"}}