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The motivation of this paper is to explore the impact of the visual information transmission pathway (V\u2013H pathway) on AD, and the following feature were observed: Hemoglobin expression on the V\u2013H pathway becomes dysregulated as AD occurs so as to the pathway becomes dysfunctional. According to the feature, the following conclusion was proposed: As AD occurs, abnormal tau proteins penetrate bloodstream and arrive at the brain regions of the pathway. Then the tau proteins or other toxic substances attack hemoglobin molecules. Under the attack, hemoglobin expression becomes more dysregulated. 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