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A holistic approach integrating well-being assessment could improve disease management. Since a consensus definition of well-being in psoriasis is not available, we aim to achieve a multidisciplinary consensus on well-being definition and its components. A literature review and consultation with psoriasis patients facilitated the design of a two-round Delphi questionnaire targeting healthcare professionals and psoriasis patients. A total of 261 panellists (65.1% patients with psoriasis, 34.9% healthcare professionals) agreed on the dimensions and components that should integrate the concept of well-being: emotional dimension (78.9%) [stress (83.9%), mood disturbance (85.1%), body image (83.9%), stigma\/shame (75.1%), self-esteem (77.4%) and coping\/resilience (81.2%)], physical dimension (82.0%) [sleep quality (81.6%), pain\/discomfort (80.8%), itching (83.5%), extracutaneous manifestations (82.8%), lesions in visible areas (84.3%), lesions in functional areas (85.8%), and sex life (78.2%)], social dimension (79.5%) [social relationships (80.8%), leisure\/recreational activities (80.3%), support from family\/friends (76.6%) and work\/academic life (76.5%)], and satisfaction with disease management (78.5%) [treatment (78.2%), information received (75.6%) and medical care provided by the dermatologist (80.1%)]. This well-being definition reflects patients\u2019 needs and concerns. Therefore, addressing them in psoriasis will optimise management, contributing to better outcomes and restoring normalcy to the patient\u2019s life.<\/jats:p>","DOI":"10.1038\/s41598-024-64738-6","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T14:03:09Z","timestamp":1719237789000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Defining well-being in psoriasis: A Delphi consensus among healthcare professionals and patients"],"prefix":"10.1038","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0676-1260","authenticated-orcid":false,"given":"Esteban","family":"Daud\u00e9n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6007-7320","authenticated-orcid":false,"given":"I.","family":"Belinch\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6835-2868","authenticated-orcid":false,"given":"E.","family":"Colominas-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Coto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4807-3551","authenticated-orcid":false,"given":"P.","family":"de la Cueva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6735-8459","authenticated-orcid":false,"given":"F.","family":"Gallardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1800-6198","authenticated-orcid":false,"given":"J. 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IB acted as a consultant and\/or speaker for and\/or participated in clinical trials sponsored by companies that manufacture drugs used for the treatment of psoriasis, including Janssen Pharmaceuticals Inc, Almirall SA, Lilly, AbbVie, Novartis, Celgene, Biogen, Amgen, Leo-Pharma, UCB, Pfizer-Wyeth, and MSD. ECG has received payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Amgen and Abbvie, and has received support for attending meetings and\/or travels from UCB pharma. PC has received payment or honoraria for lectures, presentations, speakers bureaus, manuscripts writing or educational events from Almirall, Abbvie, Amgen-Celgene, Sanofi. PDLC has received consulting fees or honoraria for lectures, presentations, speakers bureaus manuscript writing or educational events or support for attending meetings and\/or travel or has participated on Data Safety Monitoring Board or Advisory Board from Abbvie, Almirall, Amgen, Boehringer, Celgene, Janssen., LEO Pharma, Lilly, MSD, Novartis, Pfizer, Roche, Sanofi and UCB. SR has received payment or honoraria for lectures, presentations, speakers bureaus manuscript writing or educational events from Almirall, Abbvie, Leo Pharma, Lilly, UCB, Novartis, BMS, Boehringer. LL and MC work for an independent research entity that received funding from Almirall to coordinate and conduct the project. FG, ER, JLP and RRV declare no conflicts of interest in this work.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"14519"}}