{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:28:50Z","timestamp":1790231330652,"version":"4.1.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T00:00:00Z","timestamp":1718928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T00:00:00Z","timestamp":1718928000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002839","name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002839","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite a 15% misplacement rate of screws in idiopathic scoliosis surgery, little is known about the relationship between pedicles and nerve structures in the entire thoracic curve. This study aimed to explore the spinal cord\u2019s proximity to the pedicle wall at each thoracic vertebra in the entire thoracic curve, while considering different anatomical changes. Spinal cord to medial pedicle distances were measured on magnetic resonance imaging in 73 patients who underwent posterior spinal fusion with pedicle screw instrumentation. Associations with different variables were examined. A total of 51 patients (69.9%) showed a distance within 2\u00a0mm at the apex vertebra on the concave side, more than 50% had a distance within 2\u00a0mm in the next thoracic vertebra level above and below, and more than 25% two levels above and below. Weak correlations were found between proximity of the spinal cord at the apex vertebra and vertebra\u2019s level and Cobb angle on the concave side (r\u2009=\u2009\u2212\u00a00.310,\u00a0P\u2009=\u20090.008, r\u2009=\u20090.380,\u00a0P\u2009=\u20090.001, respectively). These results emphasize the importance of thorough assessment when placing thoracic pedicle screws in idiopathic scoliosis patients. Further research is warranted to develop surgical strategies aimed at preventing potentially neurological complications resulting from screw misplacement.<\/jats:p>","DOI":"10.1038\/s41598-024-64971-z","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T14:02:24Z","timestamp":1718978544000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["In idiopathic scoliosis distances of spinal cord to thoracic pedicle are within 2\u00a0mm in a large region of the thoracic apex"],"prefix":"10.1038","volume":"14","author":[{"given":"Joost A.","family":"Burger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Pumberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike","family":"Sch\u00f6mig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,21]]},"reference":[{"key":"64971_CR1","doi-asserted-by":"publisher","first-page":"E465","DOI":"10.1097\/BRS.0b013e3181d1021a","volume":"35","author":"JM Hicks","year":"2010","unstructured":"Hicks, J. M., Singla, A., Shen, F. H. & Arlet, V. Complications of pedicle screw fixation in scoliosis surgery: A systematic review. Spine (Phila Pa 1976) 35, E465-470. https:\/\/doi.org\/10.1097\/BRS.0b013e3181d1021a (2010).","journal-title":"Spine (Phila Pa 1976)"},{"key":"64971_CR2","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1097\/00007632-200005150-00008","volume":"25","author":"UR Liljenqvist","year":"2000","unstructured":"Liljenqvist, U. R., Link, T. M. & Halm, H. F. Morphometric analysis of thoracic and lumbar vertebrae in idiopathic scoliosis. Spine (Phila Pa 1976) 25, 1247\u20131253. https:\/\/doi.org\/10.1097\/00007632-200005150-00008 (2000).","journal-title":"Spine (Phila Pa 1976)"},{"key":"64971_CR3","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1007\/s11999-016-5188-2","volume":"475","author":"CM Davis","year":"2017","unstructured":"Davis, C. M. et al. Is there asymmetry between the concave and convex pedicles in adolescent idiopathic scoliosis? A CT investigation. Clin. Orthop. Relat. Res. 475, 884\u2013893. https:\/\/doi.org\/10.1007\/s11999-016-5188-2 (2017).","journal-title":"Clin. Orthop. Relat. Res."},{"key":"64971_CR4","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1097\/00007632-200109150-00022","volume":"26","author":"SI Suk","year":"2001","unstructured":"Suk, S. I., Kim, W. J., Lee, S. M., Kim, J. H. & Chung, E. R. Thoracic pedicle screw fixation in spinal deformities: Are they really safe?. Spine (Phila Pa 1976) 26, 2049\u20132057. https:\/\/doi.org\/10.1097\/00007632-200109150-00022 (2001).","journal-title":"Spine (Phila Pa 1976)"},{"key":"64971_CR5","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1007\/s005860050147","volume":"8","author":"P Papin","year":"1999","unstructured":"Papin, P., Arlet, V., Marchesi, D., Rosenblatt, B. & Aebi, M. Unusual presentation of spinal cord compression related to misplaced pedicle screws in thoracic scoliosis. Eur. 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