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Here, we investigated whether maternal <jats:italic>Schistosoma haematobium<\/jats:italic> affects maternal or cord vitamin D status as well as birth outcomes. In a prospective cross-sectional study of pregnant women conducted in Lambar\u00e9n\u00e9, Gabon, we diagnosed maternal parasitic infections in blood, urine and stool. At delivery we measured vitamin D in maternal and cord blood. <jats:italic>S. haematobium<\/jats:italic>, soil-transmitted helminths, and microfilariae were found at prevalences of 30.2%, 13.0%, and 8.8%, respectively. Insufficient vitamin D and calcium levels were found in 28% and 15% of mothers, and in 11.5% and 1.5% of newborns. Mothers with adequate vitamin D had lower risk of low birthweight babies (aOR\u2009=\u20090.11, 95% CI 0.02\u20130.52, <jats:italic>p<\/jats:italic>\u2009=\u20090.01), whilst offspring of primipars had low cord vitamin D levels, and low vitamin D levels increased the risk of maternal inflammation. Maternal filariasis was associated with low calcium levels, but other helminth infections affected neither vitamin D nor calcium levels in either mothers or newborns. Healthy birth outcomes require maintenance of adequate vitamin D and calcium levels. Chronic maternal helminth infections do not disrupt those levels in a semi-rural setting in sub-Saharan Africa.<\/jats:p>","DOI":"10.1038\/s41598-024-65232-9","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T13:01:38Z","timestamp":1719493298000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes"],"prefix":"10.1038","volume":"14","author":[{"given":"S\u00e8yigb\u00e9na P. 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