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The obtained magnetized inorganic-bioorganic nanohybrid characterized by Fourier transform infrared spectroscopy\u00a0(FT-IR), vibrating-sample magnetometry\u00a0(VSM), field emission scanning electron microscopy\u00a0(FESEM), energy-dispersive X-ray spectroscopy\u00a0(EDAX), transmission electron microscopy\u00a0(TEM), thermogravimetric analysis\/differential scanning calorimetry\u00a0(TGA\/DSC), X-ray fluorescence\u00a0(XRF), and X-Ray diffraction (XRD)\u00a0analysis. A facile synthesis of some tricyclic dihydro-spiro[chromeno[2,3-<jats:italic>c<\/jats:italic>]pyrazole-4,2\u2032-indene]triones and dihydro-spiro[chromeno[2,3-<jats:italic>c<\/jats:italic>]pyrazole-4,3\u2032-indoline]diones via domino four-component one-pot reaction of various hydrazine derivatives, ethyl acetoacetate, heterocyclic 1,2-ketones (ninhydrin, isatin, 5-bromoisatin) and cyclic 1,3-diketones (dimedone and 1,3-cyclohexanedine), examined in the presence of nano FeAl<jats:sub>2<\/jats:sub>O<jats:sub>4<\/jats:sub>-SiO<jats:sub>2<\/jats:sub>@[<jats:italic>DL<\/jats:italic>-Ala][NO<jats:sub>3<\/jats:sub>] nanohybrid in refluxing aqueous media, successfully. The multi-aspect characteristics of the nanohybrid which consist of magnetized inorganic and bioorganic parts, could be the reason of its special catalytic efficacy. The recovery and reusability of the FeAl<jats:sub>2<\/jats:sub>O<jats:sub>4<\/jats:sub>-SiO<jats:sub>2<\/jats:sub>@[<jats:italic>DL<\/jats:italic>-Ala][NO<jats:sub>3<\/jats:sub>] magnetized nanoparticles (MNPs) were performed in two runs without significant activity loss.<\/jats:p>","DOI":"10.1038\/s41598-024-66750-2","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T15:02:21Z","timestamp":1721055741000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Nano silicated-FeAl2O4 functionalized by DL-alaninium nitrate ionic liquid (FeAl2O4-SiO2@[DL-Ala][NO3]) as versatile promotor for aqua-mediated synthesis of spiro[chromenopyrazole-indene-triones and spiro[chromenopyrazole-indoline-diones"],"prefix":"10.1038","volume":"14","author":[{"given":"Fatemeh","family":"Molaei Yielzoleh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kobra","family":"Nikoofar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,15]]},"reference":[{"key":"66750_CR1","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1002\/cctc.201500854","volume":"8","author":"A Baeza","year":"2016","unstructured":"Baeza, A., Guillena, G. & Ram\u00f3n, D. 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