{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:18:08Z","timestamp":1792844288996,"version":"4.5.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["Unrestricted Departmental Grant"],"award-info":[{"award-number":["Unrestricted Departmental Grant"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["Unrestricted Departmental Grant"],"award-info":[{"award-number":["Unrestricted Departmental Grant"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["Unrestricted Departmental Grant"],"award-info":[{"award-number":["Unrestricted Departmental Grant"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["P30EY013810"],"award-info":[{"award-number":["P30EY013810"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["P30EY013810"],"award-info":[{"award-number":["P30EY013810"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["P30EY013810"],"award-info":[{"award-number":["P30EY013810"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research to Prevent Blindess\/American Academy of Ophthalmology, United States","award":["2020 Award for IRIS\u00ae Registry Research"],"award-info":[{"award-number":["2020 Award for IRIS\u00ae Registry Research"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-70148-5","type":"journal-article","created":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T03:24:24Z","timestamp":1723865064000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Predictors of intraocular pressure response and survival after phacoemulsification for glaucomatous eyes in the IRIS registry (Intelligent Research in Sight)"],"prefix":"10.1038","volume":"14","author":[{"given":"Adam L.","family":"Rothman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ta Chen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flora","family":"Lum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Vanner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"key":"70148_CR1","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1136\/bjophthalmol-2011-300539","volume":"96","author":"D Pascolini","year":"2012","unstructured":"Pascolini, D. & Mariotti, S. P. Global estimates of visual impairment: 2010. Br. J. Ophthalmol. 96, 614\u2013618 (2012).","journal-title":"Br. J. Ophthalmol."},{"key":"70148_CR2","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.ophtha.2020.10.022","volume":"128","author":"SJ Gedde","year":"2021","unstructured":"Gedde, S. J. et al. Primary open-angle glaucoma preferred practice pattern. Ophthalmology 128, 71\u2013150 (2021).","journal-title":"Ophthalmology"},{"key":"70148_CR3","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1001\/archophthalmol.2011.272","volume":"129","author":"G Huang","year":"2011","unstructured":"Huang, G. et al. Anterior chamber depth, iridocorneal angle width, and intraocular pressure changes after phacoemulsification: narrow vs open iridocorneal angles. Arch. Ophthalmol. 129, 1283\u20131290 (2011).","journal-title":"Arch. Ophthalmol."},{"key":"70148_CR4","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1016\/j.jcrs.2009.05.061","volume":"35","author":"BJ Poley","year":"2009","unstructured":"Poley, B. J., Lindstrom, R. L., Samuelson, T. W. & Schulze, R. Jr. Intraocular pressure reduction after phacoemulsification with intraocular lens implantation in glaucomatous and nonglaucomatous eyes: Evaluation of a causal relationship between the natural lens and open-angle glaucoma. J. Cataract. Refract. Surg. 35, 1946\u20131955 (2009).","journal-title":"J. Cataract. Refract. Surg."},{"key":"70148_CR5","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.ajo.2022.09.006","volume":"245","author":"AL Rothman","year":"2023","unstructured":"Rothman, A. L., Chang, T. C., Lum, F. & Vanner, E. A. Intraocular pressure changes following stand-alone phacoemulsification: an IRIS Registry analysis. Am. J. Ophthalmol. 245, 25\u201336 (2023).","journal-title":"Am. J. Ophthalmol."},{"key":"70148_CR6","doi-asserted-by":"publisher","first-page":"1826","DOI":"10.1016\/j.ophtha.2012.02.050","volume":"119","author":"SL Mansberger","year":"2012","unstructured":"Mansberger, S. L. et al. Reduction in intraocular pressure after cataract extraction: The ocular hypertension treatment study. Ophthalmology 119, 1826\u20131831 (2012).","journal-title":"Ophthalmology"},{"key":"70148_CR7","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/j.ophtha.2010.07.007","volume":"118","author":"TW Samuelson","year":"2011","unstructured":"Samuelson, T. W. et al. Randomized evaluation of the trabecular micro-bypass stent with phacoemulsification in patients with glaucoma and cataract. Ophthalmology 118, 459\u2013467 (2011).","journal-title":"Ophthalmology"},{"key":"70148_CR8","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1016\/j.ophtha.2019.03.006","volume":"126","author":"TW Samuelson","year":"2019","unstructured":"Samuelson, T. W. et al. Prospective, randomized, controlled pivotal trial of an ab interno implanted trabecular micro-bypass in primary open-angle glaucoma and cataract: two-year results. Ophthalmology 126, 811\u2013821 (2019).","journal-title":"Ophthalmology"},{"key":"70148_CR9","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.ophtha.2018.05.012","volume":"126","author":"TW Samuelson","year":"2019","unstructured":"Samuelson, T. W. et al. A Schlemm canal microstent for intraocular pressure reduction in primary open-angle glaucoma and cataract: The HORIZON study. Ophthalmology 126, 29\u201337 (2019).","journal-title":"Ophthalmology"},{"key":"70148_CR10","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1016\/j.ophtha.2015.03.021","volume":"122","author":"PP Chen","year":"2015","unstructured":"Chen, P. P. et al. The effect of phacoemulsification on intraocular pressure in glaucoma patients: A report by the American Academy of Ophthalmology. Ophthalmology 122, 1294\u20131307 (2015).","journal-title":"Ophthalmology"},{"key":"70148_CR11","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.ogla.2020.06.002","volume":"3","author":"SY Wang","year":"2020","unstructured":"Wang, S. Y. et al. Intraocular pressure changes after cataract surgery in patients with and without glaucoma: An informatics-based approach. Ophthalmol. Glaucoma. 3, 343\u2013349 (2020).","journal-title":"Ophthalmol. Glaucoma."},{"key":"70148_CR12","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1016\/j.jcrs.2014.12.054","volume":"41","author":"C Zetterstr\u00f6m","year":"2015","unstructured":"Zetterstr\u00f6m, C. et al. Changes in intraocular pressure after cataract surgery: Analysis of the Swedish national cataract register data. J. Cataract Refract. Surg. 41, 1725\u20131729 (2015).","journal-title":"J. Cataract Refract. Surg."},{"key":"70148_CR13","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.ajo.2013.08.023","volume":"157","author":"MA Slabaugh","year":"2014","unstructured":"Slabaugh, M. A., Bojikian, K. D., Moore, D. B. & Chen, P. P. The effect of phacoemulsification on intraocular pressure in medically controlled open-angle glaucoma patients. Am. J. Ophthalmol. 157, 26\u201331 (2014).","journal-title":"Am. J. Ophthalmol."},{"key":"70148_CR14","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1097\/IJG.0000000000000196","volume":"24","author":"S Moghimi","year":"2015","unstructured":"Moghimi, S. et al. Phacoemulsification versus combined phacoemulsification and viscogonioplasty in primary angle-closure glaucoma: a randomized clinical trial. J. Glaucoma. 24, 575\u2013582 (2015).","journal-title":"J. Glaucoma."},{"key":"70148_CR15","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.ajo.2013.02.003","volume":"156","author":"HS Yang","year":"2013","unstructured":"Yang, H. S., Lee, J. & Choi, S. Ocular biometric parameters associated with intraocular pressure reduction after cataract surgery in normal eyes. Am. J. Ophthalmol. 156, 89\u201394 (2013).","journal-title":"Am. J. Ophthalmol."},{"key":"70148_CR16","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1016\/S0886-3350(00)00753-7","volume":"27","author":"A Merkur","year":"2001","unstructured":"Merkur, A., Damji, K. F., Mintsioulis, G. & Hodge, W. G. Intraocular pressure decrease after phacoemulsification in patients with pseudoexfoliation syndrome. J. Cataract. Refract. Surg. 27, 528\u2013532 (2001).","journal-title":"J. Cataract. Refract. Surg."},{"key":"70148_CR17","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.ajo.2021.07.008","volume":"236","author":"SL Mansberger","year":"2022","unstructured":"Mansberger, S. L. et al. Cataract surgery lowers intraocular pressure and medication use in the medication group of the Ocular Hypertension Treatment Study. Am. J. Ophhthalmol. 236, 53\u201362 (2022).","journal-title":"Am. J. Ophhthalmol."},{"key":"70148_CR18","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1016\/j.ophtha.2022.02.021","volume":"129","author":"IIK Ahmed","year":"2022","unstructured":"Ahmed, I. I. K. et al. Long-term outcomes from the HORIZON randomized trial for a Schlemm\u2019s canal microstent in combination cataract and glaucoma surgery. Ophthalmology 129, 742\u2013751 (2022).","journal-title":"Ophthalmology"},{"key":"70148_CR19","doi-asserted-by":"publisher","first-page":"1834","DOI":"10.1016\/j.jcrs.2008.07.025","volume":"34","author":"BJ Shingleton","year":"2008","unstructured":"Shingleton, B. J. et al. Effect of phacoemulsification on intraocular pressure in eyes with pseudoexfoliation: single-surgeon series. J. Cataract. Refract. Surg. 34, 1834\u20131841 (2008).","journal-title":"J. Cataract. Refract. Surg."},{"key":"70148_CR20","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1097\/01.ijg.0000212294.31411.92","volume":"15","author":"BJ Shingleton","year":"2006","unstructured":"Shingleton, B. J., Pasternack, J. J., Hung, J. W. & O\u2019Donoghue, M. W. Three and five year changes in intraocular pressures after clear corneal phacoemulsification in open angle glaucoma patients, glaucoma suspects, and normal patients. J. Glaucoma. 15, 494\u2013498 (2006).","journal-title":"J. Glaucoma."},{"key":"70148_CR21","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/IIO.0000000000000481","volume":"63","author":"AL Rothman","year":"2023","unstructured":"Rothman, A. L. & Lee, R. H. Cataract extraction in glaucoma. Int. Ophthalmol. Clin. 63, 137\u2013152 (2023).","journal-title":"Int. Ophthalmol. Clin."},{"key":"70148_CR22","unstructured":"American Academy of Ophthalmology. IRIS Registry Data Analysis. Accessed May 9, 2023. https:\/\/www.aao.org\/iris-registry\/data-analysis\/requirements."},{"key":"70148_CR23","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/j.ophtha.2017.12.001","volume":"125","author":"MF Chiang","year":"2018","unstructured":"Chiang, M. F. et al. The 2016 American Academy of Ophthalmology IRIS Registry (Intelligent Research in Sight) database: Characteristics and methods. Ophthalmology 125, 1143\u20131148 (2018).","journal-title":"Ophthalmology"},{"issue":"7","key":"70148_CR24","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1016\/j.ophtha.2024.01.022","volume":"131","author":"AK Lidder","year":"2024","unstructured":"Lidder, A. K., Vanner, E. A., Chang, T. C., Lum, F. & Rothman, A. L. Intraocular pressure spike following stand-alone phacoemulsification in the IRIS Registry (Intelligent Research in Sight). Ophthalmology. https:\/\/doi.org\/10.1016\/j.ophtha.2024.01.022 (2024).","journal-title":"Ophthalmology"},{"key":"70148_CR25","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1097\/00061198-200310000-00007","volume":"12","author":"E Toker","year":"2003","unstructured":"Toker, E., Yenice, \u00d6. & Temel, A. Influence of serum levels of sex hormones on intraocular pressure in menopausal women. J. Glaucoma. 12, 436\u2013440 (2003).","journal-title":"J. Glaucoma."},{"key":"70148_CR26","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1007\/s10792-021-02002-w","volume":"42","author":"BC Saha","year":"2022","unstructured":"Saha, B. C. et al. Status of Rho kinase inhibitors in glaucoma therapeutics\u2014an overview. Int. Ophthalmology. 42, 281\u2013294 (2022).","journal-title":"Int. Ophthalmology."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70148-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70148-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70148-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T07:05:06Z","timestamp":1724137506000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70148-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,17]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["70148"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-70148-5","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,17]]},"assertion":[{"value":"28 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This research was funded in part by Research to Prevent Blindness (New York, NY, USA)\/American Academy of Ophthalmology (San Francisco, CA, USA) 2020 Award for IRIS Registry Research; NIH Center Core Grant (P30EY013810, Bethesda, MD, USA); Research to Prevent Blindness Unrestricted Grant (New York, NY, USA). The sponsor or funding organizations participated in the design of the study, conducting the research, data collection, data management, and review and approval of the manuscript. Dr. Lum is an employee of the American Academy of Ophthalmology. Dr Vanner is a stockholder for Greenlight Biosciences (Medford, MA, USA). Drs. Rothman, Chang, and Lum have no financial disclosures.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"19050"}}