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The pressure time integral (PTI) is an effective assessment that considers the time effect in various physical activities. We investigated the interactions between three different insole inner pressures (80, 160, and 240\u00a0mmHg) and two walking durations (10 and 20\u00a0min). The big toe (T1), first metatarsal head (M1), and second metatarsal head (M2) were investigated in 13 healthy participants. One-way analysis of variance (ANOVA) showed that the effects of each insole inner pressure significantly differed (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) with a 10\u00a0min walking duration. The PTI values resulting from 80\u00a0mmHg in M2 (38.4\u2009\u00b1\u20093.8, <jats:italic>P<\/jats:italic>\u2009=\u20090.002) and 160\u00a0mmHg in M1 (44.3\u2009\u00b1\u20094.3, <jats:italic>P<\/jats:italic>\u2009=\u20090.027) were lower than those from 240\u00a0mmHg. Additionally, the paired t test showed that the effects of each walking duration were also considerably different at 160\u00a0mmHg. The PTI at 10\u00a0min was lower than that at 20\u00a0min in M1 (44.31\u2009\u00b1\u20094.31, <jats:italic>P<\/jats:italic>\u2009=\u20090.015) and M2 (47.14\u2009\u00b1\u20095.27, <jats:italic>P<\/jats:italic>\u2009=\u20090.047). Thus, we suggest that walking with a pressure of 160\u00a0mmHg for 10\u00a0min has a lower risk of DFU.<\/jats:p>","DOI":"10.1038\/s41598-024-70312-x","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T12:02:27Z","timestamp":1724155347000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effect of different inner pressures of air insoles and walking durations on plantar pressure time integral"],"prefix":"10.1038","volume":"14","author":[{"given":"Gilang Titah","family":"Ramadhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahni","family":"Haris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yih-Kuen","family":"Jan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben-Yi","family":"Liau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Thong","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Cheng","family":"Tai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Wen","family":"Lung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,20]]},"reference":[{"issue":"2","key":"70312_CR1","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3390\/diabetology2020004","volume":"2","author":"S Alam","year":"2021","unstructured":"Alam, S. et al. 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