{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:28:48Z","timestamp":1792614528866,"version":"4.5.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-70896-4","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T20:24:56Z","timestamp":1724963096000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Medium optimization to improve growth and iron uptake by Bacillus tequilensis ASFS1 using fractional factorial designs"],"prefix":"10.1038","volume":"14","author":[{"given":"Naghmeh","family":"Satarzadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bagher","family":"Amirheidari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojtaba","family":"Shakibaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Forootanfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"70896_CR1","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1002\/jsid.1071","volume":"29","author":"P Kirya","year":"2021","unstructured":"Kirya, P. et al. Biomimicry of Blue Morpho butterfly wings: An introduction to nanotechnology through an interdisciplinary science education module. J. Soc. Inform. Disp. 29, 896\u2013915 (2021).","journal-title":"J. Soc. Inform. Disp."},{"issue":"4","key":"70896_CR2","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1007\/s10876-022-02356-w","volume":"34","author":"N Satarzadeh","year":"2022","unstructured":"Satarzadeh, N. et al. Facile microwave-assisted biosynthesis of arsenic nanoparticles and evaluation their antioxidant properties and cytotoxic effects: a preliminary in vitro study. J. Clust. Sci. 34(4), 1831\u20131839 (2022).","journal-title":"J. Clust. Sci."},{"key":"70896_CR3","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s13205-023-03476-4","volume":"13","author":"N Satarzadeh","year":"2023","unstructured":"Satarzadeh, N. et al. An insight into biofabrication of selenium nanostructures and their biomedical application. 3 Biotech 13, 79 (2023).","journal-title":"3 Biotech"},{"key":"70896_CR4","doi-asserted-by":"publisher","first-page":"21059","DOI":"10.1038\/s41598-022-25339-3","volume":"12","author":"NH Abdullah","year":"2022","unstructured":"Abdullah, N. H. Optimization of magnetic nano-iron production by Aspergillus flavipes MN956655. 1 using response surface methodology and evaluation of their dye decolorizing and antifungal activities. Sci. Rep. 12, 21059 (2022).","journal-title":"Sci. Rep."},{"key":"70896_CR5","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.arabjc.2017.05.011","volume":"12","author":"I Khan","year":"2019","unstructured":"Khan, I., Saeed, K. & Khan, I. Nanoparticles: Properties, applications and toxicities. Arab. J. Chem. 12, 908\u2013931 (2019).","journal-title":"Arab. J. Chem."},{"key":"70896_CR6","doi-asserted-by":"publisher","first-page":"11301","DOI":"10.3390\/app112311301","volume":"11","author":"MD Nguyen","year":"2021","unstructured":"Nguyen, M. D., Tran, H.-V., Xu, S. & Lee, T. R. J. A. S. Fe3O4 nanoparticles: Structures, synthesis, magnetic properties, surface functionalization, and emerging applications. Appl. Sci. 11, 11301 (2021).","journal-title":"Appl. Sci."},{"key":"70896_CR7","doi-asserted-by":"publisher","first-page":"16819","DOI":"10.1039\/c1jm11845e","volume":"21","author":"S Singamaneni","year":"2011","unstructured":"Singamaneni, S., Bliznyuk, V. N., Binek, C. & Tsymbal, E. Y. Magnetic nanoparticles: recent advances in synthesis, self-assembly and applications. J. Mater. Chem. 21, 16819\u201316845 (2011).","journal-title":"J. Mater. Chem."},{"key":"70896_CR8","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.pmatsci.2018.03.003","volume":"95","author":"D Lisjak","year":"2018","unstructured":"Lisjak, D. & Mertelj, A. Anisotropic magnetic nanoparticles: A review of their properties, syntheses and potential applications. Progr. Mater. Sci. 95, 286\u2013328 (2018).","journal-title":"Progr. Mater. Sci."},{"key":"70896_CR9","doi-asserted-by":"publisher","first-page":"8130","DOI":"10.3390\/s91008130","volume":"9","author":"I Koh","year":"2009","unstructured":"Koh, I. & Josephson, L. Magnetic nanoparticle sensors. Sensors 9, 8130\u20138145 (2009).","journal-title":"Sensors"},{"key":"70896_CR10","doi-asserted-by":"publisher","first-page":"2300","DOI":"10.3390\/s17102300","volume":"17","author":"Y-T Chen","year":"2017","unstructured":"Chen, Y.-T., Kolhatkar, A. G., Zenasni, O., Xu, S. & Lee, T. R. J. S. Biosensing using magnetic particle detection techniques. Sensors 17, 2300 (2017).","journal-title":"Sensors"},{"key":"70896_CR11","doi-asserted-by":"publisher","first-page":"2530","DOI":"10.1016\/j.ijbiomac.2018.09.025","volume":"120","author":"M Bilal","year":"2018","unstructured":"Bilal, M., Zhao, Y., Rasheed, T. & Iqbal, H. M. N. Magnetic nanoparticles as versatile carriers for enzymes immobilization: A review. Int. J. Biol. Macromol. 120, 2530\u20132544 (2018).","journal-title":"Int. J. Biol. Macromol."},{"key":"70896_CR12","doi-asserted-by":"publisher","first-page":"9560","DOI":"10.1021\/acsanm.0c02048","volume":"3","author":"K Wu","year":"2020","unstructured":"Wu, K. et al. Magnetic-nanosensor-based virus and pathogen detection strategies before and during COVID-19. ACS Appl. Nano Mater. 3, 9560\u20139580 (2020).","journal-title":"ACS Appl. Nano Mater."},{"key":"70896_CR13","doi-asserted-by":"publisher","first-page":"2064","DOI":"10.1021\/cr068445e","volume":"108","author":"S Laurent","year":"2008","unstructured":"Laurent, S. et al. Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem. Rev. 108, 2064\u20132110 (2008).","journal-title":"Chem. Rev."},{"key":"70896_CR14","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1002\/smll.201202111","volume":"9","author":"D Ling","year":"2013","unstructured":"Ling, D. & Hyeon, T. J. S. Chemical design of biocompatible iron oxide nanoparticles for medical applications. Small 9, 1450\u20131466 (2013).","journal-title":"Small"},{"key":"70896_CR15","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.1007\/s11095-016-1958-5","volume":"33","author":"D Bobo","year":"2016","unstructured":"Bobo, D., Robinson, K. J., Islam, J., Thurecht, K. J. & Corrie, S. R. Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date. Pharmaceut. Res. 33, 2373\u20132387 (2016).","journal-title":"Pharmaceut. Res."},{"key":"70896_CR16","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.pcrysgrow.2008.08.003","volume":"55","author":"AS Teja","year":"2009","unstructured":"Teja, A. S. & Koh, P.-Y. Synthesis, properties, and applications of magnetic iron oxide nanoparticles. Prog. Cryst. Growth Charact. Mater. 55, 22\u201345 (2009).","journal-title":"Prog. Cryst. Growth Charact. Mater."},{"key":"70896_CR17","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1016\/j.jsps.2014.11.013","volume":"24","author":"P Kuppusamy","year":"2016","unstructured":"Kuppusamy, P., Yusoff, M. M., Maniam, G. P. & Govindan, N. Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications\u2013an updated report. Saudi Pharmaceut. J. 24, 473\u2013484 (2016).","journal-title":"Saudi Pharmaceut. J."},{"key":"70896_CR18","doi-asserted-by":"publisher","first-page":"566","DOI":"10.34172\/apb.2020.067","volume":"10","author":"B Bhardwaj","year":"2020","unstructured":"Bhardwaj, B., Singh, P., Kumar, A., Kumar, S. & Budhwar, V. J. A. P. B. Eco-friendly greener synthesis of nanoparticles. Adv. Pharmaceut. Bull. 10, 566 (2020).","journal-title":"Adv. Pharmaceut. Bull."},{"key":"70896_CR19","doi-asserted-by":"publisher","first-page":"111967","DOI":"10.1016\/j.envres.2021.111967","volume":"204","author":"SF Ahmed","year":"2022","unstructured":"Ahmed, S. F. et al. Green approaches in synthesising nanomaterials for environmental nanobioremediation: Technological advancements, applications, benefits and challenges. Environ. Res. 204, 111967 (2022).","journal-title":"Environ. Res."},{"key":"70896_CR20","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/j.tibtech.2016.02.006","volume":"34","author":"P Singh","year":"2016","unstructured":"Singh, P., Kim, Y.-J., Zhang, D. & Yang, D.-C. Biological synthesis of nanoparticles from plants and microorganisms. Trends Biotechnol. 34, 588\u2013599 (2016).","journal-title":"Trends Biotechnol."},{"key":"70896_CR21","doi-asserted-by":"publisher","first-page":"122880","DOI":"10.1016\/j.jclepro.2020.122880","volume":"272","author":"A Rana","year":"2020","unstructured":"Rana, A., Yadav, K. & Jagadevan, S. A comprehensive review on green synthesis of nature-inspired metal nanoparticles: Mechanism, application and toxicity. J. Clean. Prod. 272, 122880 (2020).","journal-title":"J. Clean. Prod."},{"key":"70896_CR22","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3389\/fbioe.2020.00016","volume":"8","author":"C Berny","year":"2020","unstructured":"Berny, C. et al. A method for producing highly pure magnetosomes in large quantity for medical applications using Magnetospirillum gryphiswaldense MSR-1 magnetotactic bacteria amplified in minimal growth media. Front. Bioeng. Biotechnol. 8, 16 (2020).","journal-title":"Front. Bioeng. Biotechnol."},{"key":"70896_CR23","doi-asserted-by":"publisher","first-page":"010","DOI":"10.1093\/jimb\/kuae010","volume":"51","author":"S Moon","year":"2024","unstructured":"Moon, S., Saboe, A. & Smanski, M. J. Using design of experiments to guide genetic optimization of engineered metabolic pathways. J. Ind. Microbiol. Biotechnol. 51, 010 (2024).","journal-title":"J. Ind. Microbiol. Biotechnol."},{"key":"70896_CR24","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.1038\/s41598-018-37171-9","volume":"9","author":"K-Y Khaw","year":"2019","unstructured":"Khaw, K.-Y. et al. Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice. Sci. Rep. 9, 1716 (2019).","journal-title":"Sci. Rep."},{"key":"70896_CR25","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1021\/op500169m","volume":"19","author":"SA Weissman","year":"2015","unstructured":"Weissman, S. A. & Anderson, N. G. Design of experiments (DoE) and process optimization. A review of recent publications. Org. Process Res. Dev. 19, 1605\u20131633 (2015).","journal-title":"Org. Process Res. Dev."},{"key":"70896_CR26","doi-asserted-by":"publisher","first-page":"111298","DOI":"10.1016\/j.enbuild.2021.111298","volume":"250","author":"A Jankovic","year":"2021","unstructured":"Jankovic, A., Chaudhary, G. & Goia, F. Designing the design of experiments (DOE)\u2013An investigation on the influence of different factorial designs on the characterization of complex systems. Energy Build. 250, 111298 (2021).","journal-title":"Energy Build."},{"key":"70896_CR27","doi-asserted-by":"publisher","DOI":"10.1002\/jobm.202400153","author":"N Satarzadeh","year":"2024","unstructured":"Satarzadeh, N., Shakibaie, M., Forootanfar, H. & Amirheidari, B. Purification, characterization, and assessment of anticancer activity of iron oxide nanoparticles biosynthesized by novel thermophilic Bacillus tequilensis ASFS1. J. Basic Microbiol. https:\/\/doi.org\/10.1002\/jobm.202400153 (2024).","journal-title":"J. Basic Microbiol."},{"key":"70896_CR28","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.actbio.2020.07.042","volume":"120","author":"S Rosenfeldt","year":"2021","unstructured":"Rosenfeldt, S. et al. Towards standardized purification of bacterial magnetic nanoparticles for future in vivo applications. Acta Biomater. 120, 293\u2013303 (2021).","journal-title":"Acta Biomater."},{"key":"70896_CR29","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1007\/s00253-012-4199-5","volume":"96","author":"E Alphand\u00e9ry","year":"2012","unstructured":"Alphand\u00e9ry, E., Amor, M., Guyot, F. & Chebbi, I. The effect of iron-chelating agents on Magnetospirillum magneticum strain AMB-1: Stimulated growth and magnetosome production and improved magnetosome heating properties. Appl. Microbiol. Biotechnol. 96, 663\u2013670. https:\/\/doi.org\/10.1007\/s00253-012-4199-5 (2012).","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"70896_CR30","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1385\/ABAB:91-93:1-9:155","volume":"91","author":"C-D Yang","year":"2001","unstructured":"Yang, C.-D. et al. Synthesis of bacterial magnetic particles during cell cycle of Magnetospirillum magneticum AMB-1. Appl. Biochem. Biotechnol. 91, 155\u2013160 (2001).","journal-title":"Appl. Biochem. Biotechnol."},{"key":"70896_CR31","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1007\/s00253-002-1219-x","volume":"61","author":"U Heyen","year":"2003","unstructured":"Heyen, U. & Sch\u00fcler, D. Growth and magnetosome formation by microaerophilic Magnetospirillum strains in an oxygen-controlled fermentor. Appl. Microbiol. Biotechnol. 61, 536\u2013544 (2003).","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"70896_CR32","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1080\/01490451.2011.594146","volume":"28","author":"C Moisescu","year":"2011","unstructured":"Moisescu, C., Bonneville, S., Staniland, S., Ardelean, I. & Benning, L. G. Iron uptake kinetics and magnetosome formation by Magnetospirillum gryphiswaldense as a function of pH, temperature and dissolved iron availability. Geomicrobiol. J. 28, 590\u2013600 (2011).","journal-title":"Geomicrobiol. J."},{"key":"70896_CR33","first-page":"1503","volume":"7","author":"H Kabary","year":"2018","unstructured":"Kabary, H., Eida, M. F., Attia, M., Awad, N. & Easa, S. M. Optimization of growth and Fe uptake by Pseudomonas aeruginosa Kb1 for biosynthesis of magnetic nanoparticles. Middle East J. 7, 1503\u20131513 (2018).","journal-title":"Middle East J."},{"key":"70896_CR34","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/j.msec.2015.10.060","volume":"59","author":"L Yan","year":"2016","unstructured":"Yan, L. et al. Optimization of magnetosome production by Acidithiobacillus ferrooxidans using desirability function approach. Mater. Sci. Eng. C 59, 731\u2013739 (2016).","journal-title":"Mater. Sci. Eng. C"},{"key":"70896_CR35","doi-asserted-by":"publisher","first-page":"6142","DOI":"10.5897\/AJMR12.157","volume":"6","author":"S Zhang","year":"2012","unstructured":"Zhang, S., Yan, L., Li, H. & Liu, H. J. Optimal conditions for growth and magnetosome formation of Acidithiobacillus ferrooxidans. Afr. J. Microbiol. Res. 6, 6142\u20136151 (2012).","journal-title":"Afr. J. Microbiol. Res."},{"key":"70896_CR36","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/S0141-0229(01)00343-X","volume":"29","author":"C-D Yang","year":"2001","unstructured":"Yang, C.-D., Takeyama, H., Tanaka, T., Matsunaga, T. J. E. & Technology, M. Effects of growth medium composition, iron sources and atmospheric oxygen concentrations on production of luciferase-bacterial magnetic particle complex by a recombinant Magnetospirillum magneticum AMB-1. Enzyme Microb. Technol. 29, 13\u201319 (2001).","journal-title":"Enzyme Microb. Technol."},{"key":"70896_CR37","first-page":"1","volume":"19","author":"A Basit","year":"2001","unstructured":"Basit, A., Wang, J., Guo, F., Niu, W. & Jiang, W. Improved methods for mass production of magnetosomes and applications: A review. Microb. Cell Fact. 19, 1\u201311 (2001).","journal-title":"Microb. Cell Fact."},{"key":"70896_CR38","doi-asserted-by":"publisher","DOI":"10.1201\/b18479","volume-title":"DOE simplified: practical tools for effective experimentation","author":"MJ Anderson","year":"2017","unstructured":"Anderson, M. J. & Whitcomb, P. J. DOE simplified: practical tools for effective experimentation (CRC Press, 2017)."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70896-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70896-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70896-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T20:29:51Z","timestamp":1724963391000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-70896-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,29]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["70896"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-70896-4","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,29]]},"assertion":[{"value":"8 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"20141"}}