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Seventy-two overweight participants with symptomatic knee OA were randomly assigned to WB-EMS (n\u2009=\u200936) or a usual care group (UCG, n\u2009=\u200936). For seven months, the WB-EMS group received three times per fortnight a WB-EMS training, while the UCG was prescribed six-times physiotherapeutic treatments. We observed significant effects for the primary outcome \u201cpain\u201d, as determined by the Knee injury and Osteoarthritis Outcome Score (KOOS), with more favourable changes in the WB-EMS group vs UCG (between-group difference 9.0 points, 95%CI 2.9\u201315.1,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.004). Secondary outcomes, including the other KOOS subscales (symptoms, function in daily living, function in sports\/recreational activities and quality of life), 7\u00a0day pain diary, hip\/leg extensor strength and lower limb function (30s sit-to-stand test), were also statistically significant in favour of the WB-EMS group. Overall, WB-EMS was found to be effective in relieving knee pain symptoms and improving physical function in individuals with symptomatic knee OA compared to usual care treatment. WB-EMS could be used as an alternative\u00a0therapy in the management of knee OA; particularly for patients that cannot be motivated for conventional training.\n                  <\/jats:p>","DOI":"10.1038\/s41598-024-71552-7","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T04:05:51Z","timestamp":1725595551000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Effectiveness of whole-body electromyostimulation on knee pain and physical function in knee osteoarthritis: a randomized controlled trial"],"prefix":"10.1038","volume":"14","author":[{"given":"Stephanie","family":"Kast","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Kemmler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank W.","family":"Roemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Kohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam G.","family":"Culvenor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Mobasheri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Uder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"von Stengel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"71552_CR1","doi-asserted-by":"publisher","first-page":"1568","DOI":"10.1001\/jama.2023.19675","volume":"330","author":"V Duong","year":"2023","unstructured":"Duong, V., Oo, W. 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