{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:06:21Z","timestamp":1772136381314,"version":"3.50.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T00:00:00Z","timestamp":1725926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T00:00:00Z","timestamp":1725926400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Medical Health Science and Technology Program of Shandong Province","award":["202309020311"],"award-info":[{"award-number":["202309020311"]}]},{"name":"Postdoctoral Research Fund of Jining","award":["JYFY362641"],"award-info":[{"award-number":["JYFY362641"]}]},{"name":"Municipal Health Commission Scientific Research Project Program of Shanghai","award":["202240083"],"award-info":[{"award-number":["202240083"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-72046-2","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T10:02:46Z","timestamp":1725962566000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ultrasound based radiomics model for assessment of placental function in pregnancies with preeclampsia"],"prefix":"10.1038","volume":"14","author":[{"given":"Hongshuang","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yicong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaochun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Ban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunyun","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,10]]},"reference":[{"key":"72046_CR1","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/s0140-6736(10)60279-6","volume":"376","author":"EA Steegers","year":"2010","unstructured":"Steegers, E. A., von Dadelszen, P., Duvekot, J. J. & Pijnenborg, R. Pre-eclampsia. Lancet 376, 631\u2013644. https:\/\/doi.org\/10.1016\/s0140-6736(10)60279-6 (2010).","journal-title":"Lancet"},{"key":"72046_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/aog.0000000000003018","volume":"133","author":"ACOG Practice Bulletin No. 202","year":"2019","unstructured":"ACOG Practice Bulletin No. 202. Gestational hypertension and preeclampsia. Obstet. Gynecol. 133, 1. https:\/\/doi.org\/10.1097\/aog.0000000000003018 (2019).","journal-title":"Obstet. Gynecol."},{"key":"72046_CR3","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/s0140-6736(20)32335-7","volume":"398","author":"LC Chappell","year":"2021","unstructured":"Chappell, L. C., Cluver, C. A., Kingdom, J. & Tong, S. Pre-eclampsia. Lancet 398, 341\u2013354. https:\/\/doi.org\/10.1016\/s0140-6736(20)32335-7 (2021).","journal-title":"Lancet"},{"key":"72046_CR4","doi-asserted-by":"publisher","first-page":"S786","DOI":"10.1016\/j.ajog.2021.12.001","volume":"226","author":"O Erez","year":"2022","unstructured":"Erez, O. et al. Preeclampsia and eclampsia: The conceptual evolution of a syndrome. Am. J. Obstet. Gynecol. 226, S786-s803. https:\/\/doi.org\/10.1016\/j.ajog.2021.12.001 (2022).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"72046_CR5","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1055\/s-0041-1728823","volume":"40","author":"Z Hoodbhoy","year":"2023","unstructured":"Hoodbhoy, Z. et al. The impact of maternal preeclampsia and hyperglycemia on the cardiovascular health of the offspring: A systematic review and meta-analysis. Am. J. Perinatol. 40, 363\u2013374. https:\/\/doi.org\/10.1055\/s-0041-1728823 (2023).","journal-title":"Am. J. Perinatol."},{"key":"72046_CR6","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1038\/s41581-019-0119-6","volume":"15","author":"EA Phipps","year":"2019","unstructured":"Phipps, E. A., Thadhani, R., Benzing, T. & Karumanchi, S. A. Pre-eclampsia: Pathogenesis, novel diagnostics and therapies. Nat. Rev. Nephrol. 15, 275\u2013289. https:\/\/doi.org\/10.1038\/s41581-019-0119-6 (2019).","journal-title":"Nat. Rev. Nephrol."},{"key":"72046_CR7","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1097\/aog.0000000000002264","volume":"130","author":"E Wright","year":"2017","unstructured":"Wright, E. et al. Maternal vascular malperfusion and adverse perinatal outcomes in low-risk nulliparous women. Obstet. Gynecol. 130, 1112\u20131120. https:\/\/doi.org\/10.1097\/aog.0000000000002264 (2017).","journal-title":"Obstet. Gynecol."},{"key":"72046_CR8","doi-asserted-by":"publisher","first-page":"S844","DOI":"10.1016\/j.ajog.2021.11.1356","volume":"226","author":"E Jung","year":"2022","unstructured":"Jung, E. et al. The etiology of preeclampsia. Am. J. Obstet. Gynecol. 226, S844-s866. https:\/\/doi.org\/10.1016\/j.ajog.2021.11.1356 (2022).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"72046_CR9","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.ajog.2010.08.009","volume":"204","author":"I Brosens","year":"2011","unstructured":"Brosens, I., Pijnenborg, R., Vercruysse, L. & Romero, R. The, \u201cGreat Obstetrical Syndromes\u201d are associated with disorders of deep placentation. Am. J. Obstet. Gynecol. 204, 193\u2013201. https:\/\/doi.org\/10.1016\/j.ajog.2010.08.009 (2011).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"72046_CR10","doi-asserted-by":"publisher","DOI":"10.3390\/cells10113055","author":"MA Opichka","year":"2021","unstructured":"Opichka, M. A., Rappelt, M. W., Gutterman, D. D., Grobe, J. L. & McIntosh, J. J. Vascular dysfunction in preeclampsia. Cells https:\/\/doi.org\/10.3390\/cells10113055 (2021).","journal-title":"Cells"},{"key":"72046_CR11","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1002\/uog.17494","volume":"50","author":"ML Falco","year":"2017","unstructured":"Falco, M. L., Sivanathan, J., Laoreti, A., Thilaganathan, B. & Khalil, A. Placental histopathology associated with pre-eclampsia: Systematic review and meta-analysis. Ultrasound Obstet. Gynecol. 50, 295\u2013301. https:\/\/doi.org\/10.1002\/uog.17494 (2017).","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"72046_CR12","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1001\/jamacardio.2017.0283","volume":"2","author":"RM Hayward","year":"2017","unstructured":"Hayward, R. M., Foster, E. & Tseng, Z. H. Maternal and fetal outcomes of admission for delivery in women with congenital heart disease. JAMA Cardiol. 2, 664\u2013671. https:\/\/doi.org\/10.1001\/jamacardio.2017.0283 (2017).","journal-title":"JAMA Cardiol."},{"key":"72046_CR13","doi-asserted-by":"publisher","first-page":"S954","DOI":"10.1016\/j.ajog.2020.10.024","volume":"226","author":"K Melchiorre","year":"2022","unstructured":"Melchiorre, K., Giorgione, V. & Thilaganathan, B. The placenta and preeclampsia: Villain or victim?. Am. J. Obstet. Gynecol. 226, S954-s962. https:\/\/doi.org\/10.1016\/j.ajog.2020.10.024 (2022).","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"484","key":"72046_CR14","doi-asserted-by":"publisher","first-page":"e481","DOI":"10.1016\/j.ajog.2016.05.047","volume":"215","author":"MA Cain","year":"2016","unstructured":"Cain, M. A. et al. Pregnancy as a window to future health: Maternal placental syndromes and short-term cardiovascular outcomes. Am. J. Obstet. Gynecol. 215(484), e481-484.e414. https:\/\/doi.org\/10.1016\/j.ajog.2016.05.047 (2016).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"72046_CR15","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1136\/jcp.2008.055251","volume":"61","author":"NJ Sebire","year":"2008","unstructured":"Sebire, N. J. & Sepulveda, W. Correlation of placental pathology with prenatal ultrasound findings. J. Clin. Pathol. 61, 1276\u20131284. https:\/\/doi.org\/10.1136\/jcp.2008.055251 (2008).","journal-title":"J. Clin. Pathol."},{"key":"72046_CR16","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s13244-020-00887-2","volume":"11","author":"JE van Timmeren","year":"2020","unstructured":"van Timmeren, J. E., Cester, D., Tanadini-Lang, S., Alkadhi, H. & Baessler, B. Radiomics in medical imaging-\u201chow-to\u201d guide and critical reflection. Insights Imaging 11, 91. https:\/\/doi.org\/10.1186\/s13244-020-00887-2 (2020).","journal-title":"Insights Imaging"},{"key":"72046_CR17","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1002\/med.21846","volume":"42","author":"J Guiot","year":"2022","unstructured":"Guiot, J. et al. A review in radiomics: Making personalized medicine a reality via routine imaging. Med. Res. Rev. 42, 426\u2013440. https:\/\/doi.org\/10.1002\/med.21846 (2022).","journal-title":"Med. Res. Rev."},{"key":"72046_CR18","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1016\/j.ultrasmedbio.2022.03.007","volume":"48","author":"L Zhu","year":"2022","unstructured":"Zhu, L. et al. Machine learning-based ultrasound radiomics for evaluating the function of transplanted kidneys. Ultrasound Med. Biol. 48, 1441\u20131452. https:\/\/doi.org\/10.1016\/j.ultrasmedbio.2022.03.007 (2022).","journal-title":"Ultrasound Med. Biol."},{"key":"72046_CR19","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1002\/uog.24805","volume":"60","author":"F Moro","year":"2022","unstructured":"Moro, F. et al. Developing and validating ultrasound-based radiomics models for predicting high-risk endometrial cancer. Ultrasound Obstet. Gynecol. 60, 256\u2013268. https:\/\/doi.org\/10.1002\/uog.24805 (2022).","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"72046_CR20","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1038\/nrclinonc.2017.141","volume":"14","author":"P Lambin","year":"2017","unstructured":"Lambin, P. et al. Radiomics: The bridge between medical imaging and personalized medicine. Nat. Rev. Clin. Oncol. 14, 749\u2013762. https:\/\/doi.org\/10.1038\/nrclinonc.2017.141 (2017).","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"72046_CR21","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1177\/0192623318755135","volume":"46","author":"PL Charest","year":"2018","unstructured":"Charest, P. L. et al. Histomorphologic analysis of the late-term rat fetus and placenta. Toxicol. Pathol. 46, 158\u2013168. https:\/\/doi.org\/10.1177\/0192623318755135 (2018).","journal-title":"Toxicol. Pathol."},{"key":"72046_CR22","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1038\/s41371-021-00637-x","volume":"36","author":"K Chau","year":"2022","unstructured":"Chau, K., Welsh, M., Makris, A. & Hennessy, A. Progress in preeclampsia: The contribution of animal models. J. Hum. Hypertens 36, 705\u2013710. https:\/\/doi.org\/10.1038\/s41371-021-00637-x (2022).","journal-title":"J. Hum. Hypertens"},{"key":"72046_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms20174246","volume":"20","author":"T Tomimatsu","year":"2019","unstructured":"Tomimatsu, T. et al. Preeclampsia: Maternal systemic vascular disorder caused by generalized endothelial dysfunction due to placental antiangiogenic factors. Int. J. Mol. Sci. 20, 1. https:\/\/doi.org\/10.3390\/ijms20174246 (2019).","journal-title":"Int. J. Mol. Sci."},{"key":"72046_CR24","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s12272-020-01220-7","volume":"43","author":"J Huang","year":"2020","unstructured":"Huang, J. et al. Mangiferin ameliorates placental oxidative stress and activates PI3K\/Akt\/mTOR pathway in mouse model of preeclampsia. Arch. Pharm. Res. 43, 233\u2013241. https:\/\/doi.org\/10.1007\/s12272-020-01220-7 (2020).","journal-title":"Arch. Pharm. Res."},{"key":"72046_CR25","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/laban.1272","volume":"46","author":"B Lipt\u00e1k","year":"2017","unstructured":"Lipt\u00e1k, B., Kaprinay, B. & G\u00e1sp\u00e1rov\u00e1, Z. A rat-friendly modification of the non-invasive tail-cuff to record blood pressure. Lab. Anim. (N. Y.) 46, 251\u2013253. https:\/\/doi.org\/10.1038\/laban.1272 (2017).","journal-title":"Lab. Anim. (N. Y.)"},{"key":"72046_CR26","doi-asserted-by":"crossref","unstructured":"Akusok, A., Eirola, E., Bjork, K. M. & Lendasse, A. In International Conference on Extreme Learning Machine (ELM). 181\u2013185 (2019).","DOI":"10.1007\/978-3-030-01520-6_16"},{"key":"72046_CR27","doi-asserted-by":"publisher","first-page":"19009","DOI":"10.3390\/ijms160819009","volume":"16","author":"I Herraiz","year":"2015","unstructured":"Herraiz, I. et al. Angiogenesis-related biomarkers (sFlt-1\/PLGF) in the prediction and diagnosis of placental dysfunction: An approach for clinical integration. Int. J. Mol. Sci. 16, 19009\u201319026. https:\/\/doi.org\/10.3390\/ijms160819009 (2015).","journal-title":"Int. J. Mol. Sci."},{"key":"72046_CR28","doi-asserted-by":"publisher","first-page":"Cd011202","DOI":"10.1002\/14651858.CD011202.pub2","volume":"2015","author":"AE Heazell","year":"2015","unstructured":"Heazell, A. E., Whitworth, M., Duley, L. & Thornton, J. G. Use of biochemical tests of placental function for improving pregnancy outcome. Cochrane Database Syst. Rev. 2015, Cd011202. https:\/\/doi.org\/10.1002\/14651858.CD011202.pub2 (2015).","journal-title":"Cochrane Database Syst. Rev."},{"key":"72046_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/math10010029","author":"JX Leon-Medina","year":"2022","unstructured":"Leon-Medina, J. X., Pares, N., Anaya, M., Tibaduiza, D. A. & Pozo, F. Data classification methodology for electronic noses using uniform manifold approximation and projection and extreme learning machine. Mathematics https:\/\/doi.org\/10.3390\/math10010029 (2022).","journal-title":"Mathematics"},{"key":"72046_CR30","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1038\/s42256-019-0138-9","volume":"2","author":"SM Lundberg","year":"2020","unstructured":"Lundberg, S. M. et al. From local explanations to global understanding with explainable AI for trees. Nat. Mach. Intell. 2, 56\u201367. https:\/\/doi.org\/10.1038\/s42256-019-0138-9 (2020).","journal-title":"Nat. Mach. Intell."},{"key":"72046_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1293\/tox.2018-0042","volume":"32","author":"S Furukawa","year":"2019","unstructured":"Furukawa, S., Tsuji, N. & Sugiyama, A. Morphology and physiology of rat placenta for toxicological evaluation. J. Toxicol. Pathol. 32, 1\u201317. https:\/\/doi.org\/10.1293\/tox.2018-0042 (2019).","journal-title":"J. Toxicol. Pathol."},{"key":"72046_CR32","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.preghy.2022.12.003","volume":"31","author":"H Sun","year":"2023","unstructured":"Sun, H., Jiao, J., Ren, Y., Guo, Y. & Wang, Y. Multimodal fusion model for classifying placenta ultrasound imaging in pregnancies with hypertension disorders. Pregnancy Hypertens 31, 46\u201353. https:\/\/doi.org\/10.1016\/j.preghy.2022.12.003 (2023).","journal-title":"Pregnancy Hypertens"},{"key":"72046_CR33","doi-asserted-by":"publisher","first-page":"5587","DOI":"10.1080\/14767058.2021.1887847","volume":"35","author":"K Gupta","year":"2022","unstructured":"Gupta, K. et al. Ultrasound placental image texture analysis using artificial intelligence to predict hypertension in pregnancy. J. Matern. Fetal. Neonatal. Med. 35, 5587\u20135594. https:\/\/doi.org\/10.1080\/14767058.2021.1887847 (2022).","journal-title":"J. Matern. Fetal. Neonatal. Med."},{"key":"72046_CR34","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s43032-020-00287-3","volume":"28","author":"N Gonen","year":"2021","unstructured":"Gonen, N. et al. Placental histopathology and pregnancy outcomes in \u201cearly\u201d vs. \u201clate\u201d placental abruption. Reprod. Sci. 28, 351\u2013360. https:\/\/doi.org\/10.1007\/s43032-020-00287-3 (2021).","journal-title":"Reprod. Sci."},{"key":"72046_CR35","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.placenta.2014.02.012","volume":"35","author":"AE Guttmacher","year":"2014","unstructured":"Guttmacher, A. E., Maddox, Y. T. & Spong, C. Y. The human placenta project: Placental structure, development, and function in real time. Placenta 35, 303\u2013304. https:\/\/doi.org\/10.1016\/j.placenta.2014.02.012 (2014).","journal-title":"Placenta"},{"key":"72046_CR36","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.placenta.2019.03.016","volume":"80","author":"JV Ilekis","year":"2019","unstructured":"Ilekis, J. V. et al. The Placental Atlas Tool (PAT): A collaborative research and discovery platform for the placental research community. Placenta 80, 42\u201348. https:\/\/doi.org\/10.1016\/j.placenta.2019.03.016 (2019).","journal-title":"Placenta"},{"key":"72046_CR37","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222011261","author":"AC Palei","year":"2021","unstructured":"Palei, A. C., Granger, J. P. & Spradley, F. T. Placental ischemia says \u201cNO\u201d to proper NOS-mediated control of vascular tone and blood pressure in preeclampsia. Int. J. Mol. Sci. https:\/\/doi.org\/10.3390\/ijms222011261 (2021).","journal-title":"Int. J. Mol. Sci."},{"key":"72046_CR38","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22168622","author":"X Hu","year":"2021","unstructured":"Hu, X. & Zhang, L. Uteroplacental circulation in normal pregnancy and preeclampsia: Functional adaptation and maladaptation. Int. J. Mol. Sci. https:\/\/doi.org\/10.3390\/ijms22168622 (2021).","journal-title":"Int. J. Mol. Sci."},{"key":"72046_CR39","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1055\/a-1184-8388","volume":"40","author":"L Skeith","year":"2020","unstructured":"Skeith, L., Blondon, M. & \u00c1inle, F. N. Understanding and preventing placenta-mediated pregnancy complications. Hamostaseologie 40, 356\u2013363. https:\/\/doi.org\/10.1055\/a-1184-8388 (2020).","journal-title":"Hamostaseologie"},{"key":"72046_CR40","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1111\/febs.15745","volume":"289","author":"M Hu","year":"2022","unstructured":"Hu, M., Li, J., Baker, P. N. & Tong, C. Revisiting preeclampsia: A metabolic disorder of the placenta. Febs J 289, 336\u2013354. https:\/\/doi.org\/10.1111\/febs.15745 (2022).","journal-title":"Febs J"},{"key":"72046_CR41","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1002\/uog.26032","volume":"61","author":"H Stepan","year":"2023","unstructured":"Stepan, H. et al. Clinical utility of sFlt-1 and PlGF in screening, prediction, diagnosis and monitoring of pre-eclampsia and fetal growth restriction. Ultrasound Obstet. Gynecol. 61, 168\u2013180. https:\/\/doi.org\/10.1002\/uog.26032 (2023).","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"72046_CR42","doi-asserted-by":"publisher","first-page":"1420","DOI":"10.1016\/j.drudis.2021.03.001","volume":"26","author":"X Feng","year":"2021","unstructured":"Feng, X. et al. New views on endothelial dysfunction in gestational hypertension and potential therapy targets. Drug. Discov. Today 26, 1420\u20131436. https:\/\/doi.org\/10.1016\/j.drudis.2021.03.001 (2021).","journal-title":"Drug. Discov. Today"},{"key":"72046_CR43","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1161\/hypertensionaha.119.13763","volume":"75","author":"H Stepan","year":"2020","unstructured":"Stepan, H., Hund, M. & Andraczek, T. Combining biomarkers to predict pregnancy complications and redefine preeclampsia: The angiogenic-placental syndrome. Hypertension 75, 918\u2013926. https:\/\/doi.org\/10.1161\/hypertensionaha.119.13763 (2020).","journal-title":"Hypertension"}],"updated-by":[{"DOI":"10.1038\/s41598-024-81772-6","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000}}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-72046-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-72046-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-72046-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T11:04:20Z","timestamp":1734347060000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-72046-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,10]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["72046"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-72046-2","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3781498\/v1","asserted-by":"object"}]},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,10]]},"assertion":[{"value":"20 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2024","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1038\/s41598-024-81772-6","URL":"https:\/\/doi.org\/10.1038\/s41598-024-81772-6","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"21123"}}