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Eighty-four recruited participants were randomly allocated into four groups (21 patients per group). One posterior Bulk-fill proximal restoration was performed for each participant according to the preheating cycles where in group I; teeth were restored with non-heated resin composite, group II: One preheating cycle of composite syringe was performed prior restoration, and group III: five preheating cycles while for group IV: Ten preheating cycles were performed. These restorations were clinically evaluated at 6, 12, 18 and 24 months. Statistical analysis was performed using one way ANOVA, with set p-value\u2009&lt;\u20090.05. The results revealed that there was perfect agreement between both observers and observations WK (95% CI) [0.908 (0.780:1.000)] and [0.940 (0.824:1.000)], respectively. All restorations showed acceptable clinical performance with alpha and bravo scores. No replacement was required for any restoration. No statistically significant differences were detected between the control and intervention groups across all parameters during the various evaluation stages. It could be concluded that the clinical performance of ten cycles of repeated preheated bulk fill resin composite was equivalent to that of non-preheating resin composites after 24 months follow-up period, with great improvement in manipulation. Preheating of resin composite could be performed up to ten cycles prior to placement without any clinical adverse consequences on the performance of the restoration.<\/jats:p>","DOI":"10.1038\/s41598-024-73200-6","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T02:02:04Z","timestamp":1728871324000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["24 Months clinical prospective of proximal restorations with repeated preheating bulk fill composite up to ten cycles: randomized controlled trial"],"prefix":"10.1038","volume":"14","author":[{"given":"Islam","family":"Ibrahim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba","family":"Helal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shereen Hafez","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Riad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,14]]},"reference":[{"key":"73200_CR1","doi-asserted-by":"crossref","unstructured":"Favoreto, M. 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The trial was registered in () database in May, 2022, with unique identification number NCT05383768. An informed consent with an easy Arabic language as mother language of participants was signed by the recruited participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors certify that they have obtained all appropriate informed consent forms from patients. An informed consent with an easy Arabic language as mother language of participants was signed by the adult participants and for minors the informed consent was signed by the parent and\/or legal guardian. An informed consent was obtained from all subjects and\/or their legal guardian(s) for publication of identifying information\/images in an online open-access publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"23966"}}