{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:22:11Z","timestamp":1791177731078,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T00:00:00Z","timestamp":1727481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T00:00:00Z","timestamp":1727481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-73395-8","type":"journal-article","created":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T12:01:50Z","timestamp":1727524910000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Incidence and risk factor analysis of neovascular glaucoma following vitrectomy in patients with proliferative diabetic retinopathy"],"prefix":"10.1038","volume":"14","author":[{"given":"Sunjin","family":"Hwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeon Hee","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng Xian","family":"Thng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Hee","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Ho","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Un","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,28]]},"reference":[{"key":"73395_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11892-016-0787-6","volume":"16","author":"MH Berrocal","year":"2016","unstructured":"Berrocal, M. H., Acaba, L. A. & Acaba, A. Surgery for diabetic eye complications. Curr. Diab Rep. 16, 1\u20137 (2016).","journal-title":"Curr. Diab Rep."},{"issue":"10","key":"73395_CR2","first-page":"736","volume":"24","author":"S Wahab","year":"2014","unstructured":"Wahab, S. & Hargun, L. D. Combined phacoemulsification, vitrectomy and endolaser photocoagulation in patients with diabetic retinopathy and cataract. J. Coll. Phys. Surg. Pak.. 24(10), 736\u2013739 (2014).","journal-title":"J. Coll. Phys. Surg. Pak."},{"key":"73395_CR3","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1007\/s10384-015-0396-y","volume":"59","author":"R Yokota","year":"2015","unstructured":"Yokota, R. et al. Comparison of microinsicion vitrectomy and conventional 20-gauge vitrectomy for severe proliferative diabetic retinopathy. Jpn. J. Ophthalmol. 59, 288\u2013294 (2015).","journal-title":"Jpn. J. Ophthalmol."},{"issue":"1","key":"73395_CR4","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.ajo.2013.02.008","volume":"156","author":"Z-H Zhang","year":"2013","unstructured":"Zhang, Z-H. et al. Vitrectomy with or without preoperative intravitreal bevacizumab for proliferative diabetic retinopathy: a meta-analysis of randomized controlled trials. Am. J. Ophthalmol. 156(1), 106\u2013115 (2013). e102.","journal-title":"Am. J. Ophthalmol."},{"issue":"6","key":"73395_CR5","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1097\/00006982-200312000-00003","volume":"23","author":"H Enaida","year":"2003","unstructured":"Enaida, H. et al. Possible benefits of triamcinolone-assisted pars plana vitrectomy for retinal diseases. Retina. 23(6), 764\u2013770 (2003).","journal-title":"Retina"},{"issue":"4","key":"73395_CR6","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.survophthal.2004.04.010","volume":"49","author":"KV Chalam","year":"2004","unstructured":"Chalam, K. V. & Shah, V. A. Optics of wide-angle panoramic viewing system\u2013assisted vitreous surgery. Surv. Ophthalmol. 49(4), 437\u2013445 (2004).","journal-title":"Surv. Ophthalmol."},{"key":"73395_CR7","doi-asserted-by":"crossref","unstructured":"Sakamoto, M., Hashimoto, R., Yoshida, I., Ubuka, M. & Maeno, T. Risk factors for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy. Clin. Ophthalmol. 2323\u20132329. (2018).","DOI":"10.2147\/OPTH.S184959"},{"key":"73395_CR8","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1007\/s13300-019-0644-0","volume":"10","author":"X Liang","year":"2019","unstructured":"Liang, X. et al. Frequency and risk factors for neovascular glaucoma after vitrectomy in eyes with diabetic retinopathy: an observational study. Diabetes Ther. 10, 1801\u20131809 (2019).","journal-title":"Diabetes Ther."},{"issue":"7","key":"73395_CR9","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1097\/IJG.0b013e31824d514a","volume":"22","author":"A Goto","year":"2013","unstructured":"Goto, A. et al. Frequency and risk factors for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy. J. Glaucoma. 22(7), 572\u2013576 (2013).","journal-title":"J. Glaucoma"},{"issue":"10","key":"73395_CR10","doi-asserted-by":"publisher","first-page":"e6263","DOI":"10.1097\/MD.0000000000006263","volume":"96","author":"J Kwon","year":"2017","unstructured":"Kwon, J., Jee, D. & La, T. Y. Neovascular glaucoma after vitrectomy in patients with proliferative diabetic retinopathy. Medicine. 96(10), e6263 (2017).","journal-title":"Medicine"},{"issue":"7","key":"73395_CR11","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/S1607-551X(09)70419-X","volume":"23","author":"H-Y Tseng","year":"2007","unstructured":"Tseng, H-Y., Wu, W-C. & Hsu, S-Y. Comparison of vitrectomy alone and combined vitrectomy, phacoemulsification and intraocular lens implantation for proliferative diabetic retinopathy. Kaohsiung J. Med. Sci. 23(7), 339\u2013343 (2007).","journal-title":"Kaohsiung J. Med. Sci."},{"issue":"10","key":"73395_CR12","doi-asserted-by":"publisher","first-page":"1960","DOI":"10.1097\/IAE.0000000000000171","volume":"34","author":"PS Silva","year":"2014","unstructured":"Silva, P. S. et al. Visual outcomes from pars plana vitrectomy versus combined pars plana vitrectomy, phacoemulsification, and intraocular lens implantation in patients with diabetes. Retina. 34(10), 1960\u20131968 (2014).","journal-title":"Retina"},{"issue":"1","key":"73395_CR13","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1186\/s12886-023-03071-4","volume":"23","author":"S Wang","year":"2023","unstructured":"Wang, S. et al. Influencing factors of low vision 2 years after vitrectomy for proliferative diabetic retinopathy: an observational study. BMC Ophthalmol. 23(1), 309 (2023).","journal-title":"BMC Ophthalmol."},{"issue":"6","key":"73395_CR14","doi-asserted-by":"publisher","first-page":"3057","DOI":"10.1177\/1120672120980686","volume":"31","author":"D Sun","year":"2021","unstructured":"Sun, D. et al. The incidence and risk factors of neovascular glaucoma secondary to proliferative diabetic retinopathy after vitrectomy. Eur. J. Ophthalmol. 31(6), 3057\u20133067 (2021).","journal-title":"Eur. J. Ophthalmol."},{"issue":"1","key":"73395_CR15","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1111\/j.1755-3768.1988.tb08544.x","volume":"66","author":"P Summanen","year":"1988","unstructured":"Summanen, P. Neovascular glaucoma following vitrectomy for diabetic eye disease. Acta Ophthalmol. 66(1), 110\u2013116 (1988).","journal-title":"Acta Ophthalmol."},{"key":"73395_CR16","doi-asserted-by":"crossref","unstructured":"SooHoo, J. R., Seibold, L. K. & Kahook, M. Y. Recent advances in the management of neovascular glaucoma. Paper presented at: Sem Ophthalmol. (2013).","DOI":"10.3109\/08820538.2012.730103"},{"key":"73395_CR17","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s00417-008-0980-7","volume":"247","author":"E Stef\u00e1nsson","year":"2009","unstructured":"Stef\u00e1nsson, E. Physiology of vitreous surgery. Graefes Arch. Clin. Exp. Ophthalmol. 247, 147\u2013163 (2009).","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"73395_CR18","doi-asserted-by":"publisher","first-page":"100845","DOI":"10.1016\/j.preteyeres.2020.100845","volume":"78","author":"DW Smith","year":"2020","unstructured":"Smith, D. W., Lee, C-J. & Gardiner, B. S. No flow through the vitreous humor: how strong is the evidence? Prog. Ret. Eye Res. 78, 100845 (2020).","journal-title":"Prog .Ret. Eye Res."},{"key":"73395_CR19","doi-asserted-by":"publisher","first-page":"S66","DOI":"10.1007\/BF02343050","volume":"234","author":"N Maeda","year":"1996","unstructured":"Maeda, N. & Tano, Y. Intraocular oxygen tension in eyes with proliferative diabetic retinopathy with and without vitreous. Graefes Arch. Clin. Exp. Ophthalmol. 234, S66\u2013S69 (1996).","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"73395_CR20","doi-asserted-by":"crossref","unstructured":"Chen, H-J., Ma, Z-Z., Li, Y. & Wang, C-G. Change of vascular endothelial growth factor levels following vitrectomy in eyes with proliferative Diabetic Retinopathy. J. Ophthalmol. 2019. (2019).","DOI":"10.1155\/2019\/6764932"},{"issue":"11","key":"73395_CR21","doi-asserted-by":"publisher","first-page":"6523","DOI":"10.1167\/iovs.15-16793","volume":"56","author":"K Kovacs","year":"2015","unstructured":"Kovacs, K. et al. Angiogenic and inflammatory vitreous biomarkers associated with increasing levels of retinal ischemia. Invest. Ophthalmol. Vis. Sci. 56(11), 6523\u20136530 (2015).","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"9","key":"73395_CR22","doi-asserted-by":"publisher","first-page":"107641","DOI":"10.1016\/j.jdiacomp.2020.107641","volume":"34","author":"S Song","year":"2020","unstructured":"Song, S., Yu, X., Zhang, P. & Dai, H. Increased levels of cytokines in the aqueous humor correlate with the severity of diabetic retinopathy. J. Diabetes Comp. 34(9), 107641 (2020).","journal-title":"J. Diabetes Comp."},{"key":"73395_CR23","doi-asserted-by":"crossref","unstructured":"Mohapatra, A., Sudharshan, S., Majumder, P. D., Sreenivasan, J. & Raman, R. Clinical profile and ocular morbidities in patients with both Diabetic Retinopathy and Uveitis. Ophthalmol. Sci. 100511. (2024).","DOI":"10.1016\/j.xops.2024.100511"},{"key":"73395_CR24","doi-asserted-by":"crossref","unstructured":"Kwon, J. & Sung, K. R. Effect of preoperative intravitreal bevacizumab on the surgical outcome of neovascular glaucoma at different stages. J Ophthalmol. 2017. (2017).","DOI":"10.1155\/2017\/7672485"},{"issue":"2","key":"73395_CR25","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1097\/ICU.0000000000000239","volume":"27","author":"AA Aref","year":"2016","unstructured":"Aref, A. A. Current management of glaucoma and vascular occlusive disease. Curr. Opi. Ophthalmol. 27(2), 140\u2013145 (2016).","journal-title":"Curr. Opi. Ophthalmol."},{"issue":"6","key":"73395_CR26","doi-asserted-by":"publisher","first-page":"855","DOI":"10.18240\/ijo.2021.06.10","volume":"14","author":"F Al Sarireh","year":"2021","unstructured":"Al Sarireh, F., Alrawashdeh, H. M., Al Zubi, K. & Al Salem, K. Role of bevacizumab intraocular injection in the management of neovascular glaucoma. Int. J. Ophthalmol. 14(6), 855 (2021).","journal-title":"Int. J. Ophthalmol."},{"issue":"6","key":"73395_CR27","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1016\/j.ajo.2010.01.008","volume":"149","author":"Y Saito","year":"2010","unstructured":"Saito, Y. et al. Clinical factors related to recurrence of anterior segment neovascularization after treatment including intravitreal bevacizumab. Am. J. Ophthalmol. 149(6), 964\u2013972 (2010). e961.","journal-title":"Am. J. Ophthalmol."},{"issue":"4","key":"73395_CR28","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1161\/STROKEAHA.108.540781","volume":"40","author":"P Appelros","year":"2009","unstructured":"Appelros, P., Stegmayr, B. & Ter\u00e9nt, A. Sex differences in stroke epidemiology: a systematic review. Stroke. 40(4), 1082\u20131090 (2009).","journal-title":"Stroke"},{"issue":"2","key":"73395_CR29","first-page":"52","volume":"18","author":"G Sanborn","year":"1986","unstructured":"Sanborn, G., Symes, D. & Magargal, L. Fundus-iris fluorescein angiography: evaluation of its use in the diagnosis of rubeosis iridis. Ann. Ophthalmol. 18(2), 52\u201358 (1986).","journal-title":"Ann. Ophthalmol."},{"issue":"13","key":"73395_CR30","doi-asserted-by":"publisher","first-page":"4360","DOI":"10.1167\/iovs.18-25858","volume":"60","author":"PI Sia","year":"2019","unstructured":"Sia, P. I., Wood, J. P., Chidlow, G. & Casson, R. Creatine is neuroprotective to retinal neurons in vitro but not in vivo. Invest. Ophthalmol. Vis. Sci. 60(13), 4360\u20134377 (2019).","journal-title":"Invest. Ophthalmol. Vis. Sci."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73395-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73395-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73395-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T12:04:44Z","timestamp":1727525084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73395-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,28]]},"references-count":30,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["73395"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-73395-8","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,28]]},"assertion":[{"value":"19 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"22490"}}