{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T04:32:08Z","timestamp":1793939528686,"version":"4.8.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-73756-3","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T04:02:04Z","timestamp":1731384124000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Air pollution exposure and head and neck cancer incidence"],"prefix":"10.1038","volume":"14","author":[{"given":"John","family":"Peleman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyuan","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanujit","family":"Dey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Dilger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret B.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youn Soo","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murrugapan","family":"Ramanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Mady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Cramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stella E.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"73756_CR1","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1016\/s1470-2045(13)70487-x","volume":"14","author":"D Loomis","year":"2013","unstructured":"Loomis, D. et al. The carcinogenicity of outdoor air pollution. Lancet Oncol 14, 1262\u20131263. https:\/\/doi.org\/10.1016\/s1470-2045(13)70487-x (2013).","journal-title":"Lancet Oncol"},{"key":"73756_CR2","doi-asserted-by":"publisher","first-page":"6038","DOI":"10.7150\/jca.48296","volume":"11","author":"TTT Vo","year":"2020","unstructured":"Vo, T. T. T. et al. Surfactin from Bacillus subtilis attenuates ambient air particulate matter-promoted human oral cancer cells metastatic potential. J. Cancer 11, 6038\u20136049. https:\/\/doi.org\/10.7150\/jca.48296 (2020).","journal-title":"J. Cancer"},{"key":"73756_CR3","doi-asserted-by":"publisher","first-page":"243","DOI":"10.3390\/ijms18020243","volume":"18","author":"H Traboulsi","year":"2017","unstructured":"Traboulsi, H. et al. Inhaled pollutants: the molecular scene behind respiratory and systemic diseases associated with ultrafine particulate matter. Int. J. Mol. Sci. 18, 243. https:\/\/doi.org\/10.3390\/ijms18020243 (2017).","journal-title":"Int. J. Mol. Sci."},{"key":"73756_CR4","doi-asserted-by":"publisher","first-page":"4764720","DOI":"10.1155\/2022\/4764720","volume":"2022","author":"Y Jiao","year":"2022","unstructured":"Jiao, Y., Gong, C., Wang, S., Duan, Y. & Zhang, Y. The influence of air pollution on pulmonary disease incidence analyzed based on grey correlation analysis. Contrast Media Mol. Imaging 2022, 4764720. https:\/\/doi.org\/10.1155\/2022\/4764720 (2022).","journal-title":"Contrast Media Mol. Imaging"},{"key":"73756_CR5","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1038\/s41569-020-0371-2","volume":"17","author":"SG Al-Kindi","year":"2020","unstructured":"Al-Kindi, S. G., Brook, R. D., Biswal, S. & Rajagopalan, S. Environmental determinants of cardiovascular disease: lessons learned from air pollution. Nat. Rev. Cardiol. 17, 656\u2013672. https:\/\/doi.org\/10.1038\/s41569-020-0371-2 (2020).","journal-title":"Nat. Rev. Cardiol."},{"key":"73756_CR6","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/j.jhep.2021.10.016","volume":"76","author":"B Guo","year":"2022","unstructured":"Guo, B. et al. Exposure to air pollution is associated with an increased risk of metabolic dysfunction-associated fatty liver disease. J. Hepatol. 76, 518\u2013525. https:\/\/doi.org\/10.1016\/j.jhep.2021.10.016 (2022).","journal-title":"J. Hepatol."},{"key":"73756_CR7","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1289\/ehp\/1408092","volume":"122","author":"GB Hamra","year":"2014","unstructured":"Hamra, G. B. et al. Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis. Environ. Health Perspect. 122, 906\u2013911. https:\/\/doi.org\/10.1289\/ehp\/1408092 (2014).","journal-title":"Environ. Health Perspect."},{"key":"73756_CR8","doi-asserted-by":"publisher","first-page":"2450","DOI":"10.1002\/ijc.32575","volume":"146","author":"L Bai","year":"2020","unstructured":"Bai, L. et al. Exposure to ambient air pollution and the incidence of lung cancer and breast cancer in the Ontario population health and environment cohort. Int. J. Cancer 146, 2450\u20132459. https:\/\/doi.org\/10.1002\/ijc.32575 (2020).","journal-title":"Int. J. Cancer"},{"key":"73756_CR9","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1016\/s1470-2045(13)70279-1","volume":"14","author":"O Raaschou-Nielsen","year":"2013","unstructured":"Raaschou-Nielsen, O. et al. Air pollution and lung cancer incidence in 17 European cohorts: Prospective analyses from the European study of cohorts for air pollution effects (ESCAPE). Lancet Oncol. 14, 813\u2013822. https:\/\/doi.org\/10.1016\/s1470-2045(13)70279-1 (2013).","journal-title":"Lancet Oncol."},{"key":"73756_CR10","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1136\/thoraxjnl-2019-213722","volume":"75","author":"ZY Zhang","year":"2020","unstructured":"Zhang, Z. Y. et al. Association between particulate matter air pollution and lung cancer. Thorax 75, 85\u201387. https:\/\/doi.org\/10.1136\/thoraxjnl-2019-213722 (2020).","journal-title":"Thorax"},{"key":"73756_CR11","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1093\/jnci\/djad170","volume":"116","author":"AJ White","year":"2023","unstructured":"White, A. J. et al. Ambient fine particulate matter and breast cancer incidence in a large prospective US cohort. JNCI J. Natl. Cancer Instit. 116, 53\u201360. https:\/\/doi.org\/10.1093\/jnci\/djad170 (2023).","journal-title":"JNCI J. Natl. Cancer Instit."},{"key":"73756_CR12","doi-asserted-by":"publisher","DOI":"10.1289\/ehp7246","volume":"128","author":"NC Coleman","year":"2020","unstructured":"Coleman, N. C. et al. Fine particulate matter exposure and cancer incidence: Analysis of SEER cancer registry data from 1992\u20132016. Environ. Health Perspect. 128, 107004. https:\/\/doi.org\/10.1289\/ehp7246 (2020).","journal-title":"Environ. Health Perspect."},{"key":"73756_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2024.106691","volume":"150","author":"H Ochoa Scussiatto","year":"2024","unstructured":"Ochoa Scussiatto, H. et al. Air pollution is associated with increased incidence-rate of head and neck cancers: A nationally representative ecological study. Oral Oncol. 150, 106691. https:\/\/doi.org\/10.1016\/j.oraloncology.2024.106691 (2024).","journal-title":"Oral Oncol."},{"key":"73756_CR14","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1016\/s0140-6736(08)60728-x","volume":"371","author":"A Argiris","year":"2008","unstructured":"Argiris, A., Karamouzis, M. V., Raben, D. & Ferris, R. L. Head and neck cancer. Lancet 371, 1695\u20131709. https:\/\/doi.org\/10.1016\/s0140-6736(08)60728-x (2008).","journal-title":"Lancet"},{"key":"73756_CR15","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1038\/s41571-022-00603-7","volume":"19","author":"M Lechner","year":"2022","unstructured":"Lechner, M., Liu, J., Masterson, L. & Fenton, T. R. HPV-associated oropharyngeal cancer: Epidemiology, molecular biology and clinical management. Nat. Rev. Clin. Oncol. 19, 306\u2013327. https:\/\/doi.org\/10.1038\/s41571-022-00603-7 (2022).","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"73756_CR16","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1038\/2281056a0","volume":"228","author":"H Zur Hausen","year":"1970","unstructured":"Zur Hausen, H. et al. EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx. Nature 228, 1056\u20131058. https:\/\/doi.org\/10.1038\/2281056a0 (1970).","journal-title":"Nature"},{"key":"73756_CR17","doi-asserted-by":"publisher","first-page":"5071","DOI":"10.1021\/acs.est.8b06875","volume":"53","author":"J Meng","year":"2019","unstructured":"Meng, J. et al. Estimated long-term (1981\u20132016) concentrations of ambient fine particulate matter across North America from chemical transport modeling, satellite remote sensing, and ground-based measurements. Environ. Sci. Technol. 53, 5071\u20135079. https:\/\/doi.org\/10.1021\/acs.est.8b06875 (2019).","journal-title":"Environ. Sci. Technol."},{"key":"73756_CR18","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.2105\/ajph.2014.302313","volume":"105","author":"L Dwyer-Lindgren","year":"2015","unstructured":"Dwyer-Lindgren, L. et al. Drinking patterns in US counties from 2002 to 2012. Am. J. Public Health 105, 1120\u20131127. https:\/\/doi.org\/10.2105\/ajph.2014.302313 (2015).","journal-title":"Am. J. Public Health"},{"key":"73756_CR19","unstructured":"Institute, U. O. W. P. H. (County Health Rankings & Roadmaps, Online, 2022)."},{"key":"73756_CR20","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1478-7954-12-5","volume":"12","author":"L Dwyer-Lindgren","year":"2014","unstructured":"Dwyer-Lindgren, L. et al. Cigarette smoking prevalence in US counties: 1996\u20132012. Popul. Health Metr. 12, 5. https:\/\/doi.org\/10.1186\/1478-7954-12-5 (2014).","journal-title":"Popul. Health Metr."},{"key":"73756_CR21","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.envres.2018.12.032","volume":"171","author":"H Kim","year":"2019","unstructured":"Kim, H. & Lee, J. T. On inferences about lag effects using lag models in air pollution time-series studies. Environ. Res. 171, 134\u2013144. https:\/\/doi.org\/10.1016\/j.envres.2018.12.032 (2019).","journal-title":"Environ. Res."},{"key":"73756_CR22","doi-asserted-by":"publisher","first-page":"2513","DOI":"10.1056\/nejmoa1702747","volume":"376","author":"Q Di","year":"2017","unstructured":"Di, Q. et al. Air pollution and mortality in the medicare population. New England J. Med. 376, 2513\u20132522. https:\/\/doi.org\/10.1056\/nejmoa1702747 (2017).","journal-title":"New England J. Med."},{"key":"73756_CR23","unstructured":"Bert, B. et al. Mortality and morbidity effects of long-term exposure to low-level PM(2.5), BC, NO(2), and O(3): An analysis of European cohorts in the ELAPSE project. Res. Rep. Health Eff. Inst. 1\u2013127 (2021)."},{"key":"73756_CR24","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3390\/cli8010012","volume":"8","author":"JS Hoffman","year":"2020","unstructured":"Hoffman, J. S., Shandas, V. & Pendleton, N. The effects of historical housing policies on resident exposure to intra-urban heat: A study of 108 US urban areas. Climate 8, 12 (2020).","journal-title":"Climate"},{"key":"73756_CR25","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.jaci.2020.04.035","volume":"146","author":"EB Brandt","year":"2020","unstructured":"Brandt, E. B., Beck, A. F. & Mersha, T. B. Air pollution, racial disparities, and COVID-19 mortality. J. Allergy Clin. Immunol. 146, 61\u201363. https:\/\/doi.org\/10.1016\/j.jaci.2020.04.035 (2020).","journal-title":"J. Allergy Clin. Immunol."},{"key":"73756_CR26","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21632","author":"MC Turner","year":"2020","unstructured":"Turner, M. C. et al. Outdoor air pollution and cancer: An overview of the current evidence and public health recommendations. CA Cancer J. Clin. https:\/\/doi.org\/10.3322\/caac.21632 (2020).","journal-title":"CA Cancer J. Clin."},{"key":"73756_CR27","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.envres.2012.09.008","volume":"120","author":"A Sapkota","year":"2013","unstructured":"Sapkota, A. et al. Indoor air pollution from solid fuels and risk of upper aerodigestive tract cancers in Central and Eastern Europe. Environ. Res. 120, 90\u201395. https:\/\/doi.org\/10.1016\/j.envres.2012.09.008 (2013).","journal-title":"Environ. Res."},{"key":"73756_CR28","doi-asserted-by":"publisher","DOI":"10.4209\/aaqr.210060","volume":"21","author":"MS Ku","year":"2021","unstructured":"Ku, M. S., Siewchaisakul, P., Yen, A. M. F. & Liu, C. Y. The association between ambient fine particulate matter and oral neoplasm among smokers and betel quids chewers. Aerosol Air. Quality Res. 21, 210060. https:\/\/doi.org\/10.4209\/aaqr.210060 (2021).","journal-title":"Aerosol Air. Quality Res."},{"key":"73756_CR29","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1136\/jim-2016-000263","volume":"67","author":"YH Chu","year":"2019","unstructured":"Chu, Y. H. et al. Association between fine particulate matter and oral cancer among Taiwanese men. J. Investig. Med. 67, 34\u201338. https:\/\/doi.org\/10.1136\/jim-2016-000263 (2019).","journal-title":"J. Investig. Med."},{"key":"73756_CR30","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1136\/jim-2019-001119","volume":"68","author":"H-C Huang","year":"2020","unstructured":"Huang, H.-C. et al. Association between coarse particulate matter (PM10\u20132.5) and nasopharyngeal carcinoma among Taiwanese men. J. Investig. Med. 68, 419\u2013424. https:\/\/doi.org\/10.1136\/jim-2019-001119 (2020).","journal-title":"J. Investig. Med."},{"key":"73756_CR31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204568","volume":"13","author":"H-C Fan","year":"2018","unstructured":"Fan, H.-C. et al. Increased risk of incident nasopharyngeal carcinoma with exposure to air pollution. PLOS ONE 13, e0204568. https:\/\/doi.org\/10.1371\/journal.pone.0204568 (2018).","journal-title":"PLOS ONE"},{"key":"73756_CR32","doi-asserted-by":"publisher","first-page":"1824","DOI":"10.3390\/ijerph17061824","volume":"17","author":"T Yang","year":"2020","unstructured":"Yang, T., Liu, Y., Zhao, W., Chen, Z. & Deng, J. Association of ambient air pollution with nasopharyngeal carcinoma incidence in ten large Chinese Cities, 2006\u20132013. Int. J. Environ. Res. Public Health 17, 1824. https:\/\/doi.org\/10.3390\/ijerph17061824 (2020).","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"73756_CR33","doi-asserted-by":"publisher","first-page":"S6","DOI":"10.1016\/s1470-2045(22)00405-3","volume":"23","author":"P Yu","year":"2022","unstructured":"Yu, P. et al. Associations between long-term exposure to wildfire-related particulate matter and site-specific cancer mortality: A national study in Brazil, 2010\u201316. Lancet Oncol. 23, S6. https:\/\/doi.org\/10.1016\/s1470-2045(22)00405-3 (2022).","journal-title":"Lancet Oncol."},{"key":"73756_CR34","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1590\/s0102-311x2012000900012","volume":"28","author":"Y Yanagi","year":"2012","unstructured":"Yanagi, Y., Assun\u00e7\u00e3o, J. V. D. & Barrozo, L. V. The impact of atmospheric particulate matter on cancer incidence and mortality in the city of S\u00e3o Paulo. Brazil. Cadernos de Sa\u00fade P\u00fablica 28, 1737\u20131748. https:\/\/doi.org\/10.1590\/s0102-311x2012000900012 (2012).","journal-title":"Brazil. Cadernos de Sa\u00fade P\u00fablica"},{"key":"73756_CR35","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1136\/thoraxjnl-2015-207927","volume":"71","author":"SP Eckel","year":"2016","unstructured":"Eckel, S. P. et al. Air pollution affects lung cancer survival. Thorax 71, 891\u2013898. https:\/\/doi.org\/10.1136\/thoraxjnl-2015-207927 (2016).","journal-title":"Thorax"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73756-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73756-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73756-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T05:05:22Z","timestamp":1731387922000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73756-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,12]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["73756"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-73756-3","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,12]]},"assertion":[{"value":"26 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"26998"}}