{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T14:18:00Z","timestamp":1784816280421,"version":"3.55.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-73880-0","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T11:02:09Z","timestamp":1728385329000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Enhancing pectus excavatum diagnosis with an automated batch evaluation tool for chest computed tomography images"],"prefix":"10.1038","volume":"14","author":[{"given":"Yu-Jiun","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Shiang","family":"Tzeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Yu","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeung-Leung","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Hao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"key":"73880_CR1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/978-3-319-23968-2_7","volume-title":"Chest Wall Deformities and Corrective Procedures","author":"M Martinez-Ferro","year":"2016","unstructured":"Martinez-Ferro, M. Indexes for pectus deformities. In Chest Wall Deformities and Corrective Procedures (eds Kolvekar, S. & Pilegaard, H.) 35\u201360 (Springer, 2016)."},{"key":"73880_CR2","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/S0022-3468(87)80585-7","volume":"22","author":"JA Haller Jr","year":"1987","unstructured":"Haller, J. A. Jr., Kramer, S. S. & Lietman, S. A. Use of CT scans in selection of patients for pectus excavatum surgery: A preliminary report. J. Pediatr. Surg. 22, 904\u2013906 (1987).","journal-title":"J. Pediatr. Surg."},{"key":"73880_CR3","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1007\/s00247-003-1116-1","volume":"34","author":"SW Daunt","year":"2004","unstructured":"Daunt, S. W., Cohen, J. H. & Miller, S. F. Age-related normal ranges for the Haller index in children. Pediatr. Radiol. 34, 326\u2013330 (2004).","journal-title":"Pediatr. Radiol."},{"key":"73880_CR4","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.1007\/s00247-010-1681-z","volume":"40","author":"G Khanna","year":"2010","unstructured":"Khanna, G., Jaju, A., Don, S., Keys, T. & Hildebolt, C. F. Comparison of Haller index values calculated with chest radiographs versus CT for pectus excavatum evaluation. Pediatr. Radiol. 40, 1763\u20131767 (2010).","journal-title":"Pediatr. Radiol."},{"key":"73880_CR5","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/s12098-007-0007-0","volume":"74","author":"A Kilda","year":"2007","unstructured":"Kilda, A., Basevicius, A., Barauskas, V., Lukosevicius, S. & Ragaisis, D. Radiological assessment of children with pectus excavatum. Indian J. Pediatr. 74, 143\u2013147 (2007).","journal-title":"Indian J. Pediatr."},{"key":"73880_CR6","doi-asserted-by":"publisher","first-page":"2270","DOI":"10.1016\/j.jpedsurg.2011.09.009","volume":"46","author":"S Peter","year":"2011","unstructured":"Peter, S. A novel measure for pectus excavatum: The correction index. J. Pediatr. Surg. 46, 2270\u20132273 (2011).","journal-title":"J. Pediatr. Surg."},{"key":"73880_CR7","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1016\/j.athoracsur.2013.12.050","volume":"97","author":"PM Poston","year":"2014","unstructured":"Poston, P. M. et al. The correction index: Setting the standard for recommending operative repair of pectus excavatum. Ann. Thorac. Surg. 97, 1176\u20131180 (2014).","journal-title":"Ann. Thorac. Surg."},{"key":"73880_CR8","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1016\/j.jpedsurg.2006.03.003","volume":"41","author":"ML Lawson","year":"2006","unstructured":"Lawson, M. L. et al. Reliability of a standardized protocol to calculate cross-sectional chest area and severity indices to evaluate pectus excavatum. J. Pediatr. Surg. 41, 1219\u20131225 (2006).","journal-title":"J. Pediatr. Surg."},{"key":"73880_CR9","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s11517-008-0367-2","volume":"46","author":"HC Kim","year":"2008","unstructured":"Kim, H. C. et al. Development of automatized new indices for radiological assessment of chest-wall deformity and its quantitative evaluation. Med. Biol. Eng. Comput. 46, 815\u2013823 (2008).","journal-title":"Med. Biol. Eng. Comput."},{"key":"73880_CR10","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1016\/j.athoracsur.2016.05.079","volume":"102","author":"JH Choi","year":"2016","unstructured":"Choi, J. H., Park, I. K., Kim, Y. T., Kim, W. S. & Kang, C. H. Classification of pectus excavatum according to objective parameters from chest computed tomography. Ann. Thorac. Surg. 102, 1886\u20131891 (2016).","journal-title":"Ann. Thorac. Surg."},{"key":"73880_CR11","first-page":"137","volume":"18","author":"L Papp","year":"2010","unstructured":"Papp, L., Juhasz, R., Travar, S., Kolli, A. & Sorantin, E. Automatic detection and characterization of funnel chest based on spiral CT. J. Xray Sci. Technol. 18, 137\u2013144 (2010).","journal-title":"J. Xray Sci. Technol."},{"key":"73880_CR12","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1007\/s11517-010-0612-3","volume":"48","author":"HC Kim","year":"2010","unstructured":"Kim, H. C. et al. Fully automatic initialization method for quantitative assessment of chest-wall deformity in funnel chest patients. Med. Biol. Eng. Comput. 48, 589\u2013595 (2010).","journal-title":"Med. Biol. Eng. Comput."},{"key":"73880_CR13","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s12880-022-00754-0","volume":"22","author":"R Tro","year":"2022","unstructured":"Tro, R. et al. A new tool for assessing pectus excavatum by a semi-automatic image processing pipeline calculating the classical severity indexes and a new marker: The volumetric correction index. BMC Med. Imaging 22, 30 (2022).","journal-title":"BMC Med. Imaging"},{"key":"73880_CR14","doi-asserted-by":"crossref","unstructured":"Shoemake, K. In Graphics Gems IV (ed. Heckbert) 222\u2013229 (Morgan Kaufmann, 1994).","DOI":"10.1016\/B978-0-12-336156-1.50030-6"},{"key":"73880_CR15","first-page":"63","volume":"68","author":"A Prabin","year":"2014","unstructured":"Prabin, A. & Veerappan, J. Automatic segmentation of lung CT images by CC based region growing. J. Theor. Appl. Inf. Technol. 68, 63\u201369 (2014).","journal-title":"J. Theor. Appl. Inf. Technol."},{"key":"73880_CR16","unstructured":"Fujita, T. The Human Anatomy (Nankodo, 1968)."},{"key":"73880_CR17","first-page":"111","volume":"56","author":"VY Golikov","year":"1989","unstructured":"Golikov, V. Y. & Nikitin, V. V. Estimation of the mean organ doses and the effective dose equivalent from RANDO phantom measurements. Health Phys. 56, 111\u2013115 (1989).","journal-title":"Health Phys."},{"key":"73880_CR18","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1109\/72.80210","volume":"1","author":"DF Specht","year":"1990","unstructured":"Specht, D. F. Probabilistic neural networks and the polynomial Adaline as complementary techniques for classification. IEEE Trans. Neural Netw. 1, 111\u2013121 (1990).","journal-title":"IEEE Trans. Neural Netw."},{"key":"73880_CR19","first-page":"5388","volume":"2020","author":"M Servi","year":"2020","unstructured":"Servi, M. et al. Outpatient monitoring of pectus excavatum: A neural network-based approach. Annu. Int. Conf. IEEE Eng. Med. Biol. Soc. 2020, 5388\u20135393 (2020).","journal-title":"Annu. Int. Conf. IEEE Eng. Med. Biol. Soc."},{"key":"73880_CR20","doi-asserted-by":"publisher","first-page":"20294","DOI":"10.1038\/s41598-020-77361-y","volume":"10","author":"L Lai","year":"2020","unstructured":"Lai, L., Cai, S., Huang, L., Zhou, H. & Xie, L. Computer-aided diagnosis of pectus excavatum using CT images and deep learning methods. Sci. Rep. 10, 20294 (2020).","journal-title":"Sci. Rep."},{"key":"73880_CR21","doi-asserted-by":"publisher","first-page":"760","DOI":"10.3390\/biomedicines11030760","volume":"11","author":"YJ Fan","year":"2023","unstructured":"Fan, Y. J. et al. Machine learning: Using Xception, deep convolutional neural network architecture, to implement pectus excavatum diagnostic tool from frontal-view chest X-rays. Biomedicines 11, 760 (2023).","journal-title":"Biomedicines"},{"key":"73880_CR22","doi-asserted-by":"publisher","first-page":"111276","DOI":"10.1016\/j.ejrad.2023.111276","volume":"170","author":"M Selles","year":"2024","unstructured":"Selles, M., van Osch, J. A. C., Maas, M., Boomsma, M. F. & Wellenberg, R. H. H. Advances in metal artifact reduction in CT images: A review of traditional and novel metal artifact reduction techniques. Eur. J. Radiol. 170, 111276 (2024).","journal-title":"Eur. J. Radiol."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73880-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73880-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73880-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T15:03:12Z","timestamp":1728658992000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-73880-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,8]]},"references-count":22,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["73880"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-73880-0","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4465212\/v1","asserted-by":"object"}]},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,8]]},"assertion":[{"value":"23 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"23468"}}