{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T23:25:02Z","timestamp":1794007502217,"version":"4.8.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Acre"},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["2014\/19286-4"],"award-info":[{"award-number":["2014\/19286-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["304743\/2017-8"],"award-info":[{"award-number":["304743\/2017-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-74177-y","type":"journal-article","created":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T02:03:02Z","timestamp":1727920982000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Acute kidney injury developed in the intensive care unit: a population-based prospective cohort study in the Brazilian Amazon"],"prefix":"10.1038","volume":"14","author":[{"given":"Fernando A. F.","family":"Melo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel A.","family":"Burdmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Macedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravindra","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirce M. T.","family":"Zanetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,3]]},"reference":[{"issue":"3","key":"74177_CR1","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1097\/SHK.0000000000001511","volume":"54","author":"Y Komaru","year":"2020","unstructured":"Komaru, Y. et al. Inverse correlation between incidence and mortality of acute kidney injury in critically ill patients: a systematic review. Shock54 (3), 280\u2013284 (2020).","journal-title":"Shock"},{"issue":"8","key":"74177_CR2","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1007\/s00134-015-3934-7","volume":"41","author":"EA Hoste","year":"2015","unstructured":"Hoste, E. A. et al. Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med.41 (8), 1411\u20131423 (2015).","journal-title":"Intensive Care Med."},{"issue":"10","key":"74177_CR3","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/s41581-018-0052-0","volume":"14","author":"EAJ Hoste","year":"2018","unstructured":"Hoste, E. A. J. et al. Global epidemiology and outcomes of acute kidney injury. Nat. Rev. Nephrol.14 (10), 607\u2013625 (2018).","journal-title":"Nat. Rev. Nephrol."},{"key":"74177_CR4","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1186\/s13054-015-1149-5","volume":"19","author":"CC Shiao","year":"2015","unstructured":"Shiao, C. C. et al. Long-term remote organ consequences following acute kidney injury. Crit. Care19, 438 (2015).","journal-title":"Crit. Care"},{"issue":"1","key":"74177_CR5","doi-asserted-by":"publisher","first-page":"e0226325","DOI":"10.1371\/journal.pone.0226325","volume":"15","author":"FAF Melo","year":"2020","unstructured":"Melo, F. A. F. et al. A systematic review and meta-analysis of acute kidney injury in the intensive care units of developed and developing countries. PLoS One15 (1), e0226325 (2020).","journal-title":"PLoS One"},{"issue":"8","key":"74177_CR6","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.2215\/CJN.04360514","volume":"10","author":"J Bouchard","year":"2015","unstructured":"Bouchard, J. et al. A prospective international multicenter study of AKI in the intensive care unit. Clin. J. Am. Soc. Nephrol.10 (8), 1324\u20131331 (2015).","journal-title":"Clin. J. Am. Soc. Nephrol."},{"issue":"9987","key":"74177_CR7","doi-asserted-by":"publisher","first-page":"2616","DOI":"10.1016\/S0140-6736(15)60126-X","volume":"385","author":"RL Mehta","year":"2015","unstructured":"Mehta, R. L. et al. International Society of Nephrology\u2019s 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology. Lancet385 (9987), 2616\u20132643 (2015).","journal-title":"Lancet"},{"key":"74177_CR8","unstructured":"IBGE Estados@. https:\/\/cidades.ibge.gov.br\/brasil\/ac\/pesquisa\/23\/25124?detalhes=true (Assessed 22 December 2022) (2015)."},{"key":"74177_CR9","unstructured":"Ministry of Cities- Brazilian Government. Sistema Nacional de Informa\u00e7\u00f5es sobre Saneamento Brazil: Ministry of Cities \u2013 Brazilian Government; 2014. https:\/\/www.gov.br\/mdr\/pt-br\/assuntos\/saneamento\/snis\/painel (Assessed 22 December 2022) (2016)."},{"key":"74177_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/kisup.2012.1","volume":"2","author":"Kidney Disease","year":"2012","unstructured":"Kidney Disease. Improving global outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int. Suppl.2, 1\u2013138 (2012).","journal-title":"Kidney Int. Suppl."},{"issue":"10032","key":"74177_CR11","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1016\/S0140-6736(16)30240-9","volume":"387","author":"RL Mehta","year":"2016","unstructured":"Mehta, R. L. et al. Recognition and management of acute kidney injury in the International Society of Nephrology 0by25 Global Snapshot: a multinational cross-sectional study. Lancet387 (10032), 2017\u20132025 (2016).","journal-title":"Lancet"},{"issue":"1","key":"74177_CR12","doi-asserted-by":"publisher","first-page":"e1003408","DOI":"10.1371\/journal.pmed.1003408","volume":"18","author":"E Macedo","year":"2021","unstructured":"Macedo, E. et al. Recognition and management of community-acquired acute kidney injury in low-resource settings in the ISN 0by25 trial: a multi-country feasibility study. PLoS Med.18 (1), e1003408 (2021).","journal-title":"PLoS Med."},{"issue":"4","key":"74177_CR13","doi-asserted-by":"publisher","first-page":"e1003969","DOI":"10.1371\/journal.pmed.1003969","volume":"19","author":"M Wainstein","year":"2022","unstructured":"Wainstein, M. et al. Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: a multinational study using the ISARIC-WHO clinical characterisation protocol. PLoS Med.19 (4), e1003969 (2022).","journal-title":"PLoS Med."},{"issue":"2","key":"74177_CR14","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/0009-8981(87)90293-2","volume":"168","author":"ML Knapp","year":"1987","unstructured":"Knapp, M. L. & Mayne, P. D. Development of an automated kinetic Jaff\u00e9 method designed to minimise bilirubin interference in plasma creatinine assays. Clin. Chim. Acta168 (2), 239\u2013246 (1987).","journal-title":"Clin. Chim. Acta"},{"issue":"4","key":"74177_CR15","doi-asserted-by":"publisher","first-page":"R144","DOI":"10.1186\/cc13977","volume":"18","author":"X Luo","year":"2014","unstructured":"Luo, X. et al. A comparison of different diagnostic criteria of acute kidney injury in critically ill patients. Crit. Care18 (4), R144 (2014).","journal-title":"Crit. Care"},{"issue":"1","key":"74177_CR16","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s12882-017-0487-8","volume":"18","author":"J Koeze","year":"2017","unstructured":"Koeze, J. et al. Incidence, timing and outcome of AKI in critically ill patients varies with the definition used and the addition of urine output criteria. BMC Nephrol.18 (1), 70 (2017).","journal-title":"BMC Nephrol."},{"issue":"7","key":"74177_CR17","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1093\/ndt\/gfu078","volume":"29","author":"R Lombardi","year":"2014","unstructured":"Lombardi, R. et al. Acute kidney injury in Latin America: a view on renal replacement therapy resources. Nephrol. Dial. Transpl.29 (7), 1369\u20131376 (2014).","journal-title":"Nephrol. Dial. Transpl."},{"issue":"5","key":"74177_CR18","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/j.kint.2016.09.051","volume":"91","author":"EA Burdmann","year":"2017","unstructured":"Burdmann, E. A. & Jha, V. Acute kidney injury due to tropical infectious diseases and animal venoms: a tale of 2 continents. Kidney Int.91 (5), 1033\u20131046 (2017).","journal-title":"Kidney Int."},{"issue":"10","key":"74177_CR19","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1093\/ndt\/gfz087","volume":"35","author":"N Srisawat","year":"2020","unstructured":"Srisawat, N. et al. The epidemiology and characteristics of acute kidney injury in the Southeast Asia intensive care unit: a prospective multicentre study. Nephrol. Dial. Transpl.35 (10), 1729\u20131738 (2020).","journal-title":"Nephrol. Dial. Transpl."},{"issue":"1","key":"74177_CR20","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1186\/s12916-020-01645-3","volume":"18","author":"N Sengthavisouk","year":"2020","unstructured":"Sengthavisouk, N. et al. Epidemiology and short-term outcomes of acute kidney injury among patients in the intensive care unit in Laos: a nationwide multicenter, prospective, and observational study. BMC Med.18 (1), 180 (2020).","journal-title":"BMC Med."},{"key":"74177_CR21","unstructured":"Health Agency of the State of Acre. Epidemiological bulletin. SUS [Internet]. https:\/\/agencia.ac.gov.br\/ (Assessed 22 December 2022)."},{"issue":"11","key":"74177_CR22","doi-asserted-by":"publisher","first-page":"2865","DOI":"10.1590\/S1413-81232012001100002","volume":"17","author":"MMA Assis","year":"2012","unstructured":"Assis, M. M. A. & Jesus, W. L. A. Access to health services: approaches, concepts, policies and analysis model. Ci\u00eanc Sa\u00fade Coletiva17 (11), 2865\u20132875 (2012).","journal-title":"Ci\u00eanc Sa\u00fade Coletiva"},{"issue":"12","key":"74177_CR23","doi-asserted-by":"publisher","first-page":"2820","DOI":"10.1590\/S0102-311X2007001200003","volume":"23","author":"O O\u2019Donnell","year":"2007","unstructured":"O\u2019Donnell, O. & Greece, T. Access to health care in developing countries: breaking down demand side barriers. Cad. Sa\u00fade P\u00fabl.23 (12), 2820\u20132834 (2007).","journal-title":"Cad. Sa\u00fade P\u00fabl."},{"issue":"11","key":"74177_CR24","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/0277-9536(87)90286-3","volume":"24","author":"EL Wong","year":"1987","unstructured":"Wong, E. L., Popkin, B. M., Guilkey, D. K. & Akin, J. S. Accessibility, quality of care and prenatal care use in the Philippines. Soc. Sci. Med.24 (11), 927\u2013944 (1987).","journal-title":"Soc. Sci. Med."},{"issue":"2","key":"74177_CR25","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/0047-2727(95)01530-2","volume":"61","author":"T Ducan","year":"1996","unstructured":"Ducan, T., Lavy, V. & Strauss, J. Public policy and anthropometric outcomes in the C\u00f4te d\u2019Ivoire. J. Public Econ.61 (2), 155\u2013192 (1996).","journal-title":"J. Public Econ."},{"issue":"4","key":"74177_CR26","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.ekir.2017.04.009","volume":"2","author":"J Cerd\u00e1","year":"2017","unstructured":"Cerd\u00e1, J. et al. Acute kidney injury recognition in low- and middle-income countries. Kidney Int. Rep.2 (4), 530\u2013543 (2017).","journal-title":"Kidney Int. Rep."},{"issue":"4","key":"74177_CR27","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/j.ekir.2017.03.014","volume":"2","author":"K Kashani","year":"2017","unstructured":"Kashani, K. et al. Acute kidney injury risk assessment: differences and similarities between resource-limited and resource-rich countries. Kidney Int. Rep.2 (4), 519\u2013529 (2017).","journal-title":"Kidney Int. Rep."},{"key":"74177_CR28","doi-asserted-by":"crossref","unstructured":"Angus, D. C., Kelley, M. A., Schmitz, R. J., White, A. & Popovich, J. Jr. Caring for the critically ill patient. Current and projected workforce requirements for care of the critically ill and patients with pulmonary disease: can we meet the requirements of an aging population? JAMA284 (21), 2762\u20132770 (2000).","DOI":"10.1001\/jama.284.21.2762"},{"issue":"2","key":"74177_CR29","doi-asserted-by":"publisher","first-page":"158","DOI":"10.4045\/tidsskr.10.34549","volume":"130","author":"JH Laake","year":"2010","unstructured":"Laake, J. H. & Bugge, J. F. [Acute renal failure in critically ill patients]. Tidsskr nor. Laegeforen130 (2), 158\u2013161 (2010).","journal-title":"Tidsskr nor. Laegeforen"},{"issue":"4","key":"74177_CR30","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1590\/S0103-507X2012000400005","volume":"24","author":"A Rhodes","year":"2012","unstructured":"Rhodes, A. & Moreno, R. P. Intensive care provision: a global problem. Rev. Bras. Ter. Intensiva24 (4), 322\u2013325 (2012).","journal-title":"Rev. Bras. Ter. Intensiva"},{"key":"74177_CR31","unstructured":"Associa\u00e7\u00e3o de Medicina Intensiva Brasileira, Censo, A. M. I. B. & Brazil.  https:\/\/www.amib.org.br\/censo-amid (Assessed 22 December 2022) (2016)."},{"issue":"9749","key":"74177_CR32","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1016\/S0140-6736(10)60446-1","volume":"376","author":"NK Adhikari","year":"2010","unstructured":"Adhikari, N. K., Fowler, R. A., Bhagwanjee, S. & Rubenfeld, G. D. Critical care and the global burden of critical illness in adults. Lancet376 (9749), 1339\u20131346 (2010).","journal-title":"Lancet"},{"issue":"21","key":"74177_CR33","doi-asserted-by":"publisher","first-page":"2323","DOI":"10.1001\/jama.2009.1754","volume":"302","author":"JL Vincent","year":"2009","unstructured":"Vincent, J. L. et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA302 (21), 2323\u20132329 (2009).","journal-title":"JAMA"},{"key":"74177_CR34","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1093\/ndt\/gfz087","volume":"35","author":"N Srisawat","year":"2020","unstructured":"Srisawat, N. et al. The epidemiology and characteristics of acute kidney injury in the Southeast Asia intensive care unit: a prospective multicentre study. Nephrol. Dial. Transpl.35, 1729\u20131738 (2020).","journal-title":"Nephrol. Dial. Transpl."},{"issue":"2","key":"74177_CR35","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1590\/2175-8239-jbn-2018-0178","volume":"41","author":"FS Thom\u00e9","year":"2019","unstructured":"Thom\u00e9, F. S., Sesso, R. C., Lopes, A. A., Lugon, J. R. & Martins, C. T. Brazilian chronic dialysis survey 2017. Braz. J. Nephrol.41 (2), 208\u2013214 (2019).","journal-title":"Braz. J. Nephrol."},{"issue":"6","key":"74177_CR36","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/S0002-9343(02)01230-5","volume":"113","author":"RL Mehta","year":"2002","unstructured":"Mehta, R. L. et al. Nephrology consultation in acute renal failure: does timing matter? Am. J. Med.113 (6), 456\u2013461 (2002).","journal-title":"J. Med."},{"issue":"1","key":"74177_CR37","first-page":"01","volume":"5","author":"ND Almeida","year":"2013","unstructured":"Almeida, N. D. & Pernambuco, U. F. D. A sa\u00fade no Brasil, impasses e desafios enfrentados pelo Sistema \u00danico De Sa\u00fade: SUS. Ver. Psicol. Sa\u00fade5 (1), 01\u20139 (2013).","journal-title":"Psicol. Sa\u00fade"},{"issue":"4","key":"74177_CR38","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.semnephrol.2008.04.001","volume":"28","author":"R Lombardi","year":"2008","unstructured":"Lombardi, R., Yu, L., Younes-Ibrahim, M., Schor, N. & Burdmann, E. A. Epidemiology of acute kidney injury in Latin America. Semin. Nephrol.28 (4), 320\u2013329 (2008).","journal-title":"Semin. Nephrol."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-74177-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-74177-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-74177-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T02:07:27Z","timestamp":1727921247000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-74177-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,3]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["74177"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-74177-y","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3481663\/v1","asserted-by":"object"}]},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,3]]},"assertion":[{"value":"23 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This project was approved by the ethics committees of the hospitals involved in this study, as well as the Ethics Committee of the University of S\u00e3o Paulo and the Federal University of Acre (process number 721.845). All patients or their responsible relatives signed an informed consent form and agreed to participate.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}],"article-number":"22954"}}