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This study aims to further investigate RC correspondence with standard tests in glaucoma, namely standard automated perimetry (SAP) and optical coherence tomography (OCT) within 10\u00b0 of visual field (VF). For this purpose, we included 41 participants, [21 glaucoma (GLA, mean age: 65.9\u2009\u00b1\u200912.4; 12 preperimetric eyes and 11 with VF defects) and 20 healthy controls (HC; mean age: 65.0\u2009\u00b1\u200910.3); 20 eyes]. At first, we compared the rate of detection\/exclusion of VF defects in RC vs. SAP. Then, for those with VF defects (11 eyes), we investigated the 68-pointwise correspondence of 10\u2009\u2212\u20092 layout of RC and SAP. For functional and structural (SF) correspondence, pointwise correspondence of RC, SAP vs. OCT<jats:sub>macula<\/jats:sub> [ macular ganglion cell thickness (GCL)] was also performed. Further, we compared sector-based correspondence of RC, SAP vs. OCT<jats:sub>macula<\/jats:sub> accounting for GCL displacement at the fovea as well as sector-based correspondence with OCT<jats:sub>disc<\/jats:sub> [peripapillary retinal nerve fiber layer thickness (pRNFL)]. Agreement estimates were reported along with Cohen Kappa (<jats:inline-formula><jats:tex-math>$$\\:\\kappa\\:$$<\/jats:tex-math><\/jats:inline-formula>) statistic. For overall performance, RC and SAP showed 100% agreement (<jats:inline-formula><jats:tex-math>$$\\:\\kappa\\:=1$$<\/jats:tex-math><\/jats:inline-formula>) for the exclusion of VF defects (HC and preperimetric GLA) and for detection of VF defects [11 eyes of 9 GLA, (<jats:inline-formula><jats:tex-math>$$\\:\\kappa\\:=1)$$<\/jats:tex-math><\/jats:inline-formula>]. Further, RC outperformed SAP in detection of arcuate scotomas, 7 vs. 5, respectively. Pointwise correspondence of VF defects (11 eyes), RC-SAP agreement reached 90% accuracy (<jats:inline-formula><jats:tex-math>$$\\:\\kappa\\:=0.77,\\:substantial\\:agreement$$<\/jats:tex-math><\/jats:inline-formula>). For SF correspondence, RC [SAP] showed 62% [69%] pointwise agreement with OCT<jats:sub>macula<\/jats:sub>, (<jats:inline-formula><jats:tex-math>$$\\:\\kappa\\:=0.10\\:\\left[0.33\\right]$$<\/jats:tex-math><\/jats:inline-formula>). For macular sector-based correspondence, SF correspondence improved and reached 83% [83%] agreement, (<jats:inline-formula><jats:tex-math>$$\\:\\kappa\\:=0.57\\:\\left[0.57\\right]$$<\/jats:tex-math><\/jats:inline-formula>). For OCT<jats:sub>disc<\/jats:sub> sector-based analysis, SF correspondence was highest, 100% [100%] agreement, (<jats:inline-formula><jats:tex-math>$$\\:\\kappa\\:=1\\:\\left[1\\right]$$<\/jats:tex-math><\/jats:inline-formula>). Rapid Campimetry gave reproducible results in comparison to SAP and OCT with high potential as a screening VF method given its short testing duration, ~\u20091\u00a0min in screening mode, and compatibility with telemedicine technologies upon future optimization and automation.<\/jats:p>","DOI":"10.1038\/s41598-024-75037-5","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T14:02:32Z","timestamp":1729864952000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Rapid Campimetry in glaucoma \u2013 correspondence with standard perimetry and OCT"],"prefix":"10.1038","volume":"14","author":[{"given":"Nidele","family":"Djouoma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francie H.","family":"Stolle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedrich","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hagen","family":"Thieme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaldoon O.","family":"Al-Nosairy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,25]]},"reference":[{"issue":"3","key":"75037_CR1","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/BF02721215","volume":"15","author":"A von Graefe","year":"1869","unstructured":"von Graefe, A. 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There was no rule of the funders in planning, conducting or reporting the current study. Other Authors None.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"25400"}}