{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:07:36Z","timestamp":1767650856525,"version":"3.28.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T00:00:00Z","timestamp":1730764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T00:00:00Z","timestamp":1730764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Ministry of Health and Welfare in Korea","award":["HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500"],"award-info":[{"award-number":["HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500","HI22C189500"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-76476-w","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T11:04:06Z","timestamp":1730804646000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bacterial contamination of autologous blood salvaged during deceased donor liver transplantation: a prospective observational study"],"prefix":"10.1038","volume":"14","author":[{"given":"Doyeon","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sangbin","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju Dong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-Hye","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyu-Sung","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Man","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoon Joo","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chisong","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin S.","family":"Ko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Sook","family":"Gwak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Won","family":"Joh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaab Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"key":"76476_CR1","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/s0140-6736(07)61197-0","volume":"370","author":"HG Klein","year":"2007","unstructured":"Klein, H. G., Spahn, D. R. & Carson, J. L. Red blood cell transfusion in clinical practice. Lancet. 370, 415\u2013426. https:\/\/doi.org\/10.1016\/s0140-6736(07)61197-0 (2007).","journal-title":"Lancet"},{"key":"76476_CR2","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1093\/bja\/aeq244","volume":"105","author":"A Ashworth","year":"2010","unstructured":"Ashworth, A. & Klein, A. A. Cell salvage as part of a blood conservation strategy in anaesthesia. Br. J. Anaesth. 105, 401\u2013416. https:\/\/doi.org\/10.1093\/bja\/aeq244 (2010).","journal-title":"Br. J. Anaesth."},{"key":"76476_CR3","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1002\/lt.26525","volume":"28","author":"D Kim","year":"2022","unstructured":"Kim, D. et al. Bile duct anastomosis does not promote bacterial contamination of autologous blood salvaged during living donor liver transplantation. Liver Transpl. 28, 1747\u20131755. https:\/\/doi.org\/10.1002\/lt.26525 (2022).","journal-title":"Liver Transpl."},{"key":"76476_CR4","first-page":"486","volume":"30","author":"A Alexopoulou","year":"2017","unstructured":"Alexopoulou, A., Agiasotelli, D., Vasilieva, L. E. & Dourakis, S. P. Bacterial translocation markers in liver cirrhosis. Annals Gastroenterol. 30, 486 (2017).","journal-title":"Annals Gastroenterol."},{"key":"76476_CR5","doi-asserted-by":"publisher","first-page":"4814","DOI":"10.3748\/wjg.v25.i33.4814","volume":"25","author":"A Nicoletti","year":"2019","unstructured":"Nicoletti, A. et al. Intestinal permeability in the pathogenesis of liver damage: from non-alcoholic fatty liver disease to liver transplantation. World J. Gastroenterol. 25, 4814\u20134834. https:\/\/doi.org\/10.3748\/wjg.v25.i33.4814 (2019).","journal-title":"World J. Gastroenterol."},{"key":"76476_CR6","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3109\/08820139509062765","volume":"24","author":"W Dzik","year":"1995","unstructured":"Dzik, W. Use of leukodepletion filters for the removal of bacteria. Immunol. Invest. 24, 95\u2013115. https:\/\/doi.org\/10.3109\/08820139509062765 (1995).","journal-title":"Immunol. Invest."},{"key":"76476_CR7","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1097\/sla.0000000000001486","volume":"264","author":"S Han","year":"2016","unstructured":"Han, S. et al. Safety of the use of blood salvage and Autotransfusion during Liver Transplantation for Hepatocellular Carcinoma. Ann. Surg. 264, 339\u2013343. https:\/\/doi.org\/10.1097\/sla.0000000000001486 (2016).","journal-title":"Ann. Surg."},{"key":"76476_CR8","doi-asserted-by":"publisher","first-page":"e842","DOI":"10.1097\/SLA.0000000000004866","volume":"276","author":"JH Kwon","year":"2022","unstructured":"Kwon, J. H. et al. Blood salvage and autotransfusion with single leukoreduction does not increase the risk of tumor recurrence after liver transplantation for advanced hepatocellular carcinoma. Ann. Surg. 276, e842\u2013e850. https:\/\/doi.org\/10.1097\/SLA.0000000000004866 (2022).","journal-title":"Ann. Surg."},{"key":"76476_CR9","doi-asserted-by":"publisher","first-page":"e0127981","DOI":"10.1371\/journal.pone.0127981","volume":"10","author":"S Han","year":"2015","unstructured":"Han, S. et al. Bioreactance is not interchangeable with thermodilution for measuring cardiac output during adult liver transplantation. PloS One. 10, e0127981. https:\/\/doi.org\/10.1371\/journal.pone.0127981 (2015).","journal-title":"PloS One"},{"key":"76476_CR10","doi-asserted-by":"publisher","first-page":"e552","DOI":"10.1097\/ccm.0000000000002306","volume":"45","author":"SY Cho","year":"2017","unstructured":"Cho, S. Y. et al. Impact of targeted interventions on trends in Central Line-Associated Bloodstream infection: a single-center experience from the Republic of Korea. Crit. Care Med. 45, e552\u2013e558. https:\/\/doi.org\/10.1097\/ccm.0000000000002306 (2017).","journal-title":"Crit. Care Med."},{"key":"76476_CR11","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.jhin.2015.12.012","volume":"92","author":"JY Choi","year":"2016","unstructured":"Choi, J. Y. et al. Trends in the distribution and antimicrobial susceptibility of causative pathogens of device-associated infection in Korean intensive care units from 2006 to 2013: results from the Korean nosocomial infections Surveillance System (KONIS). J. Hosp. Infect. 92, 363\u2013371. https:\/\/doi.org\/10.1016\/j.jhin.2015.12.012 (2016).","journal-title":"J. Hosp. Infect."},{"key":"76476_CR12","doi-asserted-by":"publisher","first-page":"2330","DOI":"10.1097\/01.brs.0000142436.14735.53","volume":"29","author":"MF Gruenberg","year":"2004","unstructured":"Gruenberg, M. F., Campaner, G. L., Sola, C. A. & Ortolan, E. G. Ultraclean air for prevention of postoperative infection after posterior spinal fusion with instrumentation: a comparison between surgeries performed with and without a vertical exponential filtered air-flow system. Spine (Phila Pa. 1976). 29, 2330\u20132334 (2004).","journal-title":"Spine (Phila Pa. 1976)"},{"key":"76476_CR13","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1097\/TP.0000000000002118","volume":"102","author":"KW Lee","year":"2018","unstructured":"Lee, K. W. et al. Higher risk of posttransplant liver graft failure in male recipients of female donor grafts might not be due to anastomotic size disparity. Transplantation. 102, 1115\u20131123. https:\/\/doi.org\/10.1097\/TP.0000000000002118 (2018).","journal-title":"Transplantation"},{"key":"76476_CR14","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1097\/SLA.0000000000001526","volume":"264","author":"S Han","year":"2016","unstructured":"Han, S. et al. Association between intraoperative platelet transfusion and early graft regeneration in living donor liver transplantation. Ann. Surg. 264, 1065\u20131072. https:\/\/doi.org\/10.1097\/SLA.0000000000001526 (2016).","journal-title":"Ann. Surg."},{"key":"76476_CR15","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1097\/TP.0000000000003265","volume":"105","author":"JH Kwon","year":"2021","unstructured":"Kwon, J. H. et al. Decrease in the risk of posttransplant hepatocellular carcinoma recurrence after the conversion to prestorage leukoreduction for transfused red blood cells. Transplantation. 105, 577\u2013585. https:\/\/doi.org\/10.1097\/TP.0000000000003265 (2021).","journal-title":"Transplantation"},{"key":"76476_CR16","first-page":"1","volume":"6","author":"R Hill","year":"1998","unstructured":"Hill, R. What sample size is enough in internet survey research. Interpers. Comput. Technology: Electron. J. 21st Century. 6, 1\u201310 (1998).","journal-title":"Interpers. Comput. Technology: Electron. J. 21st Century"},{"key":"76476_CR17","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1002\/bjs.1800740121","volume":"74","author":"DH Johnston","year":"1987","unstructured":"Johnston, D. H., Fairclough, J. A., Brown, E. M. & Morris, R. Rate of bacterial recolonization of the skin after preparation: four methods compared. Br. J. Surg. 74, 64. https:\/\/doi.org\/10.1002\/bjs.1800740121 (1987).","journal-title":"Br. J. Surg."},{"key":"76476_CR18","doi-asserted-by":"publisher","first-page":"e0235359","DOI":"10.1371\/journal.pone.0235359","volume":"15","author":"FR Ponziani","year":"2020","unstructured":"Ponziani, F. R. et al. Effect of liver transplantation on intestinal permeability and correlation with infection episodes. PLoS One. 15, e0235359. https:\/\/doi.org\/10.1371\/journal.pone.0235359 (2020).","journal-title":"PLoS One"},{"key":"76476_CR19","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1111\/1348-0421.12785","volume":"64","author":"Z Jafarpour","year":"2020","unstructured":"Jafarpour, Z., Pouladfar, G., Malek Hosseini, S. A., Firoozifar, M. & Jafari, P. Bacterial infections in the early period after liver transplantation in adults: a prospective single-center cohort study. Microbiol. Immunol. 64, 407\u2013415. https:\/\/doi.org\/10.1111\/1348-0421.12785 (2020).","journal-title":"Microbiol. Immunol."},{"key":"76476_CR20","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1034\/j.1600-0528.2002.017407.x","volume":"174","author":"LP Cousens","year":"2000","unstructured":"Cousens, L. P. & Wing, E. J. Innate defenses in the liver during Listeria infection. Immunol. Rev. 174, 150\u2013159. https:\/\/doi.org\/10.1034\/j.1600-0528.2002.017407.x (2000).","journal-title":"Immunol. Rev."},{"key":"76476_CR21","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1002\/lt.22278","volume":"17","author":"H Nafady-Hego","year":"2011","unstructured":"Nafady-Hego, H., Elgendy, H., Moghazy, W. E., Fukuda, K. & Uemoto, S. Pattern of bacterial and fungal infections in the first 3 months after pediatric living donor liver transplantation: an 11-year single-center experience. Liver Transpl. 17, 976\u2013984. https:\/\/doi.org\/10.1002\/lt.22278 (2011).","journal-title":"Liver Transpl."},{"key":"76476_CR22","doi-asserted-by":"publisher","unstructured":"Wi\u00dfmann, J. et al. (ed, E.) Persistence of pathogens on Inanimate surfaces: a narrative review. Microorganisms 9 https:\/\/doi.org\/10.3390\/microorganisms9020343 (2021).","DOI":"10.3390\/microorganisms9020343"},{"key":"76476_CR23","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1002\/lt.20214","volume":"10","author":"N Singh","year":"2004","unstructured":"Singh, N. et al. Bacteremias in liver transplant recipients: shift toward gram-negative bacteria as predominant pathogens. Liver Transpl. 10, 844\u2013849. https:\/\/doi.org\/10.1002\/lt.20214 (2004).","journal-title":"Liver Transpl."},{"key":"76476_CR24","doi-asserted-by":"publisher","first-page":"112","DOI":"10.3349\/ymj.2009.50.1.112","volume":"50","author":"SI Kim","year":"2009","unstructured":"Kim, S. I. et al. Epidemiology and risk factors for bacteremia in 144 consecutive living-donor liver transplant recipients. Yonsei Med. J. 50, 112\u2013121. https:\/\/doi.org\/10.3349\/ymj.2009.50.1.112 (2009).","journal-title":"Yonsei Med. J."},{"key":"76476_CR25","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1002\/lt.22165","volume":"16","author":"T Iida","year":"2010","unstructured":"Iida, T. et al. Posttransplant bacteremia in adult living donor liver transplant recipients. Liver Transpl. 16, 1379\u20131385. https:\/\/doi.org\/10.1002\/lt.22165 (2010).","journal-title":"Liver Transpl."},{"key":"76476_CR26","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1002\/lt.500060112","volume":"6","author":"N Singh","year":"2000","unstructured":"Singh, N., Paterson, D. L., Gayowski, T., Wagener, M. M. & Marino, I. R. Predicting bacteremia and bacteremic mortality in liver transplant recipients. Liver Transpl. 6, 54\u201361. https:\/\/doi.org\/10.1002\/lt.500060112 (2000).","journal-title":"Liver Transpl."},{"key":"76476_CR27","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1002\/lt.20346","volume":"11","author":"MS Gwak","year":"2005","unstructured":"Gwak, M. S. et al. Can a leukocyte depletion filter (LDF) reduce the risk of reintroduction of hepatocellular carcinoma cells? Liver Transpl. 11, 331\u2013335. https:\/\/doi.org\/10.1002\/lt.20346 (2005).","journal-title":"Liver Transpl."},{"key":"76476_CR28","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1097\/00000542-200309000-00021","volume":"99","author":"JH Waters","year":"2003","unstructured":"Waters, J. H., Hobson, T. M. & Procop, D. F. Bacterial reduction by cell salvage washing and leukocyte depletion filtration. Anesthesiology. 99, 652\u2013655 (2003).","journal-title":"Anesthesiology"},{"key":"76476_CR29","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1046\/j.1537-2995.1993.33293158045.x","volume":"33","author":"AJ Callaerts","year":"1993","unstructured":"Callaerts, A. J., Gielis, M. L., Sprengers, E. D. & Muylle, L. The mechanism of white cell reduction by synthetic fiber cell filters. Transfusion. 33, 134\u2013138 (1993).","journal-title":"Transfusion"},{"key":"76476_CR30","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1111\/j.1399-6576.1996.tb04397.x","volume":"40","author":"UE Kongsgaard","year":"1996","unstructured":"Kongsgaard, U. E., Wang, M. Y. & Kvalheim, G. Leucocyte depletion filter removes cancer cells in human blood. Acta Anaesthesiol. Scand. 40, 118\u2013120 (1996).","journal-title":"Acta Anaesthesiol. Scand."},{"key":"76476_CR31","doi-asserted-by":"publisher","unstructured":"Pinzone, M. R., Celesia, B. M., Di Rosa, M., Cacopardo, B. & Nunnari, G. Microbial translocation in chronic liver diseases. Int J Microbiol 694629, doi: (2012). https:\/\/doi.org\/10.1155\/2012\/694629 (2012).","DOI":"10.1155\/2012\/694629"},{"key":"76476_CR32","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/s1521-6918(03)00024-6","volume":"17","author":"R Wiest","year":"2003","unstructured":"Wiest, R. & Rath, H. C. Gastrointestinal disorders of the critically ill. Bacterial translocation in the gut. Best Pract. Res. Clin. Gastroenterol. 17, 397\u2013425. https:\/\/doi.org\/10.1016\/s1521-6918(03)00024-6 (2003).","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"key":"76476_CR33","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/S0016-5085(19)33249-4","volume":"63","author":"ND Finlayson","year":"1972","unstructured":"Finlayson, N. D., Krohn, K., Fauconnet, M. H. & Anderson, K. E. Significance of serum complement levels in chronic liver disease. Gastroenterology. 63, 653\u2013659 (1972).","journal-title":"Gastroenterology"},{"key":"76476_CR34","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1001\/archsurg.1996.01430230047009","volume":"131","author":"SM Swoboda","year":"1996","unstructured":"Swoboda, S. M., Merz, C., Kostuik, J., Trentler, B. & Lipsett, P. A. Does intraoperative blood loss affect antibiotic serum and tissue concentrations? Arch. Surg. 131, 1165\u20131171. https:\/\/doi.org\/10.1001\/archsurg.1996.01430230047009 (1996). discussion 1171\u2009\u2013\u20091162.","journal-title":"Arch. Surg."},{"key":"76476_CR35","doi-asserted-by":"publisher","first-page":"e0229724","DOI":"10.1371\/journal.pone.0229724","volume":"15","author":"S Chun","year":"2020","unstructured":"Chun, S. et al. Double-filtered leukoreduction as a method for risk reduction of transfusion-associated graft-versus-host disease. PLoS One. 15, e0229724. https:\/\/doi.org\/10.1371\/journal.pone.0229724 (2020).","journal-title":"PLoS One"},{"key":"76476_CR36","doi-asserted-by":"publisher","unstructured":"Lasko, M. J., Conelius, A. M., Serrano, O. K., Nicolau, D. P. & Kuti, J. L. Impact of intraoperative cell salvage on concentrations of antibiotics used for Surgical Prophylaxis. Antimicrob. Agents Chemother. 64 https:\/\/doi.org\/10.1128\/aac.01725-20 (2020).","DOI":"10.1128\/aac.01725-20"},{"key":"76476_CR37","doi-asserted-by":"publisher","first-page":"421","DOI":"10.4161\/viru.21282","volume":"3","author":"BL Hollenbeck","year":"2012","unstructured":"Hollenbeck, B. L. & Rice, L. B. Intrinsic and acquired resistance mechanisms in enterococcus. Virulence. 3, 421\u2013433. https:\/\/doi.org\/10.4161\/viru.21282 (2012).","journal-title":"Virulence"},{"key":"76476_CR38","doi-asserted-by":"publisher","first-page":"1799654","DOI":"10.1080\/19490976.2020.1799654","volume":"12","author":"MJ Wallace","year":"2020","unstructured":"Wallace, M. J., Fishbein, S. R. S. & Dantas, G. Antimicrobial resistance in enteric bacteria: current state and next-generation solutions. Gut Microbes. 12, 1799654. https:\/\/doi.org\/10.1080\/19490976.2020.1799654 (2020).","journal-title":"Gut Microbes"},{"key":"76476_CR39","doi-asserted-by":"publisher","first-page":"6211","DOI":"10.3748\/wjg.v20.i20.6211","volume":"20","author":"SI Kim","year":"2014","unstructured":"Kim, S. I. Bacterial infection after liver transplantation. World J. Gastroenterol. 20, 6211\u20136220. https:\/\/doi.org\/10.3748\/wjg.v20.i20.6211 (2014).","journal-title":"World J. Gastroenterol."},{"key":"76476_CR40","doi-asserted-by":"publisher","first-page":"222","DOI":"10.4254\/wjh.v10.i2.222","volume":"10","author":"A Ferrarese","year":"2018","unstructured":"Ferrarese, A. et al. Management of bacterial infection in the liver transplant candidate. World J. Hepatol. 10, 222\u2013230. https:\/\/doi.org\/10.4254\/wjh.v10.i2.222 (2018).","journal-title":"World J. Hepatol."},{"key":"76476_CR41","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/SLA.0000000000002062","volume":"267","author":"S Han","year":"2018","unstructured":"Han, S. et al. Perioperative fresh red blood cell transfusion may negatively affect recipient survival after liver transplantation. Ann. Surg. 267, 346\u2013351. https:\/\/doi.org\/10.1097\/SLA.0000000000002062 (2018).","journal-title":"Ann. Surg."},{"key":"76476_CR42","doi-asserted-by":"publisher","first-page":"112","DOI":"10.4285\/jkstn.2019.33.4.112","volume":"33","author":"HS Ha","year":"2019","unstructured":"Ha, H. S. et al. Deceased donor liver transplantation under the Korean model for end-stage liver disease score-based liver allocation system: 2-year allocation results at a high-volume transplantation center. Korean J. Transpl. 33, 112\u2013117. https:\/\/doi.org\/10.4285\/jkstn.2019.33.4.112 (2019).","journal-title":"Korean J. Transpl."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-76476-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-76476-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-76476-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T15:02:42Z","timestamp":1731078162000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-76476-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,5]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["76476"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-76476-w","relation":{},"ISSN":["2045-2322"],"issn-type":[{"type":"electronic","value":"2045-2322"}],"subject":[],"published":{"date-parts":[[2024,11,5]]},"assertion":[{"value":"8 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"26785"}}