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The ear canal and epitympanic region might be an easy-to-assess, noninvasive site for the read-out of supra-aortic, cerebral temperature. This observational cohort study comparatively investigated in-ear temperature and different core body temperature (cBT) measurements during TTM\/TH for moderate hypothermic circulatory arrest (mHCA) in aortic arch surgery. In total 24 patients (mean age of 56.8\u2009\u00b1\u200917.5\u00a0years; six females) were measured using infrared-thermography of the epitympanic region (BT<jats:sub>tym<\/jats:sub>), thermistor-based measurements at the esophagus (BT<jats:sub>eso<\/jats:sub>; gold standard), at the ear canal (BT<jats:sub>ear<\/jats:sub>), at the nasopharynx (BT<jats:sub>nas<\/jats:sub>), in the bladder (BT<jats:sub>ves<\/jats:sub>), and in the rectum (BT<jats:sub>rec<\/jats:sub>). The data analysis comprised absolute agreement (AA), bias, intraclass correlation coefficient (ICC), and limit of agreement (LoA). The results revealed high AAs of BT<jats:sub>tym<\/jats:sub>, BT<jats:sub>ear<\/jats:sub>, BT<jats:sub>nas<\/jats:sub> in reference to BT<jats:sub>eso<\/jats:sub> (biases 0.3\u20130.6\u00a0\u00b0C), with also excellent ICCs\u2009&gt;\u20090.9. BT<jats:sub>ves<\/jats:sub> and BT<jats:sub>rec<\/jats:sub> showed lower AAs, higher biases of\u2009+\u20092.5\u00a0\u00b0C to 3.1\u00a0\u00b0C with moderate ICCs during mHCA. In the phases of rapid temperature changes, the biases and LoAs were higher throughout all BT measurements. Herein, BT<jats:sub>tym<\/jats:sub> performed best of all measurement sites. The study informs about the BT dynamics at different body sites during the mHCA procedure. It supports the approach of using minimally invasive in-ear techniques to estimate core body temperature in an intrahospital TTM\/TH setting of mHCA.<\/jats:p>","DOI":"10.1038\/s41598-024-77237-5","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T15:06:44Z","timestamp":1731337604000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Agreement of in-ear temperature to core body temperature measures during invasive whole-body cooling for hypothermic circulatory arrest in aortic arch surgery"],"prefix":"10.1038","volume":"14","author":[{"given":"Jonas","family":"Langenhorst","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Benkert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Peterss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Feuerecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana","family":"Scheiermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Scheiermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Witte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Benkert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Bayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Prueckner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Pichlmaier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Schniepp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"77237_CR1","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s13054-019-2721-1","volume":"24","author":"FS Taccone","year":"2020","unstructured":"Taccone, F. 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