{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:03:47Z","timestamp":1791979427451,"version":"4.4.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-83446-9","type":"journal-article","created":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T20:40:05Z","timestamp":1735591205000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Impact of major duodenal papilla morphology on the outcomes of primary needle-knife fistulotomy for deep biliary cannulation"],"prefix":"10.1038","volume":"14","author":[{"given":"Amir","family":"Sadeghi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0557-1278","authenticated-orcid":false,"given":"Erfan","family":"Arabpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reyhaneh","family":"Rastegar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samareh","family":"Omidvari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi Azizmohammad","family":"Looha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoumeh","family":"Keshavarzian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Reza","family":"Zali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,30]]},"reference":[{"key":"83446_CR1","doi-asserted-by":"publisher","first-page":"4019","DOI":"10.3748\/wjg.v25.i29.4019","volume":"25","author":"M Pekg\u00f6z","year":"2019","unstructured":"Pekg\u00f6z, M. Post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review for prevention and treatment. World J. Gastroenterol. 25, 4019\u20134042. https:\/\/doi.org\/10.3748\/wjg.v25.i29.4019 (2019).","journal-title":"World J. Gastroenterol."},{"key":"83446_CR2","first-page":"286","volume":"14","author":"SJ Morales","year":"2018","unstructured":"Morales, S. J., Sampath, K. & Gardner, T. B. A Review of Prevention of Post-ERCP Pancreatitis. Gastroenterol. Hepatol. (N Y). 14, 286\u2013292 (2018).","journal-title":"Gastroenterol. Hepatol. (N Y)"},{"key":"83446_CR3","doi-asserted-by":"publisher","unstructured":"Tse, F., Yuan, Y., Moayyedi, P. & Leontiadis, G. I. Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Cochrane Database Syst. Rev. 12 (Cd009662). https:\/\/doi.org\/10.1002\/14651858.CD009662.pub2 (2012).","DOI":"10.1002\/14651858.CD009662.pub2"},{"key":"83446_CR4","doi-asserted-by":"publisher","first-page":"5","DOI":"10.4253\/wjge.v11.i1.5","volume":"11","author":"R Berry","year":"2019","unstructured":"Berry, R., Han, J. Y. & Tabibian, J. H. Difficult biliary cannulation: Historical perspective, practical updates, and guide for the endoscopist. World J. Gastrointest. Endosc. 11, 5\u201321. https:\/\/doi.org\/10.4253\/wjge.v11.i1.5 (2019).","journal-title":"World J. Gastrointest. Endosc"},{"key":"83446_CR5","doi-asserted-by":"publisher","first-page":"6455","DOI":"10.1007\/s00464-020-08136-9","volume":"35","author":"R Mohamed","year":"2021","unstructured":"Mohamed, R. et al. Morphology of the major papilla predicts ERCP procedural outcomes and adverse events. Surg. Endosc. 35, 6455\u20136465. https:\/\/doi.org\/10.1007\/s00464-020-08136-9 (2021).","journal-title":"Surg. Endosc"},{"key":"83446_CR6","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.gie.2016.06.051","volume":"85","author":"V Chandrasekhara","year":"2017","unstructured":"Chandrasekhara, V. et al. Adverse events associated with ERCP. Gastrointest. Endosc. 85, 32\u201347. https:\/\/doi.org\/10.1016\/j.gie.2016.06.051 (2017).","journal-title":"Gastrointest. Endosc"},{"key":"83446_CR7","doi-asserted-by":"publisher","first-page":"175628482311559","DOI":"10.1177\/17562848231155984","volume":"16","author":"F de Borrelli","year":"2023","unstructured":"de Borrelli, F. et al. Prevention of post-ERCP pancreatitis: current strategies and novel perspectives. Therapeutic Adv. Gastroenterol. 16, 17562848231155984 (2023).","journal-title":"Therapeutic Adv. Gastroenterol."},{"key":"83446_CR8","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1055\/s-0032-1326640","volume":"45","author":"F Tse","year":"2013","unstructured":"Tse, F., Yuan, Y., Moayyedi, P. & Leontiadis, G. I. Guide wire-assisted cannulation for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis. Endoscopy 45, 605\u2013618. https:\/\/doi.org\/10.1055\/s-0032-1326640 (2013).","journal-title":"Endoscopy"},{"key":"83446_CR9","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1093\/jcag\/gwaa025","volume":"4","author":"K Hnaris","year":"2021","unstructured":"Hnaris, K., Taylor, C., Hookey, L. & Bechara, R. Fistulotomy-First Approach is Safe and Effective in Endoscopic Retrograde Cholangiography: Results of a Prospective Case Series. J. Can. Assoc. Gastroenterol. 4, 173\u2013178. https:\/\/doi.org\/10.1093\/jcag\/gwaa025 (2021).","journal-title":"J. Can. Assoc. Gastroenterol."},{"key":"83446_CR10","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1186\/s12876-020-01455-0","volume":"20","author":"PH Chen","year":"2020","unstructured":"Chen, P. H. et al. Duodenal major papilla morphology can affect biliary cannulation and complications during ERCP, an observational study. BMC Gastroenterol. 20, 310. https:\/\/doi.org\/10.1186\/s12876-020-01455-0 (2020).","journal-title":"BMC Gastroenterol."},{"key":"83446_CR11","doi-asserted-by":"publisher","first-page":"4166","DOI":"10.12998\/wjcc.v9.i17.4166","volume":"9","author":"SY Han","year":"2021","unstructured":"Han, S. Y. et al. Primary needle-knife fistulotomy for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: Importance of the endoscopist\u2019s expertise level. World J. Clin. Cases. 9, 4166\u20134177. https:\/\/doi.org\/10.12998\/wjcc.v9.i17.4166 (2021).","journal-title":"World J. Clin. Cases"},{"key":"83446_CR12","doi-asserted-by":"publisher","first-page":"7341","DOI":"10.1038\/s41598-024-57758-9","volume":"14","author":"E Tari","year":"2024","unstructured":"Tari, E. et al. Morphology of the papilla can predict procedural safety and efficacy of ERCP-a systematic review and meta-analysis. Sci. Rep. 14, 7341. https:\/\/doi.org\/10.1038\/s41598-024-57758-9 (2024).","journal-title":"Sci. Rep."},{"key":"83446_CR13","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1177\/2050640616674837","volume":"5","author":"E Haraldsson","year":"2017","unstructured":"Haraldsson, E. et al. Endoscopic classification of the papilla of Vater. Results of an inter-and intraobserver agreement study. United Eur. Gastroenterol. J. 5, 504\u2013510 (2017).","journal-title":"United Eur. Gastroenterol. J."},{"key":"83446_CR14","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1007\/s10620-021-06983-7","volume":"67","author":"QS Zhang","year":"2022","unstructured":"Zhang, Q. S., Xu, J. H., Dong, Z. Q., Gao, P. & Shen, Y. C. Success and Safety of Needle Knife Papillotomy and Fistulotomy Based on Papillary Anatomy: A Prospective Controlled Trial. Dig. Dis. Sci. 67, 1901\u20131909. https:\/\/doi.org\/10.1007\/s10620-021-06983-7 (2022).","journal-title":"Dig. Dis. Sci."},{"key":"83446_CR15","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1016\/j.gie.2014.11.018","volume":"81","author":"P Katsinelos","year":"2015","unstructured":"Katsinelos, P., Lazaraki, G., Chatzimavroudis, G., Zavos, C. & Kountouras, J. The endoscopic morphology of major papillae influences the selected precut technique for biliary access. Gastrointest. Endosc. 81, 1056. https:\/\/doi.org\/10.1016\/j.gie.2014.11.018 (2015).","journal-title":"Gastrointest. Endosc"},{"key":"83446_CR16","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1016\/j.gie.2010.12.036","volume":"73","author":"PB Cotton","year":"2011","unstructured":"Cotton, P. B. et al. Grading the complexity of endoscopic procedures: results of an ASGE working party. Gastrointest. Endosc. 73, 868\u2013874 (2011).","journal-title":"Gastrointest. Endosc."},{"key":"83446_CR17","doi-asserted-by":"publisher","first-page":"W32","DOI":"10.2214\/AJR.14.14056","volume":"205","author":"K Zhao","year":"2015","unstructured":"Zhao, K., Adam, S. Z., Keswani, R. N., Horowitz, J. M. & Miller, F. H. Acute pancreatitis: revised Atlanta classification and the role of cross-sectional imaging. Am. J. Roentgenol. 205, W32\u2013W41 (2015).","journal-title":"Am. J. Roentgenol."},{"key":"83446_CR18","doi-asserted-by":"publisher","first-page":"2850","DOI":"10.1111\/j.1572-0241.2007.01563.x","volume":"102","author":"LE Ferreira","year":"2007","unstructured":"Ferreira, L. E. & Baron, T. H. Post-sphincterotomy bleeding: who, what, when, and how. Official J. Am. Coll. Gastroenterology| ACG. 102, 2850\u20132858 (2007).","journal-title":"Official J. Am. Coll. Gastroenterology| ACG"},{"key":"83446_CR19","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1007\/s00534-006-1156-7","volume":"14","author":"K Wada","year":"2007","unstructured":"Wada, K. et al. Diagnostic criteria and severity assessment of acute cholangitis: Tokyo Guidelines. J. Hepato-Biliary-Pancreatic Surg. 14, 52\u201358 (2007).","journal-title":"J. Hepato-Biliary-Pancreatic Surg."},{"key":"83446_CR20","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1016\/j.gie.2021.11.038","volume":"95","author":"KJ Nass","year":"2022","unstructured":"Nass, K. J. et al. Novel classification for adverse events in GI endoscopy: the AGREE classification. Gastrointest. Endosc. 95, 1078\u20131085 (2022).","journal-title":"Gastrointest. Endosc."},{"key":"83446_CR21","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1159\/000515692","volume":"40","author":"J Schirra","year":"2022","unstructured":"Schirra, J. et al. Biliary cannulation in endoscopic retrograde cholangiography: how to tackle the difficult papilla. Dig. Dis. 40, 85\u201396 (2022).","journal-title":"Dig. Dis."},{"key":"83446_CR22","doi-asserted-by":"publisher","DOI":"10.14309\/ctg.0000000000000788","author":"A Sadeghi","year":"2024","unstructured":"Sadeghi, A. et al. Primary needle-knife fistulotomy versus standard transpapillary technique for cannulation of long-size papilla: a randomized clinical trial. Clin. Translational Gastroenterol. https:\/\/doi.org\/10.14309\/ctg.0000000000000788 (2024).","journal-title":"Clin. Translational Gastroenterol."},{"key":"83446_CR23","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/s0016-5107(04)02463-0","volume":"61","author":"ML Freeman","year":"2005","unstructured":"Freeman, M. L. & Guda, N. M. ERCP cannulation: a review of reported techniques. Gastrointest. Endosc. 61, 112\u2013125. https:\/\/doi.org\/10.1016\/s0016-5107(04)02463-0 (2005).","journal-title":"Gastrointest. Endosc"},{"key":"83446_CR24","doi-asserted-by":"publisher","first-page":"616","DOI":"10.14309\/ajg.0000000000000480","volume":"115","author":"SI Jang","year":"2020","unstructured":"Jang, S. I. et al. Primary Needle-Knife Fistulotomy Versus Conventional Cannulation Method in a High-Risk Cohort of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis. Am. J. Gastroenterol. 115, 616\u2013624. https:\/\/doi.org\/10.14309\/ajg.0000000000000480 (2020).","journal-title":"Am. J. Gastroenterol."},{"key":"83446_CR25","doi-asserted-by":"publisher","first-page":"16658","DOI":"10.1038\/s41598-021-96142-9","volume":"11","author":"J Canena","year":"2021","unstructured":"Canena, J. et al. Efficacy and safety of primary, early and late needle-knife fistulotomy for biliary access. Sci. Rep. 11, 16658. https:\/\/doi.org\/10.1038\/s41598-021-96142-9 (2021).","journal-title":"Sci. Rep."},{"key":"83446_CR26","doi-asserted-by":"crossref","unstructured":"Canard, J. M., Lennon, A. M., L\u00e9tard, J. C., Etienne, J. & Okolo, P. Endoscopic retrograde cholangiopancreatography. Gastrointestinal Endoscopy in Practice. Churchill Livingstone, London, p. 370-465 (2011).","DOI":"10.1016\/B978-0-7020-3128-1.00010-9"},{"key":"83446_CR27","doi-asserted-by":"publisher","unstructured":"Balan, G. G. et al. Anatomy of Major Duodenal Papilla Influences ERCP Outcomes and Complication Rates: A Single Center Prospective Study. J. Clin. Med. 9 https:\/\/doi.org\/10.3390\/jcm9061637 (2020).","DOI":"10.3390\/jcm9061637"},{"key":"83446_CR28","doi-asserted-by":"publisher","first-page":"216","DOI":"10.20524\/aog.2023.0775","volume":"36","author":"EL Estela","year":"2023","unstructured":"Estela, E. L. et al. Association between type of major duodenal papilla and difficult biliary cannulation at first endoscopic retrograde cholangiopancreatography in adults: a cross-sectional study with bootstrap method. Ann. Gastroenterol. 36, 216\u2013222. https:\/\/doi.org\/10.20524\/aog.2023.0775 (2023).","journal-title":"Ann. Gastroenterol."},{"key":"83446_CR29","doi-asserted-by":"publisher","first-page":"e71","DOI":"10.1097\/meg.0000000000002238","volume":"33","author":"HR Mutneja","year":"2021","unstructured":"Mutneja, H. R. et al. Efficacy and safety of primary needle-knife fistulotomy in biliary cannulation: a systematic review and meta-analysis. Eur. J. Gastroenterol. Hepatol. 33, e71\u2013e77. https:\/\/doi.org\/10.1097\/meg.0000000000002238 (2021).","journal-title":"Eur. J. Gastroenterol. Hepatol."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83446-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83446-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83446-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T15:41:17Z","timestamp":1735659677000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83446-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,30]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["83446"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-83446-9","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,30]]},"assertion":[{"value":"13 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"31949"}}