{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:33:54Z","timestamp":1783488834975,"version":"3.55.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Medical Science and Technology Research Fund of Guangdong Province","award":["A2022485"],"award-info":[{"award-number":["A2022485"]}]},{"name":"the Science and Technology Projects in Guangzhou","award":["202201020122"],"award-info":[{"award-number":["202201020122"]}]},{"name":"the Plan on enhancing scientific research in Guangzhou Medical University, Guangdong Municipal Department of Science and Technology, Municipal Schools (Institutes) Jointly Funded Project","award":["2023A03J0386"],"award-info":[{"award-number":["2023A03J0386"]}]},{"name":"Guangzhou Medical University for the First-class Professional Construction Project in 2022-Enhancement of Undergraduates\u2019 Scientific Researchand Innovation Ability Project","award":["02-408-2203-2059"],"award-info":[{"award-number":["02-408-2203-2059"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-024-83937-9","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T19:47:56Z","timestamp":1738007276000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A retrospective analysis on maternal and neonatal outcomes in pSS\/AITD pregnancies"],"prefix":"10.1038","volume":"15","author":[{"given":"Miaoguan","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taizhen","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoshi","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijuan","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siqi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naifeng","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyun","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaojie","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,27]]},"reference":[{"key":"83937_CR1","doi-asserted-by":"publisher","first-page":"42","DOI":"10.11604\/pamj.2023.46.42.36534","volume":"46","author":"M Jridi","year":"2023","unstructured":"Jridi, M., Cherif, Y., Derbal, S., Dahmen, F. B. & Abdallah, M. Pulmonary involvement in primary Sjogren\u2019s syndrome: contribution of the different means in the systematic investigation. Pan Afr. Med. J. 46, 42. https:\/\/doi.org\/10.11604\/pamj.2023.46.42.36534 (2023).","journal-title":"Pan Afr. Med. J."},{"key":"83937_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2022.152062","volume":"56","author":"B Ming","year":"2022","unstructured":"Ming, B., Zhu, Y., Zhong, J. & Dong, L. Immunopathogenesis of Sjogren\u2019s syndrome: Current state of DAMPs. Semin. Arthritis Rheum. 56, 152062 (2022).","journal-title":"Semin. Arthritis Rheum."},{"issue":"6","key":"83937_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2020.102529","volume":"19","author":"P Conigliaro","year":"2020","unstructured":"Conigliaro, P. et al. Autoimmune thyroid disorders and rheumatoid arthritis: A bidirectional interplay. Autoimmun. Rev. 19(6), 102529. https:\/\/doi.org\/10.1016\/j.autrev.2020.102529 (2020).","journal-title":"Autoimmun. Rev."},{"issue":"1","key":"83937_CR4","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1186\/s12884-020-03176-4","volume":"20","author":"N Yuan","year":"2020","unstructured":"Yuan, N. et al. Relationship between anti-thyroid peroxidase antibody positivity and pregnancy-related and fetal outcomes in Euthyroid women: a single-center cohort study. BMC Pregnancy Childbirth 20(1), 491. https:\/\/doi.org\/10.1186\/s12884-020-03176-4 (2020).","journal-title":"BMC Pregnancy Childbirth"},{"issue":"1","key":"83937_CR5","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/BF03347388","volume":"30","author":"R Negro","year":"2007","unstructured":"Negro, R. et al. Euthyroid women with autoimmune disease undergoing assisted reproduction technologies: the role of autoimmunity and thyroid function. J. Endocrinol. Investig. 30(1), 3\u20138. https:\/\/doi.org\/10.1007\/BF03347388 (2007).","journal-title":"J. Endocrinol. Investig."},{"issue":"1","key":"83937_CR6","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13331","volume":"85","author":"E Borodina","year":"2021","unstructured":"Borodina, E. et al. The pathogenic role of circulating Hashimoto\u2019s Thyroiditis-derived TPO-positive IgG on fetal loss in naive mice. Am. J. Reprod. Immunol. 85(1), e13331. https:\/\/doi.org\/10.1111\/aji.13331 (2021).","journal-title":"Am. J. Reprod. Immunol."},{"key":"83937_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24054705","author":"GK Safarian","year":"2023","unstructured":"Safarian, G. K. et al. Impact of antithyroperoxidase antibodies (anti-TPO) on ovarian reserve and early embryo development in assisted reproductive technology cycles. Int. J. Mol. Sci. https:\/\/doi.org\/10.3390\/ijms24054705 (2023).","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"83937_CR8","doi-asserted-by":"publisher","first-page":"272","DOI":"10.2174\/1573397118666220127105546","volume":"18","author":"M Giron-Pillado","year":"2022","unstructured":"Giron-Pillado, M. et al. Autoimmune thyroid disease in primary Sjogren\u2019s syndrome: real-life screening practice and clinical outcomes. Curr. Rheumatol. Rev. 18(3), 272\u2013277. https:\/\/doi.org\/10.2174\/1573397118666220127105546 (2022).","journal-title":"Curr. Rheumatol. Rev."},{"key":"83937_CR9","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X241261487","author":"G Yared","year":"2024","unstructured":"Yared, G. et al. Uterine sacrifice in obstetric emergencies case series: Complex cases of fetal distress, labor challenges, and life-saving interventions. SAGE Open Med. Case Rep. https:\/\/doi.org\/10.1177\/2050313X241261487 (2024).","journal-title":"SAGE Open Med. Case Rep."},{"issue":"1","key":"83937_CR10","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s12969-023-00802-1","volume":"21","author":"JW van Straalen","year":"2023","unstructured":"van Straalen, J. W. et al. Juvenile idiopathic arthritis patients with positive family history of autoimmune thyroid disease might benefit from serological screening: analysis of the international Pharmachild registry. Pediatr. Rheumatol .Online J. 21(1), 19. https:\/\/doi.org\/10.1186\/s12969-023-00802-1 (2023).","journal-title":"Pediatr. Rheumatol .Online J."},{"key":"83937_CR11","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58020194","author":"D Galusca","year":"2022","unstructured":"Galusca, D. et al. Vitamin D implications and effect of supplementation in endocrine disorders: autoimmune thyroid disorders (Hashimoto\u2019s disease and Grave\u2019s disease), diabetes mellitus and obesity. Medicina (Kaunas) https:\/\/doi.org\/10.3390\/medicina58020194 (2022).","journal-title":"Medicina (Kaunas)"},{"key":"83937_CR12","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242015442","author":"T Bogovic Crncic","year":"2023","unstructured":"Bogovic Crncic, T. et al. Innate immunity in autoimmune thyroid disease during pregnancy. Int. J. Mol. Sci. https:\/\/doi.org\/10.3390\/ijms242015442 (2023).","journal-title":"Int. J. Mol. Sci."},{"key":"83937_CR13","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24032440","author":"I Vaivode","year":"2023","unstructured":"Vaivode, I. et al. Stress-related immune response and selenium status in autoimmune thyroid disease patients. Int. J. Mol. Sci. https:\/\/doi.org\/10.3390\/ijms24032440 (2023).","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"83937_CR14","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1186\/s12884-018-2110-9","volume":"18","author":"D Wu","year":"2018","unstructured":"Wu, D. et al. Resistance to thyroid hormone beta in autoimmune thyroid disease: a case report and review of literature. BMC Pregnancy Childbirth 18(1), 468. https:\/\/doi.org\/10.1186\/s12884-018-2110-9 (2018).","journal-title":"BMC Pregnancy Childbirth"},{"issue":"2","key":"83937_CR15","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1530\/EJE-16-0548","volume":"176","author":"S Nazarpour","year":"2017","unstructured":"Nazarpour, S. et al. Effects of levothyroxine treatment on pregnancy outcomes in pregnant women with autoimmune thyroid disease. Eur. J. Endocrinol. 176(2), 253\u2013265. https:\/\/doi.org\/10.1530\/EJE-16-0548 (2017).","journal-title":"Eur. J. Endocrinol."},{"issue":"12","key":"83937_CR16","doi-asserted-by":"publisher","first-page":"2092","DOI":"10.1016\/j.ajhg.2023.11.002","volume":"110","author":"S Sun","year":"2023","unstructured":"Sun, S. et al. Identifying risk variants for embryo aneuploidy using ultra-low coverage whole-genome sequencing from preimplantation genetic testing. Am. J. Hum. Genet. 110(12), 2092\u20132102. https:\/\/doi.org\/10.1016\/j.ajhg.2023.11.002 (2023).","journal-title":"Am. J. Hum. Genet."},{"issue":"3","key":"83937_CR17","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.jaut.2012.05.008","volume":"39","author":"MJ Amador-Patarroyo","year":"2012","unstructured":"Amador-Patarroyo, M. J. et al. Sjogren\u2019s syndrome at the crossroad of polyautoimmunity. J. Autoimmun. 39(3), 199\u2013205. https:\/\/doi.org\/10.1016\/j.jaut.2012.05.008 (2012).","journal-title":"J. Autoimmun."},{"issue":"5","key":"83937_CR18","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1089\/thy.2018.0098","volume":"29","author":"H Grulet","year":"2019","unstructured":"Grulet, H. et al. Three consecutive pregnancies in a patient with chronic autoimmune thyroid disease associated with hypothyroidism and extremely high levels of anti-thyrotropin receptor antibodies. Thyroid 29(5), 743\u2013747. https:\/\/doi.org\/10.1089\/thy.2018.0098 (2019).","journal-title":"Thyroid"},{"issue":"2","key":"83937_CR19","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s00404-009-1105-1","volume":"281","author":"MT Sahu","year":"2010","unstructured":"Sahu, M. T., Das, V., Mittal, S., Agarwal, A. & Sahu, M. Overt and subclinical thyroid dysfunction among Indian pregnant women and its effect on maternal and fetal outcome. Arch. Gynecol. Obstet. 281(2), 215\u2013220. https:\/\/doi.org\/10.1007\/s00404-009-1105-1 (2010).","journal-title":"Arch. Gynecol. Obstet."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83937-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83937-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83937-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T19:48:04Z","timestamp":1738007284000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-024-83937-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,27]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["83937"],"URL":"https:\/\/doi.org\/10.1038\/s41598-024-83937-9","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,27]]},"assertion":[{"value":"7 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Ethical approval was obtained for this study from the Third Affiliated Hospital of Guangzhou Medical University (2024049). Informed consent was obtained from all subjects and\/or their legal guardian(s).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"3437"}}