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A retrospective analysis of 323 ESRD patients receiving hemodialysis over a ten-year period revealed significant differences in outcomes across the three groups. AVF patients experienced the shortest wound healing times and the highest dialysis efficacy, while the CVC group had the highest infection and reoperation rates. Although there were no significant differences in cardiac function or cause-specific mortality, AVF patients had the longest median survival time, followed by those in the CVC and AVG groups. These findings suggest that while AVF provides superior dialysis efficiency and survival outcomes with fewer complications, patient suitability and individual health conditions must be carefully considered when selecting the appropriate vascular access for hemodialysis.<\/jats:p>","DOI":"10.1038\/s41598-025-01602-1","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T03:41:00Z","timestamp":1747280460000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hemodialysis pathway types influence wound healing complications and survival in end-stage renal disease patients in a retrospective cohort study"],"prefix":"10.1038","volume":"15","author":[{"given":"Jie","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"1602_CR1","doi-asserted-by":"publisher","first-page":"258","DOI":"10.36290\/vnl.2021.072","volume":"67","author":"SD Sulkova","year":"2021","unstructured":"Sulkova, S. D., Pokorna, A., Safranek, R., Pavlikova, L. & Palicka, V. Bone disesase in end-stage kidney disease - renal and non-renal components. Vnitr Lek. 67, 258\u2013263 (2021).","journal-title":"Vnitr Lek"},{"key":"1602_CR2","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1177\/17085381211068685","volume":"31","author":"F Wang","year":"2023","unstructured":"Wang, F. et al. Inhibition of mitochondrial fission alters neo-intimal hyperplasia via PI3K\/Akt signaling in arteriovenous fistulas. Vascular 31, 533\u2013543. https:\/\/doi.org\/10.1177\/17085381211068685 (2023).","journal-title":"Vascular"},{"key":"1602_CR3","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/j.tem.2021.06.001","volume":"32","author":"M Lambie","year":"2021","unstructured":"Lambie, M. et al. Insulin resistance in cardiovascular disease, uremia, and peritoneal dialysis. Trends Endocrinol. 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Semin Nephrol. 43, 151396. https:\/\/doi.org\/10.1016\/j.semnephrol.2023.151396 (2023).","journal-title":"Semin Nephrol."},{"key":"1602_CR8","doi-asserted-by":"publisher","first-page":"14","DOI":"10.36290\/vnl.2020.111","volume":"66","author":"M Vorcak","year":"2020","unstructured":"Vorcak, M., Zelenak, K., Sykora, J., Jezikova, A. & Mokan, M. Hemodialysis vascular access dysfunction and its endovascular treatment. Vnitr Lek. 66, 14\u201318 (2020).","journal-title":"Vnitr Lek"},{"key":"1602_CR9","doi-asserted-by":"publisher","first-page":"2813","DOI":"10.1007\/s00268-020-05540-z","volume":"44","author":"T Hussain","year":"2020","unstructured":"Hussain, T. & Farooqui, F. Outcome of permanent vascular access with Vein = 2.2\u00a0mm in diameter<\/at. World J. Surg. 44, 2813\u20132818. https:\/\/doi.org\/10.1007\/s00268-020-05540-z (2020).","journal-title":"World J. 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All methods were carried out in accordance with relevant guidelines and regulations, including the Declaration of Helsinki and institutional policies. Written informed consent was obtained from all participants prior to their inclusion in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and Method Compliance"}}],"article-number":"16866"}}