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IDf, was constructed voxel-wise from cut-off values of D\u2032 and f\u2032. The cut-off values, the data of 105 malignant and 86 benign lesions and the ROIs were re-used. For visual assessment, IDf was displayed as two-colour b800 overlay with red representing \u201cmalignant\u201d and green \u201cbenign\u201d voxels. A lesion was rated as \u201cmalignant\u201d, if a red hot spot was found within translucent hyperintensity on b800, otherwise as \u201cbenign\u201d. Intraindividual comparison of quantitative analysis and visual assessment of IDf showed comparable accuracy, both to each other and to combined ROI-analysis of D\u2032 and f\u2032 maps (0.927 vs. 0.937, <jats:italic>p<\/jats:italic>\u2009=\u20090.157, and 0.921 vs. 0.937, <jats:italic>p<\/jats:italic>\u2009=\u20090.157, respectively). Thus, visual assessment of IDf can replace combined ROI analysis of D\u2032 and f\u2032 without loss in accuracy enabling a considerable facilitation in clinical routine.<\/jats:p>","DOI":"10.1038\/s41598-025-01984-2","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T16:04:46Z","timestamp":1747670686000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Combined diffusion and perfusion index maps from simplified intravoxel incoherent motion imaging enable visual assessment of breast lesions"],"prefix":"10.1038","volume":"15","author":[{"given":"Petra","family":"M\u00fcrtz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alois M.","family":"Sprinkart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Block","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian A.","family":"Luetkens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Attenberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus C.","family":"Pieper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"key":"1984_CR1","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/jmri.26908","volume":"52","author":"M Iima","year":"2020","unstructured":"Iima, M. et al. 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