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Informed consent was obtained from all subjects and\/or their legal guardian(s).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethical statement"}},{"value":"Animal experiments strictly adhered to the 3Rs principle and were approved by the Animal Research Ethics Committee of Chongqing Medical University. The whole study is reported in accordance with ARRIVE guidelines.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal ethical statement"}}],"article-number":"23154"}}