{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:53:51Z","timestamp":1787003631747,"version":"build-2736575974"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:00:00Z","timestamp":1748908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:00:00Z","timestamp":1748908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-04816-5","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T14:28:00Z","timestamp":1748960880000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A clinical study on the preservation of pulp sensitivity in affected teeth with jaw cysts using concentrated growth factor: a retrospective Cross-sectional study"],"prefix":"10.1038","volume":"15","author":[{"given":"Wenjie","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanqing","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongzhen","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,3]]},"reference":[{"issue":"04","key":"4816_CR1","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1177\/003591577406700414","volume":"67","author":"IR Kramer","year":"1974","unstructured":"Kramer, I. R. Changing views on oral disease. J. R Soc. Med. 67 (04), 271\u2013276 (1974).","journal-title":"J. R Soc. Med."},{"key":"4816_CR2","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1007\/s00428-017-2182-3","volume":"472","author":"PM Speight","year":"2018","unstructured":"Speight, P. M. & Takata, T. New tumour entities in the 4th edition of the world health organization classification of head and neck tumours: odontogenic and maxillofacial bone tumours. Virchows Arch. 472, 331\u2013339 (2018).","journal-title":"Virchows Arch."},{"issue":"04","key":"4816_CR3","doi-asserted-by":"publisher","first-page":"328","DOI":"10.4103\/jispcd.JISPCD_180_19","volume":"9","author":"BF Nyimi","year":"2019","unstructured":"Nyimi, B. F., Yifang, Z. & Liu, B. The changing landscape in treatment of cystic lesions of the jaws. J. Int. Soc. Prev. Community Dent. 9 (04), 328\u2013337 (2019).","journal-title":"J. Int. Soc. Prev. Community Dent."},{"key":"4816_CR4","doi-asserted-by":"publisher","first-page":"5225","DOI":"10.2147\/IJGM.S431638","volume":"16","author":"A Li","year":"2023","unstructured":"Li, A. et al. Clinical effect of Platelet-Rich fibrin combined with BIO-GENE artificial bone meal in bone defects after jaw cyst surgery. Int. J. Gen. Med. 16, 5225\u20135234 (2023).","journal-title":"Int. J. Gen. Med."},{"issue":"01","key":"4816_CR5","doi-asserted-by":"publisher","first-page":"14155","DOI":"10.1038\/s41598-020-71029-3","volume":"10","author":"I Tsesis","year":"2020","unstructured":"Tsesis, I., Krepel, G., Koren, T., Rosen, E. & Kfir, A. Accuracy for diagnosis of periapical cystic lesions. Sci. Rep. 10 (01), 14155 (2020).","journal-title":"Sci. Rep."},{"issue":"09","key":"4816_CR6","doi-asserted-by":"publisher","first-page":"991","DOI":"10.3390\/medicina57090991","volume":"57","author":"R Schvartzman Cohen","year":"2021","unstructured":"Schvartzman Cohen, R. et al. The development of large radicular cysts in endodontically versus non-endodontically treated maxillary teeth. Medicina 57 (09), 991 (2021).","journal-title":"Medicina"},{"issue":"02","key":"4816_CR7","first-page":"239","volume":"8","author":"NS Kadam","year":"2014","unstructured":"Kadam, N. S., De Ataide, I. D. N., Raghava, P., Fernandes, M. & Hede, R. Management of large radicular cyst by Conservative surgical approach: a case report. J. Clin. Diagn. Res. 8 (02), 239\u2013241 (2014).","journal-title":"J. Clin. Diagn. Res."},{"issue":"01","key":"4816_CR8","doi-asserted-by":"publisher","first-page":"101305","DOI":"10.1016\/j.jormas.2022.10.004","volume":"124","author":"D Diarra","year":"2023","unstructured":"Diarra, D., Nyimi, B. F., Sun, R. & Zhao, J. The clinical importance of marsupialization treatment of the cystic lesion of the jaws: analysis of the dental pulp vitality. J. Stomatol. Oral Maxillofac. Surg. 124 (01), 101305 (2023).","journal-title":"J. Stomatol. Oral Maxillofac. Surg."},{"issue":"02","key":"4816_CR9","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1111\/j.1752-7325.2005.tb02792.x","volume":"65","author":"DJ Caplan","year":"2005","unstructured":"Caplan, D. J., Cai, J., Yin, G. & White, B. A. Root Canal filled versus non-root Canal filled teeth: a retrospective comparison of survival times. J. Public. Health Dent. 65 (02), 90\u201396 (2005).","journal-title":"J. Public. Health Dent."},{"issue":"01","key":"4816_CR10","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1365-263X.2008.00955.x","volume":"19","author":"V Gopikrishna","year":"2009","unstructured":"Gopikrishna, V., Pradeep, G. & Venkateshbabu, N. Assessment of pulp vitality: a review. Int. J. Paediatr. Dent. 19 (01), 3\u201315 (2009).","journal-title":"Int. J. Paediatr. Dent."},{"issue":"06","key":"4816_CR11","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.oooo.2016.01.015","volume":"121","author":"JF Cunha","year":"2016","unstructured":"Cunha, J. F. et al. Clinicopathologic features associated with recurrence of the odontogenic keratocyst: a cohort retrospective analysis. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 121 (06), 629\u2013635 (2016).","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol."},{"issue":"06","key":"4816_CR12","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.oooo.2017.06.121","volume":"124","author":"JT Rodrigues","year":"2017","unstructured":"Rodrigues, J. T., dos Santos Antunes, H., Armada, L. & Pires, F. R. Influence of surgical decompression on the expression of inflammatory and tissue repair biomarkers in periapical cysts. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 124 (06), 561\u2013567 (2017).","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol."},{"issue":"01","key":"4816_CR13","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1186\/s12903-021-01738-2","volume":"21","author":"A Elhakim","year":"2021","unstructured":"Elhakim, A., Kim, S., Kim, E. & Elshazli, A. H. Preserving the vitality of teeth adjacent to a large radicular cyst in periapical microsurgery: a case report with 4-year follow-up. BMC Oral Health. 21 (01), 382 (2021).","journal-title":"BMC Oral Health"},{"issue":"06","key":"4816_CR14","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/sj.bdj.2014.201","volume":"216","author":"AH Gluskin","year":"2014","unstructured":"Gluskin, A. H., Peters, C. I. & Peters, O. A. Minimally invasive endodontics: challenging prevailing paradigms. Br. Dent. J. 216 (06), 347\u2013353 (2014).","journal-title":"Br. Dent. J."},{"key":"4816_CR15","doi-asserted-by":"crossref","unstructured":"Gole\u017e, A., Ovsenik, M. & Cankar, K. The effect of orthodontic tooth movement on the sensitivity of dental pulp: a systematic review and meta-analysis. Heliyon 9(04), e14621 (2023).","DOI":"10.1016\/j.heliyon.2023.e14621"},{"issue":"02","key":"4816_CR16","first-page":"81","volume":"22","author":"ZHAO Yi","year":"2019","unstructured":"Yi, Z. H. A. O., Bing, L. I. U. & Yi Fang, Z. H. A. O. Controversies regarding the management of teeth associated with cystic lesions of the jaws. Chin. J. Dent. Res. 22 (02), 81 (2019).","journal-title":"Chin. J. Dent. Res."},{"key":"4816_CR17","doi-asserted-by":"crossref","unstructured":"Wang, Z. et al. Novel biomaterial strategies for controlled growth factor delivery for biomedical applications. NPG Asia Mater. 9(10), e435 (2017).","DOI":"10.1038\/am.2017.171"},{"issue":"08","key":"4816_CR18","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1002\/jemt.20968","volume":"74","author":"LF Rodella","year":"2011","unstructured":"Rodella, L. F. et al. Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fraction. Microsc Res. Tech. 74 (08), 772\u2013777 (2011).","journal-title":"Microsc Res. Tech."},{"issue":"06","key":"4816_CR19","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1002\/jbm.a.36906","volume":"108","author":"F Tabatabaei","year":"2020","unstructured":"Tabatabaei, F., Aghamohammadi, Z. & Tayebi, L. In vitro and in vivo effects of concentrated growth factor on cells and tissues. J. Biomed. Mater. Res. A. 108 (06), 1338\u20131350 (2020).","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"05","key":"4816_CR20","doi-asserted-by":"publisher","first-page":"635","DOI":"10.3390\/pharmaceutics13050635","volume":"13","author":"N Calabriso","year":"2021","unstructured":"Calabriso, N. et al. Angiogenic properties of concentrated growth factors (CGFs): the role of soluble factors and cellular components. Pharmaceutics 13 (05), 635 (2021).","journal-title":"Pharmaceutics"},{"issue":"12","key":"4816_CR21","doi-asserted-by":"publisher","first-page":"4563","DOI":"10.1073\/pnas.1221602110","volume":"110","author":"MM Martino","year":"2013","unstructured":"Martino, M. M., Briquez, P. S., Ranga, A., Lutolf, M. P. & Hubbell, J. A. Heparin-binding domain of fibrin (ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Proc. Natl. Acad. Sci. 110 (12), 4563\u20134568 (2013).","journal-title":"Proc. Natl. Acad. Sci."},{"key":"4816_CR22","doi-asserted-by":"publisher","first-page":"204173141881750","DOI":"10.1177\/2041731418817505","volume":"9","author":"R Jin","year":"2018","unstructured":"Jin, R. et al. Effects of concentrated growth factor on proliferation, migration, and differentiation of human dental pulp stem cells in vitro. J. Tissue Eng. 9, 2041731418817505 (2018).","journal-title":"J. Tissue Eng."},{"issue":"05","key":"4816_CR23","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1111\/j.1365-2842.2010.02160.x","volume":"38","author":"H Karayilmaz","year":"2011","unstructured":"Karayilmaz, H. & Kirzio\u011flu, Z. Comparison of the reliability of laser doppler flowmetry, pulse oximetry and electric pulp tester in assessing the pulp vitality of human teeth. J. Oral Rehabil. 38 (05), 340\u2013347 (2011).","journal-title":"J. Oral Rehabil"},{"issue":"05","key":"4816_CR24","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1111\/iej.13045","volume":"52","author":"S Hong","year":"2019","unstructured":"Hong, S., Li, L., Cai, W. & Jiang, B. The potential application of concentrated growth factor in regenerative endodontics. Int. Endod J. 52 (05), 646\u2013655 (2019).","journal-title":"Int. Endod J."},{"issue":"01","key":"4816_CR25","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1038\/s41598-023-50523-4","volume":"14","author":"G Niu","year":"2024","unstructured":"Niu, G. et al. A 3-year follow-up clinical study on the preservation for vitality of involved tooth in jaw cysts through an innovative method. Sci. Rep. 14 (01), 128 (2024).","journal-title":"Sci. Rep."},{"issue":"01","key":"4816_CR26","first-page":"96","volume":"8","author":"K Hee-Jin","year":"2023","unstructured":"Hee-Jin, K. & Kyung-San, M. Recovery of pulp sensibility after the surgical management of a large radicular cyst: A case report with a 4.5-year follow-up. Eur. Endod J. 8 (01), 96\u2013100 (2023).","journal-title":"Eur. Endod J."},{"issue":"05","key":"4816_CR27","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1111\/odi.12338","volume":"21","author":"YJ Liang","year":"2015","unstructured":"Liang, Y. J., He, W. J., Zheng, P. B. & Liao, G. Q. Inferior alveolar nerve function recovers after decompression of large mandibular cystic lesions. Oral Dis. 21 (05), 674\u2013678 (2015).","journal-title":"Oral Dis."},{"issue":"01","key":"4816_CR28","first-page":"1p10","volume":"29","author":"YF Zhao","year":"2019","unstructured":"Zhao, Y. F. & Liu, B. Contemporary strategies for managing tooth\/teeth associated with cystic lesions of the jaws. J. Oral Maxillofac. Surg. 29 (01), 1p10 (2019).","journal-title":"J. Oral Maxillofac. Surg."},{"issue":"04","key":"4816_CR29","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1016\/j.joms.2014.10.024","volume":"73","author":"DM Allon","year":"2015","unstructured":"Allon, D. M., Allon, I., Anavi, Y., Kaplan, I. & Chaushu, G. Decompression as a treatment of odontogenic cystic lesions in children. J. Oral Maxillofac. Surg. 73 (04), 649\u2013654 (2015).","journal-title":"J. Oral Maxillofac. Surg."},{"key":"4816_CR30","doi-asserted-by":"publisher","first-page":"S106","DOI":"10.4103\/0976-237X.152963","volume":"6","author":"RS de Molon","year":"2015","unstructured":"de Molon, R. S. et al. Five years follow-up of a keratocyst odontogenic tumor treated by marsupialization and enucleation: A case report and literature review. Contemp. Clin. Dent. 6, S106\u2013S110 (2015).","journal-title":"Contemp. Clin. Dent."},{"issue":"02","key":"4816_CR31","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1111\/aej.12381","volume":"46","author":"D Ricucci","year":"2020","unstructured":"Ricucci, D., Amantea, M., Girone, C. & Siqueira, J. F. Jr Atypically grown large periradicular cyst affecting adjacent teeth and leading to confounding diagnosis of non-endodontic pathology. Aust Endod J. 46 (02), 272\u2013281 (2020).","journal-title":"Aust Endod J."},{"key":"4816_CR32","unstructured":"Zhu, M. Clinical Effect Study of Retaining Living Pulp on the Margin of Jaw Cysts Involving Teeth (Dalian Medical University, 2021)."},{"issue":"05","key":"4816_CR33","doi-asserted-by":"publisher","first-page":"3487","DOI":"10.3892\/ol.2017.5905","volume":"13","author":"T Naruse","year":"2017","unstructured":"Naruse, T. et al. Histopathological and immunohistochemical study in keratocystic odontogenic tumors: predictive factors of recurrence. Oncol. Lett. 13 (05), 3487\u20133493 (2017).","journal-title":"Oncol. Lett."},{"key":"4816_CR34","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1007\/978-981-15-1346-6_27","volume-title":"Oral and Maxillofacial Surgery for the Clinician","author":"N Malik","year":"2021","unstructured":"Malik, N. Cysts of the oro-maxillofacial region. In Oral and Maxillofacial Surgery for the Clinician (eds Bonanthaya, K. et al.) 549\u2013575 (Springer, 2021)."},{"issue":"04","key":"4816_CR35","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1055\/s-0041-1741012","volume":"16","author":"Z Khurshid","year":"2022","unstructured":"Khurshid, Z., Alnaim, A. J. A., Alhashim, A. A. A. & Imran, E. Adanir, N. Future of decellularized dental pulp matrix in regenerative endodontics. Eur. J. Dent. 16 (04), 737\u2013741 (2022).","journal-title":"Eur. J. Dent."},{"key":"4816_CR36","first-page":"411","volume":"34","author":"YZ Liao","year":"2013","unstructured":"Liao, Y. Z., Liu, B. & Zhao, Y. F. Clinical assessment of the preservation of teeth involved in keratocystic odontogenic tumor. Med. J. Wuhan Univ. 34, 411\u2013414 (2013).","journal-title":"Med. J. Wuhan Univ."},{"issue":"04","key":"4816_CR37","doi-asserted-by":"publisher","first-page":"101892","DOI":"10.1016\/j.jormas.2024.101892","volume":"125","author":"D Shi","year":"2024","unstructured":"Shi, D., Dong, H., Chen, B., Zhu, Z. & Zhang, T. Decompression-first or direct enucleation: the choice of treatment for medium-sized odontogenic jaw cysts. J. Stomatol. Oral Maxillofac. Surg. 125 (04), 101892 (2024).","journal-title":"J. Stomatol. Oral Maxillofac. Surg."},{"issue":"01","key":"4816_CR38","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1055\/s-0034-1384738","volume":"8","author":"E Rubio","year":"2015","unstructured":"Rubio, E. & Mombr\u00fa, C. Spontaneous bone healing after cysts enucleation without bone grafting materials: a randomized clinical study. Craniomaxillofac. Trauma. Reconstr. 8 (01), 14\u201322 (2015).","journal-title":"Craniomaxillofac. Trauma. Reconstr."},{"issue":"03\u201304","key":"4816_CR39","doi-asserted-by":"publisher","first-page":"323","DOI":"10.3109\/00016356109043395","volume":"19","author":"BN \u00d6stby","year":"1961","unstructured":"\u00d6stby, B. N. The role of the blood clot in endodontic therapy an experimental histologic study. Acta Odontol. Scand. 19 (03\u201304), 323\u2013353 (1961).","journal-title":"Acta Odontol. Scand."},{"issue":"03","key":"4816_CR40","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.ijom.2010.11.016","volume":"40","author":"D Brajdi\u0107","year":"2011","unstructured":"Brajdi\u0107, D. et al. Evaluation of sensitivity of teeth after mandibular fractures. Int. J. Oral Maxillofac. Surg. 40 (03), 266\u2013270 (2011).","journal-title":"Int. J. Oral Maxillofac. Surg."},{"issue":"01","key":"4816_CR41","doi-asserted-by":"publisher","first-page":"14953","DOI":"10.1038\/s41598-022-16921-w","volume":"12","author":"JK Ku","year":"2022","unstructured":"Ku, J. K., Han, M., Yongvikul, A., Huh, J. K. & Kim, J. Y. Volumetric analysis of spontaneous bone healing after jaw cyst enucleation. Sci. Rep. 12 (01), 14953 (2022).","journal-title":"Sci. Rep."},{"issue":"18","key":"4816_CR42","doi-asserted-by":"publisher","first-page":"10534","DOI":"10.3390\/ijms231810534","volume":"23","author":"S Minic","year":"2022","unstructured":"Minic, S., Vital, S., Chaussain, C., Boukpessi, T. & Mangione, F. Tissue characteristics in endodontic regeneration: a systematic review. Int. J. Mol. Sci. 23 (18), 10534 (2022).","journal-title":"Int. J. Mol. Sci."},{"issue":"06","key":"4816_CR43","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/j.jormas.2018.06.001","volume":"119","author":"IO Sahin","year":"2018","unstructured":"Sahin, I. O., Gokmenoglu, C. & Kara, C. Effect of concentrated growth factor on osteoblast cell response. J. Stomatol. Oral Maxillofac. Surg. 119 (06), 477\u2013481 (2018).","journal-title":"J. Stomatol. Oral Maxillofac. Surg."},{"issue":"05\u201306","key":"4816_CR44","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1089\/ten.tea.2014.0058","volume":"21","author":"C Yuan","year":"2015","unstructured":"Yuan, C. et al. Coculture of stem cells from apical papilla and human umbilical vein endothelial cell under hypoxia increases the formation of three-dimensional vessel-like structures in vitro. Tissue Eng. Part. A. 21 (05\u201306), 1163\u20131172 (2015).","journal-title":"Tissue Eng. Part. A"},{"issue":"04","key":"4816_CR45","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1002\/jbm.b.33587","volume":"104","author":"H Dhillon","year":"2016","unstructured":"Dhillon, H., Kaushik, M. & Sharma, R. Regenerative endodontics\u2014creating new horizons. J. Biomed. Mater. Res. B. 104 (04), 676\u2013685 (2016).","journal-title":"J. Biomed. Mater. Res. B"},{"issue":"03","key":"4816_CR46","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.joen.2017.10.007","volume":"44","author":"Y Fang","year":"2018","unstructured":"Fang, Y. et al. Influence of apical diameter on the outcome of regenerative endodontic treatment in teeth with pulp necrosis: a review. J. Endod. 44 (03), 414\u2013431 (2018).","journal-title":"J. Endod"},{"issue":"10","key":"4816_CR47","doi-asserted-by":"publisher","first-page":"705","DOI":"10.14260\/jemds\/2021\/151","volume":"10","author":"A Behera","year":"2021","unstructured":"Behera, A., Santhanam, A., Sherlin, H. J., Jayaraj, G. & Don, K. R. Estimation of age using dimensions of apical foramina of teeth. J. Evol. Med. Dent. Sci. 10 (10), 705\u2013711 (2021).","journal-title":"J. Evol. Med. Dent. Sci."},{"issue":"08","key":"4816_CR48","doi-asserted-by":"publisher","first-page":"4667","DOI":"10.1007\/s00784-023-05093-0","volume":"27","author":"SG Alak","year":"2023","unstructured":"Alak, S. G., Kele\u015f, A., Keskin, C., Martins, J. N. & Versiani, M. A. Age-related changes in the morphology of the root Canal system of mandibular first molars: a micro-CT study. Clin. Oral Investig. 27 (08), 4667\u20134675 (2023).","journal-title":"Clin. Oral Investig"},{"issue":"06","key":"4816_CR49","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1097\/SCS.0000000000009300","volume":"34","author":"Y Lai","year":"2023","unstructured":"Lai, Y. et al. A comparative evaluation of Iliac crest cortical-cancellous bone blocks graft with and without concentrated growth factors (CGFs) in secondary alveolar bone grafting: a retrospective study. J. Craniofac. Surg. 34 (06), 1789\u20131794 (2023).","journal-title":"J. Craniofac. Surg."},{"key":"4816_CR50","doi-asserted-by":"crossref","unstructured":"Inchingolo, F. et al. Guided Bone Regeneration: CGF and PRF Combined With Various Types of Scaffolds\u2014A Systematic Review. Int. J. Dent. 4990295 (2024). (2024)(01).","DOI":"10.1155\/ijod\/4990295"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-04816-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-04816-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-04816-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T18:56:15Z","timestamp":1757184975000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-04816-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,3]]},"references-count":50,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4816"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-04816-5","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,3]]},"assertion":[{"value":"11 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2025","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original online version of this Article was revised: In this article Wenjie Zhou and Chuanqing Mao should have been denoted as equally contributing authors.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"19482"}}