{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T05:15:57Z","timestamp":1784178957232,"version":"3.55.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-05957-3","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T18:16:39Z","timestamp":1755627399000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Incidence and predictors of respiratory distress among neonates admitted to neonatal intensive care unit, Northwest Ethiopia"],"prefix":"10.1038","volume":"15","author":[{"given":"Dereje","family":"Woldeyes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayenew","family":"Negesse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alehegn Aderaw","family":"Alamneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selamawit Shita","family":"Jemberie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abateneh Addis","family":"Anteneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molla Yigzaw","family":"Birhanu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,19]]},"reference":[{"key":"5957_CR1","doi-asserted-by":"publisher","unstructured":"Sweet, L. R. et al. Respiratory distress in the neonate: Case definition & guidelines for data collection, analysis, and presentation of maternal immunization safety data. Vaccine [Internet]. 35 (48), 6506\u201317 Available from: https:\/\/doi.org\/10.1016\/j.vaccine.2017.01.046 (2017).","DOI":"10.1016\/j.vaccine.2017.01.046"},{"key":"5957_CR2","doi-asserted-by":"crossref","unstructured":"Reuter, S., Moser, C. & Baack, M. Respiratory Distress in the Newborn. Pediatr. Rev. [Internet]. 35 (10), 417 Available from: pmc\/articles\/PMC4533247\/ (2014).","DOI":"10.1542\/pir.35.10.417"},{"key":"5957_CR3","doi-asserted-by":"crossref","unstructured":"Edwards, M. O., Kotecha, S. J. S. & Kotecha, S. J. S. Respiratory Distress of the Term Newborn Infant. Paediatr. Respir. Rev. [Internet]. 14 (1), 29\u201337 (Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1526054212000073 2013).","DOI":"10.1016\/j.prrv.2012.02.002"},{"issue":"7","key":"5957_CR4","first-page":"771","volume":"65","author":"A Parkash","year":"2015","unstructured":"Parkash, A., Haider, N., Khoso, Z. A. & Shaikh, A. S. Frequency, causes and outcome of neonates with respiratory distress admitted to neonatal intensive care unit, National Institute of child health, Karachi. J. Pak Med. Assoc. 65 (7), 771\u2013775 (2015).","journal-title":"J. Pak Med. Assoc."},{"issue":"1","key":"5957_CR5","first-page":"1","volume":"24","author":"O Access","year":"2016","unstructured":"Access, O. et al. Neonatal respiratory distress in a reference neonatal unit in cameroon: an analysis of prevalence, predictors, etiologies and outcomes. Pan Afr. Med. J. 24 (1), 1\u201310 (2016).","journal-title":"Pan Afr. Med. J."},{"key":"5957_CR6","doi-asserted-by":"crossref","unstructured":"Sivanandan, S., Agarwal, R. & Sethi, A. Respiratory distress in term neonates in low-resource settings. In: Seminars in Fetal and Neonatal Medicine. Elsevier; 260\u2013266. (2017).","DOI":"10.1016\/j.siny.2017.04.004"},{"key":"5957_CR7","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/BF02823875","volume":"63","author":"A Kumar","year":"1996","unstructured":"Kumar, A. & Vishnu Bhat, B. Epidemiology of respiratory distress of newborns. Indian J. Pediatr. 63, 93\u201398 (1996).","journal-title":"Indian J. Pediatr."},{"issue":"2","key":"5957_CR8","doi-asserted-by":"publisher","first-page":"131","DOI":"10.3126\/jnhrc.v16i2.20297","volume":"16","author":"P Rijal","year":"2018","unstructured":"Rijal, P. & Shrestha, M. Scenario of Neonatal Respiratory Distress in Tertiary Hospital. J Nepal Health Res Counc [Internet] 16(2), 131\u20135. http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29983424 (2018).","journal-title":"J Nepal Health Res Counc [Internet]"},{"key":"5957_CR9","unstructured":"Fadhil, H., Aljawadi, M. & Ali, E. A. A. Neonatal respiratory distress in misan: causes. Risk Factors Outcomes  10(7), 123 (2019)."},{"issue":"1","key":"5957_CR10","first-page":"65","volume":"14","author":"SMK Abdelrahman","year":"2014","unstructured":"Abdelrahman, S. M. K., Hamed, S. M. A. & Nasr, A. Neonatal respiratory distress in Omdurman maternity hospital, Sudan. Sudan. J. Paediatr. 14 (1), 65 (2014).","journal-title":"Sudan. J. Paediatr."},{"issue":"1","key":"5957_CR11","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5334\/aogh.2739","volume":"86","author":"KAA Baseer","year":"2020","unstructured":"Baseer, K. A. A., Mohamed, M. & Abd-Elmawgood, E. A. Risk factors of respiratory diseases among neonates in neonatal intensive care unit of Qena university hospital, Egypt. Ann. Glob Heal. 86 (1), 22 (2020).","journal-title":"Ann. Glob Heal"},{"key":"5957_CR12","doi-asserted-by":"crossref","unstructured":"Aynalem, Y. A. et al. Incidence of respiratory distress and its predictors among neonates admitted to the neonatal intensive care unit, black Lion specialized hospital, addis ababa, Ethiopia. PLoS One 15(7), e0235544 (2020).","DOI":"10.1371\/journal.pone.0235544"},{"issue":"11","key":"5957_CR13","doi-asserted-by":"publisher","first-page":"e079063","DOI":"10.1136\/bmjopen-2023-079063","volume":"13","author":"WT Wondie","year":"2023","unstructured":"Wondie, W. T. et al. Incidence and predictors of respiratory distress syndrome among low birth weight neonates in the first seven days in Northwest Ethiopia comprehensive specialized hospitals, 2023: A retrospective follow-up study. BMJ Open. 13 (11), e079063 (2023).","journal-title":"BMJ Open."},{"issue":"1","key":"5957_CR14","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1179\/2046905513Y.0000000102","volume":"34","author":"T Duke","year":"2014","unstructured":"Duke, T. CPAP: a guide for clinicians in developing countries. Paediatr. Int. Child. Health. 34 (1), 3\u201311 (2014).","journal-title":"Paediatr. Int. Child. Health"},{"issue":"1","key":"5957_CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-017-1633-9","volume":"18","author":"NE Assefa","year":"2018","unstructured":"Assefa, N. E. et al. Risk factors of premature rupture of membranes in public hospitals at Mekele city, tigray, a case control study. BMC Pregnancy Childbirth. 18 (1), 1\u20137 (2018).","journal-title":"BMC Pregnancy Childbirth"},{"issue":"2","key":"5957_CR16","doi-asserted-by":"publisher","first-page":"257","DOI":"10.12816\/0043086","volume":"70","author":"SA Qari","year":"2018","unstructured":"Qari, S. A., Alsufyani, A. A., Muathin, S. H. & El Margoushy, N. M. Prevalence of respiratory distress syndrome in neonates. Egypt. J. Hosp. Med. 70 (2), 257\u2013264 (2018).","journal-title":"Egypt. J. Hosp. Med."},{"issue":"1","key":"5957_CR17","doi-asserted-by":"publisher","first-page":"76","DOI":"10.18203\/2349-3291.ijcp20160092","volume":"3","author":"V Sathenahalli","year":"2016","unstructured":"Sathenahalli, V., Dwivedi, D., Bajaj, N. & Singh, H. Predictors of poor outcome in neonates with respiratory distress. Int. J. Contemp. Pediatr. 3 (1), 76\u201379 (2016).","journal-title":"Int. J. Contemp. Pediatr."},{"issue":"July","key":"5957_CR18","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1007\/s12098-012-0914-6","volume":"80","author":"SN Singh","year":"2013","unstructured":"Singh, S. N. et al. Respiratory distress including meconium aspiration syndrome in vigorous neonates born through meconium stained amniotic fluid: incidence, onset, severity and predictors at birth. Indian J. Pediatr. 80 (July), 538\u2013543 (2013).","journal-title":"Indian J. Pediatr."},{"issue":"4","key":"5957_CR19","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.jnn.2021.10.014","volume":"28","author":"B Fenta","year":"2022","unstructured":"Fenta, B., Yetwale, A., Biyazin, T. & Dagnaw, Y. Respiratory distress and its associated factors among preterm neonates admitted to Mizan Tepi university teaching hospital, bench Maji zone, South West ethiopia, 2020. J. Neonatal Nurs. 28 (4), 249\u2013254 (2022).","journal-title":"J. Neonatal Nurs."},{"issue":"5","key":"5957_CR20","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/BF02731741","volume":"72","author":"N Delhi","year":"2005","unstructured":"Delhi, N., Kumar, A. & Bhatnagar, V. Respiratory distress in neonates. Indian J. Pediatr. 72 (5), 425\u2013428 (2005).","journal-title":"Indian J. Pediatr."},{"issue":"12","key":"5957_CR21","doi-asserted-by":"publisher","first-page":"e0278887","DOI":"10.1371\/journal.pone.0278887","volume":"17","author":"EF Enyew","year":"2022","unstructured":"Enyew, E. F., Bitew, D. A. & Gelagay, A. A. Incidence, time to recovery and predictors among neonates admitted with respiratory distress to the neonatal intensive care unit at the university of Gondar comprehensive specialized hospital, Northwest ethiopia, 2021. PLoS One. 17 (12), e0278887 (2022).","journal-title":"PLoS One"},{"issue":"11","key":"5957_CR22","first-page":"1267","volume":"30","author":"V Cond\u00f2","year":"2017","unstructured":"Cond\u00f2, V. et al. Neonatal respiratory distress syndrome: are risk factors the same in preterm and term infants? J. Matern Neonatal Med. Off J. Eur. Assoc. Perinat. Med. Fed. Asia Ocean. Perinat. Soc. Int. Soc. Perinat. Obstet. 30 (11), 1267\u20131272 (2017).","journal-title":"J. Matern Neonatal Med. Off J. Eur. Assoc. Perinat. Med. Fed. Asia Ocean. Perinat. Soc. Int. Soc. Perinat. Obstet."},{"issue":"3","key":"5957_CR23","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1007\/s00404-019-05208-7","volume":"300","author":"Y Li","year":"2019","unstructured":"Li, Y., Zhang, C. & Zhang, D. Cesarean section and the risk of neonatal respiratory distress syndrome: a meta-analysis. Arch. Gynecol. Obstet. 300 (3), 503\u2013517 (2019).","journal-title":"Arch. Gynecol. Obstet."},{"issue":"2","key":"5957_CR24","doi-asserted-by":"publisher","first-page":"187","DOI":"10.12701\/yujm.2018.35.2.187","volume":"35","author":"JH Kim","year":"2018","unstructured":"Kim, J. H., Lee, S. M. & Lee, Y. H. Risk factors for respiratory distress syndrome in full-term neonates. Yeungnam Univ. J. Med. 35 (2), 187\u2013191 (2018).","journal-title":"Yeungnam Univ. J. Med."},{"issue":"11","key":"5957_CR25","doi-asserted-by":"publisher","first-page":"e0207061","DOI":"10.1371\/journal.pone.0207061","volume":"13","author":"KH Ahn","year":"2018","unstructured":"Ahn, K. H. et al. Anterior placenta previa in the mid-trimester of pregnancy as a risk factor for neonatal respiratory distress syndrome. PLoS One. 13 (11), e0207061 (2018).","journal-title":"PLoS One"},{"key":"5957_CR26","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.preghy.2020.01.006","volume":"19","author":"T Tian","year":"2020","unstructured":"Tian, T., Wang, L., Ye, R., Liu, J. & Ren, A. Maternal hypertension, preeclampsia, and risk of neonatal respiratory disorders in a large-prospective cohort study. Pregnancy Hypertens [Internet]. 19, 131\u20137. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2210778920300076 (2020).","journal-title":"Pregnancy Hypertens [Internet]."},{"issue":"0","key":"5957_CR27","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1007\/s00592-019-01327-4","volume":"50","author":"Y Li","year":"2019","unstructured":"Li, Y., Wang, W. & Zhang, D. Maternal diabetes mellitus and risk of neonatal respiratory distress syndrome: a meta-analysis. Acta Diabetol [Internet] 50(0), 729\u201340. https:\/\/doi.org\/10.1007\/s00592-019-01327-4 (2019).","journal-title":"Acta Diabetol [Internet]"},{"key":"5957_CR28","unstructured":"West Gojjam zone health department. 2022\/23 Administrative Report. Finote Selam (2023)."},{"key":"5957_CR29","doi-asserted-by":"crossref","unstructured":"Kuti, B. P., Mohammed, L. O., Oladimeji, O. I., Ologun, B. G.,  Kuti, D. K. & Fawale, O. O.  Respiratory Distress in Nigerian Neonates: Prevalence, Severity, Risk, and Etiological Factors and Outcome. Nigerian Journal of Basic and Clinical Sciences 15 (1), 42\u201349 (2018).","DOI":"10.4103\/njbcs.njbcs_35_17"},{"key":"5957_CR30","unstructured":"Villar, J. & Bergsjo, P. WHO antenatal care randomized trial: manual for the implementation of the new model. In: WHO Antenatal care randomized trial: manual for the implementation of the new model. p. 37. (2002)."},{"key":"5957_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12884-018-2082-9","volume":"18","author":"DS Santana","year":"2018","unstructured":"Santana, D. S. et al. Perinatal outcomes in twin pregnancies complicated by maternal morbidity: evidence from the WHO multicountry survey on maternal and newborn health. BMC Pregnancy Childbirth. 18, 1\u201311 (2018).","journal-title":"BMC Pregnancy Childbirth"},{"key":"5957_CR32","unstructured":"Kliegman, R. M., Behrman, R. E., Jenson, H. B. & Stanton, B. M. D. Nelson Textbook of Pediatrics e-book (Elsevier Health Sciences, 2007)."},{"key":"5957_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1477-7827-8-2","volume":"8","author":"E Bresson","year":"2010","unstructured":"Bresson, E. et al. Gene expression profile of androgen modulated genes in the murine fetal developing lung. Reprod. Biol. Endocrinol. 8, 1\u201314 (2010).","journal-title":"Reprod. Biol. Endocrinol."},{"key":"5957_CR34","doi-asserted-by":"crossref","unstructured":"Yildiz Atar, H., Baatz, J. E. & Ryan, R. M. Molecular mechanisms of maternal diabetes effects on fetal and neonatal surfactant. Children 8(4), 281 (2021).","DOI":"10.3390\/children8040281"},{"issue":"3","key":"5957_CR35","doi-asserted-by":"publisher","first-page":"183","DOI":"10.5455\/medarh.2019.73.183-186","volume":"73","author":"TW Alfarwati","year":"2019","unstructured":"Alfarwati, T. W., Alamri, A. A., Alshahrani, M. A., Al-Wassia, H. & Al-, H. Incidence, risk factors and outcome of respiratory distress syndrome in term infants at academic centre, jeddah, Saudi Arabia. Med. Arch. 73 (3), 183 (2019).","journal-title":"Med. Arch."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-05957-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-05957-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-05957-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T07:27:13Z","timestamp":1757402833000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-05957-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,19]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5957"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-05957-3","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,19]]},"assertion":[{"value":"3 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Ethical clearance for the study was approved and obtained from the ethical review committee of the Department of Public Health, College of Health Sciences, and Debre Markos University with confirmation number: HSC\/RCS\/147\/11\/15. A formal letter of cooperation from the University was submitted to the administrative bodies of both hospitals for data extraction. Permission was obtained from all relevant authorities in the hospitals. The data extractors managed the search and retrieval of the selected samples\u2019 medical records. Since the data were extracted from secondary source the need to obtain informed consent was waived by Debre Markos University college of Medicine and Health Sciences review board. Confidentiality was maintained by not including the names and identifications of study participants on the extraction tool. All extracted information was coded and stored in a secure room before being entered into the computer, which was then password-protected. Parental consent was not obtained as the study used secondary data.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical consideration"}},{"value":"The need to obtain informed consent was waived by Debre Markos University College of Medicine and Health Sciences institutional review board.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent statement"}}],"article-number":"30444"}}