{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T04:18:57Z","timestamp":1751429937812,"version":"3.41.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-06428-5","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T17:53:13Z","timestamp":1751392393000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Practice patterns of vascular neurologists in timing anticoagulation for high risk stroke mechanisms versus atrial fibrillation"],"prefix":"10.1038","volume":"15","author":[{"given":"Farhan","family":"Khan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivien","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shadi","family":"Yaghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam","family":"Prabhakaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,1]]},"reference":[{"key":"6428_CR1","unstructured":"Optimal timing of anticoagulation. after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial - The Lancet [Internet]. [date unknown];[cited 2025 Jan 17 ] Available from: https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(24)02197-4\/fulltext"},{"issue":"26","key":"6428_CR2","doi-asserted-by":"publisher","first-page":"2411","DOI":"10.1056\/NEJMoa2303048","volume":"388","author":"U Fischer","year":"2023","unstructured":"Fischer, U. et al. Early versus later anticoagulation for stroke with atrial fibrillation. N Engl. J. Med. 388 (26), 2411\u20132421 (2023).","journal-title":"N Engl. J. Med."},{"issue":"14","key":"6428_CR3","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1161\/CIRCULATIONAHA.122.060666","volume":"146","author":"J Oldgren","year":"2022","unstructured":"Oldgren, J. et al. Early versus delayed Non\u2013Vitamin K antagonist oral anticoagulant therapy after acute ischemic stroke in atrial fibrillation (TIMING): A Registry-Based randomized controlled noninferiority study. Circulation 146 (14), 1056\u20131066 (2022).","journal-title":"Circulation"},{"issue":"8","key":"6428_CR4","doi-asserted-by":"publisher","first-page":"2093","DOI":"10.1161\/STROKEAHA.118.022856","volume":"50","author":"R Altavilla","year":"2019","unstructured":"Altavilla, R. et al. Anticoagulation after stroke in patients with atrial fibrillation. Stroke 50 (8), 2093\u20132100 (2019).","journal-title":"Stroke"},{"issue":"1","key":"6428_CR5","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1161\/CIR.0000000000001193","volume":"149","author":"JA Joglar","year":"2024","unstructured":"Joglar, J. A. et al. 2023 ACC\/AHA\/ACCP\/HRS guideline for the diagnosis and management of atrial fibrillation: A report of the American college of cardiology\/american heart association joint committee on clinical practice guidelines. Circulation 149 (1), e1\u2013e156 (2024).","journal-title":"Circulation"},{"issue":"5","key":"6428_CR6","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1161\/STROKEAHA.121.036695","volume":"53","author":"S Kimura","year":"2022","unstructured":"Kimura, S. et al. Practical 1-2-3-4-Day rule for starting direct oral anticoagulants after ischemic stroke with atrial fibrillation: combined Hospital-Based cohort study. Stroke 53 (5), 1540\u20131549 (2022).","journal-title":"Stroke"},{"issue":"1","key":"6428_CR7","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S1474-4422(18)30356-9","volume":"18","author":"DJ Seiffge","year":"2019","unstructured":"Seiffge, D. J. et al. Timing of anticoagulation after recent ischaemic stroke in patients with atrial fibrillation. Lancet Neurol. 18 (1), 117\u2013126 (2019).","journal-title":"Lancet Neurol."},{"issue":"11","key":"6428_CR8","doi-asserted-by":"publisher","first-page":"2742","DOI":"10.1161\/STROKEAHA.116.013827","volume":"47","author":"X Bu","year":"2016","unstructured":"Bu, X. et al. Antiphosphatidylserine antibodies and clinical outcomes in patients with acute ischemic stroke. Stroke 47 (11), 2742\u20132748 (2016).","journal-title":"Stroke"},{"issue":"15","key":"6428_CR9","doi-asserted-by":"publisher","first-page":"e205","DOI":"10.1161\/CIR.0000000000001092","volume":"146","author":"GN Levine","year":"2022","unstructured":"Levine, G. N. et al. Management of patients at risk for and with left ventricular thrombus: A scientific statement from the American heart association. Circulation 146 (15), e205\u2013e223 (2022).","journal-title":"Circulation"},{"key":"6428_CR10","first-page":"47","volume":"124","author":"A Onalan","year":"2024","unstructured":"Onalan, A. et al. Safety and effectiveness of anticoagulation in the management of acute stroke and transient ischemic attack due to intracranial and extracranial non-occlusive thrombus. J. Clin. Neurosci. Off J. Neurosurg. Soc. Australas. 124, 47\u201353 (2024).","journal-title":"J. Clin. Neurosci. Off J. Neurosurg. Soc. Australas"},{"issue":"13","key":"6428_CR11","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1056\/NEJMoa0804656","volume":"359","author":"W Hacke","year":"2008","unstructured":"Hacke, W. et al. Thrombolysis with Alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl. J. Med. 359 (13), 1317\u20131329 (2008).","journal-title":"N Engl. J. Med."},{"issue":"8","key":"6428_CR12","doi-asserted-by":"publisher","first-page":"e029070","DOI":"10.1161\/JAHA.122.029070","volume":"12","author":"X Zhou","year":"2023","unstructured":"Zhou, X. et al. Clinical outcome after left ventricular Thrombus resolution: who needs Long-Term or lifetime use of anticoagulants?? J. Am. Heart Assoc. 12 (8), e029070 (2023).","journal-title":"J. Am. Heart Assoc."},{"issue":"2","key":"6428_CR13","doi-asserted-by":"publisher","first-page":"e002688","DOI":"10.1136\/openhrt-2024-002688","volume":"11","author":"MC Olma","year":"2024","unstructured":"Olma, M. C. et al. Timing of oral anticoagulation in atrial fibrillation patients after acute ischaemic stroke and outcome after 3 months: results of the multicentre Berlin atrial fibrillation registry. Open. Heart. 11 (2), e002688 (2024).","journal-title":"Open. Heart"},{"key":"6428_CR14","unstructured":"Primary Stroke Center Concept. Strengths and Limitations - PMC [Internet]. [date unknown];[cited 2024 Sep 11 ] Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3399134\/"},{"key":"6428_CR15","doi-asserted-by":"publisher","unstructured":"Bridging May Increase the Risk of Symptomatic Intracranial Hemorrhage in Thrombectomy Patients With Low Alberta. Stroke Program Early Computed Tomography Score | Stroke [Internet]. [date unknown];[cited 2024 Sep 17 ] Available from: https:\/\/www.ahajournals.org\/doi\/full\/https:\/\/doi.org\/10.1161\/STROKEAHA.120.030508","DOI":"10.1161\/STROKEAHA.120.030508"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-06428-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-06428-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-06428-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T17:53:14Z","timestamp":1751392394000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-06428-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["6428"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-06428-5","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,1]]},"assertion":[{"value":"17 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"21467"}}