{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:44:07Z","timestamp":1788669847886,"version":"build-2803163510"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-07617-y","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T21:12:22Z","timestamp":1751404342000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Physico-mechanical characterization of 3D-printed PLGA for patient-specific resorbable implants in craniofacial surgery"],"prefix":"10.1038","volume":"15","author":[{"given":"Dimitri","family":"Kulker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Pepin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Laure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Venin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Biglione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Pare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,1]]},"reference":[{"key":"7617_CR1","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1177\/27325016231221424","volume":"5","author":"W Ahmad","year":"2024","unstructured":"Ahmad, W. et al. Fixation in maxillofacial Surgery\u2014Past, present and future: A narrative review Article. FACE 5, 126\u2013132. https:\/\/doi.org\/10.1177\/27325016231221424 (2024).","journal-title":"FACE"},{"key":"7617_CR2","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1089\/fpsam.2020.0129","volume":"22","author":"C Batut","year":"2020","unstructured":"Batut, C., Par\u00e9, A., Kulker, D., Listrat, A. & Laure, B. How accurate is Computer-Assisted orbital hypertelorism surgery?? Comparison of the Three-Dimensional surgical planning with the postoperative outcomes. Facial Plast. Surg. Aesthet. Med. 22, 433\u2013440. https:\/\/doi.org\/10.1089\/fpsam.2020.0129 (2020).","journal-title":"Facial Plast. Surg. Aesthet. Med."},{"key":"7617_CR3","doi-asserted-by":"publisher","unstructured":"Schlund, M., Par\u00e9, A., Joly, A. & Laure, B. Computer-assisted surgery in facial bipartition surgery. J. Maxillofac. Oral Surg. 76 https:\/\/doi.org\/10.1016\/j.joms.2017.12.013 (2018).","DOI":"10.1016\/j.joms.2017.12.013"},{"key":"7617_CR4","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.wneu.2022.02.031","volume":"161","author":"G Calluaud","year":"2022","unstructured":"Calluaud, G., Pare, A., Kulker, D., Listrat, A. & Laure, B. Computer-Assisted frontofacial monobloc advancement and facial bipartition for Pfeiffer syndrome: surgical technique. World Neurosurg. 161, 97\u2013102. https:\/\/doi.org\/10.1016\/j.wneu.2022.02.031 (2022).","journal-title":"World Neurosurg."},{"key":"7617_CR5","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/S0194-5998(99)70183-X","volume":"121","author":"WE Berryhill","year":"1999","unstructured":"Berryhill, W. E., Rimell, F. L., Ness, J., Marentette, L. & Haines, S. J. Fate of rigid fixation in pediatric craniofacial surgery. Otolaryngol. --head Neck Surg. 121, 269\u2013273. https:\/\/doi.org\/10.1016\/S0194-5998(99)70183-X (1999).","journal-title":"Otolaryngol. --head Neck Surg."},{"key":"7617_CR6","doi-asserted-by":"publisher","first-page":"471","DOI":"10.3390\/children9040471","volume":"9","author":"P Heye","year":"2022","unstructured":"Heye, P. et al. Making hardware removal unnecessary by using resorbable implants for osteosynthesis in children. Children 9, 471. https:\/\/doi.org\/10.3390\/children9040471 (2022).","journal-title":"Children"},{"key":"7617_CR7","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1097\/SCS.0000000000003166","volume":"28","author":"LG Branch","year":"2017","unstructured":"Branch, L. G. et al. Long-Term outcomes of pediatric cranial reconstruction using resorbable plating systems for the treatment of craniosynostosis. J. Craniofac. Surg. 28, 26\u201329. https:\/\/doi.org\/10.1097\/SCS.0000000000003166 (2017).","journal-title":"J. Craniofac. Surg."},{"key":"7617_CR8","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/j.pharma.2021.11.009","volume":"80","author":"YR Chavan","year":"2022","unstructured":"Chavan, Y. R., Tambe, S. M., Jain, D. D., Khairnar, S. V. & Amin, P. D. Redefining the importance of polylactide-co-glycolide acid (PLGA) in drug delivery. Ann. Pharm. Fr. 80, 603\u2013616. https:\/\/doi.org\/10.1016\/j.pharma.2021.11.009 (2022).","journal-title":"Ann. Pharm. Fr."},{"key":"7617_CR9","doi-asserted-by":"publisher","first-page":"19516","DOI":"10.1038\/s41598-024-69888-1","volume":"14","author":"F Madani","year":"2024","unstructured":"Madani, F. et al. Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood\u2013brain\u2013barrier in a glioblastoma model. Sci. Rep. 14, 19516. https:\/\/doi.org\/10.1038\/s41598-024-69888-1 (2024).","journal-title":"Sci. Rep."},{"key":"7617_CR10","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1098\/rsfs.2011.0123","volume":"2","author":"Z Pan","year":"2012","unstructured":"Pan, Z. & Ding, J. Poly(lactide- Co -glycolide) porous scaffolds for tissue engineering and regenerative medicine. Interface Focus. 2, 366\u2013377. https:\/\/doi.org\/10.1098\/rsfs.2011.0123 (2012).","journal-title":"Interface Focus"},{"key":"7617_CR11","doi-asserted-by":"publisher","unstructured":"Sun, F. et al. Application of 3D-printed, PLGA-based Scaffolds in bone tissue engineering. IJMS. https:\/\/doi.org\/10.3390\/ijms23105831 (2022).","DOI":"10.3390\/ijms23105831"},{"key":"7617_CR12","doi-asserted-by":"publisher","first-page":"e2401589","DOI":"10.1002\/advs.202401589","volume":"11","author":"M Zhang","year":"2024","unstructured":"Zhang, M. et al. Personalized PLGA\/BCL scaffold with hierarchical porous structure resembling Periosteum-Bone complex enables efficient repair of bone defect. Adv. Sci. (Weinh). 11, e2401589. https:\/\/doi.org\/10.1002\/advs.202401589 (2024).","journal-title":"Adv. Sci. (Weinh)"},{"key":"7617_CR13","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.bioactmat.2020.08.016","volume":"6","author":"D Zhao","year":"2021","unstructured":"Zhao, D. et al. Poly(lactic-co-glycolic acid)-based composite bone-substitute materials. Bioactive Mater. 6, 346\u2013360. https:\/\/doi.org\/10.1016\/j.bioactmat.2020.08.016 (2021).","journal-title":"Bioactive Mater."},{"key":"7617_CR14","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.bjoms.2006.12.008","volume":"45","author":"E Pilling","year":"2007","unstructured":"Pilling, E. et al. An experimental study of the Biomechanical stability of ultrasound-activated pinned (SonicWeld Rx\u00ae+Resorb-X\u00ae) and screwed fixed (Resorb-X\u00ae) resorbable materials for osteosynthesis in the treatment of simulated craniosynostosis in sheep. Br. J. Oral Maxillofac. Surg. 45, 451\u2013456. https:\/\/doi.org\/10.1016\/j.bjoms.2006.12.008 (2007).","journal-title":"Br. J. Oral Maxillofac. Surg."},{"key":"7617_CR15","doi-asserted-by":"publisher","first-page":"18143","DOI":"10.1038\/s41598-020-75299-9","volume":"10","author":"B Gareb","year":"2020","unstructured":"Gareb, B. et al. Comparison of the mechanical properties of biodegradable and titanium osteosynthesis systems used in oral and maxillofacial surgery. Sci. Rep. 10, 18143. https:\/\/doi.org\/10.1038\/s41598-020-75299-9 (2020).","journal-title":"Sci. Rep."},{"key":"7617_CR16","doi-asserted-by":"publisher","first-page":"756","DOI":"10.18063\/ijb.756","volume":"9","author":"A Valls-Esteve","year":"2023","unstructured":"Valls-Esteve, A. et al. A state-of-the-art guide about the effects of sterilization processes on 3D-printed materials for surgical planning and medical applications: A comparative study. IJB 9, 756. https:\/\/doi.org\/10.18063\/ijb.756 (2023).","journal-title":"IJB"},{"key":"7617_CR17","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s41205-024-00207-0","volume":"10","author":"M Maintz","year":"2024","unstructured":"Maintz, M. et al. Patient-specific implants made of 3D printed bioresorbable polymers at the point-of-care: material, technology, and scope of surgical application. 3D Print. Med. 10, 13. https:\/\/doi.org\/10.1186\/s41205-024-00207-0 (2024).","journal-title":"3D Print. Med."},{"key":"7617_CR18","doi-asserted-by":"publisher","first-page":"572","DOI":"10.3390\/polym13040572","volume":"13","author":"M Gradwohl","year":"2021","unstructured":"Gradwohl, M. et al. Effects of two melt extrusion based additive manufacturing technologies and common sterilization methods on the properties of a medical grade PLGA copolymer. Polymers 13, 572. https:\/\/doi.org\/10.3390\/polym13040572 (2021).","journal-title":"Polymers"},{"key":"7617_CR19","doi-asserted-by":"publisher","first-page":"5762","DOI":"10.1016\/j.surfcoat.2008.06.114","volume":"202","author":"MH Lee","year":"2008","unstructured":"Lee, M. H. et al. Effects of low temperature hydrogen peroxide gas on sterilization and cytocompatibility of porous poly(d,l-lactic-co-glycolic acid) scaffolds. Surf. Coat. Technol. 202, 5762\u20135767. https:\/\/doi.org\/10.1016\/j.surfcoat.2008.06.114 (2008).","journal-title":"Surf. Coat. Technol."},{"key":"7617_CR20","doi-asserted-by":"publisher","unstructured":"Del Monaco, A., Duek, E., Andrade, A. J. P. D. & Malmonge, S. Alternative methods of sterilization on films of polymers: Poly(-L-lactic acid) (PLLA), Poly(L-lactic acid-co-glycolic acid) (PLGA) and Poly(-LD-lactic acid) (PLDLA), for bioresorbable vascular scaffolds models. TASJ 248\u2013256. https:\/\/doi.org\/10.32640\/tasj.2018.4.248 (2018).","DOI":"10.32640\/tasj.2018.4.248"},{"key":"7617_CR21","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1097\/SCS.0000000000009014","volume":"34","author":"D Kulker","year":"2023","unstructured":"Kulker, D. et al. Surgical management of hypertelorism: the 3D animated technical note. J. Craniofac. Surg. 34, 391\u2013392. https:\/\/doi.org\/10.1097\/SCS.0000000000009014 (2023).","journal-title":"J. Craniofac. Surg."},{"key":"7617_CR22","doi-asserted-by":"publisher","first-page":"2706","DOI":"10.1021\/acsapm.0c00315","volume":"2","author":"MA Murcia Valderrama","year":"2020","unstructured":"Murcia Valderrama, M. A., Van Putten, R. J. & Gruter, G. J. M. PLGA barrier materials from CO 2. The influence of lactide Co-monomer on glycolic acid polyesters. ACS Appl. Polym. Mater. 2, 2706\u20132718. https:\/\/doi.org\/10.1021\/acsapm.0c00315 (2020).","journal-title":"ACS Appl. Polym. Mater."},{"key":"7617_CR23","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1039\/b922045c","volume":"135","author":"ZM Zhang","year":"2010","unstructured":"Zhang, Z. M., Chen, S. & Liang, Y. Z. Baseline correction using adaptive iteratively reweighted penalized least squares. Analyst 135, 1138. https:\/\/doi.org\/10.1039\/b922045c (2010).","journal-title":"Analyst"},{"key":"7617_CR24","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.1016\/j.polymdegradstab.2011.07.011","volume":"96","author":"E Vey","year":"2011","unstructured":"Vey, E. et al. Degradation kinetics of poly(lactic-co-glycolic) acid block copolymer cast films in phosphate buffer solution as revealed by infrared and Raman spectroscopies. Polym. Degrad. Stab. 96, 1882\u20131889. https:\/\/doi.org\/10.1016\/j.polymdegradstab.2011.07.011 (2011).","journal-title":"Polym. Degrad. Stab."},{"key":"7617_CR25","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.3390\/polym16131765","volume":"16","author":"Z Chen","year":"2024","unstructured":"Chen, Z. et al. Degradation behaviors of polylactic acid, polyglycolic acid, and their copolymer films in simulated marine environments. Polymers 16, 1765. https:\/\/doi.org\/10.3390\/polym16131765 (2024).","journal-title":"Polymers"},{"key":"7617_CR26","doi-asserted-by":"publisher","first-page":"e53095","DOI":"10.1002\/app.53095","volume":"139","author":"A Zennaki","year":"2022","unstructured":"Zennaki, A. et al. Effect of annealing on thermal and dynamic mechanical properties of poly(lactic acid). J. Appl. Polym. Sci. 139, e53095. https:\/\/doi.org\/10.1002\/app.53095 (2022).","journal-title":"J. Appl. Polym. Sci."},{"key":"7617_CR27","doi-asserted-by":"publisher","unstructured":"Melo, L. P. D., Salmoria, G. V., Fancello, E. A. & Roesler, C. R. D. M. Effect of injection molding melt temperatures on PLGA craniofacial plate properties during in vitro degradation. Int. J. Biomater. 1\u201311. https:\/\/doi.org\/10.1155\/2017\/1256537 (2017).","DOI":"10.1155\/2017\/1256537"},{"key":"7617_CR28","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1080\/00914037.2014.886247","volume":"64","author":"I Carmagnola","year":"2015","unstructured":"Carmagnola, I. et al. Poly(Lactic Acid)-Based blends with tailored physicochemical properties for tissue engineering applications: A case study. Int. J. Polym. Mater. 64, 90\u201398. https:\/\/doi.org\/10.1080\/00914037.2014.886247 (2015).","journal-title":"Int. J. Polym. Mater."},{"key":"7617_CR29","doi-asserted-by":"publisher","DOI":"10.1007\/s40964-024-00608-x","author":"MS Cadete","year":"2024","unstructured":"Cadete, M. S., Gomes, T. E. P., Gon\u00e7alves, I. & Neto, V. Influence of 3D-printing deposition parameters on crystallinity and morphing properties of PLA-based materials. Prog Addit. Manuf. https:\/\/doi.org\/10.1007\/s40964-024-00608-x (2024).","journal-title":"Prog Addit. Manuf."},{"key":"7617_CR30","doi-asserted-by":"publisher","first-page":"9664","DOI":"10.1021\/ma071737c","volume":"40","author":"P Pan","year":"2007","unstructured":"Pan, P., Zhu, B. & Inoue, Y. Enthalpy relaxation and embrittlement of Poly(l -lactide) during Physical Aging. Macromolecules 40, 9664\u20139671. https:\/\/doi.org\/10.1021\/ma071737c (2007).","journal-title":"Macromolecules"},{"key":"7617_CR31","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.tca.2005.02.014","volume":"433","author":"R Surana","year":"2005","unstructured":"Surana, R., Pyne, A., Rani, M. & Suryanarayanan, R. Measurement of enthalpic relaxation by differential scanning calorimetry\u2014effect of experimental conditions. Thermochim Acta. 433, 173\u2013182. https:\/\/doi.org\/10.1016\/j.tca.2005.02.014 (2005).","journal-title":"Thermochim Acta"},{"key":"7617_CR32","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.3390\/polym13132115","volume":"13","author":"S P\u00e9rez Davila","year":"2021","unstructured":"P\u00e9rez Davila, S., Gonz\u00e1lez Rodr\u00edguez, L., Chiussi, S., Serra, J. & Gonz\u00e1lez, P. How to sterilize polylactic acid based medical devices?? Polymers 13, 2115. https:\/\/doi.org\/10.3390\/polym13132115 (2021).","journal-title":"Polymers"},{"key":"7617_CR33","doi-asserted-by":"publisher","first-page":"3377","DOI":"10.1016\/j.polymer.2013.04.027","volume":"54","author":"Z Wei","year":"2013","unstructured":"Wei, Z. et al. Insight into the annealing peak and microstructural changes of poly(l-lactic acid) by annealing at elevated temperatures. Polymer 54, 3377\u20133384. https:\/\/doi.org\/10.1016\/j.polymer.2013.04.027 (2013).","journal-title":"Polymer"},{"key":"7617_CR34","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.vibspec.2014.01.012","volume":"71","author":"H Keles","year":"2014","unstructured":"Keles, H., Naylor, A., Clegg, F. & Sammon, C. Studying the release of hGH from gamma-irradiated PLGA microparticles using ATR-FTIR imaging. Vib. Spectrosc. 71, 76\u201384. https:\/\/doi.org\/10.1016\/j.vibspec.2014.01.012 (2014).","journal-title":"Vib. Spectrosc."},{"key":"7617_CR35","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1016\/S0584-8539(97)00039-1","volume":"53","author":"G Kister","year":"1997","unstructured":"Kister, G., Cassanas, G. & Vert, M. Morphology of poly(glycolic acid) by IR and Raman spectroscopies. Spectrochim Acta Mol. Biomol. Spectrosc. 53, 1399\u20131403. https:\/\/doi.org\/10.1016\/S0584-8539(97)00039-1 (1997).","journal-title":"Spectrochim Acta Mol. Biomol. Spectrosc."},{"key":"7617_CR36","doi-asserted-by":"publisher","unstructured":"Biomaterials et al. Degradable polymeric materials for osteosynthesis: Tutorial. eCM 16, 80\u201391 (2008). https:\/\/doi.org\/10.22203\/eCM.v016a09","DOI":"10.22203\/eCM.v016a09"},{"key":"7617_CR37","unstructured":"Sosnowski, E. P. & Morrison, J. Sterilization of medical 3D printed plastics: Is H2O2 vapour suitable? In CMBES Proceedings. Vol.  40 (2017)."},{"key":"7617_CR38","doi-asserted-by":"publisher","unstructured":"Butt, J. & Bhaskar, R. Investigating the effects of annealing on the mechanical properties of FFF-printed thermoplastics. JMMP 4 (38). https:\/\/doi.org\/10.3390\/jmmp4020038 (2020).","DOI":"10.3390\/jmmp4020038"},{"key":"7617_CR39","doi-asserted-by":"publisher","first-page":"111687","DOI":"10.1016\/j.matdes.2023.111687","volume":"226","author":"W Yu","year":"2023","unstructured":"Yu, W., Wang, X., Yin, X., Ferraris, E. & Zhang, J. The effects of thermal annealing on the performance of material extrusion 3D printed polymer parts. Mater. Design. 226, 111687. https:\/\/doi.org\/10.1016\/j.matdes.2023.111687 (2023).","journal-title":"Mater. Design"},{"key":"7617_CR40","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1007\/s11043-020-09451-3","volume":"25","author":"PB de Castro","year":"2021","unstructured":"de Castro, P. B., Salmoria, G. V., Roesler, C. R. D. M., Rosa, D., Fancello, E. A. A study on the response of PLGA 85\/15 under compression and heat-treatment testing cycles. Mech. Time-Depend Mater. 25, 411\u2013427. https:\/\/doi.org\/10.1007\/s11043-020-09451-3 (2021).","journal-title":"Mech. Time-Depend Mater."},{"key":"7617_CR41","doi-asserted-by":"publisher","first-page":"105932","DOI":"10.1016\/j.engfailanal.2021.105932","volume":"132","author":"A Szust","year":"2022","unstructured":"Szust, A. & Adamski, G. Using thermal annealing and salt remelting to increase tensile properties of 3D FDM prints. Eng. Fail. Anal. 132, 105932. https:\/\/doi.org\/10.1016\/j.engfailanal.2021.105932 (2022).","journal-title":"Eng. Fail. Anal."},{"key":"7617_CR42","doi-asserted-by":"crossref","unstructured":"Kikinis, R., Pieper, S. D. & Vosburgh, K. G. 3D Slicer: A Platform for Subject-Specific Image Analysis, Visualization, and Clinical Support. In: Jolesz, F. A. (ed.) Intraoperative Imaging and Image-Guided Therapy, 277\u2013289, Springer New York. https:\/\/doi.org\/10.1007\/978-1-4614-7657-3_19 (2014).","DOI":"10.1007\/978-1-4614-7657-3_19"},{"key":"7617_CR43","doi-asserted-by":"publisher","first-page":"rbae066","DOI":"10.1093\/rb\/rbae066","volume":"11","author":"X Wang","year":"2024","unstructured":"Wang, X. et al. 3D printing materials and 3D printed surgical devices in oral and maxillofacial surgery: design, workflow and effectiveness. Regenerative Biomaterials. 11, rbae066. https:\/\/doi.org\/10.1093\/rb\/rbae066 (2024).","journal-title":"Regenerative Biomaterials"},{"key":"7617_CR44","doi-asserted-by":"publisher","unstructured":"Oth, O., Dauchot, C., Orellana, M. & Glineur, R. How to sterilize 3D printed objects for surgical use? An evaluation of the volumetric deformation of 3D-printed genioplasty guide in PLA and PETG after sterilization by low-temperature hydrogen peroxide gas plasma. TODENTJ 13, 410\u2013417. https:\/\/doi.org\/10.2174\/1874210601913010410 (2019).","DOI":"10.2174\/1874210601913010410"},{"key":"7617_CR45","doi-asserted-by":"publisher","first-page":"3539","DOI":"10.3390\/ijms23073539","volume":"23","author":"P Rynio","year":"2022","unstructured":"Rynio, P. et al. Effects of sterilization methods on different 3D printable materials for templates of Physician-Modified aortic stent grafts used in vascular Surgery\u2014A preliminary study. IJMS 23, 3539. https:\/\/doi.org\/10.3390\/ijms23073539 (2022).","journal-title":"IJMS"},{"key":"7617_CR46","doi-asserted-by":"publisher","first-page":"2827","DOI":"10.1016\/j.biomaterials.2004.08.031","volume":"26","author":"CJ Loo","year":"2005","unstructured":"Loo, C. J., Ooi, S.,  Elyna Wee, C. P. H. &  Chiang Freddy Boey, Y. Effect of isothermal annealing on the hydrolytic degradation rate of poly(lactide-co-glycolide) (PLGA). Biomaterials 26, 2827\u20132833. https:\/\/doi.org\/10.1016\/j.biomaterials.2004.08.031 (2005).","journal-title":"Biomaterials"},{"key":"7617_CR47","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/BF02040443","volume":"10","author":"U Bianchi","year":"1971","unstructured":"Bianchi, U. Pressure dependence of glass transition temperature in polymers. Rheol Acta. 10, 213\u2013213. https:\/\/doi.org\/10.1007\/BF02040443 (1971).","journal-title":"Rheol Acta"},{"key":"7617_CR48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-3-662-53605-6_270-2","volume-title":"Encyclopedia of Continuum Mechanics","author":"A Aulova","year":"2019","unstructured":"Aulova, A., Oseli, A., Bek, M., Prodan, T. & Emri, I. Effect of pressure on mechanical properties of polymers. in Encyclopedia of Continuum Mechanics (eds Altenbach, H. & \u00d6chsner, A.) 1\u201314 https:\/\/doi.org\/10.1007\/978-3-662-53605-6_270-2 (Springer, 2019)."},{"key":"7617_CR49","doi-asserted-by":"publisher","first-page":"5977","DOI":"10.2147\/IJN.S202457","volume":"14","author":"Y Zhu","year":"2019","unstructured":"Zhu, Y. et al. 3D printed zirconia ceramic hip joint with precise structure and broad-spectrum antibacterial properties. IJN 14, 5977\u20135987. https:\/\/doi.org\/10.2147\/IJN.S202457 (2019).","journal-title":"IJN"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-07617-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-07617-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-07617-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T21:12:24Z","timestamp":1751404344000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-07617-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["7617"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-07617-y","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,1]]},"assertion":[{"value":"25 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"22225"}}