{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:56:19Z","timestamp":1789062979935,"version":"build-2803163510"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Tai\u2019an Innovation Development Program for Science and Technology","award":["2021NS141"],"award-info":[{"award-number":["2021NS141"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-09115-7","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T15:01:04Z","timestamp":1751468464000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Multimodal nomogram integrating deep learning radiomics and hemodynamic parameters for early prediction of post-craniotomy intracranial hypertension"],"prefix":"10.1038","volume":"15","author":[{"given":"Zunfeng","family":"Fu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongqiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanlin","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weifu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunju","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,2]]},"reference":[{"key":"9115_CR1","doi-asserted-by":"crossref","unstructured":"Raboel, P. H. et al. M,. Intracranial pressure monitoring: invasive versus non-invasive methods: a review. Crit. Care Res. Pract. 2012, 950393. (2012).","DOI":"10.1155\/2012\/950393"},{"issue":"8","key":"9115_CR2","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1080\/02699052.2019.1605621","volume":"33","author":"AR Stevens","year":"2019","unstructured":"Stevens, A. R. et al. Optical pupillometry in traumatic brain injury: neurological pupil index and its relationship with intracranial pressure through significant event analysis. Brain Inj. 33 (8), 1032\u20131038 (2019).","journal-title":"Brain Inj"},{"issue":"6","key":"9115_CR3","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1055\/s-0043-1764411","volume":"81","author":"BCD Faria","year":"2023","unstructured":"Faria, B. C. D. et al. The use of noninvasive measurements of intracranial pressure in patients with traumatic brain injury: a narrative review. Arq. Neuropsiquiatr. 81 (6), 551\u2013563 (2023).","journal-title":"Arq. Neuropsiquiatr."},{"key":"9115_CR4","doi-asserted-by":"crossref","unstructured":"Harary, M., Dolmans, R. G. F. & Gormley, W. B. Intracranial pressure Monitoring-Review and avenues for development. Sens. (Basel), 18(2). (2018).","DOI":"10.3390\/s18020465"},{"issue":"1","key":"9115_CR5","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s13054-022-03978-2","volume":"26","author":"FA Rasulo","year":"2022","unstructured":"Rasulo, F. A. et al. Transcranial doppler as a screening test to exclude intracranial hypertension in brain-injured patients: the IMPRESSIT-2 prospective multicenter international study. Crit. Care. 26 (1), 110 (2022).","journal-title":"Crit. Care"},{"issue":"6","key":"9115_CR6","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1590\/0004-282x-anp-2022-e006","volume":"80","author":"C Robba","year":"2022","unstructured":"Robba, C. Measuring optic nerve sheath diameter using ultrasonography for the detection of Non invasive intracranial pressure: what it is and what it is not. Arq. Neuropsiquiatr. 80 (6), 547\u2013549 (2022).","journal-title":"Arq. Neuropsiquiatr."},{"issue":"1","key":"9115_CR7","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1186\/s13054-020-03105-z","volume":"24","author":"C Robba","year":"2020","unstructured":"Robba, C. et al. Multimodal non-invasive assessment of intracranial hypertension: an observational study. Crit. Care. 24 (1), 379 (2020).","journal-title":"Crit. Care"},{"issue":"Suppl 1","key":"9115_CR8","first-page":"S32","volume":"24","author":"F Brain Trauma","year":"2007","unstructured":"Brain Trauma, F. et al. Guidelines for the management of severe traumatic brain injury. V. Deep vein thrombosis prophylaxis. J. Neurotrauma. 24 (Suppl 1), S32\u2013S36 (2007).","journal-title":"J. Neurotrauma"},{"issue":"4","key":"9115_CR9","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/s00701-017-3119-y","volume":"159","author":"AK Demetriades","year":"2017","unstructured":"Demetriades, A. K. Intracranial pressure monitoring after primary decompressive craniectomy: is it useful? Acta Neurochir. (Wien). 159 (4), 623\u2013624 (2017).","journal-title":"Acta Neurochir. (Wien)"},{"issue":"4","key":"9115_CR10","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1007\/s00701-017-3118-z","volume":"159","author":"E Picetti","year":"2017","unstructured":"Picetti, E. et al. Intracranial pressure monitoring after primary decompressive craniectomy in traumatic brain injury: a clinical study. Acta Neurochir. (Wien). 159 (4), 615\u2013622 (2017).","journal-title":"Acta Neurochir. (Wien)"},{"issue":"26","key":"9115_CR11","doi-asserted-by":"publisher","first-page":"2471","DOI":"10.1056\/NEJMoa1207363","volume":"367","author":"RM Chesnut","year":"2012","unstructured":"Chesnut, R. M. et al. A trial of intracranial-pressure monitoring in traumatic brain injury. N Engl. J. Med. 367 (26), 2471\u20132481 (2012).","journal-title":"N Engl. J. Med."},{"issue":"1","key":"9115_CR12","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1186\/cc13713","volume":"18","author":"S Melhem","year":"2014","unstructured":"Melhem, S., Shutter, L. & Kaynar, A. A trial of intracranial pressure monitoring in traumatic brain injury. Crit. Care. 18 (1), 302 (2014).","journal-title":"Crit. Care"},{"key":"9115_CR13","doi-asserted-by":"publisher","first-page":"1472494","DOI":"10.3389\/fneur.2024.1472494","volume":"15","author":"Z Fu","year":"2024","unstructured":"Fu, Z. et al. Post-craniotomy intracranial pressure monitoring: a novel approach combining optic nerve sheath diameter ultrasonography and cervical-cerebral arterial ultrasound. Front. Neurol. 15, 1472494 (2024).","journal-title":"Front. Neurol."},{"issue":"12","key":"9115_CR14","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1038\/nrclinonc.2017.141","volume":"14","author":"P Lambin","year":"2017","unstructured":"Lambin, P. et al. Radiomics: the Bridge between medical imaging and personalized medicine. Nat. Rev. Clin. Oncol. 14 (12), 749\u2013762 (2017).","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"15","key":"9115_CR15","doi-asserted-by":"publisher","first-page":"3583","DOI":"10.1158\/1078-0432.CCR-17-2507","volume":"24","author":"J Song","year":"2018","unstructured":"Song, J. et al. A new approach to predict Progression-free survival in stage IV EGFR-mutant NSCLC patients with EGFR-TKI therapy. Clin. Cancer Res. 24 (15), 3583\u20133592 (2018).","journal-title":"Clin. Cancer Res."},{"issue":"7","key":"9115_CR16","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1016\/j.annonc.2020.04.003","volume":"31","author":"D Dong","year":"2020","unstructured":"Dong, D. et al. Deep learning radiomic nomogram can predict the number of lymph node metastasis in locally advanced gastric cancer: an international multicenter study. Ann. Oncol. 31 (7), 912\u2013920 (2020).","journal-title":"Ann. Oncol."},{"issue":"5","key":"9115_CR17","doi-asserted-by":"publisher","first-page":"e340","DOI":"10.1016\/S2589-7500(22)00040-1","volume":"4","author":"Y Jiang","year":"2022","unstructured":"Jiang, Y. et al. Predicting peritoneal recurrence and disease-free survival from CT images in gastric cancer with multitask deep learning: a retrospective study. Lancet Digit. Health. 4 (5), e340\u2013e50 (2022).","journal-title":"Lancet Digit. Health"},{"key":"9115_CR18","doi-asserted-by":"publisher","first-page":"l4225","DOI":"10.1136\/bmj.l4225","volume":"366","author":"SM Fernando","year":"2019","unstructured":"Fernando, S. M. et al. Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis. BMJ 366, l4225 (2019).","journal-title":"BMJ"},{"issue":"2","key":"9115_CR19","doi-asserted-by":"publisher","first-page":"514","DOI":"10.3171\/2019.4.JNS183297","volume":"133","author":"J Wang","year":"2020","unstructured":"Wang, J. et al. Ultrasonographic optic nerve sheath diameter correlation with ICP and accuracy as a tool for noninvasive surrogate ICP measurement in patients with decompressive craniotomy. J. Neurosurg. 133 (2), 514\u2013520 (2020).","journal-title":"J. Neurosurg."},{"issue":"2","key":"9115_CR20","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1007\/s12028-023-01711-7","volume":"39","author":"X Xu","year":"2023","unstructured":"Xu, X. et al. Diagnostic value of the combination of ultrasonographic optic nerve sheath diameter and width of crural cistern with respect to the intracranial pressure in patients treated with decompressive craniotomy. Neurocrit Care. 39 (2), 436\u2013444 (2023).","journal-title":"Neurocrit Care"},{"key":"9115_CR21","doi-asserted-by":"publisher","first-page":"111312","DOI":"10.1016\/j.jclinane.2023.111312","volume":"92","author":"M Rondagh","year":"2024","unstructured":"Rondagh, M. et al. A comparison of ultrafast and conventional spectral doppler ultrasound to measure cerebral blood flow velocity during inguinal hernia repair in infants. J. Clin. Anesth. 92, 111312 (2024).","journal-title":"J. Clin. Anesth."},{"issue":"3","key":"9115_CR22","doi-asserted-by":"publisher","first-page":"386","DOI":"10.3171\/jns.1995.82.3.0386","volume":"82","author":"M Yoshihara","year":"1995","unstructured":"Yoshihara, M., Bandoh, K. & Marmarou, A. Cerebrovascular carbon dioxide reactivity assessed by intracranial pressure dynamics in severely head injured patients. J. Neurosurg. 82 (3), 386\u2013393 (1995).","journal-title":"J. Neurosurg."},{"issue":"7223","key":"9115_CR23","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1038\/nature07525","volume":"456","author":"GR Gordon","year":"2008","unstructured":"Gordon, G. R. et al. Brain metabolism dictates the Polarity of astrocyte control over arterioles. Nature 456 (7223), 745\u2013749 (2008).","journal-title":"Nature"},{"issue":"1","key":"9115_CR24","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3174\/ajnr.A7721","volume":"44","author":"JC Benson","year":"2023","unstructured":"Benson, J. C. et al. The Monro-Kellie doctrine: A review and call for revision. AJNR Am. J. Neuroradiol. 44 (1), 2\u20136 (2023).","journal-title":"AJNR Am. J. Neuroradiol."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-09115-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-09115-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-09115-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T15:01:07Z","timestamp":1751468467000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-09115-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,2]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["9115"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-09115-7","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,2]]},"assertion":[{"value":"10 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study was conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committee of the Second affiliated Hospital of Shandong First Medical University (2021-A-037).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"All authors agree to publish this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"23595"}}