{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:09:49Z","timestamp":1793725789196,"version":"4.6.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the General Programme of Social Science Foundation of Fujian Province","award":["NO.FJ2024B092"],"award-info":[{"award-number":["NO.FJ2024B092"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-11196-3","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T12:34:10Z","timestamp":1753187650000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of blood flow restricted staircase sprint snacks on body composition, anaerobic power, and muscle strength in physically inactive students"],"prefix":"10.1038","volume":"15","author":[{"given":"Ji","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"issue":"2","key":"11196_CR1","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1002\/cphy.c110025","volume":"2","author":"FW Booth","year":"2012","unstructured":"Booth, F. W., Roberts, C. K. & Laye, M. J. Lack of exercise is a major cause of chronic diseases. Compr. Physiol. 2 (2), 1143\u20131211. https:\/\/doi.org\/10.1002\/cphy.c110025 (2012).","journal-title":"Compr. Physiol."},{"issue":"24","key":"11196_CR2","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","volume":"54","author":"FC Bull","year":"2020","unstructured":"Bull, F. C. et al. World health organization 2020 guidelines on physical activity and sedentary behaviour. Br. J. Sports Med. 54 (24), 1451\u20131462. https:\/\/doi.org\/10.1136\/bjsports-2020-102955 (2020).","journal-title":"Br. J. Sports Med."},{"issue":"8","key":"11196_CR3","doi-asserted-by":"publisher","first-page":"e1232","DOI":"10.1016\/S2214-109X(24)00150-5","volume":"12","author":"T Strain","year":"2024","unstructured":"Strain, T. et al. National, regional, and global trends in insufficient physical activity among adults from 2000 to 2022: a pooled analysis of 507 population-based surveys with 5\u00b77 million participants. Lancet Glob Health. 12 (8), e1232\u2013e1243. https:\/\/doi.org\/10.1016\/S2214-109X(24)00150-5 (2024).","journal-title":"Lancet Glob Health"},{"key":"11196_CR4","doi-asserted-by":"publisher","unstructured":"Garcia, L. et al. Barriers and facilitators of domain-specific physical activity: a systematic review of reviews. BMC Public Health. 22,1964(2022).https:\/\/doi.org\/10.1186\/s12889-022-14385-1","DOI":"10.1186\/s12889-022-14385-1"},{"key":"11196_CR5","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1136\/bjsports-2014-094306","volume":"49","author":"D Hupin","year":"2015","unstructured":"Hupin, D. et al. Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged\u2009\u2265\u200960 years: a systematic review and meta-analysis. Br. J. Sports Med. 49, 1262\u20131267. https:\/\/doi.org\/10.1136\/bjsports-2014-094306 (2015).","journal-title":"Br. J. Sports Med."},{"key":"11196_CR6","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1249\/MSS.0000000000001933","volume":"51","author":"JM Jakicic","year":"2019","unstructured":"Jakicic, J. M. et al. Association between bout duration of physical activity and health: systematic review. Med. Sci. Sports Exerc. 51, 1213\u20131219. https:\/\/doi.org\/10.1249\/MSS.0000000000001933 (2019).","journal-title":"Med. Sci. Sports Exerc."},{"issue":"1","key":"11196_CR7","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1249\/JES.0000000000000275","volume":"50","author":"H Islam","year":"2022","unstructured":"Islam, H., Gibala, M. J. & Little, J. P. Exercise snacks: A novel strategy to improve cardiometabolic health. Exerc. Sport Sci. Rev. 50 (1), 31\u201337. https:\/\/doi.org\/10.1249\/JES.0000000000000275 (2022).","journal-title":"Exerc. Sport Sci. Rev."},{"key":"11196_CR8","doi-asserted-by":"publisher","unstructured":"Jenkins, E. M., Nairn, L. N., Skelly, L. E., Little, J. P. & Gibala, M. J.Do stair climbing exercise snacks improve cardiorespiratory fitness? Applied physiology, nutrition, and metabolism\u2009=\u2009Physiologie appliquee, nutrition et metabolisme.44(6), 681\u2013684 (2019). https:\/\/doi.org\/10.1139\/apnm-2018-0675","DOI":"10.1139\/apnm-2018-0675"},{"issue":"7","key":"11196_CR9","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1139\/apnm-2023-0593","volume":"49","author":"M Yin","year":"2024","unstructured":"Yin, M. et al. Exercise snacks are a time-efficient alternative to moderate-intensity continuous training for improving cardiorespiratory fitness but not maximal fat oxidation in inactive adults: a randomized controlled trial. Appl. Physiol. Nutr. Metab. 49 (7), 920\u2013932. https:\/\/doi.org\/10.1139\/apnm-2023-0593 (2024).","journal-title":"Appl. Physiol. Nutr. Metab."},{"issue":"5","key":"11196_CR10","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1139\/apnm-2020-0562","volume":"46","author":"HG Caldwell","year":"2021","unstructured":"Caldwell, H. G., Coombs, G. B., Rafiei, H., Ainslie, P. N. & Little, J. P. Hourly staircase sprinting exercise snacks improve femoral artery shear patterns but not flow-mediated dilation or cerebrovascular regulation: a pilot study. Appl. Physiol. Nutr. Metab. 46 (5), 521\u2013529. https:\/\/doi.org\/10.1139\/apnm-2020-0562 (2021).","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"11196_CR11","doi-asserted-by":"publisher","unstructured":"Perkin, O. J., McGuigan, P. M. & Stokes, K. A. Exercise snacking to improve muscle function in healthy older adults: A pilot study. J. Aging Res. 7516939 (2019). https:\/\/doi.org\/10.1155\/2019\/7516939 (2019).","DOI":"10.1155\/2019\/7516939"},{"issue":"13","key":"11196_CR12","doi-asserted-by":"publisher","first-page":"4860","DOI":"10.3390\/ijerph17134860","volume":"17","author":"CH Wun","year":"2020","unstructured":"Wun, C. H. et al. R.Efficacy of a Six-Week dispersed Wingate-Cycle training protocol on peak aerobic power, leg strength, insulin sensitivity, blood lipids and quality of life in healthy adults. Int. J. Environ. Res. Public Health. 17 (13), 4860. https:\/\/doi.org\/10.3390\/ijerph17134860 (2020).","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"11196_CR13","doi-asserted-by":"publisher","first-page":"1861","DOI":"10.1007\/s00421-023-05411-0","volume":"124","author":"PY Wong","year":"2024","unstructured":"Wong, P. Y. et al. A single all-out bout of 30-s sprint-cycle performed on 5 consecutive days per week over 6 weeks does not enhance cardiovascular fitness, maximal strength, and clinical health markers in physically active young adults. Eur. J. Appl. Physiol. 124, 1861\u20131874. https:\/\/doi.org\/10.1007\/s00421-023-05411-0 (2024).","journal-title":"Eur. J. Appl. Physiol."},{"issue":"2","key":"11196_CR14","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1507\/endocrj.EJ24-0377","volume":"72","author":"J Zhou","year":"2025","unstructured":"Zhou, J., Gao, X., Zhang, D., Jiang, C. & Yu W.Effects of breaking up prolonged sitting via exercise snacks intervention on the body composition and plasma metabolomics of sedentary obese adults: a randomized controlled trial. Endocr. J. 72 (2), 183\u2013192. https:\/\/doi.org\/10.1507\/endocrj.EJ24-0377 (2025).","journal-title":"Endocr. J."},{"key":"11196_CR15","doi-asserted-by":"publisher","first-page":"2199","DOI":"10.1007\/s40279-024-02080-7","volume":"54","author":"M Yin","year":"2024","unstructured":"Yin, M. et al. Comment on exercise snacks and other forms of intermittent physical activity for improving health in adults and older adults: A scoping review of epidemiological, experimental and qualitative studies. Sports Med. 54, 2199\u20132203. https:\/\/doi.org\/10.1007\/s40279-024-02080-7 (2024).","journal-title":"Sports Med."},{"key":"11196_CR16","doi-asserted-by":"publisher","unstructured":"Patterson, S. D. et al. Blood flow restriction exercise: considerations of methodology, application, and safety. Front. Physiol. 10 https:\/\/doi.org\/10.3389\/fphys.2019.00533 (2019).","DOI":"10.3389\/fphys.2019.00533"},{"issue":"9","key":"11196_CR17","doi-asserted-by":"publisher","first-page":"2462","DOI":"10.1519\/JSC.0000000000001746","volume":"31","author":"M Behringer","year":"2017","unstructured":"Behringer, M., Behlau, D., Montag, J. C. K., McCourt, M. L. & Mester, J. Low-Intensity sprint training with blood flow restriction improves 100-m Dash. J. Strength. Cond Res. 31 (9), 2462\u20132472. https:\/\/doi.org\/10.1519\/JSC.0000000000001746 (2017).","journal-title":"J. Strength. Cond Res."},{"issue":"2","key":"11196_CR18","first-page":"374","volume":"19","author":"S Amani-Shalamzari","year":"2020","unstructured":"Amani-Shalamzari, S. et al. Occlusion training during specific futsal training improves aspects of physiological and physical performance. J. Sports Sci. Med. 19 (2), 374\u2013382 (2020).","journal-title":"J. Sports Sci. Med."},{"issue":"9","key":"11196_CR19","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1055\/a-0888-8816","volume":"40","author":"P Fatela","year":"2019","unstructured":"Fatela, P., Mendonca, G. V., Veloso, A. P., Avela, J. & Mil-Homens, P. Blood flow restriction alters motor unit behavior during resistance exercise. Int. J. Sports Med. 40 (9), 555\u2013562. https:\/\/doi.org\/10.1055\/a-0888-8816 (2019).","journal-title":"Int. J. Sports Med."},{"issue":"2","key":"11196_CR20","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/s00421-014-3030-7","volume":"115","author":"JP Loenneke","year":"2015","unstructured":"Loenneke, J. P. et al. Blood flow restriction in the upper and lower limbs is predicted by limb circumference and systolic blood pressure. Eur. J. Appl. Physiol. 115 (2), 397\u2013405. https:\/\/doi.org\/10.1007\/s00421-014-3030-7 (2015).","journal-title":"Eur. J. Appl. Physiol."},{"issue":"8","key":"11196_CR21","doi-asserted-by":"publisher","first-page":"2367","DOI":"10.1519\/JSC.0000000000000216","volume":"29","author":"WR Lunn","year":"2015","unstructured":"Lunn, W. R., Zenoni, M. A., Crandall, I. H., Dress, A. E. & Berglund, M. L. Lower wingate test power outcomes from All-Out pretest pedaling Cadence compared with moderate Cadence. J. Strength. Cond Res. 29 (8), 2367\u20132373. https:\/\/doi.org\/10.1519\/JSC.0000000000000216 (2015).","journal-title":"J. Strength. Cond Res."},{"issue":"1","key":"11196_CR22","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1186\/s12877-022-03648-6","volume":"22","author":"MPB De Oliveira","year":"2022","unstructured":"De Oliveira, M. P. B. et al. L. P. Reproducibility of isokinetic measures of the knee and ankle muscle strength in community-dwelling older adults without and with alzheimer\u2019s disease. BMC Geriatr. 22 (1), 940. https:\/\/doi.org\/10.1186\/s12877-022-03648-6 (2022).","journal-title":"BMC Geriatr."},{"issue":"5","key":"11196_CR23","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/s1050-6411(00)00027-4","volume":"10","author":"HJ Hermens","year":"2000","unstructured":"Hermens, H. J., Freriks, B., Disselhorst-Klug, C. & Rau, G. Development of recommendations for SEMG sensors and sensor placement procedures. J. Electromyogr. Kinesiol. 10 (5), 361\u2013374. https:\/\/doi.org\/10.1016\/s1050-6411(00)00027-4 (2000).","journal-title":"J. Electromyogr. Kinesiol."},{"key":"11196_CR24","unstructured":"Cohen, J. Statistical Power Analysis for the Behavioral Sciences Hillsdale (Lawrence Erlbaum Associates,, 1988)."},{"key":"11196_CR25","doi-asserted-by":"publisher","unstructured":"Herda, A. A. et al. Blood flow restriction during walking does not impact body composition or performance measures in highly trained runners. J. Funct. Morphology Kinesiol. 9 (2). https:\/\/doi.org\/10.3390\/jfmk9020074 (2024).","DOI":"10.3390\/jfmk9020074"},{"issue":"12","key":"11196_CR26","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.3390\/life14121666","volume":"14","author":"H Chang","year":"2024","unstructured":"Chang, H., Yang, X., Chen, B. & Zhang, J. Effects of different blood flow restriction training modes on body composition and maximal strength of untrained individuals. Life (Basel Switzerland). 14 (12), 1666. https:\/\/doi.org\/10.3390\/life14121666 (2024).","journal-title":"Life (Basel Switzerland)"},{"issue":"4","key":"11196_CR27","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1159\/000505328","volume":"92","author":"R Hasan","year":"2019","unstructured":"Hasan, R. et al. Can short bouts of exercise (Exercise Snacks) improve body composition in adolescents with type 1 diabetes?? A feasibility study. Horm. Res. Paediatr. 92 (4), 245\u2013253. https:\/\/doi.org\/10.1159\/000505328 (2019).","journal-title":"Horm. Res. Paediatr."},{"issue":"3","key":"11196_CR28","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1249\/MSS.0000000000001475","volume":"50","author":"F Husmann","year":"2018","unstructured":"Husmann, F., Mittlmeier, T., Bruhn, S., Zschorlich, V. & Behrens, M. Impact of blood flow restriction exercise on muscle fatigue development and recovery. Med. Sci. Sports. Exerc. 50 (3), 436\u2013446. https:\/\/doi.org\/10.1249\/MSS.0000000000001475 (2018).","journal-title":"Med. Sci. Sports. Exerc."},{"issue":"3","key":"11196_CR29","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1111\/cpf.12141","volume":"35","author":"CA Fahs","year":"2015","unstructured":"Fahs, C. A. et al. Muscular adaptations to fatiguing exercise with and without blood flow restriction. Clin. Physiol. Funct. Imaging. 35 (3), 167\u2013176. https:\/\/doi.org\/10.1111\/cpf.12141 (2015).","journal-title":"Clin. Physiol. Funct. Imaging"},{"key":"11196_CR30","doi-asserted-by":"publisher","first-page":"663665","DOI":"10.3389\/fphys.2021.663665","volume":"12","author":"C Schwiete","year":"2021","unstructured":"Schwiete, C., Franz, A., Roth, C. & Behringer, M. Effects of resting vs. Continuous Blood-Flow Restriction-Training on strength, fatigue resistance, muscle thickness, and perceived discomfort. Front. Physiol. 12, 663665. https:\/\/doi.org\/10.3389\/fphys.2021.663665 (2021).","journal-title":"Front. Physiol."},{"key":"11196_CR31","doi-asserted-by":"crossref","unstructured":"Amani-Shalamzari, S. et al. B.Effects of blood flow restriction and exercise intensity on aerobic, anaerobic, and muscle strength adaptations in physically active collegiate women. Front. Physiol. 10, 810. https:\/\/doi.org\/10.3389\/fphys.2019.00810 (2019).","DOI":"10.3389\/fphys.2019.00810"},{"key":"11196_CR32","doi-asserted-by":"crossref","unstructured":"Amani-Shalamzari, S. et al. Blood flow restriction during futsal training increases muscle activation and strength. Front. Physiol. 10, 614. https:\/\/doi.org\/10.3389\/fphys.2019.00614 (2019).","DOI":"10.3389\/fphys.2019.00614"},{"issue":"1","key":"11196_CR33","first-page":"34","volume":"33","author":"T Abe","year":"2010","unstructured":"Abe, T. et al. Effects of low-intensity walk training with restricted leg blood flow on muscle strength and aerobic capacity in older adults. J. Geriatric Phys. Therapy (2001). 33 (1), 34\u201340 (2010).","journal-title":"J. Geriatric Phys. Therapy (2001)"},{"issue":"9","key":"11196_CR34","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1111\/sms.12540","volume":"26","author":"MF de Oliveira","year":"2016","unstructured":"de Oliveira, M. F., Caputo, F., Corvino, R. B. & Denadai, B. S. Short-term low-intensity blood flow restricted interval training improves both aerobic fitness and muscle strength. Scand. J. Med. Sci. Sports. 26 (9), 1017\u20131025. https:\/\/doi.org\/10.1111\/sms.12540 (2016).","journal-title":"Scand. J. Med. Sci. Sports"},{"issue":"8","key":"11196_CR35","doi-asserted-by":"publisher","first-page":"2903","DOI":"10.1007\/s00421-011-2266-8","volume":"112","author":"JP Loenneke","year":"2012","unstructured":"Loenneke, J. P. et al. Effects of cuff width on arterial occlusion: implications for blood flow restricted exercise. Eur. J. Appl. Physiol. 112 (8), 2903\u20132912. https:\/\/doi.org\/10.1007\/s00421-011-2266-8 (2012).","journal-title":"Eur. J. Appl. Physiol."},{"issue":"1","key":"11196_CR36","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.mehy.2011.10.014","volume":"78","author":"JP Loenneke","year":"2012","unstructured":"Loenneke, J. P., Fahs, C. A., Rossow, L. M., Abe, T. & Bemben, M. G. The anabolic benefits of venous blood flow restriction training May be induced by muscle cell swelling. Med. Hypotheses. 78 (1), 151\u2013154. https:\/\/doi.org\/10.1016\/j.mehy.2011.10.014 (2012).","journal-title":"Med. Hypotheses"},{"key":"11196_CR37","doi-asserted-by":"publisher","unstructured":"Jessee, M. B., Mattocks, K. T., Buckner, S. L., Dankel, S. J., Mouser, J. G., Abe, T., & Loenneke, J. P. (2018). Mechanisms of blood flow restriction: The new testament. Techniques in Orthopaedics, 33(2), 72\u201379. https:\/\/doi.org\/10.1097\/BTO.0000000000000252","DOI":"10.1097\/BTO.0000000000000252"},{"issue":"10","key":"11196_CR38","doi-asserted-by":"publisher","first-page":"2914","DOI":"10.1519\/JSC.0b013e3182874721","volume":"27","author":"ZK Pope","year":"2013","unstructured":"Pope, Z. K., Willardson, J. M. & Schoenfeld, B. J. Exercise and blood flow restriction. J. Strength. Cond Res. 27 (10), 2914\u20132926 (2013).","journal-title":"J. Strength. Cond Res."},{"issue":"4","key":"11196_CR39","first-page":"444","volume":"53","author":"KE Labarbera","year":"2013","unstructured":"Labarbera, K. E., Murphy, B. G., Laroche, D. P. & Cook, S. B. Sex differences in blood flow restricted isotonic knee extensions to fatigue. J. Sports Med. Phys. Fit. 53 (4), 444\u2013452 (2013).","journal-title":"J. Sports Med. Phys. Fit."},{"issue":"1","key":"11196_CR40","doi-asserted-by":"publisher","first-page":"e0301164","DOI":"10.1371\/journal.pone.0301164","volume":"20","author":"D Nancekievill","year":"2025","unstructured":"Nancekievill, D., Seaman, K., Bouchard, D. R., Thomson, A. M. & S\u00e9n\u00e9chal, M. Impact of exercise with blood flow restriction on muscle hypertrophy and performance outcomes in men and women. PloS One. 20 (1), e0301164. https:\/\/doi.org\/10.1371\/journal.pone.0301164 (2025).","journal-title":"PloS One"},{"issue":"1","key":"11196_CR41","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1111\/j.1600-0838.2012.01489.x","volume":"24","author":"T Yasuda","year":"2014","unstructured":"Yasuda, T. et al. Effects of low-intensity, elastic band resistance exercise combined with blood flow restriction on muscle activation. Scand. J. Med. Sci. Sports. 24 (1), 55\u201361. https:\/\/doi.org\/10.1111\/j.1600-0838.2012.01489.x (2014).","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"11196_CR42","doi-asserted-by":"publisher","first-page":"1446963","DOI":"10.3389\/fphys.2024.1446963","volume":"15","author":"VS de Queiros","year":"2024","unstructured":"de Queiros, V. S. et al. Body position and cuff size influence lower limb arterial occlusion pressure and its predictors: implications for standardizing the pressure applied in training with blood flow restriction. Front. Physiol. 15, 1446963. https:\/\/doi.org\/10.3389\/fphys.2024.1446963 (2024).","journal-title":"Front. Physiol."},{"issue":"9","key":"11196_CR43","doi-asserted-by":"publisher","first-page":"2693","DOI":"10.1519\/JSC.0000000000002665","volume":"34","author":"GC Laurentino","year":"2020","unstructured":"Laurentino, G. C. et al. Validity of the handheld doppler to determine Lower-Limb blood flow restriction pressure for exercise protocols. J. Strength. Conditioning Res. 34 (9), 2693\u20132696. https:\/\/doi.org\/10.1519\/JSC.0000000000002665 (2020).","journal-title":"J. Strength. Conditioning Res."},{"issue":"4","key":"11196_CR44","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1519\/JSC.0000000000003628","volume":"36","author":"F Lima-Soares","year":"2022","unstructured":"Lima-Soares, F. et al. Determining the arterial occlusion pressure for blood flow restriction: pulse oximeter as a new method compared with a handheld doppler. J. Strength. Conditioning Res. 36 (4), 1120\u20131124. https:\/\/doi.org\/10.1519\/JSC.0000000000003628 (2022).","journal-title":"J. Strength. Conditioning Res."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11196-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11196-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11196-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T17:50:15Z","timestamp":1757267415000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11196-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,22]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["11196"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-11196-3","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,22]]},"assertion":[{"value":"18 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"26610"}}