{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:26:37Z","timestamp":1791365197536,"version":"4.3.1"},"reference-count":99,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100004621","name":"Kerman University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-11532-7","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T08:51:55Z","timestamp":1752655915000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Microwave assisted solvothermal green synthesis of Fe3O4 nanoparticles using sea buckthorn for multiple myeloma and monocytic leukemia treatment"],"prefix":"10.1038","volume":"15","author":[{"given":"Asaad H.","family":"Alzaidy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safaa H.","family":"Ganduh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"May Jaleel","family":"Abed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmuez A.","family":"Dawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Layth S.","family":"Jasim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Hossein","family":"Ashoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,16]]},"reference":[{"key":"11532_CR1","doi-asserted-by":"publisher","first-page":"891652","DOI":"10.3389\/fonc.2022.891652","volume":"12","author":"TB Emran","year":"2022","unstructured":"Emran, T. B. et al. Multidrug resistance in cancer: Understanding molecular mechanisms, Immunoprevention and therapeutic approaches. Front. Oncol. 12, 891652 (2022).","journal-title":"Front. Oncol."},{"issue":"13","key":"11532_CR2","doi-asserted-by":"publisher","first-page":"2478","DOI":"10.3390\/cancers16132478","volume":"16","author":"P Garg","year":"2024","unstructured":"Garg, P. et al. Emerging therapeutic strategies to overcome drug resistance in cancer cells. Cancers 16 (13), 2478 (2024).","journal-title":"Cancers"},{"issue":"1","key":"11532_CR3","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1186\/s40001-024-01822-7","volume":"29","author":"MH Ashoub","year":"2024","unstructured":"Ashoub, M. H., Razavi, R., Heydaryan, K., Salavati-Niasari, M. & Amiri, M. Targeting ferroptosis for leukemia therapy: exploring novel strategies from its mechanisms and role in leukemia based on nanotechnology. Eur. J. Med. Res. 29 (1), 224 (2024).","journal-title":"Eur. J. Med. Res."},{"issue":"1","key":"11532_CR4","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1186\/s40001-023-01429-4","volume":"28","author":"F Abaszadeh","year":"2023","unstructured":"Abaszadeh, F., Ashoub, M. H., Khajouie, G. & Amiri, M. Nanotechnology development in surgical applications: recent trends and developments. Eur. J. Med. Res. 28 (1), 537 (2023).","journal-title":"Eur. J. Med. Res."},{"key":"11532_CR5","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/978-981-99-5398-1_13","volume-title":"Current Trends in Green Nano-emulsions: Food, Agriculture and Biomedical Sectors","author":"F Abaszadeh","year":"2023","unstructured":"Abaszadeh, F., Ashoub, M. H. & Amiri, M. Nanoemulsions challenges and future prospects as a drug delivery system. In Current Trends in Green Nano-emulsions: Food, Agriculture and Biomedical Sectors (eds Husen, A. et al.) 217\u2013243 (Springer Nature Singapore, 2023)."},{"issue":"1","key":"11532_CR6","first-page":"3","volume":"9","author":"SA Padala","year":"2021","unstructured":"Padala, S. A. et al. Epidemiology, staging, and management of multiple myeloma. Med. Sci. 9 (1), 3 (2021).","journal-title":"Med. Sci."},{"issue":"5","key":"11532_CR7","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1001\/jama.2022.0003","volume":"327","author":"AJ Cowan","year":"2022","unstructured":"Cowan, A. J. et al. Diagnosis and management of multiple myeloma: a review. Jama 327 (5), 464\u2013477 (2022).","journal-title":"Jama"},{"issue":"3","key":"11532_CR8","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1182\/blood.V77.3.587.587","volume":"77","author":"G Schwab","year":"1991","unstructured":"Schwab, G., Siegall, C. B., Aarden, L. A., Neckers, L. M. & Nordan, R. P. Characterization of an Interleukin-6-Mediated autocrine growth loop in the human multiple myeloma cell line, U266. Blood 77 (3), 587\u2013593 (1991).","journal-title":"Blood"},{"key":"11532_CR9","doi-asserted-by":"publisher","first-page":"911093","DOI":"10.3389\/fped.2022.911093","volume":"10","author":"E Varotto","year":"2022","unstructured":"Varotto, E., Munaretto, E., Stefanachi, F., Della Torre, F. & Buldini, B. Diagnostic challenges in acute monoblastic\/monocytic leukemia in children. Front. Pead. 10, 911093 (2022).","journal-title":"Front. Pead."},{"key":"11532_CR10","doi-asserted-by":"crossref","unstructured":"Ren, J. et al. The potential use of THP-1, a monocytic leukemia cell line, to predict Immune-Suppressive potency of human Bone-Marrow stromal cells (BMSCs) in vitro: A pilot study. Int. J. Mol. Sci. 24(17), 13258 (2023).","DOI":"10.3390\/ijms241713258"},{"issue":"1","key":"11532_CR11","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1007\/BF02041244","volume":"47","author":"J Auwerx","year":"1991","unstructured":"Auwerx, J. The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte-macrophage differentiation. Experientia 47 (1), 22\u201331 (1991).","journal-title":"Experientia"},{"issue":"17","key":"11532_CR12","doi-asserted-by":"publisher","first-page":"4280","DOI":"10.3390\/molecules29174280","volume":"29","author":"JJ Lica","year":"2024","unstructured":"Lica, J. J., Pradhan, B., Safi, K., Jak\u00f3bkiewicz-Banecka, J. & Hellmann, A. Promising therapeutic strategies for hematologic malignancies: innovations and potential. Molecules 29 (17), 4280 (2024).","journal-title":"Molecules"},{"issue":"4","key":"11532_CR13","doi-asserted-by":"publisher","first-page":"777","DOI":"10.2174\/0929867327666200123152006","volume":"28","author":"S Hooshmand","year":"2021","unstructured":"Hooshmand, S. et al. Preparation and applications of superparamagnetic iron oxide nanoparticles in novel drug delivery systems: an overview. Curr. Med. Chem. 28 (4), 777\u2013799 (2021).","journal-title":"Curr. Med. Chem."},{"key":"11532_CR14","doi-asserted-by":"crossref","unstructured":"Ashoub, M. H., Amiri, M. & Khajouei, G. in Chapter 5 - Fe3O4-based Nanofluids. 101\u2013127 (eds Rashidi, M. M. & Zinatloo-Ajabshir, S.) (Elsevier, 2024).","DOI":"10.1016\/B978-0-443-13625-2.00013-9"},{"key":"11532_CR15","doi-asserted-by":"crossref","unstructured":"Gour, A. & Jain, N. K. Advances in green synthesis of nanoparticles. Artificial cells, nanomedicine, and biotechnology. 47(1), 844\u2013851 (2019).","DOI":"10.1080\/21691401.2019.1577878"},{"key":"11532_CR16","doi-asserted-by":"crossref","unstructured":"de Conti, M., Dey, S., Pottker, W. & La Porta, F. A. An overview into advantages and applications of conventional and unconventional hydro (solvo) thermal approaches for novel advanced materials design. (2022).","DOI":"10.26434\/chemrxiv-2022-scxdh"},{"issue":"2","key":"11532_CR17","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.physb.2010.10.017","volume":"406","author":"A Aslani","year":"2011","unstructured":"Aslani, A. Controlling the morphology and size of CuO nanostructures with synthesis by solvo\/hydrothermal method without any additives. Phys. B: Condens. Matter. 406 (2), 150\u2013154 (2011).","journal-title":"Phys. B: Condens. Matter"},{"key":"11532_CR18","doi-asserted-by":"publisher","first-page":"104899","DOI":"10.1016\/j.ultsonch.2019.104899","volume":"62","author":"S Gholamrezaei","year":"2020","unstructured":"Gholamrezaei, S., Amiri, M., Amiri, O., Salavati-Niasari, M. & Moayedi, H. Ultrasound-accelerated synthesis of uniform SrMnO3 nanoparticles as water-oxidizing catalysts for water splitting systems. Ultrason. Sonochem. 62, 104899 (2020).","journal-title":"Ultrason. Sonochem."},{"issue":"1","key":"11532_CR19","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1007\/s10311-020-01074-x","volume":"19","author":"S Jadoun","year":"2021","unstructured":"Jadoun, S., Arif, R., Jangid, N. K. & Meena, R. K. Green synthesis of nanoparticles using plant extracts: A review. Environ. Chem. Lett. 19 (1), 355\u2013374 (2021).","journal-title":"Environ. Chem. Lett."},{"key":"11532_CR20","doi-asserted-by":"crossref","unstructured":"Ashoub, M. H., Amiri, M., Fatemi, A. & Farsinejad, A. Evaluation of ferroptosis-based anti-leukemic activities of ZnO nanoparticles synthesized by a green route against Pre-B acute lymphoblastic leukemia cells (Nalm-6 and REH). Heliyon. 10(17), e36608 (2024).","DOI":"10.1016\/j.heliyon.2024.e36608"},{"key":"11532_CR21","doi-asserted-by":"crossref","unstructured":"Hamzeh, S., Mahmoudi-Moghaddam, H., Zinatloo-Ajabshir, S., Amiri, M. & Azari, A. Simple fabrication of mesoporous Praseodymium cerate via an eco-friendly route for development of carbendazim electrochemical sensor. J. Electrochem. Soc. 171(3), 037508 (2024).","DOI":"10.1149\/1945-7111\/ad2cb8"},{"issue":"5","key":"11532_CR22","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.3390\/molecules25051170","volume":"25","author":"A Criste","year":"2020","unstructured":"Criste, A. et al. Phytochemical composition and biological activity of berries and leaves from four Romanian sea Buckthorn (Hippophae rhamnoides L.) varieties. Molecules 25 (5), 1170 (2020).","journal-title":"Molecules"},{"key":"11532_CR23","doi-asserted-by":"publisher","first-page":"1246728","DOI":"10.3389\/fmolb.2023.1246728","volume":"10","author":"P Dadhwal","year":"2023","unstructured":"Dadhwal, P. et al. Hippophae rhamnoides L.(sea buckthorn) mediated green synthesis of copper nanoparticles and their application in anticancer activity. Front. Mol. Biosci. 10, 1246728 (2023).","journal-title":"Front. Mol. Biosci."},{"issue":"1","key":"11532_CR24","doi-asserted-by":"publisher","first-page":"22","DOI":"10.55705\/cmbr.2022.330326.1020","volume":"2","author":"H Ahani","year":"2022","unstructured":"Ahani, H. & Attaran, S. Therapeutic potential of Seabuckthorn (Hippophae rhamnoides L.) in medical sciences. Cell. Mol. Biomedical Rep. 2 (1), 22\u201332 (2022).","journal-title":"Cell. Mol. Biomedical Rep."},{"key":"11532_CR25","doi-asserted-by":"publisher","first-page":"1036295","DOI":"10.3389\/fnut.2022.1036295","volume":"9","author":"Z Wang","year":"2022","unstructured":"Wang, Z. et al. Phytochemistry, health benefits, and food applications of sea Buckthorn (Hippophae rhamnoides L.): A comprehensive review. Front. Nutr. 9, 1036295 (2022).","journal-title":"Front. Nutr."},{"key":"11532_CR26","doi-asserted-by":"publisher","first-page":"102941","DOI":"10.1016\/j.jddst.2021.102941","volume":"67","author":"Z Dehghan","year":"2022","unstructured":"Dehghan, Z., Ranjbar, M., Govahi, M. & Khakdan, F. Green synthesis of Ag\/Fe3O4 nanocomposite utilizing Eryngium planum L. leaf extract and its potential applications in medicine. J. Drug Deliv. Sci. Technol. 67, 102941 (2022).","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"11532_CR27","doi-asserted-by":"crossref","unstructured":"Wang, L., Karmakar, B., Al-Saeed, F. A., Bani-Fwaz, M. Z. & El-kott, A. F. Green synthesis of Ag\/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects. Heliyon. 8(12), e12326 (2022).","DOI":"10.1016\/j.heliyon.2022.e12326"},{"issue":"3","key":"11532_CR28","doi-asserted-by":"publisher","first-page":"686","DOI":"10.3390\/nu15030686","volume":"15","author":"N S\u0142awi\u0144ska","year":"2023","unstructured":"S\u0142awi\u0144ska, N., \u017buchowski, J., Stochmal, A. & Olas, B. Extract from sea Buckthorn seeds\u2014a phytochemical, antioxidant, and hemostasis study; effect of thermal processing on its chemical content and biological activity in vitro. Nutrients 15 (3), 686 (2023).","journal-title":"Nutrients"},{"key":"11532_CR29","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1016\/j.foodchem.2016.11.063","volume":"221","author":"R Guo","year":"2017","unstructured":"Guo, R., Guo, X., Li, T., Fu, X. & Liu, R. H. Comparative assessment of phytochemical profiles, antioxidant and antiproliferative activities of sea Buckthorn (Hippopha\u00eb rhamnoides L.) berries. Food Chem. 221, 997\u20131003 (2017).","journal-title":"Food Chem."},{"issue":"1","key":"11532_CR30","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3390\/ph17010023","volume":"17","author":"N Tritean","year":"2023","unstructured":"Tritean, N. et al. Cytocompatibility, antimicrobial and antioxidant activity of a mucoadhesive biopolymeric hydrogel embedding selenium nanoparticles phytosynthesized by sea Buckthorn leaf extract. Pharmaceuticals 17 (1), 23 (2023).","journal-title":"Pharmaceuticals"},{"issue":"22","key":"11532_CR31","doi-asserted-by":"publisher","first-page":"9304","DOI":"10.1039\/D0NJ01335H","volume":"44","author":"S Wei","year":"2020","unstructured":"Wei, S. et al. A size-controlled green synthesis of silver nanoparticles by using the berry extract of sea Buckthorn and their biological activities. New J. Chem. 44 (22), 9304\u20139312 (2020).","journal-title":"New J. Chem."},{"issue":"1","key":"11532_CR32","doi-asserted-by":"publisher","first-page":"3083","DOI":"10.1038\/s41598-025-85329-z","volume":"15","author":"MH Ashoub","year":"2025","unstructured":"Ashoub, M. H. et al. siRNA-mediated Inhibition of hTERT enhances the effects of Curcumin in promoting cell death in precursor-B acute lymphoblastic leukemia cells: an in Silico and in vitro study. Sci. Rep. 15 (1), 3083 (2025).","journal-title":"Sci. Rep."},{"issue":"4","key":"11532_CR33","doi-asserted-by":"publisher","first-page":"2796","DOI":"10.1007\/s10528-023-10565-9","volume":"62","author":"F Yari","year":"2024","unstructured":"Yari, F. et al. Differential expression of the hTERT gene in umbilical Cord-Derived mesenchymal stem cells cocultured with B cell precursor leukemia cell microparticles or CD41+\/CD61\u2009+\u2009Platelet microparticles. Biochem. Genet. 62 (4), 2796\u20132809 (2024).","journal-title":"Biochem. Genet."},{"issue":"1","key":"11532_CR34","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s11033-023-09087-9","volume":"51","author":"M Katoueezadeh","year":"2024","unstructured":"Katoueezadeh, M. et al. Combinatorial targeting of telomerase and DNA-PK induces synergistic apoptotic effects against Pre-B acute lymphoblastic leukemia cells. Mol. Biol. Rep. 51 (1), 163 (2024).","journal-title":"Mol. Biol. Rep."},{"issue":"1","key":"11532_CR35","doi-asserted-by":"publisher","first-page":"29897","DOI":"10.1038\/s41598-024-80596-8","volume":"14","author":"M Ahmadi","year":"2024","unstructured":"Ahmadi, M. et al. Magnetic and pH sensitive nanocomposite microspheres for controlled Temozolomide delivery in glioblastoma cells. Sci. Rep. 14 (1), 29897 (2024).","journal-title":"Sci. Rep."},{"issue":"7","key":"11532_CR36","doi-asserted-by":"publisher","first-page":"103792","DOI":"10.1016\/j.xphs.2025.103792","volume":"114","author":"MH Ashoub","year":"2025","unstructured":"Ashoub, M. H., Golestani, A., Amiri, M., Razavi, R. & Farsinejad, A. pH-sensitive sulfasalazine release from green-synthesized mesoporous Fe3O4@SiO2 nanocomposites using Opuntia ficus-indica extract. J. Pharm. Sci. 114 (7), 103792 (2025).","journal-title":"J. Pharm. Sci."},{"issue":"1","key":"11532_CR37","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1007\/s10971-023-06251-2","volume":"109","author":"M Taeby","year":"2024","unstructured":"Taeby, M., Ashoub, M. H., Asghari, M., Farsinejad, A. & Amiri, M. Sol\u2013gel synthesis of strontium ferrate (SrFeO3) nanoparticles and evaluation of anti-leukemic effects against leukemic cell lines. J. Solgel Sci. Technol. 109 (1), 56\u201365 (2024).","journal-title":"J. Solgel Sci. Technol."},{"key":"11532_CR38","doi-asserted-by":"publisher","first-page":"101479","DOI":"10.1016\/j.rineng.2023.101479","volume":"20","author":"MH Ashoub","year":"2023","unstructured":"Ashoub, M. H. et al. Induction of ferroptosis cell death in acute promyelocytic leukemia cell lines (NB4 and HL-60) using hydrothermally synthesized ZnO NPs in the presence of black cardamom extract. Results Eng. 20, 101479 (2023).","journal-title":"Results Eng."},{"issue":"1","key":"11532_CR39","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1039\/D2MA00647B","volume":"4","author":"B Dutta","year":"2023","unstructured":"Dutta, B. et al. Surface engineered Fe 3 O 4 nanomagnets for pH-responsive delivery of gemcitabine hydrochloride and in vivo tracking by radiolabeling. Mater. Adv. 4 (1), 195\u2013204 (2023).","journal-title":"Mater. Adv."},{"key":"11532_CR40","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.molcata.2014.10.019","volume":"396","author":"M Nasrollahzadeh","year":"2015","unstructured":"Nasrollahzadeh, M., Sajadi, S. M. & Maham, M. Green synthesis of palladium nanoparticles using Hippophae rhamnoides Linn leaf extract and their catalytic activity for the Suzuki\u2013Miyaura coupling in water. J. Mol. Catal. A: Chem. 396, 297\u2013303 (2015).","journal-title":"J. Mol. Catal. A: Chem."},{"issue":"04","key":"11532_CR41","doi-asserted-by":"publisher","first-page":"2450024","DOI":"10.1142\/S1793292024500243","volume":"19","author":"R Arora","year":"2024","unstructured":"Arora, R., Bharti, V. K. & Dey, S. Unlocking the potential of Trans-Himalayan High-Altitude Seabuckthorn (Hippophae rhamnoides) plants in the green synthesis of silver nanoparticles against Drug-Resistant foodborne pathogens: A step towards sustainable food safety goals. Nano 19 (04), 2450024 (2024).","journal-title":"Nano"},{"key":"11532_CR42","unstructured":"Dadhwal, P., Dhingra, H. K. & Dwivedi, V. Detection of antimicrobial properties of green synthesized copper nanoparticles using Hippophae rhamnoides L. Ann. Agri-Bio Res. (2023)."},{"issue":"sup2","key":"11532_CR43","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1080\/21691401.2018.1458034","volume":"46","author":"B Sharma","year":"2018","unstructured":"Sharma, B. & Deswal, R. Single pot synthesized gold nanoparticles using Hippophae rhamnoides leaf and berry extract showed shape-dependent differential Nanobiotechnological applications. Artif. Cells Nanomed. Biotechnol. 46 (sup2), 408\u2013418 (2018).","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"10","key":"11532_CR44","doi-asserted-by":"publisher","first-page":"3093","DOI":"10.1016\/j.apsusc.2009.11.079","volume":"256","author":"K Yang","year":"2010","unstructured":"Yang, K., Peng, H., Wen, Y. & Li, N. Re-examination of characteristic FTIR spectrum of secondary layer in bilayer oleic acid-coated Fe3O4 nanoparticles. Appl. Surf. Sci. 256 (10), 3093\u20133097 (2010).","journal-title":"Appl. Surf. Sci."},{"issue":"23","key":"11532_CR45","doi-asserted-by":"publisher","first-page":"20628","DOI":"10.1021\/acsami.9b03040","volume":"11","author":"MJ Uddin","year":"2019","unstructured":"Uddin, M. J., Abidi, N., Warzywoda, J. & Gill, H. S. Investigation of the fate of proteins and hydrophilicity\/hydrophobicity of Lycopodium clavatum spores after organic Solvent\u2013Base\u2013Acid treatment. ACS Appl. Mater. Interfaces. 11 (23), 20628\u201320641 (2019).","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"23","key":"11532_CR46","doi-asserted-by":"publisher","first-page":"13378","DOI":"10.1007\/s10853-017-1441-7","volume":"52","author":"MO Castro","year":"2017","unstructured":"Castro, M. O. et al. Hydrochar as protein support: preservation of biomolecule properties with non-covalent immobilization. J. Mater. Sci. 52 (23), 13378\u201313389 (2017).","journal-title":"J. Mater. Sci."},{"key":"11532_CR47","doi-asserted-by":"publisher","first-page":"S355","DOI":"10.1016\/S2152-2650(22)01493-8","volume":"22","author":"H Ababneh","year":"2022","unstructured":"Ababneh, H., Frigault, M. & Patel, C. ABCL-044 clinical outcomes of commercial CD19-Targeted CAR T-Cell therapy in patients with secondary central nervous system lymphoma. Clin. Lymphoma Myeloma Leuk. 22, S355 (2022).","journal-title":"Clin. Lymphoma Myeloma Leuk."},{"key":"11532_CR48","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.cattod.2017.12.028","volume":"313","author":"L Kemmou","year":"2018","unstructured":"Kemmou, L., Frontistis, Z., Vakros, J., Manariotis, I. D. & Mantzavinos, D. Degradation of antibiotic sulfamethoxazole by biochar-activated persulfate: factors affecting the activation and degradation processes. Catal. Today. 313, 128\u2013133 (2018).","journal-title":"Catal. Today"},{"key":"11532_CR49","doi-asserted-by":"crossref","unstructured":"Ali, A. et al. Synthesis, characterization, applications, and challenges of iron oxide nanoparticles. Nanatechnol. Sci. Appl. 9, 49\u201367 (2016).","DOI":"10.2147\/NSA.S99986"},{"issue":"1","key":"11532_CR50","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1166\/sl.2014.3224","volume":"12","author":"S Hwang","year":"2014","unstructured":"Hwang, S., Umar, A., Dar, G., Kim, S. & Badran, R. Synthesis and characterization of iron oxide nanoparticles for phenyl hydrazine sensor applications. Sens. Lett. 12 (1), 97\u2013101 (2014).","journal-title":"Sens. Lett."},{"issue":"3","key":"11532_CR51","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1016\/j.matchemphys.2011.08.027","volume":"130","author":"H-L Wang","year":"2011","unstructured":"Wang, H-L., Cui, J-Y. & Jiang, W-F. Synthesis, characterization and flocculation activity of novel Fe (OH) 3\u2013polyacrylamide hybrid polymer. Mater. Chem. Phys. 130 (3), 993\u2013999 (2011).","journal-title":"Mater. Chem. Phys."},{"issue":"12","key":"11532_CR52","first-page":"16786","volume":"32","author":"M Fuentes-P\u00e9rez","year":"2021","unstructured":"Fuentes-P\u00e9rez, M. et al. Synthesis and study of physicochemical properties of Fe3O4@ ZnFe2O4 core\/shell nanoparticles. J. Mater. Sci.: Mater. Electron. 32 (12), 16786\u201316799 (2021).","journal-title":"J. Mater. Sci.: Mater. Electron."},{"issue":"11","key":"11532_CR53","doi-asserted-by":"publisher","first-page":"6342","DOI":"10.1021\/la0636199","volume":"23","author":"J Zhang","year":"2007","unstructured":"Zhang, J., Srivastava, R. & Misra, R. Core\u2009\u2013\u2009shell magnetite nanoparticles surface encapsulated with smart stimuli-responsive polymer: synthesis, characterization, and LCST of viable drug-targeting delivery system. Langmuir 23 (11), 6342\u20136351 (2007).","journal-title":"Langmuir"},{"key":"11532_CR54","doi-asserted-by":"crossref","unstructured":"Husain, S. et al. (eds) Synthesis and characterization of Fe3O4 magnetic nanoparticles from iron ore. Journal of Physics: Conference Series; : IOP Publishing. (2019).","DOI":"10.1088\/1742-6596\/1242\/1\/012021"},{"issue":"13","key":"11532_CR55","doi-asserted-by":"publisher","first-page":"1828","DOI":"10.1016\/j.jmmm.2009.12.035","volume":"322","author":"W Lu","year":"2010","unstructured":"Lu, W., Shen, Y., Xie, A. & Zhang, W. Green synthesis and characterization of superparamagnetic Fe3O4 nanoparticles. J. Magn. Magn. Mater. 322 (13), 1828\u20131833 (2010).","journal-title":"J. Magn. Magn. Mater."},{"issue":"1","key":"11532_CR56","doi-asserted-by":"publisher","first-page":"21996","DOI":"10.1038\/s41598-021-01538-2","volume":"11","author":"TT Win","year":"2021","unstructured":"Win, T. T., Khan, S., Bo, B., Zada, S. & Fu, P. Green synthesis and characterization of Fe3O4 nanoparticles using Chlorella-K01 extract for potential enhancement of plant growth stimulating and antifungal activity. Sci. Rep. 11 (1), 21996 (2021).","journal-title":"Sci. Rep."},{"issue":"5","key":"11532_CR57","doi-asserted-by":"publisher","first-page":"5954","DOI":"10.3390\/molecules18055954","volume":"18","author":"M Mahdavi","year":"2013","unstructured":"Mahdavi, M., Namvar, F., Ahmad, M. B. & Mohamad, R. Green biosynthesis and characterization of magnetic iron oxide (Fe3O4) nanoparticles using seaweed (Sargassum muticum) aqueous extract. Molecules 18 (5), 5954\u20135964 (2013).","journal-title":"Molecules"},{"key":"11532_CR58","doi-asserted-by":"publisher","first-page":"1399937","DOI":"10.3389\/fmicb.2024.1399937","volume":"15","author":"N Rana","year":"2024","unstructured":"Rana, N. et al. Phytofabrication, characterization of silver nanoparticles using Hippophae rhamnoides berries extract and their biological activities. Front. Microbiol. 15, 1399937 (2024).","journal-title":"Front. Microbiol."},{"issue":"1","key":"11532_CR59","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.foodchem.2007.05.059","volume":"106","author":"O Ma\u00e2mouri","year":"2008","unstructured":"Ma\u00e2mouri, O. et al. Mid infrared attenuated total reflection spectroscopy as a rapid tool to assess the quality of Sicilo-Sarde ewe\u2019s milk during the lactation period after replacing soybean meal with scotch bean in the feed ration. Food Chem. 106 (1), 361\u2013368 (2008).","journal-title":"Food Chem."},{"issue":"4","key":"11532_CR60","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1002\/1097-0282(2000)57:4<257::AID-BIP7>3.0.CO;2-3","volume":"57","author":"NA Nikonenko","year":"2000","unstructured":"Nikonenko, N. A., Buslov, D. K., Sushko, N. I. & Zhbankov, R. G. Investigation of stretching vibrations of glycosidic linkages in disaccharides and polysaccharides with use of IR spectra Deconvolution. Biopolymers 57 (4), 257\u2013262 (2000).","journal-title":"Biopolymers"},{"issue":"7","key":"11532_CR61","doi-asserted-by":"publisher","first-page":"375","DOI":"10.5897\/AJPP12.1246","volume":"7","author":"B Ahmad","year":"2013","unstructured":"Ahmad, B. & Ali, J. Physiochemical, minerals, phytochemical contents, antimicrobial activities evaluation and fourier transform infrared (FTIR) analysis of Hippophae rhamnoides L. leaves extracts. Afr. J. Pharm. Pharmacol. 7 (7), 375\u2013388 (2013).","journal-title":"Afr. J. Pharm. Pharmacol."},{"issue":"4","key":"11532_CR62","first-page":"607","volume":"15","author":"DD Gore","year":"2023","unstructured":"Gore, D. D. et al. Comparative quantitative analysis of fruit oil from Hippophae rhamnoides (seabuckthorn) by qNMR, FTIR and GC\u2013MS. Chin. Herb. Med. 15 (4), 607\u2013613 (2023).","journal-title":"Chin. Herb. Med."},{"key":"11532_CR63","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1007\/s10973-016-5393-y","volume":"125","author":"M Stoia","year":"2016","unstructured":"Stoia, M., Istratie, R. & P\u0103curariu, C. Investigation of magnetite nanoparticles stability in air by thermal analysis and FTIR spectroscopy. J. Therm. Anal. Calorim. 125, 1185\u20131198 (2016).","journal-title":"J. Therm. Anal. Calorim."},{"key":"11532_CR64","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s13538-024-01589-6","volume":"54","author":"TS Morphological","year":"2024","unstructured":"Morphological, T. S. Investigation of inverse spinel (Magnetite\u2013Fe. Braz. J. Phys. 54, 244 (2024).","journal-title":"Braz. J. Phys."},{"key":"11532_CR65","doi-asserted-by":"crossref","unstructured":"Sparavigna, A. C. Raman Spectroscopy of the Iron Oxides in the Form of Minerals, Particles and Nanoparticles. (2023).","DOI":"10.26434\/chemrxiv-2023-22kh4"},{"key":"11532_CR66","doi-asserted-by":"publisher","first-page":"2199","DOI":"10.1007\/s10948-020-05481-7","volume":"33","author":"BS Yadav","year":"2020","unstructured":"Yadav, B. S., Singh, R., Vishwakarma, A. K. & Kumar, N. Facile synthesis of substantially magnetic Hollow nanospheres of maghemite (\u03b3-Fe 2 O 3) originated from magnetite (Fe 3 O 4) via solvothermal method. J. Supercond. Novel Magn. 33, 2199\u20132208 (2020).","journal-title":"J. Supercond. Novel Magn."},{"key":"11532_CR67","doi-asserted-by":"crossref","unstructured":"Yusefi, M. et al. Green synthesis of Fe3O4 nanoparticles stabilized by a Garcinia mangostana fruit Peel extract for hyperthermia and anticancer activities. Int. J. Nanomed. 16, 2515\u20132532. (2021).","DOI":"10.2147\/IJN.S284134"},{"key":"11532_CR68","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s10876-016-1082-z","volume":"28","author":"P Nagajyothi","year":"2017","unstructured":"Nagajyothi, P., Pandurangan, M., Kim, D. H., Sreekanth, T. & Shim, J. Green synthesis of iron oxide nanoparticles and their catalytic and in vitro anticancer activities. J. Cluster Sci. 28, 245\u2013257 (2017).","journal-title":"J. Cluster Sci."},{"key":"11532_CR69","doi-asserted-by":"crossref","unstructured":"Chokkareddy, R. & Redhi, G. G. Green synthesis of metal nanoparticles and its reaction mechanisms. Green metal nanoparticles: synthesis, characterization and their applications. :113\u2009\u2013\u200939. (2018).","DOI":"10.1002\/9781119418900.ch4"},{"key":"11532_CR70","doi-asserted-by":"publisher","first-page":"129198","DOI":"10.1016\/j.jclepro.2021.129198","volume":"324","author":"JA Kumar","year":"2021","unstructured":"Kumar, J. A. et al. A focus to green synthesis of metal\/metal based oxide nanoparticles: various mechanisms and applications towards ecological approach. J. Clean. Prod. 324, 129198 (2021).","journal-title":"J. Clean. Prod."},{"key":"11532_CR71","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.physb.2014.04.031","volume":"449","author":"S Venkateswarlu","year":"2014","unstructured":"Venkateswarlu, S., Kumar, B. N., Prasad, C., Venkateswarlu, P. & Jyothi, N. Bio-inspired green synthesis of Fe3O4 spherical magnetic nanoparticles using Syzygium cumini seed extract. Phys. B: Condens. Matter. 449, 67\u201371 (2014).","journal-title":"Phys. B: Condens. Matter"},{"key":"11532_CR72","doi-asserted-by":"crossref","unstructured":"Tabassum, R. & Dilshad, E. A comparative anticancer analysis of iron oxide nanoparticles of Hippophae rhamnoides and Cichorium intybus found in the Karakoram range of Gilgit Baltistan against liver cancer targeting the RhoA gene. Drug Dev. Ind. Pharm. 1\u201310. (2024).","DOI":"10.1080\/03639045.2024.2400209"},{"issue":"7","key":"11532_CR73","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.arabjc.2017.05.011","volume":"12","author":"I Khan","year":"2019","unstructured":"Khan, I., Saeed, K., Khan, I. & Nanoparticles Properties, applications and toxicities. Arab. J. Chem. 12 (7), 908\u2013931 (2019).","journal-title":"Arab. J. Chem."},{"key":"11532_CR74","doi-asserted-by":"publisher","first-page":"1155622","DOI":"10.3389\/fmicb.2023.1155622","volume":"14","author":"KA Altammar","year":"2023","unstructured":"Altammar, K. A. A review on nanoparticles: characteristics, synthesis, applications, and challenges. Front. Microbiol. 14, 1155622 (2023).","journal-title":"Front. Microbiol."},{"issue":"18","key":"11532_CR75","doi-asserted-by":"publisher","first-page":"2665","DOI":"10.3390\/w16182665","volume":"16","author":"H Sun","year":"2024","unstructured":"Sun, H., Liu, Y., Zhou, Y., Chen, Z. & Li, J. Green synthesis of Iron-Based nanoparticles using pomegranate leaf extracts: characterization, biomolecules and Indole removal. Water 16 (18), 2665 (2024).","journal-title":"Water"},{"issue":"6","key":"11532_CR76","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1002\/nano.202000162","volume":"2","author":"MI Anik","year":"2021","unstructured":"Anik, M. I. et al. Recent progress of magnetic nanoparticles in biomedical applications: A review. Nano Select. 2 (6), 1146\u20131186 (2021).","journal-title":"Nano Select"},{"issue":"4","key":"11532_CR77","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.3390\/molecules26041077","volume":"26","author":"M Mabrouk","year":"2021","unstructured":"Mabrouk, M., Das, D. B., Salem, Z. A. & Beherei, H. H. Nanomaterials for biomedical applications: production, characterisations, recent trends and difficulties. Molecules 26 (4), 1077 (2021).","journal-title":"Molecules"},{"key":"11532_CR78","first-page":"100500","volume":"24","author":"A Hosseingholian","year":"2023","unstructured":"Hosseingholian, A. et al. Recent advances in green synthesized nanoparticles: from production to application. Mater. Today Sustain. 24, 100500 (2023).","journal-title":"Mater. Today Sustain."},{"issue":"19","key":"11532_CR79","doi-asserted-by":"publisher","first-page":"6472","DOI":"10.3390\/molecules27196472","volume":"27","author":"BA Miu","year":"2022","unstructured":"Miu, B. A. & Dinischiotu, A. New green approaches in nanoparticles synthesis: an overview. Molecules 27 (19), 6472 (2022).","journal-title":"Molecules"},{"issue":"2","key":"11532_CR80","doi-asserted-by":"publisher","first-page":"e756","DOI":"10.1016\/j.jmmm.2007.03.085","volume":"316","author":"P Guardia","year":"2007","unstructured":"Guardia, P. et al. Surfactant effects in magnetite nanoparticles of controlled size. J. Magn. Magn. Mater. 316 (2), e756\u2013e9 (2007).","journal-title":"J. Magn. Magn. Mater."},{"issue":"11","key":"11532_CR81","doi-asserted-by":"publisher","first-page":"601","DOI":"10.3390\/pharmaceutics11110601","volume":"11","author":"J Wallyn","year":"2019","unstructured":"Wallyn, J., Anton, N. & Vandamme, T. F. Synthesis, principles, and properties of magnetite nanoparticles for in vivo imaging applications\u2014A review. Pharmaceutics 11 (11), 601 (2019).","journal-title":"Pharmaceutics"},{"key":"11532_CR82","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.jallcom.2018.06.246","volume":"766","author":"P Ar\u00e9valo-Cid","year":"2018","unstructured":"Ar\u00e9valo-Cid, P., Isasi, J. & Mart\u00edn-Hern\u00e1ndez, F. Comparative study of core-shell nanostructures based on amino-functionalized Fe3O4@ SiO2 and CoFe2O4@ SiO2 nanocomposites. J. Alloys Compd. 766, 609\u2013618 (2018).","journal-title":"J. Alloys Compd."},{"issue":"11","key":"11532_CR83","doi-asserted-by":"publisher","first-page":"2178","DOI":"10.3390\/nano10112178","volume":"10","author":"T Krasia-Christoforou","year":"2020","unstructured":"Krasia-Christoforou, T. et al. From single-core nanoparticles in ferrofluids to multi-core magnetic nanocomposites: assembly strategies, structure, and magnetic behavior. Nanomaterials 10 (11), 2178 (2020).","journal-title":"Nanomaterials"},{"key":"11532_CR84","doi-asserted-by":"publisher","first-page":"102810","DOI":"10.1016\/j.cis.2022.102810","volume":"311","author":"J Philip","year":"2023","unstructured":"Philip, J. Magnetic nanofluids (Ferrofluids): recent advances, applications, challenges, and future directions. Adv. Colloid Interface Sci. 311, 102810 (2023).","journal-title":"Adv. Colloid Interface Sci."},{"issue":"3","key":"11532_CR85","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1039\/C9TB01955C","volume":"8","author":"Y Xiao","year":"2020","unstructured":"Xiao, Y. & Du, J. Superparamagnetic nanoparticles for biomedical applications. J. Mater. Chem. B. 8 (3), 354\u2013367 (2020).","journal-title":"J. Mater. Chem. B"},{"issue":"5","key":"11532_CR86","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1002\/jbm.a.35654","volume":"104","author":"X Li","year":"2016","unstructured":"Li, X. et al. Current investigations into magnetic nanoparticles for biomedical applications. J. Biomedical Mater. Res. Part. A. 104 (5), 1285\u20131296 (2016).","journal-title":"J. Biomedical Mater. Res. Part. A"},{"issue":"15","key":"11532_CR87","doi-asserted-by":"publisher","first-page":"6750","DOI":"10.3390\/app14156750","volume":"14","author":"SY Ru\u00edz-Baltazar \u00c1dJ, Reyes-L\u00f3pez","year":"2024","unstructured":"Ru\u00edz-Baltazar \u00c1dJ, Reyes-L\u00f3pez, S. Y., M\u00e9ndez-Lozano, N. & Ju\u00e1rez-Moreno, K. Evaluation of superparamagnetic Fe3O4-Ag decorated nanoparticles: cytotoxicity studies in human fibroblasts (HFF-1) and breast Cancer cells (MCF-7). Appl. Sci. 14 (15), 6750 (2024).","journal-title":"Appl. Sci."},{"key":"11532_CR88","doi-asserted-by":"crossref","unstructured":"Devi, Y. L., Thongam, B. & Devi, R. J. Amaranthus and Sea Buckthorn: Future Smart Crops for Cancer Therapyp. 77\u201393 (CRC, 2025).","DOI":"10.1201\/9781003477792-6"},{"issue":"1","key":"11532_CR89","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s44371-025-00091-5","volume":"2","author":"R Soomro","year":"2025","unstructured":"Soomro, R., Abdelmonem, M., Meli, A. D., Panhwar, M. & Che Abdullah, C. A. A novel plant-based approach for synthesis of iron oxide nanoparticles and cancer therapy. Discover Chem. 2 (1), 25 (2025).","journal-title":"Discover Chem."},{"issue":"1","key":"11532_CR90","doi-asserted-by":"publisher","first-page":"19000","DOI":"10.1038\/s41598-023-46287-6","volume":"13","author":"BA Eldeeb","year":"2023","unstructured":"Eldeeb, B. A., El-Raheem, W. M. A. & Elbeltagi, S. Green synthesis of biocompatible Fe3O4 magnetic nanoparticles using Citrus Sinensis peels extract for their biological activities and magnetic-hyperthermia applications. Sci. Rep. 13 (1), 19000 (2023).","journal-title":"Sci. Rep."},{"issue":"1","key":"11532_CR91","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12645-024-00248-4","volume":"15","author":"H Xiong","year":"2024","unstructured":"Xiong, H. et al. Investigation of mitochondria-dependent apoptosis pathway and lipid peroxidation level induced by biosynthesized silver nanoparticles: caspase-3 activation, BAK1\/BCLx regulation and malondialdehyde production. Cancer Nanotechnol. 15 (1), 13 (2024).","journal-title":"Cancer Nanotechnol."},{"issue":"37","key":"11532_CR92","doi-asserted-by":"publisher","first-page":"6681","DOI":"10.2174\/1381612811319370011","volume":"19","author":"M Ahamed","year":"2013","unstructured":"Ahamed, M. et al. Iron oxide nanoparticle-induced oxidative stress and genotoxicity in human skin epithelial and lung epithelial cell lines. Curr. Pharm. Des. 19 (37), 6681\u20136690 (2013).","journal-title":"Curr. Pharm. Des."},{"key":"11532_CR93","doi-asserted-by":"publisher","first-page":"5080843","DOI":"10.1155\/2019\/5080843","volume":"2019","author":"LJ Su","year":"2019","unstructured":"Su, L. J. et al. Reactive oxygen Species-Induced lipid peroxidation in apoptosis, autophagy, and ferroptosis. Oxid. Med. Cell. Longev. 2019, 5080843 (2019).","journal-title":"Oxid. Med. Cell. Longev."},{"key":"11532_CR94","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.physb.2014.04.031","volume":"449","author":"S Venkateswarlu","year":"2014","unstructured":"Venkateswarlu, S., Natesh Kumar, B., Prasad, C. H., Venkateswarlu, P. & Jyothi, N. V. V. Bio-inspired green synthesis of Fe3O4 spherical magnetic nanoparticles using Syzygium cumini seed extract. Phys. B: Condens. Matter. 449, 67\u201371 (2014).","journal-title":"Phys. B: Condens. Matter"},{"issue":"4","key":"11532_CR95","doi-asserted-by":"publisher","first-page":"101505","DOI":"10.1016\/j.jscs.2022.101505","volume":"26","author":"T Huang","year":"2022","unstructured":"Huang, T. et al. Green synthesis of Ag\/Fe3O4 nanoparticles using Mentha extract: preparation, characterization and investigation of its anti-human lung cancer application. J. Saudi Chem. Soc. 26 (4), 101505 (2022).","journal-title":"J. Saudi Chem. Soc."},{"key":"11532_CR96","doi-asserted-by":"publisher","first-page":"103560","DOI":"10.1016\/j.algal.2024.103560","volume":"80","author":"N Jafari","year":"2024","unstructured":"Jafari, N., Hamishehkar, H. & Mohammadpourfard, M. Dunaliella salina microalgae aqueous extract-based magnetic nanoparticles (Fe3O4-NPs): green synthesis, characterization and in vitro anticancer investigations. Algal Res. 80, 103560 (2024).","journal-title":"Algal Res."},{"key":"11532_CR97","doi-asserted-by":"crossref","unstructured":"Arfin, S. et al. Oxidative stress in Cancer cell metabolism. Antioxid. (Basel) ;10(5), 642 (2021).","DOI":"10.3390\/antiox10050642"},{"issue":"29","key":"11532_CR98","doi-asserted-by":"publisher","first-page":"2401197","DOI":"10.1002\/adhm.202401197","volume":"13","author":"J Farheen","year":"2024","unstructured":"Farheen, J., Iqbal, M. Z., Mushtaq, A., Hou, Y. & Kong, X. Hippophae Rhamnoides-derived phytomedicine Nano\u2010System modulates bax\/fas pathways to reduce proliferation in Triple\u2010Negative breast Cancer. Adv. Healthc. Mater. 13 (29), 2401197 (2024).","journal-title":"Adv. Healthc. Mater."},{"issue":"5","key":"11532_CR99","doi-asserted-by":"publisher","first-page":"406","DOI":"10.7555\/JBR.28.20130110","volume":"28","author":"T Usha","year":"2014","unstructured":"Usha, T. et al. Molecular Docking studies of anti-cancerous candidates in Hippophae rhamnoides and Hippophae salicifolia. J. Biomedical Res. 28 (5), 406 (2014).","journal-title":"J. Biomedical Res."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11532-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11532-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11532-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T12:41:23Z","timestamp":1757248883000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-11532-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,16]]},"references-count":99,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["11532"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-11532-7","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,16]]},"assertion":[{"value":"14 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study gained the approval of the ethical committee of the Kerman University of Medical Sciences. All methods were performed in accordance with the relevant guidelines and regulations.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}],"article-number":"25743"}}