{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T12:07:52Z","timestamp":1768824472209,"version":"3.49.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100008762","name":"Genome Canada","doi-asserted-by":"publisher","award":["13529"],"award-info":[{"award-number":["13529"]}],"id":[{"id":"10.13039\/100008762","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","award":["155865"],"award-info":[{"award-number":["155865"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Fonds de recherche du Qu\u00e9bec (FRQ)-Secteur Sant\u00e9"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-13641-9","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:15:23Z","timestamp":1753877723000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Structural equation modeling of factors influencing women\u2019s attitudes, comfort and willingness toward risk-stratified breast cancer screening"],"prefix":"10.1038","volume":"15","author":[{"given":"Cynthia","family":"Mbuya-Bienge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nora","family":"Pashayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Simard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Nabi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,30]]},"reference":[{"key":"13641_CR1","unstructured":"Canadian Cancer Society\/Soci\u00e9t\u00e9 canadienne du. Breast Cancer Statistics. https:\/\/cancer.ca\/en\/cancer-information\/cancer-types\/breast\/statistics (Canadian Cancer Society, 2023)."},{"key":"13641_CR2","doi-asserted-by":"publisher","first-page":"084653712412464","DOI":"10.1177\/08465371241246422","volume":"1","author":"JM Seely","year":"2024","unstructured":"Seely, J. M., Ellison, L. F., Billette, J.-M., Zhang, S. X. & Wilkinson, A. N. Incidence of breast cancer in younger women: A Canadian trend analysis. Can. Assoc. Radiol. J. 1, 08465371241246422. https:\/\/doi.org\/10.1177\/08465371241246422 (2024).","journal-title":"Can. Assoc. Radiol. J."},{"key":"13641_CR3","unstructured":"Canadian Partnership Against Cancer. Breast Cancer Screening in Canada: Environmental Scan (2019\u20132020) 78. https:\/\/www.partnershipagainstcancer.ca\/topics\/breast-cancer-screening-scan-2019-2020\/ (2021)."},{"key":"13641_CR4","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/s41416-021-01550-3","volume":"126","author":"AK Clift","year":"2022","unstructured":"Clift, A. K. et al. The current status of risk-stratified breast screening. Br. J. Cancer 126, 533\u2013550 (2022).","journal-title":"Br. J. Cancer"},{"key":"13641_CR5","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.1016\/S0140-6736(12)61611-0","volume":"380","author":"Independent UK Panel on Breast Cancer Screening","year":"2012","unstructured":"Independent UK Panel on Breast Cancer Screening. The benefits and harms of breast cancer screening: an independent review. The Lancet 380, 1778\u20131786 (2012).","journal-title":"The Lancet"},{"key":"13641_CR6","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1038\/bjc.2013.177","volume":"108","author":"MG Marmot","year":"2013","unstructured":"Marmot, M. G. et al. The benefits and harms of breast cancer screening: An independent review. Br. J. Cancer 108, 2205\u20132240 (2013).","journal-title":"Br. J. Cancer"},{"key":"13641_CR7","doi-asserted-by":"publisher","first-page":"4287","DOI":"10.3390\/cancers13174287","volume":"13","author":"S \u0141ukasiewicz","year":"2021","unstructured":"\u0141ukasiewicz, S. et al. Breast cancer\u2014Epidemiology, risk factors, classification, prognostic markers, and current treatment strategies\u2014An updated review. Cancers 13, 4287 (2021).","journal-title":"Cancers"},{"key":"13641_CR8","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1093\/pubmed\/fdt078","volume":"36","author":"AE Hall","year":"2014","unstructured":"Hall, A. E. et al. Implementing risk-stratified screening for common cancers: A review of potential ethical, legal and social issues. J. Public Health 36, 285\u2013291 (2014).","journal-title":"J. Public Health"},{"key":"13641_CR9","doi-asserted-by":"publisher","first-page":"511","DOI":"10.3390\/jpm11060511","volume":"11","author":"JD Brooks","year":"2021","unstructured":"Brooks, J. D. et al. Personalized risk assessment for prevention and early detection of breast cancer: Integration and implementation (PERSPECTIVE I&I). J. Pers. Med. 11, 511 (2021).","journal-title":"J. Pers. Med."},{"key":"13641_CR10","doi-asserted-by":"publisher","first-page":"2116","DOI":"10.3390\/cancers16112116","volume":"16","author":"MJ Walker","year":"2024","unstructured":"Walker, M. J. et al. Implementing multifactorial risk assessment with polygenic risk scores for personalized breast cancer screening in the population setting: Challenges and opportunities. Cancers 16, 2116 (2024).","journal-title":"Cancers"},{"key":"13641_CR11","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1038\/s41571-020-0388-9","volume":"17","author":"N Pashayan","year":"2020","unstructured":"Pashayan, N. et al. Personalized early detection and prevention of breast cancer: ENVISION consensus statement. Nat. Rev. Clin. Oncol. 17, 687\u2013705 (2020).","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"13641_CR12","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/s12913-017-2031-8","volume":"17","author":"M Sekhon","year":"2017","unstructured":"Sekhon, M., Cartwright, M. & Francis, J. J. Acceptability of healthcare interventions: An overview of reviews and development of a theoretical framework. BMC Health Serv. Res. 17, 88 (2017).","journal-title":"BMC Health Serv. Res."},{"key":"13641_CR13","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1038\/s41416-023-02268-0","volume":"129","author":"L McWilliams","year":"2023","unstructured":"McWilliams, L. et al. What do women think about having received their breast cancer risk as part of a risk-stratified NHS Breast Screening Programme? A qualitative study. Br. J. Cancer 129, 356\u2013365 (2023).","journal-title":"Br. J. Cancer"},{"key":"13641_CR14","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1177\/0969141319877669","volume":"27","author":"A Ghanouni","year":"2020","unstructured":"Ghanouni, A., Waller, J., Stoffel, S. T., Vlaev, I. & von Wagner, C. Acceptability of risk-stratified breast screening: Effect of the order of presenting risk and benefit information. J. Med. Screen. 27, 52\u201356 (2020).","journal-title":"J. Med. Screen."},{"key":"13641_CR15","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1186\/s12885-020-07464-2","volume":"20","author":"L Rainey","year":"2020","unstructured":"Rainey, L., van der Waal, D. & Broeders, M. J. M. Dutch women\u2019s intended participation in a risk-based breast cancer screening and prevention programme: A survey study identifying preferences, facilitators and barriers. BMC Cancer 20, 965 (2020).","journal-title":"BMC Cancer"},{"key":"13641_CR16","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3390\/jpm11020095","volume":"11","author":"C Mbuya Bienge","year":"2021","unstructured":"Mbuya Bienge, C. et al. Women\u2019s views on multifactorial breast cancer risk assessment and risk-stratified screening: A population-based survey from four provinces in Canada. J. Pers. Med. 11, 95 (2021).","journal-title":"J. Pers. Med."},{"key":"13641_CR17","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1186\/s12885-024-12083-2","volume":"24","author":"LH Loft","year":"2024","unstructured":"Loft, L. H., Pedersen, L. H., Bigaard, J. & Bojesen, S. E. Attitudes towards risk-stratified breast cancer screening: A population-based survey among 5,001 Danish women. BMC Cancer 24, 347 (2024).","journal-title":"BMC Cancer"},{"key":"13641_CR18","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1186\/1756-0500-3-267","volume":"3","author":"TN Beran","year":"2010","unstructured":"Beran, T. N. & Violato, C. Structural equation modeling in medical research: A primer. BMC Res. Notes 3, 267 (2010).","journal-title":"BMC Res. Notes"},{"key":"13641_CR19","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1093\/aje\/kws213","volume":"176","author":"TJ VanderWeele","year":"2012","unstructured":"VanderWeele, T. J. Invited commentary: Structural equation models and epidemiologic analysis. Am. J. Epidemiol. 176, 608\u2013612 (2012).","journal-title":"Am. J. Epidemiol."},{"key":"13641_CR20","volume-title":"Structural Equation Modeling: Applications Using Mplus","author":"J Wang","year":"2020","unstructured":"Wang, J. & Wang, X. Structural Equation Modeling: Applications Using Mplus 2nd edn. (Wiley, 2020).","edition":"2"},{"key":"13641_CR21","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1007\/s10490-023-09871-y","volume":"41","author":"GW Cheung","year":"2024","unstructured":"Cheung, G. W., Cooper-Thomas, H. D., Lau, R. S. & Wang, L. C. Reporting reliability, convergent and discriminant validity with structural equation modeling: A review and best-practice recommendations. Asia Pac. J. Manag. 41, 745\u2013783 (2024).","journal-title":"Asia Pac. J. Manag."},{"key":"13641_CR22","doi-asserted-by":"publisher","first-page":"53","DOI":"10.5116\/ijme.4dfb.8dfd","volume":"2","author":"M Tavakol","year":"2011","unstructured":"Tavakol, M. & Dennick, R. Making sense of Cronbach\u2019s alpha. Int. J. Med. Educ. 2, 53\u201355 (2011).","journal-title":"Int. J. Med. Educ."},{"key":"13641_CR23","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1080\/01490400.2015.1127189","volume":"39","author":"JJ Vaske","year":"2017","unstructured":"Vaske, J. J., Beaman, J. & Sponarski, C. C. Rethinking internal consistency in Cronbach\u2019s alpha. Leis. Sci. 39, 163\u2013173 (2017).","journal-title":"Leis. Sci."},{"key":"13641_CR24","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1080\/10705519909540135","volume":"6","author":"T Raykov","year":"1999","unstructured":"Raykov, T. & Marcoulides, G. A. On desirability of parsimony in structural equation model selection. Struct. Equ. Model. 6, 292\u2013300 (1999).","journal-title":"Struct. Equ. Model."},{"key":"13641_CR25","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.sapharm.2007.04.003","volume":"4","author":"JB Schreiber","year":"2008","unstructured":"Schreiber, J. B. Core reporting practices in structural equation modeling. Res. Social Adm. Pharm. 4, 83\u201397 (2008).","journal-title":"Res. Social Adm. Pharm."},{"key":"13641_CR26","first-page":"1","volume":"1","author":"C DiStefano","year":"2018","unstructured":"DiStefano, C., Liu, J., Jiang, N. & Shi, D. Examination of the weighted root mean square residual: Evidence for trustworthiness? Struct. Equ. Model. 1, 1 (2018).","journal-title":"Struct. Equ. Model."},{"key":"13641_CR27","doi-asserted-by":"publisher","first-page":"936","DOI":"10.3758\/s13428-015-0619-7","volume":"48","author":"C-H Li","year":"2016","unstructured":"Li, C.-H. Confirmatory factor analysis with ordinal data: Comparing robust maximum likelihood and diagonally weighted least squares. Behav. Res. 48, 936\u2013949 (2016).","journal-title":"Behav. Res."},{"key":"13641_CR28","doi-asserted-by":"publisher","first-page":"402","DOI":"10.4097\/kjae.2013.64.5.402","volume":"64","author":"H Kang","year":"2013","unstructured":"Kang, H. The prevention and handling of the missing data. Korean J. Anesthesiol. 64, 402\u2013406 (2013).","journal-title":"Korean J. Anesthesiol."},{"key":"13641_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12913-022-07577-3","volume":"22","author":"M Sekhon","year":"2022","unstructured":"Sekhon, M., Cartwright, M. & Francis, J. J. Development of a theory-informed questionnaire to assess the acceptability of healthcare interventions. BMC Health Serv. Res. 22, 1\u201312 (2022).","journal-title":"BMC Health Serv. Res."},{"key":"13641_CR30","unstructured":"Alyafei, A. & Easton-Carr, R. The health belief model of behavior change. In StatPearls (StatPearls Publishing, 2025)."},{"key":"13641_CR31","unstructured":"Government of Canada, S. C. Perceived Health, by Age Group. https:\/\/www150.statcan.gc.ca\/t1\/tbl1\/en\/tv.action?pid=1310009602 (2023)."},{"key":"13641_CR32","first-page":"122","volume":"1","author":"ETM de Jonge","year":"2009","unstructured":"de Jonge, E. T. M., Vlasselaer, J., Van de Putte, G. & Schobbens, J.-C. The construct of breast cancer risk perception: Need for a better risk communication? Facts Views Vis. Obgyn. 1, 122\u2013129 (2009).","journal-title":"Facts Views Vis. Obgyn."},{"key":"13641_CR33","first-page":"e300","volume":"63","author":"KD Volesky","year":"2017","unstructured":"Volesky, K. D. & Villeneuve, P. J. Examining screening mammography participation among women aged 40 to 74. Can. Fam. Phys. 63, e300\u2013e309 (2017).","journal-title":"Can. Fam. Phys."},{"key":"13641_CR34","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3747\/co.v16i5.359","volume":"16","author":"K Hanson","year":"2009","unstructured":"Hanson, K., Montgomery, P., Bakker, D. & Conlon, M. Factors influencing mammography participation in Canada: An integrative review of the literature. Curr. Oncol. 16, 65\u201375 (2009).","journal-title":"Curr. Oncol."},{"key":"13641_CR35","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/j.jacr.2019.02.044","volume":"16","author":"N Zha","year":"2019","unstructured":"Zha, N., Alabousi, M., Patel, B. K. & Patlas, M. N. Beyond universal health care: Barriers to breast cancer screening participation in Canada. J. Am. Coll. Radiol. 16, 570\u2013579 (2019).","journal-title":"J. Am. Coll. Radiol."},{"key":"13641_CR36","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1177\/08465371221147307","volume":"74","author":"DJ Cao","year":"2023","unstructured":"Cao, D. J., Alabousi, M., Farshait, N. & Patlas, M. N. Barriers to screening at-risk populations in Canada. Can. Assoc. Radiol. J. 74, 508\u2013513 (2023).","journal-title":"Can. Assoc. Radiol. J."},{"key":"13641_CR37","doi-asserted-by":"publisher","first-page":"7263","DOI":"10.3390\/curroncol30080527","volume":"30","author":"EB Jackson","year":"2023","unstructured":"Jackson, E. B., Simmons, C. E. & Chia, S. K. Current challenges and disparities in the delivery of equitable breast cancer care in Canada. Curr. Oncol. 30, 7263\u20137274 (2023).","journal-title":"Curr. Oncol."},{"key":"13641_CR38","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.breast.2015.02.001","volume":"24","author":"SF Meisel","year":"2015","unstructured":"Meisel, S. F. et al. Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK. Breast 24, 237\u2013241 (2015).","journal-title":"Breast"},{"key":"13641_CR39","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1177\/0969141319883662","volume":"27","author":"A Ghanouni","year":"2020","unstructured":"Ghanouni, A. et al. Attitudes towards risk-stratified breast cancer screening among women in England: A cross-sectional survey. J. Med. Screen. 27, 138\u2013145 (2020).","journal-title":"J. Med. Screen."},{"key":"13641_CR40","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3109\/0284186X.2015.1043024","volume":"55","author":"M Koitsalu","year":"2016","unstructured":"Koitsalu, M. et al. Public interest in and acceptability of the prospect of risk-stratified screening for breast and prostate cancer. Acta Oncol. 55, 45\u201351 (2016).","journal-title":"Acta Oncol."},{"key":"13641_CR41","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/2008-7802.104850","volume":"3","author":"AA Haghdoost","year":"2012","unstructured":"Haghdoost, A. A. Complexity of the socioeconomic status and its disparity as a determinant of health. Int. J. Prev. Med. 3, 75\u201376 (2012).","journal-title":"Int. J. Prev. Med."},{"key":"13641_CR42","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1186\/s12885-022-09484-6","volume":"22","author":"A Roux","year":"2022","unstructured":"Roux, A. et al. Study protocol comparing the ethical, psychological and socio-economic impact of personalised breast cancer screening to that of standard screening in the \u2018My Personal Breast Screening\u2019 (MyPeBS) randomised clinical trial. BMC Cancer 22, 507 (2022).","journal-title":"BMC Cancer"},{"key":"13641_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41523-017-0035-5","volume":"3","author":"LJ Esserman","year":"2017","unstructured":"Esserman, L. J. The WISDOM study: Breaking the deadlock in the breast cancer screening debate. NPJ Breast Cancer 3, 1\u20137 (2017).","journal-title":"NPJ Breast Cancer"},{"key":"13641_CR44","doi-asserted-by":"crossref","unstructured":"Evans, D. G. et al. PROCAS: Predicting risk of breast cancer at screening. In Improvement in Risk Prediction, Early Detection and Prevention of Breast Cancer in the NHS Breast Screening Programme and Family History Clinics: A Dual Cohort Study (NIHR Journals Library, 2016).","DOI":"10.3310\/pgfar04110"},{"key":"13641_CR45","doi-asserted-by":"publisher","first-page":"5380","DOI":"10.3390\/cancers15225380","volume":"15","author":"C Mbuya-Bienge","year":"2023","unstructured":"Mbuya-Bienge, C. et al. A systematic review and critical assessment of breast cancer risk prediction tools incorporating a polygenic risk score for the general population. Cancers 15, 5380 (2023).","journal-title":"Cancers"},{"key":"13641_CR46","doi-asserted-by":"publisher","first-page":"3189","DOI":"10.3390\/cancers16183189","volume":"16","author":"S-J Seung","year":"2024","unstructured":"Seung, S.-J. et al. Evaluating real world health system resource utilization and costs for a risk-based breast cancer screening approach in the Canadian PERSPECTIVE integration and implementation project. Cancers 16, 3189 (2024).","journal-title":"Cancers"},{"key":"13641_CR47","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.3390\/jpm13071027","volume":"13","author":"J Lapointe","year":"2023","unstructured":"Lapointe, J. et al. Canadian healthcare professionals\u2019 views and attitudes toward risk-stratified breast cancer screening. J. Person. Med. 13, 1027 (2023).","journal-title":"J. Person. Med."},{"key":"13641_CR48","doi-asserted-by":"publisher","first-page":"2380","DOI":"10.1016\/j.gim.2022.08.001","volume":"24","author":"J Lapointe","year":"2022","unstructured":"Lapointe, J. et al. Polygenic risk scores and risk-stratified breast cancer screening: Familiarity and perspectives of health care professionals. Genet. Med. 24, 2380\u20132388 (2022).","journal-title":"Genet. Med."},{"key":"13641_CR49","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1080\/10705511.2014.938596","volume":"22","author":"WE Bonifay","year":"2015","unstructured":"Bonifay, W. E., Reise, S. P., Scheines, R. & Meijer, R. R. When are multidimensional data unidimensional enough for structural equation modeling? An evaluation of the DETECT multidimensionality index. Struct. Equ. Model. 22, 504\u2013516 (2015).","journal-title":"Struct. Equ. Model."},{"key":"13641_CR50","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1080\/10705511.2019.1706527","volume":"27","author":"J Koran","year":"2020","unstructured":"Koran, J. Indicators per factor in confirmatory factor analysis: More is not always better. Struct. Equ. Model. 27, 765\u2013772 (2020).","journal-title":"Struct. Equ. Model."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-13641-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-13641-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-13641-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T07:43:15Z","timestamp":1757317395000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-13641-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,30]]},"references-count":50,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["13641"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-13641-9","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,30]]},"assertion":[{"value":"10 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study was approved by the Research Ethics Committees of the CHU de Qu\u00e9bec-Universit\u00e9 Laval and the McGill University (registration number: F9-42434).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"27805"}}