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The University of Oxford waived approval. Additional ethical approval was received for this sub-study from the UCT HREC (HREC\/REF: 092\/2019). No additional data were collected other than those approved in the parent study. Written informed consent and assent were given by guardians and participants, respectively. Participants who were 18 years old and above consented independently at the time of enrolment. All data obtained and generated during the study were kept confidential. This research was conducted in accordance with the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}],"article-number":"39175"}}