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The use of these samples from a biobank for research studies was approved by the ethical committee of the Medical University of Vienna (EK 1636\/2019 and 1123\/2015). All patients or their legal representatives gave written informed consent to participate in the study and all methods were performed in accordance with the relevant guidelines and regulation.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare that this study received funding from Roche Austria GmbH (to MR). The funder was not involved in the study design, analysis, or critical revision of the article for important intellectual content. RH reports speaker honoraria from UCB and BMS. The Medical Universities of Innsbruck (Austria; employer of MR) and Vienna (Austria; employer of RH) receive payments for antibody assays and for antibody validation experiments organized by Euroimmun (L\u00fcbeck, Germany). SB, QY, JH, VE and MB declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"43346"}}